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Oocyte retrieval

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https://www.readbyqxmd.com/read/30097048/structure-of-preantral-follicles-oxidative-status-and-developmental-competence-of-in-vitro-matured-oocytes-after-ovary-storage-at-4-%C3%A2-c-in-the-domestic-cat-model
#1
Anna Rita Piras, Giovanni Pietro Burrai, Federica Ariu, Laura Falchi, Maria Teresa Zedda, Salvatore Pau, Sergio Domenico Gadau, Elisabetta Antuofermo, Daniela Bebbere, Sergio Ledda, Luisa Bogliolo
BACKGROUND: Storage conditions during transportation of explanted ovaries are a critical step in setting up fertility preservation protocols in both animal and human fields. Here, we evaluated the effects of ovary storage at 4 °C on the preservation of preantral follicles and oocytes retrieved from antral follicles using the domestic cat as model. METHODS: Ovaries were harvested from fifty-five healthy domestic queens during ovariectomy and stored at 4 °C for 0 (control), 24, 48, 72 and 96 h...
August 10, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/30095760/maternal-and-fetal-risk-associated-with-assisted-reproductive-technology
#2
Jennifer F Kawwass, Martina L Badell
Infertility is a disease that affects up to 15.5% of reproductive-aged couples. Until the birth of the first neonate born from in vitro fertilization (IVF) in 1978, many infertile couples did not have an opportunity to conceive a biological child. Over the past 40 years, access to and effectiveness of IVF have increased; currently 1.7% of births in the United States result from IVF. As with any medical intervention, potential risk exists. In the case of IVF, both maternal risks (ovarian stimulation, oocyte retrieval, and subsequent pregnancy) and fetal risks that vary based on maternal age and fetal number must be considered...
August 6, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30094195/ruptured-ectopic-pregnancy-following-a-cycle-of-freeze-all-in-vitro-fertilization-a-case-report
#3
Alyssa Hamlin, Jessica L Bauer, Alex J Polotsky, Shona C Murray
Patients undergoing assisted reproduction are advised to abstain from intercourse to prevent the possibility of multiple pregnancy. If patients do not follow this advice, multiple dizygotic pregnancy or even a heterotopic pregnancy can result. We report the case of a 28-year-old nulliparous female with unexplained infertility who underwent freeze-all vaginal oocyte retrieval. Twenty-one days later she presented with vaginal bleeding (similar to menstruation) and right lower-quadrant pain. The results of ultrasound scanning and a laboratory work-up were consistent with an ectopic pregnancy...
July 2018: Case Reports in Women's Health
https://www.readbyqxmd.com/read/30093488/serum-anti-mullerian-hormone-predicts-ovarian-response-in-macaca-fascicularis-monkeys
#4
Hui Long, Yanhong Nie, Li Wang, Yong Lu, Yan Wang, Yijun Cai, Zhen Liu, Miaomiao Jia, Qifeng Lyu, Yanping Kuang, Qiang Sun
AMH as an accurate predictor of ovarian response has been studied extensively in women undergoing assisted reproductive technology treatment, but little is known about its prediction value in monkeys undergoing ovarian stimulation. In current study, a total of 380 cynomolgus monkeys ranging from 5 to 12 yr received 699 ovarian stimulation cycles. Serum samples were collected for AMH measure with enzyme-linked immunosorbent assay. It was found that serum AMH levels were positive correlated with the number of retrieved oocytes (p<0...
August 9, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/30085894/study-of-the-awareness-of-adoption-as-a-family-building-option-among-oncofertility-stakeholders-in-japan
#5
Eriko Shiraishi, Kouhei Sugimoto, Jason Solomon Shapiro, Yuki Ito, Keiko Kamoshita, Atsuko Kusuhara, Takayuki Haino, Tomoe Koizumi, Aikou Okamoto, Nao Suzuki
Purpose The oncofertility decision tree was developed by the oncofertility consortium as a tool to support healthcare professionals and patients through the complicated process of deciding the most appropriate fertility preservation strategy for patients with cancer. Various strategies include oocyte retrieval, oocyte donation, use of a gestational carrier and adoption. However, differences in the cultural and legal landscape present serious barriers to utilizing some of these strategies in Japan. Patients and Methods We surveyed Japanese oncofertility stakeholders including 60 cancer survivors, 27 oncology facilities, 78 reproductive medicine facilities and 15 adoption agencies by a questionnaire to characterize awareness among oncofertility stakeholders in Japan about parenting options including adoption to inform work to establish guidelines for decision-making by cancer survivors in an oncofertility...
July 2018: Journal of Global Oncology
https://www.readbyqxmd.com/read/30085143/predicting-the-cumulative-chance-of-live-birth-over-multiple-complete-cycles-of-in-vitro-fertilization-an-external-validation-study
#6
J A Leijdekkers, M J C Eijkemans, T C van Tilborg, S C Oudshoorn, D J McLernon, S Bhattacharya, B W J Mol, F J M Broekmans, H L Torrance
STUDY QUESTION: Are the published pre-treatment and post-treatment McLernon models, predicting cumulative live birth rates (LBR) over multiple complete IVF cycles, valid in a different context? SUMMARY ANSWER: With minor recalibration of the pre-treatment model, both McLernon models accurately predict cumulative LBR in a different geographical context and a more recent time period. WHAT IS KNOWN ALREADY: Previous IVF prediction models have estimated the chance of a live birth after a single fresh embryo transfer, thereby excluding the important contribution of embryo cryopreservation and subsequent IVF cycles to cumulative LBR...
August 6, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30084578/the-impact-of-salpingectomy-on-anti-mullerian-hormone-levels-and-ovarian-response-of-in-vitro-fertilization-patients
#7
Ohad Gluck, Liliya Tamayev, Maya Torem, Jacob Bar, Arieh Raziel, Ron Sagiv
BACKGROUND: Laparoscopic salpingectomy is strongly related to successful in vitro fertilization (IVF) treatments. OBJECTIVES: To compare the ovarian reserve, including anti-mullerian hormone (AMH) levels, in patients who underwent salpingectomy before IVF to IVF patients who had not been salpingectomized. METHODS: In this retrospective study, medical records of women who were treated by the IVF unit at our institute were reviewed. We retrieved demographic data, surgical details, and data regarding the ovarian reserve...
August 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/30083428/impact-of-central-obesity-on-women-with-polycystic-ovary-syndrome-undergoing-in-vitro-fertilization
#8
Yu Li, Haiyan Lin, Ping Pan, Dongzi Yang, Qingxue Zhang
Central obesity (CO) is a defining characteristic of polycystic ovary syndrome (PCOS) and PCOS-induced disorders are likely to be exacerbated in the presence of CO. This study aims to evaluate the impact of CO on infertile women with PCOS undergoing in vitro fertilization (IVF).It is a retrospective and case-control study. One hundred eighty-eight infertile PCOS women undergoing IVF were divided into CO group ( n  = 70, waist circumference [WC] ≥80 cm) and noncentral obesity (NCO) group ( n  = 118, WC <80 cm)...
2018: BioResearch Open Access
https://www.readbyqxmd.com/read/30083131/the-effect-of-dose-adjustments-in-a-subsequent-cycle-of-women-with-suboptimal-response-following-conventional-ovarian-stimulation
#9
Panagiotis Drakopoulos, Samuel Santos-Ribeiro, Ernesto Bosch, Juan Garcia-Velasco, Christophe Blockeel, Alessia Romito, Herman Tournaye, Nikolaos P Polyzos
Several infertile patients, who may even represent around 40% of the infertile cohort, may respond "suboptimally" (4-9 oocytes retrieved) following IVF, despite being predicted as normal responders. The aim of our longitudinal study was to evaluate the ovarian response of suboptimal responders in terms of the number of oocytes retrieved, following their second IVF cycle, evaluating exclusively patients who had the same stimulation protocol and used the same or higher initial dose of the same type of gonadotropin compared to their previous failed IVF attempt...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/30078420/the-impact-of-music-therapy-on-pain-and-stress-reduction-during-oocyte-retrieval-a-randomized-controlled-trial
#10
Cosy Wing Ching Cheung, Alice Wong Wai Yee, Pui Shan Chan, Sotirios H Saravelos, Jacqueline Pui Wah Chung, Lai Ping Cheung, Grace Wing Shan Kong, Tin-Chiu Li
RESEARCH QUESTION: Does music therapy help in reducing pain and anxiety in women undergoing transvaginal ultrasound-guided oocyte retrieval (TUGOR)? DESIGN: In this randomized controlled open label study, 209 participants were recruited and randomized into three groups (music group, n = 70; headphone group, n = 70; control group, n = 69). Patients' psychological status was assessed using the visual analogue scale of pain (VAS-P), satisfaction of pain control, state-trait anxiety inventory (STAI), Beck depression inventory (BDI), and general health questionnaire (GHQ)...
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30074220/effect-of-progestin-primed-ovarian-stimulation-protocol-on-outcomes-of-aged-infertile-women-who-failed-to-get-pregnant-in-the-first-ivf-icsi-cycle-a-self-controlled-study
#11
Yin-Mei Chen, Qian-Rong Qi, Qing-Zhen Xie, Yi-Fan Yang, Yi Xia, Xiao-Dan Zhou
This study aimed to explore the outcomes of progestin-primed ovarian stimulation protocol (PPOS) in aged infertile women who failed to get pregnant in the first IVF/ICSI-ET cycles with GnRH-a long protocol. A self-controlled study was conducted to retrospectively investigate the clinical outcomes of 104 aged infertile patients who didn't get pregnant in the first IVF/ICSI-ET treatment by stimulating with GnRH-a long protocol (non-PPOS group), and underwent PPOS protocol (PPOS group) in the second cycle between January 2016 and December 2016 in the Center for Reproductive Medicine, Renmin Hospital of Wuhan University...
June 2018: Current medical science
https://www.readbyqxmd.com/read/30074162/role-of-icsi-in-non-male-factor-cycles-as-the-number-of-oocytes-retrieved-decreases-from-four-to-one
#12
Na Guo, Xiang Hua, Yu-Feng Li, Lei Jin
This study aimed to investigate whether intracytoplasmic sperm injection (ICSI) shows an advantage over in vitro fertilization (IVF) in non-male factor cycles as the number of oocytes retrieved decreases from four to one. We undertook a retrospective analysis of 1305 IVF/ICSI cycles of non-male factor in which four or fewer oocytes were retrieved. Comparisons were made between conventional IVF (CI) and ICSI when one, two, three or four oocyte(s) were retrieved. Primary outcomes including normal fertilization rate, proportion of embryos per obtained oocyte, cycle cancellation rate, implantation rate, clinical pregnancy rate (PR), live birth rate (LBR), cumulative PR and cumulative LBR were evaluated...
February 2018: Current medical science
https://www.readbyqxmd.com/read/30073662/action-mechanisms-of-n-3-polyunsaturated-fatty-acids-on-the-oocyte-maturation-and-developmental-competence-potential-advantages-and-disadvantages
#13
REVIEW
Reza Zarezadeh, Amir Mehdizadeh, Jo L M R Leroy, Mohammad Nouri, Shabnam Fayezi, Masoud Darabi
Infertility is a growing problem worldwide. Currently, in vitro fertilization (IVF) is widely performed to treat infertility. However, a high percentage of IVF cycles fails, due to the poor developmental potential of the retrieved oocyte to generate viable embryos. Fatty acid content of the follicular microenvironment can affect oocyte maturation and the subsequent developmental competence. Saturated and monounsaturated fatty acids are mainly used by follicle components as primary energy sources whereas polyunsaturated fatty acids (PUFAs) play a wide range of roles...
August 2, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/30072087/il-5-in-follicular-fluid-as-a-negative-predictor-of-the-intracytoplasmic-sperm-injection-outcome
#14
Miaad Jabbar Sahib Alhilali, Abbas Parham, Armin Attaranzadeh, Malihe Amirian, Mohammad Azizzadeh
PURPOSE: To determine the prognostic value of intrafollicular concentrations of some cytokines from women undergoing ovarian stimulation in the outcome of intracytoplasmic sperm injection/embryo transfer (ICSI/ET) cycles. METHODS: A total of 80 patients were included in this study following ovarian stimulation and ICSI. Follicular fluids (FF) were collected at the day of oocyte retrieval. Ten cytokines including: tumor necrosis factor- alpha (TNF-α), interleukin (IL)-1β, IL-2, IL-4, IL-5, IL-6, CXCL8/IL-8, IL-10, granulocyte-macrophage colony stimulating factor (GM-CSF), and interferon gamma (IFN-γ) were measured using magnetic multiplex immunoassays...
July 30, 2018: Cytokine
https://www.readbyqxmd.com/read/30021634/effect-of-preconceptional-orlistat-treatment-on-in-vitro-fertilization-outcome-in-overweight-obese-women-study-protocol-for-a-randomized-controlled-trial
#15
Jing Li, Ze Wang, Daimin Wei, Hong Liu, Jiangtao Zhang, Jianfeng Wang, Yuhua Shi, Zi-Jiang Chen
BACKGROUND: Obese women have fewer oocytes retrieved, an increased cancelation rate, a higher miscarriage rate, and a lower live birth rate after assisted reproductive technology (ART) treatment compared with women with normal weight. Weight loss before ART treatment can significantly improve pregnancy rates and/or live births. An orlistat plus diet intervention could promote weight loss, but there is no evidence from randomized clinical trials evaluating the effect of orlistat preconceptional treatment on pregnancy outcome in overweight and obese women...
July 18, 2018: Trials
https://www.readbyqxmd.com/read/30021630/probabilistic-cost-effectiveness-analysis-of-controlled-ovarian-stimulation-with-recombinant-fsh-plus-recombinant-lh-vs-human-menopausal-gonadotropin-for-women-undergoing-ivf
#16
F S Mennini, A Marcellusi, R Viti, C Bini, A Carosso, A Revelli, C Benedetto
BACKGROUND: The association of recombinant FSH plus recombinant LH in 2:1 ratio may be used not only to induce ovulation in anovulatory women with hypogonadotropic hypogonadism but also to achieve multiple follicular developments in human IVF. The aim of this analysis was to estimate the cost-effectiveness of Controlled Ovarian Stimulation (COS) with recombinant FSH (rFSH) plus recombinant LH (rLH) in comparison with highly purified human menopausal gonadotropin (HP-hMG) in the woman undergoing in vitro fertilization (IVF) in Italy...
July 18, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/30016431/ovarian-response-is-associated-with-anogenital-distance-in-patients-undergoing-controlled-ovarian-stimulation-for-ivf
#17
F Fabregues, I González-Foruria, J Peñarrubia, F Carmona
STUDY QUESTION: Is the length of the anogenital distance (AGD) a biomarker of ovarian reserve and response to controlled ovarian stimulation (COS)? SUMMARY ANSWER: Shorter AGD is associated with presence of poor ovarian response. WHAT IS KNOWN ALREADY: Organ development during prenatal life is influenced by the prevailing intrauterine environment, and it has been suggested that nutritional, environmental and toxic factors could affect ovarian reserve set prenatally...
July 16, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30013427/effects-of-cyclophosphamide-administration-on-the-in-vitro-fertilization-of-mice
#18
Megumi Koike, Akiko Kanda, Kyoko Kido, Kaori Goto, Yoko Kumasako, Miyuki Nagaki, Eiko Otsu, Yasuyuki Araki, Yasuhisa Araki, Fumiko Kawabe, Yufuko Kai, Takafumi Utsunomiya
Purpose: To evaluate the oocyte fertilization ability and embryo growth after cyclophosphamide (CPA) treatment in mice. Methods: Mice were treated with CPA at different doses (0-800 mg/kg body weight). The oocytes then were retrieved and evaluated for their in vitro fertilization efficiency. Results: The average number of metaphase II (MII) oocytes significantly decreased by ≥400 mg/kg CPA administration. The fertilization rate also decreased in the group that was treated with ≥400 mg/kg CPA...
July 2018: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/30010882/diminished-ovarian-reserve-and-poor-response-to-stimulation-in-patients-38-years-old-a-quantitative-but-not-qualitative-reduction-in-performance
#19
S J Morin, G Patounakis, C R Juneau, S A Neal, R T Scott, E Seli
STUDY QUESTION: Do infertile women aged <38 years with quantitative evidence of diminished ovarian reserve and/or poor response to stimulation also exhibit poor oocyte quality as measured by blastulation rates, aneuploidy rates, and live birth rates? SUMMARY ANSWER: Young women with evidence of accelerated follicular depletion, either by precycle ovarian reserve testing or postcycle evidence of low oocyte yield, exhibit equivalent blastulation rates, aneuploidy rates and live birth rates per euploid embryo transfer as age-matched controls with normal precycle and postcycle parameters...
July 11, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30010519/the-role-of-propofol-on-mouse-oocyte-meiotic-maturation-and-early-embryo-development
#20
Xia-Guang Duan, Zai-Qing Huang, Chun-Guang Hao, Xiao-Jun Zhi, Xiao-Bing Qi, Ling Ren, Sheng-Hui Luan, Cheng-Guang Liang
SummaryPropofol is a intravenous anaesthetic most commonly used in ultrasound oocyte retrieval. We studied if the use of propofol had an effect on mouse oocyte maturation, pregnancy, childbirth and progeny and investigated the correlation between propofol side effects and reproductive performance in mice. There was no statistical difference in mating, pregnancy, childbirth, litter size, the number of stillbirths and survival between each group (P>0.05). Propofol also had no effect on polar body extrusion in oocyte maturation as well as on pronucleus formation and, subsequently, early embryo development (P>0...
July 16, 2018: Zygote: the Biology of Gametes and Early Embryos
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