Crystal structures of sulfonamide protected bicyclic guanidines: ( S )-8-{[( tert -butyl-dimethyl-sil-yl)-oxy]meth-yl}-1-[(2,2,4,6,7-penta-methyl-2,3-di-hydro-benzo-furan-5-yl)sulfon-yl]-1,3,4,6,7,8-hexa-hydro-2 H -pyrimido[1,2- a ]pyrimidin-1-ium tri-fluoro-methane-sulfonate and ( S )-8-(iodo-meth-yl)-1-tosyl-1,3,4,6,7,8-hexa-hydro-2 H -pyrimido[1,2- a ]pyrimidin-1-ium iodide.
Jamal M H Alaboosh, Steven P Hill, Benson M Kariuki, James E Redman
Two compounds, ( S )-8-{[( tert -butyl-dimethyl-sil-yl)-oxy]meth-yl}-1-[(2,2,4,6,7-penta-methyl-2,3-di-hydro-benzo-furan-5-yl)sulfon-yl]-1,3,4,6,7,8-hexa-hydro-2 H -pyrimido[1,2- a ]pyrimidin-1-ium tri-fluoro-methane-sulfonate, C27 H46 N3 O4 SSi+ ·CF3 O3 S- , ( 1 ) and ( S )-8-(iodo-meth-yl)-1-tosyl-1,3,4,6,7,8-hexa-hydro-2 H -pyrimido[1,2- a ]pyrimidin-1-ium iodide, C15 H21 IN3 O2 S+ ·I- , ( 2 ), have been synthesized and characterized. They are bicyclic guanidinium salts and were synthesized from N -( tert -but-oxy-carbon-yl)-l-me-thio-nine (Boc-l-Met-OH)...
March 1, 2024: Acta Crystallographica. Section E, Crystallographic Communications