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https://www.readbyqxmd.com/read/28640646/an-enzyme-linked-immunosorbent-assay-for-monoester-type-aconitic-alkaloids-and-its-application-in-the-pharmacokinetic-study-of-benzoylhypaconine-in-rats
#1
Can-Can Liu, Yun-Hui Xu, Shuai Yuan, Yu Xu, Mo-Li Hua
A new enzyme-linked immunosorbent assay (ELISA) method for quantitative determination of monoester-type aconitic alkaloids was developed. The antibodies derived from the immunogen of benzoylmesaconine (BM) could be electively affined to benzoylaconitine-type alkaloids with an ester bond (14-benzoyl-), especially to benzoylhypaconine (BH, 140.02% of cross-reactivity). The effective working range of BH was 1 ng/ml to 5 μg/ml; the lower limit of detection and the quantification were 0.35 and 0.97 ng/ml, respectively...
June 22, 2017: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/28637292/ten-year-real-life-effectiveness-of-coronary-artery-bypass-using-radial-artery-or-great-saphenous-vein-grafts-in-a-single-centre-chinese-hospital
#2
Yunpeng Zhu, Anqing Chen, Zhe Wang, Jun Liu, Junfeng Cai, Mi Zhou, Qiang Zhao
OBJECTIVES: Long-term effectiveness of coronary artery bypass grafting using radial artery (RA) or great saphenous vein (SVG) grafts as a second conduit was compared. METHODS: Patients received simple elective off-pump coronary artery bypass involving both the left internal thoracic artery (LITA) and the left anterior descending artery between January 1999 and December 2005 at Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China. RA graft patients ( n  = 147 LITA + RA and n  = 61 LITA + RA + SVG) were matched with SVG graft patients ( n  = 208 LITA + SVG)...
June 16, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28637051/teaching-transnasal-endoscopy-to-graduate-students-without-a-hospital-or-simulation-laboratory-pool-noodles-and-cadavers
#3
Shari Salzhauer Berkowitz
Purpose: This study reports on a training opportunity in endoscopy in which speech-language pathology graduate students use inanimate objects and cadavers. Best practices for transnasal endoscopy in vivo require a physician to be nearby, but many graduate programs do not have this access. Method: Endoscopy was offered as a graduate elective. Students (13 women) initially learned to manipulate the endoscope through the lumen of a swimming pool noodle that was embedded with trinkets...
June 20, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28636739/a-comparison-of-tonsillar-surface-swabbing-fine-needle-aspiration-core-sampling-and-dissected-tonsillar-core-biopsy-culture-in-children-with-recurrent-tonsillitis
#4
Saurav Sarkar, Abheek Sil, Soma Sarkar, Biswajit Sikder
In recurrent tonsillitis, the pathogenic bacteria are harbored in the tonsil core, and therefore cultures of superficial swab samples are not particularly accurate in identifying specific types of core bacteria. On the other hand, the results of fine-needle aspiration (FNA) cultures of core samples have been closely correlated with the findings of core cultures in excised tonsils, and both methods are far superior to surface swabbing. We conducted a prospective study to compare the accuracy of culture findings from tonsillar tissue obtained by surface swabbing, FNA sampling of the tonsil core in situ, and core sampling of the excised tonsil in children with recurrent tonsillitis...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28636506/incidence-and-predictors-of-atrial-fibrillation-after-coronary-artery-bypass-surgery-detection-by-event-loop-recorder-monitoring-from-a-contemporary-multicentre-cohort
#5
Zainab Abdel-Salam, Wail Nammas
Background Atrial fibrillation (AF) is a frequent complication after cardiac surgery. We explored the incidence and predictors of post-operative AF at 30-day follow-up in an unselected multi-centre cohort of patients undergoing elective coronary artery bypass grafting (CABG) in contemporary practice. Methods and results We enrolled 740 consecutive patients scheduled for elective CABG with or without valve surgery. Cardiac rhythm was continuously monitored for 15 days after surgery by an ambulatory event loop recorder...
March 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28636503/effects-of-instructional-physical-activity-courses-on-overall-physical-activity-and-mood-in-university-students
#6
James J Annesi, Kandice J Porter, Grant M Hill, Bernard D Goldfine
PURPOSE: The aim of this research was to assess the association between university-based instructional physical activity (PA) courses and changes in overall PA levels and negative mood and their interrelations. The study also sought to determine the amount of change in PA required to significantly improve mood in course enrollees. METHOD: Participants were university students initially completing PA below the level recommended for health who were either presently enrolled in an elective instructional PA course (treatment group, n = 52, 69% female) or not presently enrolled in such a course (comparison group, n = 32, 69% female)...
June 21, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/28636471/laparoscopic-colectomy-in-a-district-hospital-the-single-surgeon-can-be-safe
#7
A A Aikoye, A Khushal, C Parkin, T Bates
BACKGROUND: Several outcome measures have been identified for colorectal surgery and published in the literature. This study sought to compare outcomes of high volume laparoscopic colectomy by a single surgeon in a district hospital with outcomes from tertiary referral centres. METHODS: This was a retrospective review of elective laparoscopic colectomy by a single laparoscopic general surgeon in a district hospital over a 51-month period using a prospectively maintained database...
February 7, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28635485/letter
#8
Suzy
Why is it 'interesting' that three of the nurse MPs are Conservative (Election wins boost nurse numbers in the Commons, news, 14 June)?
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28635484/political-losses
#9
Stephanie Glanville
I am gutted Labour didn't win the election, as they promised to reintroduce the bursary. I put my nursing degree on hold for 16 months due to my daughter's illness. The new term begins in September, but I have lost my bursary and maintenance grant entitlement. I can no longer afford to do the course.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28635459/pay-must-be-overhauled-says-re-elected-nurse-mp
#10
Matthew Mckew
Nurses should be able to expect the same pay for doing the same job wherever they work, a re-elected nurse MP has said.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28634674/prognostic-impact-of-nutritional-status-assessed-by-the-controlling-nutritional-status-score-in-patients-with-stable-coronary-artery-disease-undergoing-percutaneous-coronary-intervention
#11
Hideki Wada, Tomotaka Dohi, Katsumi Miyauchi, Shinichiro Doi, Hirokazu Konishi, Ryo Naito, Shuta Tsuboi, Manabu Ogita, Takatoshi Kasai, Shinya Okazaki, Kikuo Isoda, Satoru Suwa, Hiroyuki Daida
BACKGROUND: Recently, malnutrition has been shown to be related to worse clinical outcomes in patients with heart failure. However, the association between nutritional status and clinical outcomes in patients with coronary artery disease (CAD) remains unclear. We investigated the prognostic value of malnutrition assessed by the Controlling Nutritional Status (CONUT; range 0-12, higher = worse, consisting of serum albumin, cholesterol and lymphocytes) score in patients with CAD. METHODS: The CONUT score was measured on admission in a total of 1987 patients with stable CAD who underwent elective percutaneous coronary intervention (PCI) between 2000 and 2011...
June 20, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28634502/impact-of-neurological-follow-up-on-early-hospital-readmission-rates-for-acute-ischemic-stroke
#12
Alexander Allen, Todd Barron, Ashley Mo, Richard Tangel, Ruth Linde, Rodney Grim, John Mingle, Ellen Deibert
INTRODUCTION: Despite advances in stroke care, readmission rates for patients with ischemic stroke remain high. Although factors such as age, diabetes, and continuous use of antiplatelet agents have been found to predict readmission rates, the impact of after-hospital care has not been examined. METHODS: The present study reviewed the charts of 416 patients with acute ischemic stroke and recorded stroke-related comorbidities, neurology follow-up within 21 days, readmission at 0 to 30 days, readmission at 31 to 90 days, and any reasons for readmission...
July 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28634135/outcomes-and-role-of-urgent-endoscopy-in-high-risk-patients-with-acute-nonvariceal-gastrointestinal-bleeding
#13
Soo-Han Cho, Yoon-Seon Lee, Youn-Jung Kim, Chang Hwan Sohn, Shin Ahn, Dong-Woo Seo, Won Young Kim, Jae Ho Lee, Kyoung Soo Lim
BACKGROUND & AIMS: We investigated clinical outcomes in high-risk patients with acute nonvariceal upper gastrointestinal bleeding (UGIB), and determined if urgent endoscopy is effective. METHODS: Consecutive patients with Glasgow-Blatchford score >7 who underwent endoscopy for acute nonvariceal UGIB at the emergency department from January 1, 2005, to December 31, 2014, were included. Urgent (<6 h) and elective (6-48 h) endoscopies were defined according to the time to endoscopy after the initial presentation...
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28633644/risk-factors-for-pulmonary-complications-after-hepatic-resection-role-of-intraoperative-hemodynamic-instability-and-hepatic-ischemia
#14
Victoria Lepere, Antoine Vanier, Yann Loncar, Louis Lemoine, Jean Christophe Vaillant, Antoine Monsel, Eric Savier, Pierre Coriat, Daniel Eyraud
BACKGROUND: Postoperative operative pulmonary complications (PPCs) after hepatic surgery are associated with increased length of hospital stays. Intraoperative blood transfusion, extensive resection and different comorbidities have been identified. Other parameters, like time of hepatic ischemia, have neither been clinically studied, though experimental studies show that hepatic ischemia can provide lung injury. The objective of this study was to determinate the risk factors of postoperative pulmonary complications (PPCs) after hepatic resection within 7 postoperative days...
June 20, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28633519/changes-in-abdominal-aortic-aneurysm-epidemiology
#15
Fredrik Lilja, Anders Wanhainen, Kevin Mani
INTRODUCTION: The epidemiology and treatment of abdominal aortic aneurysms (AAA) has changed over the past 30 years. EVIDENCE ACQUISITION: This review aims to give the reader an overview of these changes and current trends in AAA epidemiology, management and outcome. EVIDENCE SYNTHESIS: In the past decades there have been three changes in AAA management and epidemiology: a) introduction of endovascular aortic repair (EVAR), b) population screening and c) a markedly reduced prevalence of the disease...
June 20, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28633411/surgeon-level-variability-in-outcomes-cost-and-comorbidity-adjusted-cost-for-elective-lumbar-decompression-and-fusion
#16
Silky Chotai, Ahilan Sivaganesan, John A Sielatycki, Kristin R Archer, Richard Call, Matthew J McGirt, Clinton J Devin
BACKGROUND: The costs and outcomes following degenerative spine surgery may vary from surgeon to surgeon. Patient factors such as comorbidities may increase the health care cost. These variations are not well studied. OBJECTIVE: To understand the variation in outcomes, costs, and comorbidity-adjusted cost for surgeons performing lumbar laminectomy and fusions surgery. METHODS: A total of 752 patients undergoing laminectomy and fusion, performed by 7 surgeons, were analyzed...
June 14, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28633374/cohort-study-of-preoperative-blood-pressure-and-risk-of-30-day-mortality-after-elective-non-cardiac-surgery
#17
S Venkatesan, P R Myles, H J Manning, A M Mozid, C Andersson, M E Jørgensen, J G Hardman, S R Moonesinghe, P Foex, M Mythen, M P W Grocott, R D Sanders
Background: Preoperative blood pressure (BP) thresholds associated with increased postoperative mortality remain unclear. We investigated the relationship between preoperative BP and 30-day mortality after elective non-cardiac surgery. Methods: We performed a cohort study of primary care data from the UK Clinical Practice Research Datalink (2004-13). Parsimonious and fully adjusted multivariable logistic regression models, including restricted cubic splines for numerical systolic and diastolic BP, for 30-day mortality were constructed...
June 15, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28633075/elective-unilateral-nodal-irradiation-in-head-and-neck-squamous-cell-carcinoma-a-paradigm-shift
#18
A Al-Mamgani, M Verheij, M W M van den Brekel
There is a long-standing convention to irradiate the great majority of head and neck squamous cell carcinoma (HNSCC) electively to both sides of the neck, to reduce the theoretically increased risk of contralateral regional failure (cRF). With the currently available diagnostic imaging techniques this treatment paradigm means, in our opinion, an overtreatment in considerable proportion of these patients. From all the published studies (n = 11, with 1116 patients treated in total), the incidence of cRF in patients with oropharyngeal cancer treated to one side of the neck is 2...
June 17, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28632602/visits-to-the-emergency-department-after-joint-replacement-commentary-on-an-article-by-micaela-a-finnegan-ba-et-al-emergency-department-visits-following-elective-total-hip-and-knee-replacement-surgery-identifying-gaps-in-continuity-of-care
#19
https://www.readbyqxmd.com/read/28632589/emergency-department-visits-following-elective-total-hip-and-knee-replacement-surgery-identifying-gaps-in-continuity-of-care
#20
Micaela A Finnegan, Robyn Shaffer, Austin Remington, Jereen Kwong, Catherine Curtin, Tina Hernandez-Boussard
BACKGROUND: Major joint replacement surgical procedures are common, elective procedures with a care episode that includes both inpatient readmissions and postoperative emergency department (ED) visits. Inpatient readmissions are well studied; however, to our knowledge, little is known about ED visits following these procedures. We sought to characterize 30-day ED visits following a major joint replacement surgical procedure. METHODS: We used administrative records from California, Florida, and New York, from 2010 through 2012, to identify adults undergoing total knee and hip arthroplasty...
June 21, 2017: Journal of Bone and Joint Surgery. American Volume
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