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Infectious Diseases Guidelines

Stacy A Trent, Zachary J Jarou, Edward P Havranek, Adit A Ginde, Jason S Haukoos
OBJECTIVES: Evidence-based clinical practice guidelines (CPGs) for the treatment of pneumonia and sepsis have existed for many years with multiple studies suggesting improved patient outcomes. Despite their importance, little is known about variation in emergency department (ED) adherence to these CPGs. Our objectives were to estimate variation in ED adherence across CPGs for pneumonia and sepsis, and identify patient, provider, and environmental factors associated with adherence. METHODS: Design: Multicenter retrospective study using standard medical record review methods...
October 21, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
G T Chua, P H Li, M Hk Ho, E Lai, V Ngai, F Ys Yau, M Yw Kwan, T F Leung, T H Lee
Vaccination of egg-allergic individuals has been a historical concern, particularly for influenza and measles-mumps-rubella-varicella vaccines that are developed in chicken egg embryos or chicken cell fibroblasts. The egg proteins in these vaccines were believed to trigger an immediate allergic reaction in egg-allergic individuals. However, recently published international guidelines have updated their recommendations and now state that these vaccines can be safely administered to egg-allergic individuals. This joint consensus statement by the Hong Kong Institute of Allergy and the Hong Kong Society for Paediatric Immunology Allergy & Infectious Diseases summarises the updates and provides recommendations for local general practitioners and paediatricians...
October 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
(no author information available yet)
End-stage liver disease (ESLD) is a life threaten clinical syndrome with significantly increasing mortality when patients complicated with infections. For patients with ESLD, infections can induce or aggravate the occurrence of liver decompensation. In turn, infections are among the most common complications under, disease progression. There is lacking of working procedures for early diagnosis and appropriate management for patients of ESLD complicated with infections, neither guidelines nor consensus at home and abroad...
August 20, 2018: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
Josephine Mauskopf, Baudouin Standaert, Mark P Connolly, Anthony J Culyer, Louis P Garrison, Raymond Hutubessy, Mark Jit, Richard Pitman, Paul Revill, Johan L Severens
This report provides recommendations for budget holders and decision makers in high-, middle, and low-income countries requiring economic analyses of new vaccination programs to allocate scarce resources given budget constraints. ISPOR's Economic Evaluation of Vaccines Designed to Prevent Infectious Disease: Good Practices Task Force wrote guidelines for three analytic methods and solicited comments on them from external reviewers. Cost-effectiveness analyses use decision-analytic models to estimate cumulative changes in resource use, costs, and changes in quality- or disability-adjusted life-years attributable to changes in disease outcomes...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Bárbara Saú Rechelo, Ana Carolina Kogawa, Hérida Regina Nunes Salgado
Cefazolin sodium is a broad-spectrum antibiotic used in the treatment of infectious diseases in humans and in the surgical prophylaxis. Thus, since a considerable number of people have access to this drug, it is of great interest of quality control. The aim of this study was development and validation of a green method by Fourier-Transform Infrared (FT-IR) transmission spectrophotometry for the quantification of cefazolin sodium in lyophilized powder. This technique is widely used in the pharmaceutical industry due to its ease of execution, low cost, safety and high precision and accuracy...
October 6, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Jinlin Hou, Fuqiang Cui, Yang Ding, Xiaoguang Dou, Zhongping Duan, Guorong Han, Jidong Jia, Qing Mao, Jie Li, Zengde Li, Zhihua Liu, Lai Wei, Qing Xie, Xizhong Yang, Hua Zhang, Hui Zhuang
In areas where hepatitis B virus (HBV) is endemic, mother to child transmission (MTCT) is the major route of infection of children. Blocking MTCT of HBV would therefore reduce its prevalence. The China Foundation of Hepatitis Prevention and Control organized a team of specialists in infectious diseases, hepatology, immunology, obstetrics, and public health to develop an algorithm for interrupting MTCT of HBV, based on the most recent hepatitis B guidelines and latest evidence. This algorithm comprises 10 steps and has been adopted in clinical practice in China...
October 9, 2018: Clinical Gastroenterology and Hepatology
Charlie Tan, Mark S Hansen, Gideon Cohen, Karl Boyle, Alvin Yang, Asgar Rishu, Ruxandra Pinto, Neill K J Adhikari, Nick Daneman
BACKGROUND: A multidisciplinary approach has been recommended for the management of patients with infective endocarditis. We evaluated the impact of multidisciplinary case conferences on morbidity, mortality, and quality of care for these patients. METHODS: We conducted a quasi-experimental study of consecutive patients admitted for infective endocarditis before (2013/10/1-2015/10/12, n = 97) and after (2015/10/13-2017/11/30, n = 80) implementation of case conferences to discuss medical and surgical management...
2018: PloS One
Marie-Michèle Gaudreault-Tremblay, Catherine Litalien, Natalie Patey, Aicha Merouani
Rationale: Acute tubulointerstitial nephritis (ATIN) in children is most commonly due to allergic drug reactions. In neonates, diagnosis of ATIN is clinically suspected and a kidney biopsy is not routinely performed. Presenting concern: A 17-day-old newborn presented with vomiting and dehydration, along with anuric acute kidney injury, severe electrolyte disturbances, hypocomplementemia, and thrombocytopenia. Abdominal ultrasound revealed bilateral nephromegaly and hepatosplenomegaly...
2018: Canadian Journal of Kidney Health and Disease
Maryam Raeispour, Reza Ranjbar
Background: The way of treating different types of infectious diseases is really important. Using genotyping method, we can determine the genetic relatedness between the organisms with different resistance profile from different sources. The aim of this study was to determine antibiotic resistance and genotyping of uropathogenic Escherichia coli (UPEC) strains using pulsed field gel electrophoresis (PFGE). Method: Escherichia coli ( E. coli ) strains were recovered from the patients with urinary tract infections (UTI) whom admitted in several major hospitals in Tehran...
2018: Antimicrobial Resistance and Infection Control
Charles R Sims, Matthew A Warner, Henry Thomas Stelfox, Joseph A Hyder
OBJECTIVES: We examined recommendations within critical care guidelines to describe the pairing patterns for strength of recommendation and quality of evidence. We further identified recommendations where the reported strength of recommendation was strong while the reported quality of evidence was not high/moderate and then assessed whether such pairings were within five paradigmatic situations offered by Grading of Recommendations Assessment, Development and Evaluation methodology to justify such pairings...
October 9, 2018: Critical Care Medicine
Cesare Hassan, Lars Aabakken, Alanna Ebigbo, John Gásdal Karstensen, Claire Guy, Mario Dinis-Ribeiro, Olivier Le Moine, Peter Vilmann, Thierry Ponchon
A new objective for the European Society of Gastrointestinal Endoscopy (ESGE) is to develop long-term partnerships with African countries. For this, an International Affairs Working Group (IAWG) was formed. In conjunction with the World Endoscopy Organization (WEO), ESGE conducted a survey of gastrointestinal (GI) endoscopy in Africa. Survey results showed that many African countries have few GI endoscopy centers with adequate resources. Barriers to the development of endoscopy services include a shortage of endoscopists who have undergone advanced endoscopy training, and a lack of equipment and basic infrastructure...
October 2018: Endoscopy International Open
Jose Tiago Silva, Mario Fernández-Ruiz, Jose Maria Aguado
PURPOSE OF REVIEW: Solid organ transplantation (SOT) is the best therapeutic option for both acute and chronic end-stage diseases. The development of more potent and safer immunosuppressants and the improvement of prophylactic practices have significantly diminished the morbidity and mortality associated with rejection and opportunistic infections. However, infections produced by multidrug-resistant (MDR) Gram-negative bacilli (GNB) have recently emerged as a significant threat. RECENT FINDINGS: The Spanish Society of Transplantation (SET), the Group for Study of Infection in Transplantation of the Spanish Society of Infectious Diseases and Clinical Microbiology (GESITRA-SEIMC) and the Spanish Network for Research in Infectious Diseases (REIPI) have recently published their recommendations concerning the management of MDR GNB infections in SOT recipients...
October 6, 2018: Current Opinion in Infectious Diseases
Elena Beam, Raymund R Razonable
There are no standard guidelines for infection prevention and control practices among solid organ transplantation centers. To characterize the differences in infection prevention and control strategies, an electronic survey was performed in 2015 among members of American Society of Transplantation Infectious Diseases Community of Practice. These results highlight notable practice differences.
October 4, 2018: American Journal of Infection Control
Jennifer Coukos, Francis A Farraye
PURPOSE OF REVIEW: Patients with inflammatory bowel disease (IBD) are at increased risk of infectious diseases independent of their immunosuppression status, and yet, studies suggest that this population is not receiving standard vaccinations at the same rate as the general population. This review seeks to understand why IBD patients may not be receiving recommended immunizations and to provide guidelines on vaccinating this vulnerable population. RECENT FINDINGS: Inactive vaccines are recommended for patients with IBD regardless of immunosuppression status due to the increased risk for many vaccine-preventable illnesses...
October 6, 2018: Current Treatment Options in Gastroenterology
Musomba Rachel, Castelnuovo Barbara, Claire Murphy, Charlene Komujuni, Patience Nyakato, Ponsiano Ocama, Mohammed Lamorde, Philippa Easterbrook, Rosalind Parkes Ratanshi
Background: WHO hepatitis B guidelines recommend testing all new HIV patients, treating them accordingly or providing immunization. At the Infectious Diseases Institute (IDI) following an audit done in 2012, only 46% patients had been screened for hepatitis B with variable management plans therefore new internal guidelines were implemented. This study describes the uptake of hepatitis B screening and management of patients with hepatitis B and HIV con-infection after the implementation...
2018: Hepatology, Medicine and Policy
Debra A O'Leary, Eleanor Cropp, David Isaac, Paul V Desmond, Sally Bell, Tin Nguyen, Darren Wong, Jessica Howell, Jacqui Richmond, Jenny O'Neill, Alexander J Thompson
Background: The current model of care for the treatment of chronic hepatitis B (CHB) in Australia is through specialist Hepatology or Infectious Diseases clinics, and limited accredited primary care practices. Capacity is limited, and less than 5% of Australians living with CHB currently access therapy. Increasing treatment uptake is an urgent area of clinical need. Nucleos(t)ide analogue therapy is safe and effective treatment for CHB that is suitable for community prescribing. We have evaluated the success of a community-based model for the management of CHB in primary care clinics using a novel web-based clinical tool...
2018: Hepatology, Medicine and Policy
Rachael A Lee, Joanna Zurko, Bernard C Camins, Russell L Griffin, J Martin Rodriguez, Todd P McCarty, Justine Magadia, Peter G Pappas
Candidemia has a high attributable mortality. The objective of this study was to determine the impact of infectious disease consultation on mortality and clinical outcomes in candidemia. Infectious disease consultation was associated with better adherence to guidelines and improved survival, even in patients with high APACHE II scores.
October 3, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Erica L Ditkoff, Marissa Theofanides, Carrie Mlynarczyk Aisen, Casey G Kowalik, Joshua A Cohn, Wilson Sui, Matthew Rutman, Rony A Adam, Roger R Dmochowski, Kimberly L Cooper
INTRODUCTION: Evidence-based screening and treatment for bacteriuria is crucial to prevent increasing antibiotic resistance. The Infectious Disease Society of America (IDSA) previously released guidelines on the management of asymptomatic bacteriuria (ASB) and uncomplicated urinary tract infections (UTIs) in women. The study's objective was to assess physicians' practices in managing women with bacteriuria relative to these guideline recommendations. MATERIALS AND METHODS: Cross-sectional data from physicians were collected using an anonymous questionnaire...
October 2018: Canadian Journal of Urology
Xing-Wang Li, Xin Ni, Su-Yun Qian, Quan Wang, Rong-Meng Jiang, Wen-Bo Xu, Yu-Cai Zhang, Guang-Jun Yu, Qiang Chen, Yun-Xiao Shang, Cheng-Song Zhao, Hui Yu, Ting Zhang, Gang Liu, Hui-Ling Deng, Jie Gao, Xian-Gui Ran, Qiao-Zhi Yang, Bian-Li Xu, Xue-Yong Huang, Xing-Dong Wu, Yi-Xiao Bao, Yi-Ping Chen, Zhi-Hai Chen, Qing-Quan Liu, Guo-Ping Lu, Chun-Feng Liu, Rong-Bing Wang, Guo-Liang Zhang, Fang Gu, Hong-Mei Xu, Ying Li, Tao Yang
BACKGROUND: Hand, foot, and mouth disease (HFMD) is a common infectious disease in childhood caused by an enterovirus (EV), and which is principally seen in children under 5 years of age. To promote diagnostic awareness and effective treatments, to further standardize and strengthen the clinical management and to reduce the mortality of HFMD, the guidelines for diagnosis and treatment have been developed. METHODS: National Health Commission of China assembled an expert committee for a revision of the guidelines...
October 2018: World Journal of Pediatrics: WJP
Elisa Lucchini, Renato Fanin, Nichola Cooper, Francesco Zaja
Despite the improvement in understanding its pathogenesis and the introduction of novel treatment options, the management of primary immune thrombocytopenia (ITP) still remains challenging. Considering its increased incidence with aging and prolonged life-expectancy, ITP is often diagnosed in elderly patients, a subset that deserves some special precautions. Ensure the diagnosis is a crucial step, and carefully attention must be given in excluding other causes of thrombocytopenia, especially among older people that frequently suffer from many comorbidities...
September 29, 2018: European Journal of Internal Medicine
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