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Patient reported outcome measure

Esmee M Reijnierse, Sjors Verlaan, Vivien K Pham, Wen Kwang Lim, Carel G M Meskers, Andrea B Maier
Background: Approximately 10% of older adults is annually admitted to a hospital. Hospitalisation is associated with a higher risk of falls and mortality after discharge. This study aimed to identify predictors at admission for falls and mortality three months post-discharge in hospitalised older patients. Methods: The EMPOWER study is an observational, prospective longitudinal inception cohort of 378 patients aged 70 years and older who were subsequently admitted to a tertiary hospital (the Netherlands)...
December 14, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Ebrahim S Elborgy, Matthew R Starr, Jacek G Kotowski, Jackson E Abou Chehade, Raymond Iezzi
PURPOSE: To report visual and anatomical outcomes after the repair of chronic idiopathic macular holes (MHs) with no face-down positioning. METHODS: We conducted a retrospective review of chronic MH cases of greater than 1-year duration that were repaired through pars plana vitrectomy with broad internal limiting membrane peeling and no face-down positioning between March 2009 and December 2017. There were 18 eyes of 18 patients that met inclusion criteria. Patients with MH duration of less than 1 year and without at least 1 month of follow-up were excluded...
December 6, 2018: Retina
Christina C Lawson, Candice Y Johnson, Feiby L Nassan, Thomas H Connor, James M Boiano, Carissa M Rocheleau, Jorge E Chavarro, Janet W Rich-Edwards
Findings from this cross-sectional study indicate a need for expanded training in safe handling practices. ABSTRACT: Background: Many antineoplastic (chemotherapeutic) drugs are known or probable human carcinogens, and many have been shown to be reproductive toxicants in cancer patients. Evidence from occupational exposure studies suggests that health care workers who have long-term, low-level occupational exposure to antineoplastic drugs have an increased risk of adverse reproductive outcomes...
December 12, 2018: American Journal of Nursing
Rickard P Brånemark, Kerstin Hagberg, Katarzyna Kulbacka-Ortiz, Örjan Berlin, Björn Rydevik
INTRODUCTION: Direct skeletal attachment of prostheses has previously been shown to improve patient-reported outcome (PRO) measures of individuals with transfemoral amputation (TFA) at 2-year follow-up. This prospective study reports the outcomes at 5-year follow-up. METHODS: A total of 51 patients (55 legs) with TFA were included in a prospective study. Complications, success rate, and PRO measures were followed for 5 years. RESULTS: The cumulative fixture survival rate at 5 years was 92%, and the revision-free survival rate was 45%...
December 13, 2018: Journal of the American Academy of Orthopaedic Surgeons
Adil H Haider, Juan P Herrera-Escobar, Syeda S Al Rafai, Alyssa F Harlow, Michel Apoj, Deepika Nehra, George Kasotakis, Karen Brasel, Haytham M A Kaafarani, George Velmahos, Ali Salim
OBJECTIVE: The aim of this study was to determine factors associated with patient-reported outcomes, 6 to 12 months after moderate to severe injury. SUMMARY OF BACKGROUND DATA: Due to limitations of trauma registries, we have an incomplete understanding of factors that impact long-term patient-reported outcomes after injury. As 96% of patients survive their injuries, several entities including the National Academies of Science, Engineering and Medicine have called for a mechanism to routinely follow trauma patients and determine factors associated with survival, patient-reported outcomes, and reintegration into society after trauma...
December 13, 2018: Annals of Surgery
Mark D Stegall, K Troy Somerville, Matthew Everly, Roslyn B Mannon, Osama A Gaber, M Roy First, Neetu Agashivala, Vanessa Perez, Kenneth A Newell, Randall E Morris, Debra Sudan, Klaus Romero, Sonya Eremenco, Maria Mattera, Nicole Spear, Amy C Porter, Inish O'Doherty
The Transplant Therapeutics Consortium (TTC) is a public-private partnership between the Food and Drug Administration and the transplantation community including the transplantation societies and members of the biopharmaceutical industry. The TTC was formed to accelerate the process of developing new medical products for transplant patients. The initial goals of this collaboration are: 1) To define which aspects of the kidney transplant drug-development process have clear needs for improvement from an industry and regulatory perspective; 2) To define which of the unmet needs in the process could be positively impacted through the development of specific drug development tools based on available data; and 3) To determine the most appropriate pathway to achieve regulatory acceptance of the proposed process-accelerating tools...
December 14, 2018: American Journal of Transplantation
Lourdes Montes-Jovellar, Alvaro Carrillo, Alfonso Muriel, Rafael Barbera, Fatima Sanchez, Ignacio Cobeta
BACKGROUND: The main objective of this study was to perform the adaptation and cultural translation and validation of the MD Anderson Dysphagia Inventory (MDADI) questionnaire for the Spanish language. METHODS: A total of 69 patients were diagnosed with head and neck cancer treated with surgery; radiotherapy and chemoradiotherapy were included. MDADI was translated and a feasibility, internal consistency, test-retest reliability, and construct validity were assessed...
December 14, 2018: Head & Neck
Sarah C Shepherd, Belinda Hacking, Louise M Wallace, Sarah E Murdoch, Jeff Belkora
OBJECTIVE: UK healthcare policy for improving cancer outcomes supports participation of patients in care decisions with clinicians. Consultation Planning, Recording and Summarising (CPRS) has shown evidence of increasing patient decision self-efficacy, reducing uncertainty and regret of decisions. This is the first trial of CPRS within the colorectal cancer population and delivered over serial medical consultations. METHODS: This Randomised Controlled Trial compared usual care to the addition of CPRS over consecutive oncology consultations with newly diagnosed Colorectal Cancer (CRC) patients in Edinburgh, Scotland...
December 13, 2018: Psycho-oncology
Tanya M Wildes, Sascha A Tuchman, Heidi D Klepin, Joseph Mikhael, Kathryn Trinkaus, Keith Stockerl-Goldstein, Ravi Vij, Graham Colditz
BACKGROUND/OBJECTIVES: The incidence of myeloma in older adults is increasing, yet little is known about geriatric impairments in these patients. We aimed to examine the prevalence of geriatric impairments in older adults with myeloma and the association between geriatric assessment and autologous stem cell transplant eligibility. DESIGN: Prospective cohort study. SETTING: Two academic medical centers. PARTICIPANTS: A total of 40 adults 65 years and older with newly diagnosed myeloma were enrolled...
December 13, 2018: Journal of the American Geriatrics Society
Ivana Petrovic, Hina Panchal, Paula Demetrio De Souza Franca, Marisol Hernandez, Colleen C McCarthy, Jatin P Shah
BACKGROUND: Segmental mandibulectomy impairs health-related quality of life (QoL), by altering speech, mastication, swallowing, and facial aesthetics. Fibula free flap (FFF) used for mandible reconstruction is known to improve outcomes; however, minimal information exists in the literature regarding patient-reported outcomes. We aim to assess how current studies evaluate patient perception following segmental mandibulectomy and FFF mandible reconstruction. METHODS: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a search was conducted for publications involving FFF mandible reconstruction from 2005 to 2017 using PubMed, Cochrane, EMBASE, Web of Science, and PsychInfo...
December 12, 2018: Head & Neck
Vanessa L Malcarne, Celine M Ko, Scott C Roesch, Rajni Banthia, Georgia Robins Sadler
OBJECTIVE: Prostate cancer can have a significant negative impact on patients and their spouses. Problem-solving therapy (PST) has been shown to help reduce distress and improve quality of life among cancer and caregiver populations. This study tested the efficacy of PST for spouses of men with prostate cancer. METHODS: Spouses of men diagnosed with prostate cancer within the past 18 months (N = 164) were randomly assigned to PST (n = 78) or usual psychosocial care (UPC; n = 86)...
December 11, 2018: Psycho-oncology
Beenish Nafees, Zenia M Størling, Charlotte Hindsberger, Andrew Lloyd
BACKGROUND: Leakage is a major concern for people who use a stoma, but people's experience and its impact is not well understood. This study aimed to establish a definition of leakage through clinical and user input. This information was used to develop and validate a new measurement tool to understand the impact of leakage for people using a stoma appliance, in the UK, US, France, and Denmark. METHODS: Participants were recruited from a panel of users, hosted by Coloplast, that includes people who currently use Coloplast products...
December 14, 2018: Health and Quality of Life Outcomes
Shanshan Qin, Lauren Nelson, Lori McLeod, Sonya Eremenco, Stephen Joel Coons
PURPOSE: The US Food and Drug Administration (FDA) 2009 guidance for industry on patient-reported outcome (PRO) measures describes how the Agency evaluates the psychometric properties of measures intended to support medical product labeling claims. An important psychometric property is test-retest reliability. The guidance lists intraclass correlation coefficients (ICCs) and the assessment time period as key considerations for test-retest reliability evaluations. However, the guidance does not provide recommendations regarding ICC computation, nor is there consensus within the measurement literature regarding the most appropriate ICC formula for test-retest reliability assessment...
December 13, 2018: Quality of Life Research
Aaron Yarlas, Stephen M Maher, Martha S Bayliss, Andrew Lovley, Joseph C Cappelleri, Marco D DiBonaventura
Patients with ulcerative colitis, a type of inflammatory bowel disease, report negative impacts of disease symptoms on work-related outcomes, including absenteeism and presenteeism. As a way to better understand the impact of this disease and its treatment on work-related outcomes, the current review examines the use of the Work Productivity and Activity Impairment Questionnaire (WPAI), a patient-reported outcomes measure of absenteeism, presenteeism, and impairment in other activities, in studies of patients with ulcerative colitis...
December 13, 2018: Journal of patient-reported outcomes
Timothy R Niedzielak, Bijan J Ameri, Blaze Emerson, Rushabh M Vakharia, Martin W Roche, John P Malloy
Background: Due to increased postoperative complications with anterior cervical discectomy and fusion (ACDF), there has been an increasing interest in the use of cervical disc arthroplasty (CDA). Advancements in prosthetic designs and techniques have improved patient reported outcome measurements and minimized revision rates. There is a paucity in the literature regarding recent trends in CDA utilization and revision rates. The purpose of this study was to determine annual primary and revision CDA trends with the use of an administrative database...
September 2018: Journal of Spine Surgery (Hong Kong)
Matilde M Vaghi, Rudolf N Cardinal, Annemieke M Apergis-Schoute, Naomi A Fineberg, Akeem Sule, Trevor W Robbins
BACKGROUND: In obsessive-compulsive disorder (OCD), actions persist despite being inappropriate to the situation and without relationship to the overall goal. Dysfunctional beliefs have traditionally been postulated to underlie this condition. More recently, OCD has been characterized in terms of an imbalance between the goal-directed and the habit systems. To test these competing hypotheses, we used a novel experimental task designed to test subjective action-outcome knowledge of the effectiveness of actions (i...
October 9, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Tammie McIntyre, Carmel Taylor, Michael Bailey, Daryl Jones
BACKGROUND: There is a lack of knowledge about tasks intensive care unit liaison nurses (ICU LNs) perform during patient review, despite this role operating in at least 31 acute care hospitals in Australia. OBJECTIVES: To evaluate the tasks that ICU LNs perform during patient review in the following referral subcategories: review after ICU discharge, rapid response team (RRT) review, and ward referral. METHODS: A 2-month prospective observational study using standardised case report forms to collect data on patients reviewed by ICU LNs in 20 Australian hospitals was conducted...
December 10, 2018: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
Nima Eftekhary, James E Feng, Afshin A Anoushiravani, Ran Schwarzkopf, Jonathan M Vigdorchik, William J Long
BACKGROUND: The Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) score is a nationally standardized measure of a patient's inpatient experience. This study aims to assess whether HCAHPS scores differ between patients undergoing primary total joint arthroplasty (TJA) and patients undergoing revision TJA. METHODS: Patients who underwent primary or revision total hip or total knee arthroplasty (THA or TKA) and returned a completed HCAHPS survey were included in this study...
November 20, 2018: Journal of Arthroplasty
Hsin-Yin Lin, Hsiao-Wen Tsai, Kuan-Hao Tsui, Ya-Fen An, Ching-Chuan Lo, Zi-Han Lin, Wen-Shiung Liou, Peng-Hui Wang
OBJECTIVE: Female pelvic floor disorders, including female stress urinary incontinence (SUI) or sexual dysfunction are notorious for affecting the quality of women's life. It is reported that laser therapy might result in collagen remodeling and improvement in tissue firmness. The study was conducted to evaluate the short-term outcome of female pelvic floor disorders treated by laser therapy. MATERIALS AND METHODS: Women with self-reported symptoms of female pelvic floor disorders (limited to SUI and sexual dysfunction) were included in the study...
December 2018: Taiwanese Journal of Obstetrics & Gynecology
Tomo Ando, Said Ashraf, Pedro A Villablanca, Tesfaye A Telila, Hisato Takagi, Cindy L Grines, Luis Afonso, Alexandros Briasoulis
Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) is a rare but life-threatening complication. Paravalvular regurgitation, compression of native leaflets, and space between transcatheter valve prosthesis and native valves could dispose TAVI recipients at increased risk of IE compared with SAVR. To assess the comparative risk of IE between TAVI and SAVR, we performed a systematic review and meta-analysis. A literature search of PUBMED and EMBASE was performed to identify randomized controlled trials that reported the event rate of IE in both TAVI and SAVR...
December 3, 2018: American Journal of Cardiology
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