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https://www.readbyqxmd.com/read/29228404/chondrocyte-viability-at-time-of-transplantation-for-osteochondral-allografts-preserved-by-the-missouri-osteochondral-preservation-system-versus-standard-tissue-bank-protocol
#1
Aaron M Stoker, James P Stannard, James L Cook
No abstract text is available yet for this article.
December 11, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29228193/deepsf-deep-convolutional-neural-network-for-mapping-protein-sequences-to-folds
#2
Jie Hou, Badri Adhikari, Jianlin Cheng
Motivation: Protein fold recognition is an important problem in structural bioinformatics. Almost all traditional fold recognition methods use sequence (homology) comparison to indirectly predict the fold of a target protein based on the fold of a template protein with known structure, which cannot explain the relationship between sequence and fold. Only a few methods had been developed to classify protein sequences into a small number of folds due to methodological limitations, which are not generally useful in practice...
December 8, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29228185/dncon2-improved-protein-contact-prediction-using-two-level-deep-convolutional-neural-networks
#3
Badri Adhikari, Jie Hou, Jianlin Cheng
Motivation: Significant improvements in the prediction of protein residue-residue contacts are observed in the recent years. These contacts, predicted using a variety of coevolution-based and machine learning methods, are the key contributors to the recent progress in ab initio protein structure prediction, as demonstrated in the recent CASP experiments. Continuing the development of new methods to reliably predict contact maps is essential to further improve ab initio structure prediction...
December 8, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29225439/exploring-the-obesity-paradox-as-a-correlate-of-cognitive-and-physical-function-in-community-dwelling-black-and-white-older-adults
#4
Jeannine S Skinner, Willie Mae Abel, Katryna McCoy, Consuelo H Wilkins
Objective: The obesity paradox has been documented in aged populations, yet it remains unclear if this paradox persists for physical and cognitive outcomes in community-dwelling older adult populations. Our study examines associations between body mass index (BMI) classification, cognitive function, and physical function. We also investigate whether these associations are modified by race or age. Design: Cross-sectional study. Setting: Senior residential sites and community centers in Saint Louis, Missouri...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/29214316/association-between-hospital-financial-distress-and-immediate-breast-reconstruction-surgery-after-mastectomy-among-women-with-ductal-carcinoma-in-situ
#5
Catherine A Richards, Andrew G Rundle, Jason D Wright, Dawn L Hershman
Importance: Hospital financial distress (HFD) is a state in which a hospital is at risk of closure because of its financial condition. Hospital financial distress may reduce the services a hospital can offer, particularly unprofitable ones. Few studies have assessed the association of HFD with quality of care. Objective: To examine the association between HFD and receipt of immediate breast reconstruction surgery after mastectomy among women diagnosed with ductal carcinoma in situ (DCIS)...
December 6, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29209583/what-makes-the-optimal-wound-healing-material-a-review-of-current-science-and-introduction-of-a-synthetic-nanofabricated-wound-care-scaffold
#6
REVIEW
Matthew R MacEwan, Sarah MacEwan, Tamas R Kovacs, Joel Batts
Wound matrix materials are used to improve the regeneration of dermal and epidermal layers in both acute and chronic wounds. Contemporary wound matrices are primarily composed of biologic materials such as processed xenogeneic and allogeneic tissues. Unfortunately, existing biologic wound matrices possess multiple limitations including poor longevity, durability, strength, and enzymatic resistance required for persistent support for new tissue formation. A fully-synthetic, resorbable electrospun material (Restrata Wound Matrix, Acera, St...
October 2, 2017: Curēus
https://www.readbyqxmd.com/read/29208447/impact-of-advanced-practice-registered-nurses-on-quality-measures-the-missouri-quality-initiative-experience
#7
Marilyn J Rantz, Lori Popejoy, Amy Vogelsmeier, Colleen Galambos, Greg Alexander, Marcia Flesner, Cathy Murray, Charles Crecelius, Bin Ge, Gregory Petroski
PURPOSE: The purpose of this article is to review the impact of advanced practice registered nurses (APRNs) on the quality measure (QM) scores of the 16 participating nursing homes of the Missouri Quality Initiative (MOQI) intervention. The MOQI was one of 7 program sites in the US, with specific interventions unique to each site tested for the Centers for Medicaid and Medicare Services Innovations Center. While the goals of the MOQI for long-stay nursing home residents did not specifically include improvement of the QM scores, it was anticipated that improvement most likely would occur...
December 2, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29197686/the-impact-of-screening-on-cancer-incidence-and-mortality-in-missouri-usa-2004-2013
#8
Y Yoshida, C L Schmaltz, J Jackson-Thompson, E J Simoes
OBJECTIVES: Population-based evidence regarding impact of cancer screenings and cancer rates in Missouri is lacking. This study examined whether screenings of breast cancer, cervical cancer, and colorectal cancer impact early-stage cancer incidence and mortality in Missouri. STUDY DESIGN: This is an ecological study based on county-specific estimates of selected cancer screening prevalence and early-stage cancer incidence and cancer mortality. METHODS: County-specific prevalence of clinical breast examination, mammography, Pap test, sigmoidoscopy or colonoscopy, and fecal occult blood test (FOBT) were generated from Missouri County-Level Study (2003, 2007, and 2011)...
November 30, 2017: Public Health
https://www.readbyqxmd.com/read/29191762/aprn-conducted-medication-reviews-for-long-stay-nursing-home-residents
#9
Amy Vogelsmeier, Lori Popejoy, Charles Crecelius, Sabrina Orique, Greg Alexander, Marilyn Rantz
OBJECTIVE: As part of the Missouri Quality Initiative (MOQI) to reduce hospitalizations for long-stay nursing home residents, this article describes reasons MOQI advanced practice registered nurses (APRNs) recommended medication order changes as part of their medication review process as well as the outcomes of their recommendations. DESIGN: Cross-sectional descriptive study of MOQI APRN-conducted medication reviews. SETTING: Long-stay nursing homes participating in the MOQI project...
November 28, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29187989/resource-selection-by-an-ectothermic-predator-in-a-dynamic-thermal-landscape
#10
Andrew D George, Grant M Connette, Frank R Thompson, John Faaborg
Predicting the effects of global climate change on species interactions has remained difficult because there is a spatiotemporal mismatch between regional climate models and microclimates experienced by organisms. We evaluated resource selection in a predominant ectothermic predator using a modeling approach that permitted us to assess the importance of habitat structure and local real-time air temperatures within the same modeling framework. We radio-tracked 53 western ratsnakes (Pantherophis obsoletus) from 2010 to 2013 in central Missouri, USA, at study sites where this species has previously been linked to prey population demographics...
November 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29182942/does-mntbap-ameliorate-dna-fragmentation-and-in%C3%A2-vivo-fertility-of-frozen-thawed-arabian-stallion-sperm
#11
Kamal Shojaeian, Houshang Nouri, Hamid Kohram
Overproduction of reactive oxygen species during sperm freeze-thawing process leads to membrane lipid peroxidation, DNA damage, motility loss, and subsequent death. This oxidative stress can be alleviated by the addition of some antioxidants to semen extenders prior to freezing. This study was performed to evaluate the in vitro effectiveness of MnTBAP (a cell permeable antioxidant) on stallion sperm freezability and in vivo fertility rate. Twenty-one ejaculates were, collected with missouri model artificial vagina (n = 3 stallions, seven ejaculate each), and diluted (1:2 v/v) with phosphocaseinate base INRA extender, containing 0 (control), 100, 200 and 300 μM of MnTBAP and frozen using acontrolled-rate freezing system...
November 22, 2017: Theriogenology
https://www.readbyqxmd.com/read/29176826/aggregate-level-lead-exposure-gun-violence-homicide-and-rape
#12
Brian B Boutwell, Erik J Nelson, Zhengmin Qian, Michael G Vaughn, John P Wright, Kevin M Beaver, J C Barnes, Melissa Petkovsek, Roger Lewis, Mario Schootman, Richard Rosenfeld
CONTEXT: An increasing body of research has linked the geographic distribution of lead with various indicators of criminal and antisocial behavior. OBJECTIVE: The current study, using data from an ongoing project related to lead exposure in St. Louis City, MO, analyzed the association between aggregate blood lead levels and specific indicators violent crime within the city. DESIGN: Ecological study. SETTING: St. Louis, Missouri...
2017: PloS One
https://www.readbyqxmd.com/read/29173225/preventing-respiratory-viral-transmission-in-long-term-care-knowledge-attitudes-and-practices-of-healthcare-personnel
#13
Caroline A O'Neil, Lindsay Kim, Mila M Prill, Nimalie D Stone, Shikha Garg, H Keipp Talbot, Hilary M Babcock
OBJECTIVE To examine knowledge and attitudes about influenza vaccination and infection prevention practices among healthcare personnel (HCP) in a long-term-care (LTC) setting. DESIGN Knowledge, attitudes, and practices (KAP) survey. SETTING An LTC facility in St Louis, Missouri. PARTICIPANTS All HCP working at the LTC facility were eligible to participate, regardless of department or position. Of 170 full- and part-time HCP working at the facility, 73 completed the survey, a 42.9% response rate. RESULTS Most HCP agreed that respiratory viral infections were serious and that hand hygiene and face mask use were protective...
December 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29170691/does-time-heal-all-wounds-a-case-study-on-rival-perceptions-before-and-after-conference-realignment
#14
Cody T Havard, Daniel L Wann, Timothy D Ryan, Norman O'Neal
The current longitudinal case study investigated how conference realignment and beginning new annual competitions impacted fan rival perceptions for fans of the Texas A&M Aggies, Missouri Tigers, and Texas Christian University Horned Frogs. In particular, fan rival perceptions before and after conference realignment were compared to determine if significant differences were present. Findings indicate that history plays an important role in rivalry as fans of teams sharing longstanding rivalries with schools in their previous conference (i...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/29169735/associations-of-clinically-relevant-levels-of-depressive-symptoms-and-antidepressant-use-with-mortality-in-african-american-health
#15
Li Cao, Daphne Lew, Theodore K Malmstrom, Douglas K Miller
BACKGROUND: The Institute of Medicine has highlighted unequal treatment for African American individuals in health care. We examined the association of underuse of antidepressants in African American individuals with increased mortality. METHODS: We conducted a longitudinal cohort study in Metropolitan St Louis, Missouri, in a population-based study of community-dwelling African American individuals, aged 52 to 68 years. Medication evaluations and clinically relevant levels of depressive symptoms (CRLDS) assessments occurred in 2000 and 2004...
December 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29168970/human-adenovirus-36-seropositivity-and-obesity-among-midwestern-us-adolescents
#16
Aneesh K Tosh, Mollie G Wasserman, Matthew T McLeay Ii, Sara K Tepe
Objective Human adenovirus-36 (Ad-36) infection has been implicated as a risk factor for obesity. This study aims to measure Ad-36 antibody prevalence among obese and healthy-weight Midwestern US adolescents. Methods Obese and healthy-weight subjects 10-18 years of age attending an adolescent clinic in Missouri, USA, were tested for Ad-36 antibodies via ELISA assay. All subjects were measured for height and weight to determine body mass index (BMI). χ2 analysis was used to compare Ad-36 antibody prevalence between the two groups...
November 23, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29167991/a-comparison-of-bioclimatic-potential-in-two-global-regions-during-the-late-twentieth-century-and-early-twenty-first-century
#17
Maria G Lebedeva, Anthony R Lupo, Chasity B Henson, Alexandr B Solovyov, Yury G Chendev, Patrick S Market
Changes in the general circulation of the atmosphere have been taking place during the latter part of the twentieth century and the early part of the twenty-first century. In the Belgorod region of Southwest Russia, this has been manifested in the more frequent occurrence of stationary anticyclones, including those referred to as blocking anticyclones, especially during the summer season. Also, there has been a general increase in regional temperatures during the growing season over the period mentioned above, and combined with the more frequent occurrence of anticyclones has led to less humid conditions...
November 22, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29161523/does-acute-propranolol-treatment-prevent-posttraumatic-stress-disorder-anxiety-and-depression-in-children-with-burns
#18
Laura Rosenberg, Marta Rosenberg, Sherri Sharp, Christopher R Thomas, Helen F Humphries, Charles E Holzer, David N Herndon, Walter J Meyer
OBJECTIVE: This study examined whether acute propranolol treatment prevented posttraumatic stress disorder (PTSD), anxiety, and depression in children hospitalized in the pediatric intensive care unit for large burns. We hypothesized that the prevalence of PTSD, anxiety, and depression would be significantly less in the propranolol than nonpropranolol groups. METHODS: Children who had previously participated in a randomized controlled clinical trial of acute propranolol and nonpropranolol controls were invited to participate in long-term follow-up interviews...
November 21, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29148395/bourbon-virus-in-field-collected-ticks-missouri-usa
#19
Harry M Savage, Kristen L Burkhalter, Marvin S Godsey, Nicholas A Panella, David C Ashley, William L Nicholson, Amy J Lambert
Bourbon virus (BRBV) was first isolated in 2014 from a resident of Bourbon County, Kansas, USA, who died of the infection. In 2015, an ill Payne County, Oklahoma, resident tested positive for antibodies to BRBV, before fully recovering. We retrospectively tested for BRBV in 39,096 ticks from northwestern Missouri, located 240 km from Bourbon County, Kansas. We detected BRBV in 3 pools of Amblyomma americanum (L.) ticks: 1 pool of male adults and 2 pools of nymphs. Detection of BRBV in A. americanum, a species that is aggressive, feeds on humans, and is abundant in Kansas and Oklahoma, supports the premise that A...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29143663/dirofilaria-immitis-jyd-34-isolate-whole-genome-analysis
#20
Catherine Bourguinat, Francois Lefebvre, Johanna Sandoval, Brenda Bondesen, Yovany Moreno, Roger K Prichard
BACKGROUND: Macrocyclic lactone (ML) anthelmintics are used for chemoprophylaxis for heartworm infection in dogs and cats. Cases of dogs becoming infected with heartworms, despite apparent compliance to recommended chemoprophylaxis with approved preventives, has led to such cases being considered as suspected lack of efficacy (LOE). Recently, microfilariae collected from a small number of LOE isolates were used as a source of infection of new host dogs and confirmed to have reduced susceptibility to ML in controlled efficacy studies using L3 challenge in dogs...
November 9, 2017: Parasites & Vectors
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