keyword
MENU ▼
Read by QxMD icon Read
search

Diuretics in chf

keyword
https://www.readbyqxmd.com/read/30543707/taurine-deficiency-and-dilated-cardiomyopathy-in-golden-retrievers-fed-commercial-diets
#1
Joanna L Kaplan, Joshua A Stern, Andrea J Fascetti, Jennifer A Larsen, Hannah Skolnik, Gordon D Peddle, Richard D Kienle, Andrew Waxman, Michael Cocchiaro, Catherine T Gunther-Harrington, Tyler Klose, Kendra LaFauci, Bonnie Lefbom, Maggie Machen Lamy, Rebecca Malakoff, Satoko Nishimura, Maureen Oldach, Steven Rosenthal, Christopher Stauthammer, Lynne O'Sullivan, Lance C Visser, Regan William, Eric Ontiveros
INTRODUCTION: Golden retrievers are over-represented in cases of taurine-deficient dilated cardiomyopathy and recently a surge in cases has prompted further investigation. OBJECTIVE: To describe the clinical, dietary, and echocardiographic features in golden retrievers diagnosed with taurine deficiency and dilated cardiomyopathy, and to determine specific dietary associations. A second aim was to determine the whole blood taurine concentrations in a representative sample of healthy golden retrievers...
2018: PloS One
https://www.readbyqxmd.com/read/30443423/bayesian-network-model-to-evaluate-the-effectiveness-of-continuous-positive-airway-pressure-treatment-of-sleep-apnea
#2
Olli-Pekka Ryynänen, Timo Leppänen, Pekka Kekolahti, Esa Mervaala, Juha Töyräs
Objectives: The association between obstructive sleep apnea (OSA) and mortality or serious cardiovascular events over a long period of time is not clearly understood. The aim of this observational study was to estimate the clinical effectiveness of continuous positive airway pressure (CPAP) treatment on an outcome variable combining mortality, acute myocardial infarction (AMI), and cerebrovascular insult (CVI) during a follow-up period of 15.5 years (186 ± 58 months). Methods: The data set consisted of 978 patients with an apnea-hypopnea index (AHI) ≥5...
October 2018: Healthcare Informatics Research
https://www.readbyqxmd.com/read/30372154/effects-of-furosemide-administration-to-water-deprived-inland-bearded-dragons-pogona-vitticeps
#3
Lily A Parkinson, Christoph Mans
OBJECTIVE To evaluate the diuretic effects and associated changes in hematologic and plasma biochemical values following SC furosemide administration to water-deprived inland bearded dragons (Pogona vitticeps). ANIMALS 9 bearded dragons. PROCEDURES In a crossover study design, furosemide (5 or 10 mg/kg) was administered SC every 12 hours for 4 doses or no treatment (control treatment) was provided for the same period. Food and water were withheld. Body weight was recorded before (baseline) and 12 hours after treatment sessions ended and then after 5 minutes of soaking in a water bath...
November 2018: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/30345343/right-ventricular-enlargement-predicts-responsiveness-to-tolvaptan-in-congestive-heart-failure-patients-with-reduced-ejection-fraction
#4
Shinichi Nonin, Shinichi Iwata, Asahiro Ito, Soichiro Tamura, Ryoko Kitada, Yu Kawai, Sera Ishikawa, Atsushi Doi, Akihisa Hanatani, Minoru Yoshiyama
Background: Tolvaptan is a vasopressin type 2 receptor antagonist used in heart failure (HF) with refractory diuretic resistance. However, since tolvaptan is also ineffective in some HF patients with reduced ejection fraction (HFrEF), the identification of responders is important. Methods: The study population consisted of 51 HFrEF patients who were administered tolvaptan (EF, 28 ± 7%). We defined responders as patients with a ≥50% increase in urine volume during the 24-hours after administration of tolvaptan...
December 2018: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/30309460/diuretics-in-the-management-of-cardiorenal-syndrome
#5
REVIEW
Chandrika Chitturi, James E Novak
The leading cause of death worldwide is cardiovascular disease. The heart and the kidneys are functionally interdependent, such that dysfunction in one organ may cause dysfunction in the other. By one estimate, more than 60% of patients with congestive heart failure develop chronic kidney disease. Volume overload and congestion are hallmarks of heart failure, and these findings are associated with severe symptoms and poor outcomes. Given the importance of congestion, diuretics remain a cornerstone of heart failure management...
September 2018: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/30259172/different-diuretic-properties-between-tolvaptan-and-furosemide-in-congestive-heart-failure-patients-with-diuretic-resistance-and-renal-impairment-a-subanalysis-of-the-k-star
#6
Yuki Ikeda, Takayuki Inomata, Keisuke Kida, Yugo Shibagaki, Naoki Sato, Tohru Izumi, Junya Ako
We attempted to identify the difference in diuretic properties between tolvaptan (TLV) and furosemide (FUR) in congestive heart failure (CHF) patients with loop diuretic resistance and renal impairment. We investigated 81 CHF patients with loop diuretic treatment and renal impairment included in t he Kanagawa Aquaresis Investigators Trial of Tolvaptan on Heart Failure Patients with Renal Impairment (K-STAR). Predictive baseline factors and their changes during treatment periods were analyzed for correlation with percentage change in urine volume (%ΔUV) after additive introduction of TLV or increasing doses of FUR...
September 26, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/30216549/effect-of-prespecified-therapy-escalation-on-plasma-nt-probnp-concentrations-in-dogs-with-stable-congestive-heart-failure-due-to-myxomatous-mitral-valve-disease
#7
Melanie J Hezzell, Chloë L Block, Danielle S Laughlin, Mark A Oyama
BACKGROUND: Treatment targeted to achieve reduction in N-terminal pro-B-type natriuretic peptide (NT-proBNP) improves outcomes in human congestive heart failure (CHF) patients. HYPOTHESIS: A pre-specified therapeutic algorithm that increased diuretic or pimobendan usage will reduce plasma NT-proBNP concentrations in dogs with CHF secondary to myxomatous mitral valve disease (MMVD). ANIMALS: Twenty-six dogs with clinically stable CHF secondary to MMVD...
September 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/30191652/use-of-acetazolamide-in-the-treatment-of-patients-with-refractory-congestive-heart-failure
#8
Julio Núñez, Raquel Heredia, Ana Payá, Ignacio Sanchis, Susana Del Prado, Gema Miñana, Enrique Santas, Rafael de la Espriella, Eduardo Núñez, Juan Sanchis, Antoni Bayés-Genís
AIMS: Optimal diuretic treatment of patients with refractory congestive heart failure (CHF) remains to be elucidated. In this work, we aimed to evaluate the serial changes of functional class and surrogates of fluid overload (weight and antigen carbohydrate 125) after addition of oral acetazolamide in patients with refractory CHF. Likewise, serial changes in renal function, serum electrolytes and pH were evaluated. METHOD: This is an observational retrospective study in which 25 ambulatory patients with refractory CHF that received acetazolamide in addition to standard intensive diuretic strategy were evaluated...
September 6, 2018: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/30134838/endovascular-treatment-of-transplant-renal-artery-stenosis-based-on-hemodynamic-assessment-using-a-pressure-wire-a-case-report
#9
Yoshito Kadoya, Kan Zen, Satoaki Matoba
BACKGROUND: Transplant renal artery stenosis (TRAS) is a serious complication after renal transplantation, leading to hypertension, deterioration in renal function, and/or graft loss. The incidence of TRAS reportedly varies from 1 to 23%, depending on its definition or diagnostic tools. The hemodynamic definition or therapeutic indication of TRAS is unclear. CASE PRESENTATION: A 66-year-old man with a history of diabetes, chronic kidney disease, and angina presented with a 2-week history of dyspnea and leg edema...
August 22, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/30121806/vitamin-d-deficiency-is-an-independent-predictor-of-mortality-in-patients-with-chronic-heart-failure
#10
Richard M Cubbon, Judith E Lowry, Michael Drozd, Marlous Hall, John Gierula, Maria F Paton, Rowena Byrom, Lorraine C Kearney, Julian H Barth, Mark T Kearney, Klaus K Witte
PURPOSE: Low 25-hydroxyvitamin D (25[OH]D) concentrations have been associated with adverse outcomes in selected populations with established chronic heart failure (CHF). However, it remains unclear whether 25[OH]D deficiency is associated with mortality and hospitalisation in unselected patients receiving contemporary medical and device therapy for CHF. METHODS: We prospectively examined the prevalence and correlates of 25[OH]D deficiency in 1802 ambulatory patients with CHF due to left ventricular systolic dysfunction (left ventricular ejection fraction ≤ 45%) attending heart failure clinics in the north of England...
August 18, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/30087772/medication-discrepancies-in-late-stage-chronic-kidney-disease
#11
Jamil Ibrahim, Azzour D Hazzan, Anna T Mathew, Vipul Sakhiya, Meng Zhang, Candice Halinski, Steven Fishbane
Background: Late-stage chronic kidney disease (LS-CKD) can be defined by glomerular filtration rate (GFR) 0-30 mL/min. It is a period of risk for medication discrepancies because of frequent hospitalizations, fragmented medical care, inadequate communication and polypharmacy. In this study, we sought to characterize medication discrepancies in LS-CKD. Methods: We analyzed all patients enrolled in Northwell Health's Healthy Transitions in LS-CKD program. All patients had estimated GFR 0-30 mL/min, not on dialysis...
August 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/30052224/refractory-hypokalemia-while-weaning-off-bypass
#12
Rashmi Soori, Aanchal Dixit, Prabhat Tewari
Hypokalemia is defined as serum potassium level less than 3.5 mEq/L. When the serum level of potassium is less than 3 mEq/L, intravenous potassium supplementation is warranted. A 23 yr old adult female with complaints of dyspnoea (NYHA II) since 6 yrs, dyspnoea (NYHA III) and paroxysmal nocturnal dyspnoea on and off since 2 months, diagnosed with severe mitral stenosis, was posted for mitral valve replacement. After the release of ACC, ECG revealed sine wave pattern, Transesophageal echocardiographic examination revealed global hypokinesia and ABG showed potassium of 2...
July 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/30033126/an-evaluation-of-a-potential-calcium-channel-blocker-lower-extremity-edema-loop-diuretic-prescribing-cascade
#13
Scott Martin Vouri, Joseph S van Tuyl, Margaret A Olsen, Hong Xian, Mario Schootman
OBJECTIVES: Dihydropyridine calcium channel blockers (DH-CCB) are associated with lower-extremity edema (LEE). Loop diuretics have been used inappropriately to treat DH-CCB-associated LEE, constituting a prescribing cascade (PC). The aim of this work was to identify the prevalence and factors associated with potential DH-CCB-LEE-loop diuretic PC. METHODS: The 2014 National Ambulatory Medical Care Survey was used to identify patient visits in which a DH-CCB was continued...
September 2018: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29943886/low-serum-chloride-in-patients-with-chronic-heart-failure-clinical-associations-and-prognostic-significance
#14
Joseph J Cuthbert, Pierpaolo Pellicori, Alan Rigby, Daniel Pan, Syed Kazmi, Parin Shah, Andrew L Clark
BACKGROUND: Low serum chloride is common in patients with chronic heart failure (CHF) and is associated with worse outcomes. We investigated the clinical and prognostic associations, including cause of death associations, of low serum chloride in patients referred to a secondary care clinic with suspected heart failure. METHODS AND RESULTS: Patients with echocardiogram and serum chloride were evaluated (n = 5613). CHF was defined as signs and symptoms of the disease and either left ventricular systolic dysfunction (LVSD) worse than mild [heart failure with reduced ejection fraction (HFrEF)] or LVSD mild or better and raised amino-terminal pro-B-type natriuretic peptide (NT-proBNP) levels (>125 ng/L) [heart failure with preserved ejection fraction (HFpEF)]...
June 26, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29896315/novel-concept-to-guide-systolic-heart-failure-medication-by-repeated-biomarker-testing-results-from-time-chf-in-context-of-predictive-preventive-and-personalized-medicine
#15
Nasser Davarzani, Sandra Sanders-van Wijk, Micha T Maeder, Peter Rickenbacher, Evgueni Smirnov, Joël Karel, Thomas Suter, Rudolf A de Boer, Dirk Block, Vinzent Rolny, Christian Zaugg, Matthias E Pfisterer, Ralf Peeters, Hans-Peter Brunner-La Rocca
Background: It is uncertain whether repeated measurements of a multi-target biomarker panel may help to personalize medical heart failure (HF) therapy to improve outcome in chronic HF. Methods: This analysis included 499 patients from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF), aged ≥ 60 years, LVEF ≤ 45%, and NYHA ≥ II, who had repeated clinical visits within 19 months follow-up...
June 2018: EPMA Journal
https://www.readbyqxmd.com/read/29870433/associations-between-relevant-cardiovascular-pharmacotherapies-and-incident-heart-failure-in-patients-with-atrial-fibrillation-a-cohort-study-in-primary-care
#16
Per Wändell, Axel C Carlsson, Martin J Holzmann, Johan Ärnlöv, Jan Sundquist, Kristina Sundquist
OBJECTIVE: To study association between relevant cardiovascular pharmacotherapy and incident congestive heart failure (CHF) in patients with atrial fibrillation treated in primary health care. METHODS: Study population included all adults (n = 7975) aged 45 years and older diagnosed with atrial fibrillation at 75 primary care centers in Sweden between 2001 and 2007. Outcome was defined as a first diagnosis of CHF post-atrial fibrillation diagnosis. Association between CHF and treatment with relevant cardiovascular pharmacotherapies (beta blockers, calcium blockers, digitalis, diuretics, RAS blockers, and statins) was explored using Cox regression analysis with hazard ratios and 95% CIs...
September 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29846031/pharmacy-based-interdisciplinary-program-for-patients-with-chronic-heart-failure-pharm-chf-rationale-and-design-of-a-randomized-controlled-trial-and-results-of-the-pilot-study
#17
Ulrich Laufs, Nina Griese-Mammen, Katrin Krueger, Angelika Wachter, Stefan D Anker, Friedrich Koehler, Volker Rettig-Ewen, Lea Botermann, Dorothea Strauch, Dietmar Trenk, Michael Böhm, Martin Schulz
We report the rationale and design of a community PHARMacy-based prospective randomized controlled interdisciplinary study for ambulatory patients with Chronic Heart Failure (PHARM-CHF) and results of its pilot study. The pilot study randomized 50 patients to a pharmacy-based intervention or usual care for 12 months. It demonstrated the feasibility of the design and showed reduced systolic blood pressure in the intervention group as indicator for improved medication adherence. The main study will randomize patients ≥60 years on stable pharmacotherapy including at least one diuretic and a history of heart failure hospitalization within 12 months...
September 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29770976/pharmacokinetic-and-pharmacodynamic-properties-of-orally-administered-torsemide-in-healthy-horses
#18
Gustavo F Agne, Seung Woo Jung, Anne A Wooldridge, Susan H Duran, William Ravis, Ramiro Toribio
BACKGROUND: Diuretic treatment is the mainstay for management of congestive heart failure in horses, and its use has been restricted to injectable medications because no currently data supports the use of PO administered loop diuretics. OBJECTIVES: To determine the pharmacokinetic and pharmacodynamic properties of PO administered torsemide and, determine if PO administered torsemide, could be used as an alternative to injectable diuretics in the horse. ANIMALS: Six healthy adult mares...
July 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29763317/chemoproteomic-profiling-reveals-ethacrynic-acid-targets-adenine-nucleotide-translocases-to-impair-mitochondrial-function
#19
Zi Ye, Xiaoyun Zhang, Yuangang Zhu, Tong Song, Xiaowei Chen, Xiaoguang Lei, Chu Wang
Ethacrynic acid (EA) is a diuretic drug that is widely used to treat high-blood pressure and swelling caused by congestive heart failure or kidney failure. It acts through noncovalent inhibition of the Na+ -K+ -2Cl- cotransporter in the thick ascending limb of Henle's loop. Chemically, EA contains a Michael acceptor group that can react covalently with nucleophilic residues in proteins; however, the proteome reactivity of EA remains unexplored. Herein, we took a quantitative chemoproteomic approach to globally profile EA's targets in cancer cells...
June 4, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29701173/cyclical-cardiorenal-syndrome-in-late-stage-kidney-disease
#20
Benson Ku, Steven Fishbane
INTRODUCTION: In patients with late-stage chronic kidney disease (LS-CKD, estimated glomerular filtration rate (eGFR) < 30 mL/min) there is a high prevalence of congestive heart failure (CHF). We have observed a cyclical nature in the "cardiorenal syndrome" in LS-CKD, not previously described. The purpose of this article is to describe the syndrome and review its characteristics. MATERIALS AND METHODS: Patients enrolled in the Northwell Health Healthy Transitions in Late Stage Kidney Disease Program (HT) were followed, all with eGFR 0 - 30 mL/min...
September 2018: Clinical Nephrology
keyword
keyword
168298
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"