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Zhe Zhang, Jun He, Bin Du, Fengchan Zhang, Kuikui Guo, Yiping Wang
A compact dual-cavity Fabry-Perot interferometer (DC-FPI) sensor is proposed and demonstrated based on a hollow-core photonic bandgap fiber (HC-PBF) spliced with a hollow-core fiber (HCF). The HC-PBF, which has low transmission loss, was used as the first FPI cavity and also acted as a bridge between the lead-in single-mode fiber and the HCF. The HCF was used as the second FPI cavity and also acted as a micro gas inlet into the first FPI cavity. A DC-FPI sensor with different cavity lengths of 226 and 634 μm in the first FPI and the second FPI was created...
December 15, 2018: Optics Letters
Alvard Ter-Karapetyan, Simon M F Triphan, Bertram J Jobst, Angela F Anjorin, Julia Ley-Zaporozhan, Sebastian Ley, Oliver Sedlaczek, Jürgen Biederer, Hans-Ulrich Kauczor, Peter M Jakob, Mark O Wielpütz
PURPOSE: 4D perfusion magnetic resonance imaging (MRI) with intravenous injection of contrast agent allows for a radiation-free assessment of regional lung function. It is therefore a valuable method to monitor response to treatment in patients with chronic obstructive pulmonary disease (COPD). This study was designed to evaluate its potential for monitoring short-term response to hyperoxia in COPD patients. MATERIALS AND METHODS: 19 prospectively enrolled COPD patients (median age 66y) underwent paired dynamic contrast-enhanced 4D perfusion MRI within 35min, first breathing 100% oxygen (injection 1, O2) and then room air (injection 2, RA), which was repeated on two consecutive days (day 1 and 2)...
2018: PloS One
Christopher Napier, Christopher L MacLean, Jessica Maurer, Jack E Taunton, Michael A Hunt
BACKGROUND: Running-related injury (RRI) rates are high and may be associated with increased peak braking forces (PBF) and vertical loading rates. Gait retraining has been suggested by some experts to be an effective method to reduce loading parameters. OBJECTIVES: To investigate 1) whether PBF could be decreased following an 8-session gait retraining program among a group of female recreational runners and 2) the self-selected kinematic strategies to achieve this reduction...
December 7, 2018: Journal of Orthopaedic and Sports Physical Therapy
Yuan-Yuei Chen, Wen-Hui Fang, Chung-Ching Wang, Tung-Wei Kao, Yaw-Wen Chang, Hui-Fang Yang, Chen-Jung Wu, Yu-Shan Sun, Wei-Liang Chen
The association between anthropometric indices with chronic kidney disease (CKD) was examined previously. However, the effect of body fat on renal function was not determined clearly. Our aim was to investigate the association of percent body fat (PBF) and renal function in adult population from health examination in Tri-Service General Hospital (2010-2016). 35087 participants aged 20 years and older were enrolled in the study. PBF was measured by bioelectrical impedance analysis (BIA). Estimation of renal function was performed by Taiwanese MDRD equation...
November 23, 2018: Scientific Reports
Chun Mao, Bo Huang, Ying Wang, Yijian Huang, Longfei Zhang, Yu Shao, Yiping Wang
We propose and experimentally demonstrate a highly sensitive gas pressure sensor based on a near-balanced Mach-Zehnder interferometer (MZI) and constructed by hollow-core photonic bandgap fiber (HC-PBF) in this paper. The MZI is simply constructed by fusion splicing two HC-PBFs, which are of slightly different lengths, between two 3-dB couplers. The two output ends of each coupler are approximately equal in length, to ensure that the optical path variations of the MZI only result from the differences in the lengths between the two HC-PBFs...
November 12, 2018: Optics Express
Elena Bassoli, Antonella Sola, Mattia Celesti, Sandro Calcagnile, Carlo Cavallini
In spite of the fast growth of laser-based powder bed fusion (L-PBF) processes as a part of everyday industrial practice, achieving consistent production is hampered by the scarce repeatability of performance that is often encountered across different additive manufacturing (AM) machines. In addition, the development of novel feedstock materials, which is fundamental to the future growth of AM, is limited by the absence of established methodologies for their successful exploitation. This paper proposes a structured procedure with a complete test plan, which defines step-by-step the standardized actions that should be taken to optimize the processing parameters and scanning strategy in L-PBF of new alloy grades...
November 22, 2018: Materials
Damoon Ashtary-Larky, Sevana Daneghian, Meysam Alipour, Hossein Rafiei, Matin Ghanavati, Reza Mohammadpour, Wesam Kooti, Pouya Ashtary-Larky, Reza Afrisham
Background: The first-line strategy for the treatment of obesity is weight loss (WL) through decreasing calorie intake. However, a diet that is capable of attenuating fat free mass decline following WL is preferred. Furthermore, it is required to choose proper measurements and appropriate obesity-assessment indices to monitor weight and body composition during WL program. Methods: A total of 68 adults with overweight and/or obesity underwent a WL program (rapid and slow WL)...
October 2018: International Journal of Endocrinology and Metabolism
Flávia Jôse Oliveira Alves, Daiane Borges Machado, Maurício L Barreto
PURPOSE: There is a growing awareness of the economic and contextual factors that may play a role in the aetiology of suicide. The Programa Bolsa Família (PBF) the Brazilian conditional cash transfer programme, established in 2004, aims to attenuate the effects of poverty of Brazilians. Our study aims to evaluate the effect of Bolsa Família Programme (BFP) coverage on suicide rates in Brazilian municipalities. METHODS: We conducted an ecological study using 2004-2012 panel data for 5507 Brazilian municipalities...
November 19, 2018: Social Psychiatry and Psychiatric Epidemiology
Yuan-Yuei Chen, Wen-Hui Fang, Chung-Ching Wang, Tung-Wei Kao, Yaw-Wen Chang, Chen-Jung Wu, Yi-Chao Zhou, Yu-Shan Sun, Wei-Liang Chen
OBJECTIVE: The effect of obesity-induced metabolic abnormalities on bone mineral density (BMD) and osteoporosis are well established. However, the association between metabolically healthy obesity (MHO) and BMD remains unclear. Our aim was to investigate whether different obesity phenotypes in MHO were associated with BMD in a cross-sectional study. METHODS: All eligible adults receiving a health examination at the Tri-Service General Hospital from 2010 to 2016 were included...
2018: PloS One
Anton du Plessis, Philip Sperling, Andre Beerlink, Willie B du Preez, Stephan G le Roux
X-ray micro computed tomography (microCT) can be applied to analyse powder feedstock used in additive manufacturing. In this paper, we demonstrate a dedicated workflow for this analysis method, specifically for Ti6Al4V powder typically used in commercial powder bed fusion (PBF) additive manufacturing (AM) systems. The methodology presented includes sample size requirements, scan conditions and settings, reconstruction and image analysis procedures. We envisage this method will support standardization in powder analysis in the additive manufacturing community...
2018: MethodsX
Rosane Teresinha Heck, Mariane Bittencourt Fagundes, Alexandre José Cichoski, Cristiano Ragagnin de Menezes, Juliano Smanioto Barin, José Manuel Lorenzo, Roger Wagner, Paulo Cezar Bastianello Campagnol
Direct incorporation of rosemary leaves into chia oil (CO) was performed by ultrasound-assisted extraction (UAE) and conventional maceration extraction (CME). CO was microencapsulated and used in burgers, as follows: control (20% pork back fat (PBF)); HCO (10% PBF + 7.5% water +2.5% unencapsulated CO); HM1 (10% PBF + 10% CO microparticles); HM2 (10% PBF + 10% CO microparticles enriched by UAE) and HM3 (10% PBF + 10% CO microparticles enriched by CME). The volatile compounds and the sensory properties (Check-All-That-Apply and overall acceptability) of burgers were evaluated at days 1 and 120 of frozen storage...
February 2019: Meat Science
Kazue Watanabe, Tomohide Tsukahara, Shingo Toji, Shogo Saitoh, Yoshihiko Hirohashi, Munehide Nakatsugawa, Terufumi Kubo, Takayuki Kanaseki, Hidekazu Kameshima, Takeshi Terui, Noriyuki Sato, Toshihiko Torigoe
For the efficacy of peptide vaccination immunotherapy for patients with cancer, endogenous expression of the target peptide/HLA on cancer cells is required. However, it is difficult to evaluate the expression status of a peptide/HLA complex because of the lack of a soluble T cell receptor (TCR) that reacts with TAA with high avidity. In this study, we developed two soluble TCR-multimers that were each directed to tumor-associated antigens (TAAs), survivin2B and PBF in the context of HLA-A24 (SVN-2B TCR-multimer and PBF TCR-multimer, respectively), from CTL clones that were established from peptide-vaccinated patients...
October 30, 2018: Cancer Science
Fernando Uliana Kay, Marcelo A Beraldo, Maria A M Nakamura, Roberta De Santis Santiago, Vinicius Torsani, Susimeire Gomes, Rollin Roldan, Mauro R Tucci, Suhny Abbara, Marcelo B P Amato, Edson Amaro
OBJECTIVE: The aims of this study were to investigate the ability of contrast-enhanced dual-energy computed tomography (DECT) for assessing regional perfusion in a model of acute lung injury, using dynamic first-pass perfusion CT (DynCT) as the criterion standard and to evaluate if changes in lung perfusion caused by prone ventilation are similarly demonstrated by DECT and DynCT. METHODS: This was an institutional review board-approved study, compliant with guidelines for humane care of laboratory animals...
November 2018: Journal of Computer Assisted Tomography
Y-Ling Chi, Mohamed Gad, Sebastian Bauhoff, Kalipso Chalkidou, Itamar Megiddo, Francis Ruiz, Peter Smith
No abstract text is available yet for this article.
2018: BMJ Global Health
Yuan-Yuei Chen, Wen-Hui Fang, Chung-Ching Wang, Tung-Wei Kao, Yaw-Wen Chang, Hui-Fang Yang, Chen-Jung Wu, Yu-Shan Sun, Wei-Liang Chen
Adverse systemic effect caused by betel nut had been reported for decades. Our aim was to determine whether betel nut had detrimental impact on the development of colorectal polyps in general population. Participants who attended health examinations at the Tri-Service General Hospital (TSGH) from 2010 to 2016 were included in the study. The habit of betel nut chewing was obtained from a self-reported questionnaire. Colorectal polyps were diagnosed by colonoscopies operated by experienced physicians. A logistic regression model was used for the association between betel nut chewing with the presence of colorectal polyps...
2018: PloS One
Han-Gook Cho, Lester Andrews
The insertion products of laser-ablated Pb atom reactions with ethane and mono-, di-, tri-, and tetrahalomethanes in excess argon were prepared and identified from their matrix infrared spectra on the basis of DFT computed frequencies and observed isotopic shifts. Unlike the lighter elements in group 14, the heaviest member lead exists primarily in the oxidation state 2+ using 6p orbitals in reaction products due to relativistic contraction of the 6s orbital. The C-Pb-X (X = H, F, Cl) bond is close to a right angle, indicating that Pb contributes mostly p-character to the C-Pb and Pb-X bonds...
November 15, 2018: Journal of Physical Chemistry. A
Till F Kaireit, Andreas Voskrebenzev, Marcel Gutberlet, Julia Freise, Bertram Jobst, Hans-Ulrich Kauczor, Tobias Welte, Frank Wacker, Jens Vogel-Claussen
BACKGROUND: Perfusion-weighted noncontrast-enhanced proton lung MRI during free breathing is maturing as a novel technique for assessment of regional lung perfusion, but has not yet been validated in chronic obstructive pulmonary disease (COPD) patients. PURPOSE: To compare pulmonary parenchymal perfusion assessed by noncontrast-enhanced perfusion-weighted phase-resolved functional lung (PREFUL)-MRI with lung perfusion determined with dynamic gadolinium-enhanced (DCE)-MRI and with lung function test parameters...
October 22, 2018: Journal of Magnetic Resonance Imaging: JMRI
Maria Paola Bertone, Haja Wurie, Mohamed Samai, Sophie Witter
BACKGROUND: As performance-based financing (PBF) has been increasingly implemented in low-income countries, a growing literature has developed, assessing its effectiveness and, more recently, focussing on the political dynamics of PBF introduction and implementation. This study contributes to the latter body of literature by exploring decision-making processes on PBF in Sierra Leone during the 2010-2017 period. Sierra Leone presents an interesting case because of the 'start-stop-start' trajectory of PBF...
October 20, 2018: Globalization and Health
Jessica Gergen, Yogesh Rajkotia, Julia Lohmann, Nirmala Ravishankar
BACKGROUND: Performance-based financing (PBF) reforms aim to directly influence health worker behavior through changes to institutional arrangements, accountability structures, and financial incentives based on performance. While there is still some debate about whether PBF influences extrinsic or intrinsic motivators, recent research finds that PBF affects both. Against this backdrop, our study presents findings from a process evaluation of a PBF program in Mozambique, exploring the perceived changes to both internal and external drivers of health worker motivation associated with PBF...
October 19, 2018: Human Resources for Health
Jason Boehme, Natacha Le Moan, Rebecca J Kameny, Alexandra Loucks, Michael J Johengen, Amy L Lesneski, Wenhui Gong, Tina Davis, Kevin Tanaka, Andrew Davis, Youping He, Janel Long-Boyle, Vijay Ivaturi, Jogarao V S Gobburu, Jonathan A Winger, Stephen P Cary, Sanjeev A Datar, Jeffrey R Fineman, Ana Krtolica, Emin Maltepe
The heart exhibits the highest basal oxygen (O2) consumption per tissue mass of any organ in the body and is uniquely dependent on aerobic metabolism to sustain contractile function. During acute hypoxic states, the body responds with a compensatory increase in cardiac output that further increases myocardial O2 demand, predisposing the heart to ischemic stress and myocardial dysfunction. Here, we test the utility of a novel engineered protein derived from the heme-based nitric oxide (NO)/oxygen (H-NOX) family of bacterial proteins as an O2 delivery biotherapeutic (Omniox-cardiovascular [OMX-CV]) for the hypoxic myocardium...
October 2018: PLoS Biology
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