Wireko Andrew Awuah, Sakshi Roy, Joecelyn Kirani Tan, Favour Tope Adebusoye, Zekai Qiang, Tomas Ferreira, Arjun Ahluwalia, Vallabh Shet, Amanda Leong Weng Yee, Toufik Abdul-Rahman, Marios Papadakis
Gastric cancer (GC) represents a major global health burden and is responsible for a significant number of cancer-related fatalities. Its complex nature, characterized by heterogeneity and aggressive behaviour, poses considerable challenges for effective diagnosis and treatment. Single-cell RNA sequencing (scRNA-seq) has emerged as an important technique, offering unprecedented precision and depth in gene expression profiling at the cellular level. By facilitating the identification of distinct cell populations, rare cells and dynamic transcriptional changes within GC, scRNA-seq has yielded valuable insights into tumour progression and potential therapeutic targets...
April 2024: Journal of Cellular and Molecular Medicine