Read by QxMD icon Read


Luana Viana de Oliveira, Nailú Angélica Sinicato, Simone Appenzeller, Carlos Ewerton Maia Rodrigues, Jozélio Freire de Carvalho
The objective of this study was to evaluate the sleep quality, the presence of sleep disorders in patients with primary antiphospholipid syndrome (pAPS), and their possible clinical and laboratory associations. This was a cross-sectional study of 40 consecutive pAPS patients and 211 healthy age- and sex-matched controls. Demographic and clinical data, drug use, and antiphospholipid antibodies were evaluated. Sleep was evaluated using the Pittsburgh Sleep Quality Index (PSQI). pAPS patients had significantly worse sleep quality than healthy controls...
October 19, 2018: Clinical Rheumatology
Renate Deinzer, Stefanie Ebel, Helen Blättermann, Ulrike Weik, Jutta Margraf-Stiksrud
BACKGROUND: Weaknesses in toothbrushing performance can be seen when young adults are instructed to perform habitual toothbrushing. Nothing is known about toothbrushing behavior when instructed to perform to the best abilities. The present study analyzes such behavior and compares it to habitual behavior. METHODS: A random sample of N = 98 young adults born in 1995 was examined in 2014/2015.They were asked to perform oral hygiene to the best of their abilities in front of a camera...
October 19, 2018: BMC Oral Health
T M Houslay, R L Earley, A J Young, A J Wilson
The vertebrate stress response enables individuals to react to and cope with environmental challenges. A crucial aspect of the stress response is the elevation of circulating glucocorticoids. However, continued activation of the stress response under repeated exposure to stressors can be damaging to fitness. Under certain circumstances it may therefore be adaptive to habituate to repeated exposures to a particular stressor by reducing the magnitude of any associated release of glucocorticoids. Here, we investigate whether Trinidadian guppies (Poecilia reticulata) habituate to repeated exposure to a mild stressor, using a waterborne hormone sampling approach that has previously been shown to elicit a stress response in small fish...
October 16, 2018: General and Comparative Endocrinology
Jeanette M Bennett, Nicolas Rohleder, Joachim P Sturmberg
BACKGROUND: Resilience in the face of adversity is a human experience that leads to better health, both mentally and physically. We briefly review its historical origins rooted in ecological biology and its adoption into health care. Resilience is the common response to adversity or potential traumatic events. Individual differences in emotion regulation and coping skills as well as social capital and one's physical environment influence a person's ability to achieve resilience. PROPOSED MECHANISM: One potential biopsychosocial measure of resilience includes stress habituation to repeated stress as demonstrated in the laboratory, possibly providing a tool to observe mastery of resilience training in the clinic...
October 18, 2018: Journal of Evaluation in Clinical Practice
Stephen Malloch, Colwyn Trevarthen
Music is at the centre of what it means to be human - it is the sounds of human bodies and minds moving in creative, story-making ways. We argue that music comes from the way in which knowing bodies (Merleau-Ponty) prospectively explore the environment using habitual 'patterns of action,' which we have identified as our innate 'communicative musicality.' To support our argument, we present short case studies of infant interactions using micro analyses of video and audio recordings to show the timings and shapes of intersubjective vocalizations and body movements of adult and child while they improvise shared narratives of meaning...
2018: Frontiers in Psychology
Akbar Shabir, Andy Hooton, Jason Tallis, Matthew F Higgins
Caffeine (CAF) is widely consumed across sport and exercise for its reputed ergogenic properties, including central nervous stimulation and enhanced muscular force development. However, expectancy and the related psychological permutations that are associated with oral CAF ingestion are generally not considered in most experimental designs and these could be important in understanding if/how CAF elicits an ergogenic effect. The present paper reviews 17 intervention studies across sport, exercise, and cognitive performance...
October 17, 2018: Nutrients
Anastasios-Georgios Konstas, Andreas Katsanos, Georgios P Athanasopoulos, Irini C Voudouragkaki, Evangelia S Panagiotou, Eirini Pagkalidou, Anna-Bettina Haidich, Dimitrios A Giannoulis, Eleni Spathi, Theodoros Giannopoulos, L Jay Katz
BACKGROUND: Ideal dosing for the preservative-free (PF) tafluprost/timolol fixed combination (TTFC) remains to be elucidated. RESEARCH DESIGN AND METHODS: This study was a prospective, observer-masked, placebo-controlled, crossover, comparison in 42 consecutive open-angle glaucoma patients whose intraocular pressure (IOP) was insufficiently controlled with preserved latanoprost monotherapy (mean 24-h IOP >20 mmHg). Patients were randomized to either morning (08:00) or evening (20:00) PF TTFC for 3 months and then crossed over...
October 17, 2018: Expert Opinion on Pharmacotherapy
Utpal K Prodhan, Amber M Milan, Eric B Thorstensen, Matthew P G Barnett, Ralph A H Stewart, Jocelyn R Benatar, David Cameron-Smith
Dairy, as a major component of a high protein diet, is a critical dietary source of branched chain amino acids (BCAA), which are biomarkers of health and diseases. While BCAA are known to be key stimulators of protein synthesis, elevated circulatory BCAA is an independent risk factor for type 2 diabetes mellitus. This study examined the impact of altered dairy intake on plasma BCAA and their potential relationship to insulin sensitivity. Healthy adults ( n = 102) were randomized to receive dietary advice to reduce, maintain, or increase habitual dairy intake for 1 month...
October 15, 2018: Nutrients
Kyle L Timmerman, Kevin D Ballard, Gabrielle A Volk, Michael A Deal, Adam J Meisler, Jenna M Karrow, Alex P Good, Sandy T Reynolds
This study determined if varying physical activity (PA) the day prior to an oral glucose tolerance test (OGTT) differentially influenced postprandial glucose and insulin kinetics. Fifteen healthy, young adults participated in three OGTT trials the morning after performing 50% (LOW), 100% (HABITUAL), or 150% (HIGH) of their habitual PA (determined by 7-day pedometry). Trials were randomized and separated by at least 1-wk. For each OGTT trial, blood glucose and insulin were measured after an overnight fast and at 30-min intervals for 2 h following ingestion of the glucose beverage...
October 16, 2018: International Journal of Sports Medicine
Hitomi Okubo, Kentaro Murakami, Hiroki Inagaki, Yasuyuki Gondo, Kazunori Ikebe, Kei Kamide, Yukie Masui, Yasumichi Arai, Tatsuro Ishizaki, Satoshi Sasaki, Takeshi Nakagawa, Mai Kabayama, Ken Sugimoto, Hiromi Rakugi, Yoshinobu Maed, Madoka Ogawa, Yoshiko Lily Ishioka, Chisato Inomatae, Taiji Ogawa, Ken-Ichi Matsuda, Hirochika Ryuno, Ryosuke Oguro, Koichi Yamamoto, Yasushi Takeya, Yoichi Takami, Norihisa Ito
BACKGROUND: There is increasing evidence of causal links between poor mastication and cognitive impairment, but possible effects of dietary hardness, which clearly affects mastication, on cognitive function is unknown. OBJECTIVE: We investigated the hypothesis that hardness of the habitual diet would be associated with cognitive function among older Japanese adults. METHODS: The subjects of this cross-sectional study were 635 Japanese community-dwelling people aged 69-71 years...
October 16, 2018: Journal of Oral Rehabilitation
Virginia Carter Leno, Susie Chandler, Pippa White, Isabel Yorke, Tony Charman, Andrew Pickles, Emily Simonoff
Background: Many young people with autism spectrum disorder (ASD) experience emotional and behavioural problems. However, the causes of these co-occurring difficulties are not well understood. Perceptual processing atypicalities are also often reported in individuals with ASD, but how these relate to co-occurring emotional and behavioural problems remains unclear, and few studies have used objective measurement of perceptual processing. Methods: Event-related potentials (ERPs) were recorded in response to both standard and deviant stimuli (which varied in pitch) in an auditory oddball paradigm in adolescents (mean age of 13...
2018: Molecular Autism
Wanxia Fang, Xiujuan Qu, Jing Shi, Heming Li, Xiaoyu Guo, Xin Wu, Yunpeng Liu, Zhi Li
BACKGROUND/OBJECTIVES: Conflicting results have been reported on the association of cruciferous vegetable intake and colorectal cancer risk. This study aimed to clarify the relationship of cruciferous vegetables and colorectal cancer among individuals in Northeast China, where large amounts of cruciferous vegetables are consumed habitually. SUBJECTS/METHODS: We conducted a hospital-based case-control study in the First Hospital of China Medical University, the Shengjing Hospital of China Medical University and the First Hospital of Dalian Medical University from 2009 to 2011...
October 15, 2018: European Journal of Clinical Nutrition
Mirko Magnone, Giovanna Leoncini, Tiziana Vigliarolo, Laura Emionite, Laura Sturla, Elena Zocchi, Giovanni Murialdo
We tested the effect of chronic low-dose abscisic acid (ABA), a phytohormone-regulating human glucose tolerance, on the metabolic parameters that are dysregulated in prediabetes and metabolic syndrome (MS).Ten healthy subjects received 1 µg ABA/Kg body weight (BW)/day as an ABA-rich food supplement: (i) the glycemia profile after a carbohydrate-rich meal, with or without supplement, was compared; (ii) fasting blood glucose (FBG), glycated hemoglobin (HbA1c), total cholesterol (TC), and body mass index (BMI) after 75 days of daily supplementation of a habitual Mediterranean diet were compared with starting values...
October 12, 2018: Nutrients
L Duart-Castells, R López-Arnau, M Buenrostro-Jáuregui, P Muñoz-Villegas, O Valverde, J Camarasa, D Pubill, E Escubedo
3,4-methylenedioxypyrovalerone (MDPV) is a synthetic cathinone with cocaine-like properties. In a previous work, we exposed adolescent mice to MDPV, finding sensitization to cocaine effects, and a higher vulnerability to cocaine abuse in adulthood. Here we sought to determine if such MDPV schedule induces additional behavioral-neuronal changes that could explain such results. After MDPV treatment (1.5 mg kg-1 , twice daily, 7 days), mice were behaviorally tested. Also, we investigated protein changes in various brain regions...
October 12, 2018: Neuropharmacology
Isabelle Brocas, Juan D Carrillo
We propose a theoretical model that places attention at the center of mental time travel (MTT) ability. This theory predicts that attention promotes a memory-based process that encodes memories of unexpected events, facilitates accurate recollection of information of such events during MTT, and optimizes subsequent decision-making. This process coexists with a habitual process that governs all other events and treats them equally. Our theory demonstrates that the memory-based process is useful when the environment features novel experiences that are likely to be relevant in future decision-making, hence worth remembering accurately...
2018: Frontiers in Neuroscience
Dolly Al Koborssy, Brigitte Palouzier-Paulignan, Vincent Canova, Marc Thevenet, Debra Ann Fadool, Andrée Karyn Julliard
Olfaction is one of the major sensory modalities that regulates food consumption and is in turn regulated by the feeding state. Given that the olfactory bulb has been shown to be a metabolic sensor, we explored whether the anterior piriform cortex (aPCtx)-a higher olfactory cortical processing area-had the same capacity. Using immunocytochemical approaches, we report the localization of Kv1.3 channel, glucose transporter type 4, and the insulin receptor in the lateral olfactory tract and Layers II and III of the aPCtx...
October 13, 2018: Brain Structure & Function
Aileen McGonigal, Stanislas Lagarde, Agnès Trébuchon-Dafonseca, Nicolas Roehri, Fabrice Bartolomei
OBJECTIVES: The objective of the study was to describe electroclinical patterns in habitual seizures with motor semiology at onset, triggered by diagnostic stimulation, in patients undergoing presurgical evaluation using stereoelectroencephalography (SEEG). METHODS: Seizure semiology, stimulation parameters, electroclinical data, and anatomical localization were evaluated in stimulated and spontaneous seizures. RESULTS: From 120 habitual seizures triggered by 50-Hz train bipolar stimulation during SEEG, 20 presented initial motor semiology (elementary motor signs, complex motor behavior, or both)...
October 11, 2018: Epilepsy & Behavior: E&B
Mats Hallgren, Thi-Thuy-Dung Nguyen, Andreas Lundin, Davy Vancampfort, Brendon Stubbs, Felipe Schuch, Rino Bellocco, Ylva Trolle Lagerros
Regular physical activity (PA) appears to protect against the emergence of depression, but prospective studies linked to clinician diagnoses of major depressive disorder (MDD) remain scarce. It is also unclear whether PA levels recommended for general health are prospectively related to depression onset. We explored these relationships in a cohort of adults followed over 13 years. In total, 43,863 Swedish adults were surveyed in 1997 and responses linked to clinician-diagnosed MDD obtained from specialist medical registers until 2010...
October 11, 2018: Preventive Medicine
Pedro Espitia-Pérez, Suelen Marin Albino, Lyda Espitia-Pérez, Hugo Brango, Helen da Rosa, Alexandre Kleber Silveira, Diogo Pompéu Moraes, Camila Cerveira, Moara Mingori, Camila Tiefensee Ribeiro, Daniel Pens Gelain, Carlos Eduardo Schnorr, José Cláudio Fonseca Moreira
Fish consumption and ubiquitous methylmercury (MeHg) exposure represent a public health problem globally. Micronutrients presented in fish affects MeHg uptake/distribution. Vitamin A (VitA), another fish micronutrient is used in nutritional supplementation, especially during pregnancy. However, there is no information about the health effects arising from their combined exposure. The present study aimed to examine the effects of both MeHg and retinyl palmitate administered to pregnant and lactating rats. Thirty Wistar female rats were orally supplemented with MeHg (0,5 mg/Kg/day) and retinyl palmitate (7500 µg RAE1 /Kg/day), either individually or in combination from the gestational day 0 to weaning...
October 11, 2018: Neurotoxicology
Elizabeth S Stevens, Evelyn Behar, Alexander A Jendrusina
Cognitive bias modification for interpretation (CBM-I) is a promising treatment modality for social anxiety disorder, but effect sizes are relatively small across investigations (Hallion & Ruscio, 2011). Additionally, the extent to which CBM-I impacts other cognitive, emotional, and behavioral outcomes is unclear. This study investigated whether two empirically supported treatment components for anxiety disorders, imaginal exposure (IE) and relaxation, augment the effects of CBM-I and increase the extent to which the effects of CBM-I generalize to behavioral and affective outcomes...
November 2018: Behavior Therapy
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"