Kyla L Naylor, Amit X Garg, Guangyong Zou, Lisa Langsetmo, William D Leslie, Lisa-Ann Fraser, Jonathan D Adachi, Suzanne Morin, David Goltzman, Brian Lentle, Stuart A Jackson, Robert G Josse, Sophie A Jamal
BACKGROUND AND OBJECTIVES: The Fracture Risk Assessment Tool (FRAX) is widely used to predict the 10-year probability of fracture; however, the clinical utility of FRAX in CKD is unknown. This study assessed the predictive ability of FRAX in individuals with reduced kidney function compared with individuals with normal kidney function. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The discrimination and calibration (defined as the agreement between observed and predicted values) of FRAX were examined using data from the Canadian Multicentre Osteoporosis Study (CaMos)...
April 7, 2015: Clinical Journal of the American Society of Nephrology: CJASN