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https://www.readbyqxmd.com/read/30481620/minimally-invasive-management-of-spontaneous-supratentorial-intracerebral-lobar-hemorrhages-by-a-home-made-endoscopic-strategy-the-evangelic-doctrine-of-venite-ad-me-allied-to-the-legacy-of-king-leonida
#1
Nicola Alberio, Salvatore Cicero, Domenico Gerardo Iacopino, Giuseppe Roberto Giammalva, Massimiliano Visocchi, Alessandro Olivi, Natale Francaviglia, Roberto Battaglia, Angelo Spitaleri, Rita Lipani, Luca Ruggeri, Raffaele Alessandrello, Alessandro Cinquemani, Rosario Maugeri
BACKGROUND: While the incidence of intracerebral haemorrhage (ICH) appear to be increasing over the year, its prognosis still remains dismal . Although no consensus about the management of ICH has be found, minimal invasive surgery should limit - when not avoid - the intra operative parenchymal damage. At this regard, we present a novel modified "home made" approach, aimed to shorten the operative time and minimize the corticectomy and brain manipulation, with our clinical series...
November 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30473440/the-pediatric-guideline-adherence-and-outcomes-pegasus-programme-in-severe-traumatic-brain-injury-a-single-centre-hybrid-implementation-and-effectiveness-study
#2
Monica S Vavilala, Mary A King, Jen-Ting Yang, Scott L Erickson, Brianna Mills, Rosemary M Grant, Carolyn Blayney, Qian Qiu, Randall M Chesnut, Kenneth M Jaffe, Bryan J Weiner, Brian D Johnston
BACKGROUND: As far as we know, there are no tested in-hospital care programmes for paediatric traumatic brain injury. We aimed to assess implementation and effectiveness of the Pediatric Guideline Adherence and Outcomes (PEGASUS) programme in children with severe traumatic brain injury. METHODS: We did a prospective hybrid implementation and effectiveness study at the Harborview Medical Center (Seattle, WA, USA). We included children (aged <18 years) with traumatic brain injury (trauma mechanism and image findings)...
November 22, 2018: The lancet child & adolescent health
https://www.readbyqxmd.com/read/30410918/extracellular-vesicles-secreted-by-hypoxic-ac10-cardiomyocytes-modulate-fibroblast-cell-motility
#3
Imelda Ontoria-Oviedo, Akaitz Dorronsoro, Rafael Sánchez, Maria Ciria, Marta Gómez-Ferrer, Marc Buigues, Elena Grueso, Sandra Tejedor, Francisco García-García, Hernán González-King, Nahuel A Garcia, Esteban Peiró-Molina, Pilar Sepúlveda
Extracellular vesicles (EVs) are small membrane vesicles secreted by most cell types with important roles in cell-to-cell communication. To assess their relevance in the context of heart ischemia, EVs isolated from the AC10 ventricular cardiomyocyte cell line (CM-EVs), exposed to normoxia (Nx) or hypoxia (Hx), were incubated with fibroblasts (Fb) and endothelial cells (EC). CM-EVs were studied using electron microscopy, nanoparticle tracking analysis (NTA), western blotting and proteomic analysis. Results showed that EVs had a strong preference to be internalized by EC over fibroblasts, suggesting an active exosome-based communication mechanism between CM and EC in the heart...
2018: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30339709/pneumococcal-colonization-among-tracheostomy-tube-dependent-children
#4
Guliz Erdem, Anirudh K Singh, Anthony J Brusnahan, Amber N Moore, William J Barson, Amy Leber, Jorge E Vidal, Serkan Atici, Samantha J King
Streptococcus pneumoniae colonization is a precursor to pneumococcal disease. Although children with a tracheostomy have an increased risk of pneumococcal pneumonia, the pneumococci colonizing their lower airways remain largely uncharacterized. We sought to compare lower respiratory tract isolates colonizing tracheostomy patients and a convenience sample of isolates from individuals intubated for acute conditions. We collected pneumococcal isolates from the lower respiratory tract of 27 patients with a tracheostomy and 42 patients intubated for acute conditions...
2018: PloS One
https://www.readbyqxmd.com/read/30276153/application-of-portable-digital-radiography-for-dental-investigations-of-ancient-egyptian-mummies-during-archaeological-excavations-evaluation-and-discussion-of-the-advantages-and-limitations-of-different-approaches-and-projections
#5
Roger Seiler, Patrick Eppenberger, Frank Rühli
Purpose: In the age of X-ray computed tomography (CT) and digital volume tomography (DVT), with their outstanding post-processing capabilities, indications for planar radiography for the study of the dentition of ancient Egyptian mummies may easily be overlooked. In this article, the advantages and limitations of different approaches and projections are discussed for planar oral and maxillofacial radiography using portable digital X-ray equipment during archaeological excavations. Furthermore, recommendations are provided regarding projections and sample positioning in this context...
September 2018: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/30236548/caregiver-perceptions-about-their-decision-to-pursue-tracheostomy-for-children-with-medical-complexity
#6
Savithri Nageswaran, Shannon L Golden, W Adam Gower, Nancy M P King
OBJECTIVE: To describe the perceptions of caregivers of children with medical complexity (CMC) about their decision to pursue tracheostomy for their children, in particular the satisfaction with their decision. STUDY DESIGN: In this qualitative study conducted in western North Carolina between 2013 and 2014, we interviewed 56 caregivers of 41 CMC who had received tracheostomies in the past 5 years. Three of the CMC were deceased at the time of the interview; 8 were decannulated...
December 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/30227894/significant-bleeding-from-meckel-s-diverticulum-after-blunt-abdominal-trauma-a-case-report
#7
Sharfuddin Chowdhury, Abdullah Maher Alenazi, Yam Alwi Alharthi
BACKGROUND: Meckel's diverticulum, with an incidence of 2%, is the most common congenital anomaly in the gastrointestinal tract. Its main complications are perforation, obstruction, and bleeding. A few studies have reported that blunt abdominal trauma may result in perforation or obstruction to Meckel's diverticulum. However, reports of significant major intestinal bleeding from Meckel's diverticulum as a complication of blunt abdominal trauma is rare. This paper present what we believe to be the first reported case of significant intestinal bleeding from a Meckel's diverticulum following blunt abdominal trauma...
September 19, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/30224595/constipation-in-the-elderly-in-a-japanese-long-term-medical-facility-an-ultrasonographic-investigation
#8
Koichi Yabunaka, Gojiro Nakagami, Keiko Tabata, Junko Sugama, Masaru Matsumoto, Yoshifumi Kido, Terumi Iuchi, Hiromi Sanada
This study aims to assess the fecal retention in elderly patients using colonic ultrasonography (US) in Japanese long-term care facility and determine the correlation between nutrition management methods and the fecal retention by US. This cross-sectional, single-center study was conducted in a long-term care facility in Japan. Patients with chronic constipation fulfilled the Rome III criteria for the diagnosis of functional constipation. US was performed on constipation patients with 4-day fecal retention before starting the standard management of constipation...
2018: Drug Discoveries & Therapeutics
https://www.readbyqxmd.com/read/30199088/-i-wouldn-t-ever-want-it-a-qualitative-evaluation-of-patient-and-caregiver-perceptions-toward-enteral-tube-feeding-in-hip-fracture-inpatients
#9
Patricia C King, Sally E Barrimore, Ranjeev C Pulle, Jack J Bell
BACKGROUND: One in 2 hip fracture inpatients are malnourished on admission to hospital, with many experiencing nutrition decline during their length of stay. Despite this, enteral tube feeding (ETF) is rarely used in this population. As patient/caregiver viewpoints regarding the utility of ETF remain unclear, this study explored the perceptions of hip fracture inpatients and caregivers toward ETF use to assist recovery. METHODS: An inductive qualitative research project was conducted within a tertiary hospital orthogeriatric ward...
September 10, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/30171266/predictors-of-extended-length-of-hospital-stay-following-surgical-repair-of-congenital-heart-diseases
#10
Ahmad Saeed Azhar, Hasan Mohamed Aljefri
The purpose of this study is to evaluate post-operative length of stay (LOS) following surgical repair of congenital heart defects (CHD) and to investigate baseline pre-operative factors and predictors of post-operative LOS (pLOS). Retrospective chart review of all cases of corrective surgery for CHD performed at the Pediatric Cardiology Unit, King Abdulaziz University Hospital, Jeddah during January 2013-December 2016. Baseline demographics, clinical factors, pre-operative, intra-operative, post-operative cardiac and extra-cardiac complications were analyzed as independent factors of pLOS using stepwise linear regression...
December 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/30108392/role-of-melatonin-in-management-of-hypoxic-ischaemic-encephalopathy-in-newborns-a-randomized-control-trial
#11
Qazi Mumtaz Ahmad, Akmal Laeeq Chishti, Nayyab Waseem
OBJECTIVE: To find out the effect of melatonin as adjunct therapy on outcome of admitted newborns presenting with hypoxic ischaemic encephalopathy. METHODS: This randomized controlled trial was conducted at King Edward Medical University, Lahore, Pakistan, from October 2016 to March 2017, and comprised newborns with gestational age of 34 weeks or higher who fulfilled the definition of hypoxic ischaemic encephalopathy and presented within 12 hours of birth. The severity of hypoxic ischaemic encephalopathy was assessed by Thompson score...
August 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/30038832/short-term-effects-of-trigger-point-dry-needling-on-pain-and-disability-in-subjects-with-patellofemoral-pain-syndrome
#12
Thomas G Sutlive, Andrew Golden, Kristin King, William B Morris, John E Morrison, Josef H Moore, Shane Koppenhaver
Background: Patellofemoral pain syndrome (PFPS) is a prevalent knee disorder. A novel yet increasingly popular treatment for PFPS is trigger point dry needling (DN). Purpose: The purpose of this study was to determine if DN is more effective at reducing pain and disability than a sham treatment in individuals with PFPS. Study design: Randomized trial. Materials/Methods: Sixty military health care beneficiaries (36 males) with a clinical diagnosis of PFPS were recruited and completed the study...
June 2018: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/30006929/evaluation-of-a-novel-cricothyroidotomy-introducer-in-a-simulated-obese-porcine-model-a-randomised-crossover-comparison-with-scalpel-cricothyroidotomy
#13
C Yeow, L Greaney, C Foy, W King, B Patel
The Difficult Airway Society 2015 guidelines for management of unanticipated difficulties in tracheal intubation in adults have generated much discussion regarding Plan D: emergency front-of-neck access with a scalpel-bougie cricothyroidotomy technique. There is concern that this technique may not provide an adequate pathway for the bougie and subsequently the tracheal tube, especially in obese patients with deeper airway structures. This could lead to the formation of a false passage, trauma and failure. A novel cricothyroidotomy introducer, 8 mm wide and 170 mm long, with a sharp leading edge and guiding channel to pass a bougie into the trachea, has been designed to complement the scalpel cricothyroidotomy technique...
October 2018: Anaesthesia
https://www.readbyqxmd.com/read/29931087/non-conventional-utilization-of-the-aintree-intubating-catheter-to-facilitate-exchange-between-three-supraglottic-airways-and-an-endotracheal-tube-a-cadaveric-trial
#14
Nicole T Lopez, Sean K McCoy, Christine Carroll, Ellen Jones, Joel A Miller
Background: Two studies by Bledsoe et al and Anand et al reported limited efficacy of the Supraglottic Airway Laryngeal Tube (SALT), which is a supraglottic airway (SGA) specifically designed for blind endotracheal intubation. Miller et al reported a 50% success rate using an Eschmann introducer as an adjunct for blind airway exchange via the laryngeal mask airway (LMA) classic. Another study by Ueki et al found that endotracheal tube (ETT) intubation was faster and less damaging to the airway when the Aintree intubating catheter was used in conjunction with a fiberoptic bronchoscope...
June 19, 2018: Military Medicine
https://www.readbyqxmd.com/read/29889963/are-the-king-lts-laryngeal-tube-and-the-ambu-auraonce-laryngeal-mask-useful-airway-adjuncts-for-military-medics
#15
Danny Regner, Peter Frykholm
BACKGROUND: Airway management is a critical skill that may be essential in the battlefield. The aim of this study was to determine if combat life savers and medics with no or limited clinical experience could provide airway control using the disposable laryngeal suction tube (LTS-D) and the Ambu® AuraOnce ™ disposable laryngeal mask (LMA). METHODS: Eight military medics with limited clinical experience and no airway management experience secured the airway on 19 intrahospital anesthetized patients using the LTS-D and the LMA...
December 0: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/29714527/comparison-of-the-force-required-for-dislodgement-between-secured-and-unsecured-airways
#16
Curtis Davenport, Christian Martin-Gill, Henry E Wang, James Mayrose, Jestin N Carlson
INTRODUCTION: Airway device placement and maintenance are of utmost importance when managing critically ill patients. The best method to secure airway devices is currently unknown. STUDY OBJECTIVE: We sought to determine the force required to dislodge 4 types of airways with and without airway securing devices. METHODS: We performed a prospective study using 4 commonly used airway devices (endotracheal tube [ETT], laryngeal mask airway [LMA], King laryngeal tube [King], and iGel) performed on 5 different mannequin models...
November 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29666693/removal-of-nasogastric-tube-accidentally-stitched-to-roux-en-y-oesophagojejunostomy-following-a-radical-gastrectomy-for-stomach-cancer-case-report-and-review-of-the-literature
#17
REVIEW
Ayman Z Azzam, Kareem A Azzam, Tarek Amin
Nasogastric tubes (NGTs) are important for feeding, stenting and decompression after gastrointestinal surgeries, particularly in the upper gastrointestinal tract. Resistance in the removal of a NGT is a rare surgical complication and may be due to a knot in the tube or a stitch anchoring the tube to an anastomosis . We report a 41-year-old male patient who was admitted to the King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia, in 2015 with stomach cancer. He underwent a radical total gastrectomy with a Roux-en-Y oesophagojejunostomy...
February 2018: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29602257/neonatal-oesophageal-perforation-the-role-for-non-operative-management
#18
Kate Hodgson, Andrea Togo, Aideen M Moore, Amanda Moody, Sebastian K King, Augusto Zani
AIM: Isolated oesophageal perforation in neonates is a rare but potentially life-threatening condition. Although management has historically been operative, conservative management (antibiotics, bowel rest, parenteral nutrition) is now more routinely used. The aim of this study was to evaluate the management of this condition in two large neonatal surgical centres. METHODS: A retrospective cohort study was conducted for neonates admitted to The Hospital for Sick Children (Toronto, Canada) or The Royal Children's Hospital (Melbourne, Australia) with a diagnosis of oesophageal perforation, from 2006 to 2016...
August 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29430820/controlling-the-diameters-of-nanotubes-self-assembled-from-designed-peptide-bolaphiles
#19
Yurong Zhao, Wei Yang, Dong Wang, Jiqian Wang, Zongyi Li, Xuzhi Hu, Stephen King, Sarah Rogers, Jian R Lu, Hai Xu
Controlling the diameters of nanotubes represents a major challenge in nanostructures self-assembled from templating molecules. Here, two series of bolaform hexapeptides are designed, with Set I consisting of Ac-KI4 K-NH2 , Ac-KI3 NleK-NH2 , Ac-KI3 LK-NH2 and Ac-KI3 TleK-NH2 , and Set II consisting of Ac-KI3 VK-NH2 , Ac-KI2 V2 K-NH2 , Ac-KIV3 K-NH2 and Ac-KV4 K-NH2 . In Set I, substitution for Ile in the C-terminal alters its side-chain branching, but the hydrophobicity is retained. In Set II, the substitution of Val for Ile leads to the decrease of hydrophobicity, but the side-chain β-branching is retained...
March 2018: Small
https://www.readbyqxmd.com/read/29416456/evaluation-of-safety-and-efficacy-of-regional-anesthesia-compared-with-general-anesthesia-in-thoracoscopic-lung-biopsy-procedure-on-patient-with-idiopathic-pulmonary-fibrosis
#20
Waseem M Hajjar, Sami A Al-Nassar, Ghaida S Al-Sugair, Alaa Al-Oqail, Shahd Al-Mansour, Rand Al-Haweel, Adnan W Hajjar
Background: Interstitial lung diseases are diseases that need histology diagnosis or obtaining a lung biopsy to establish the diagnosis. Surgical biopsies are performed usually using the thoracoscopy technique under general anesthesia (GA) although this procedure is still associated with morbidity rate. The aim of this study is to determine the effectiveness and safety of regional anesthesia (RA) compared with GA in thoracoscopic lung biopsy procedures done on patients with idiopathic pulmonary fibrosis (IPF)...
January 2018: Saudi Journal of Anaesthesia
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