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Patient reported outcome measure

Fabrizio Luca, Danielle K Craigg, Maheswari Senthil, Matthew J Selleck, Blake D Babcock, Mark E Reeves, Carlos A Garberoglio
Several studies have reported high rates of urogenital dysfunction after open and laparoscopic surgery for rectal cancer. Robotic surgery has several features that could facilitate identification and preservation of autonomic nerves. This manuscript aims to summarize the literature regarding urogenital function after robotic rectal cancer surgery and focus on technical aspects of nerve-sparing total mesorectal excision. Comprehensive searches were conducted through online databases. Selection criteria included: original articles assessing urinary and sexual function after robotic surgery of males and/or females with standardized questionnaires...
August 17, 2018: Updates in Surgery
Anatole V Wiik, Mads Brevadt, Hardeep Johal, Kartik Logishetty, Oliver Boughton, Adeel Aqil, Justin P Cobb
BACKGROUND: The purpose of this study was to examine the gait pattern of total hip arthroplasty (THA) patients with a new short femoral stem at different speeds and inclinations. MATERIALS AND METHODS: A total of 40 unilateral THA patients were tested on an instrumented treadmill. They comprised two groups (shorter stemmed THA n = 20, longer stemmed THA n = 20), both which had the same surgical posterior approach. The shorter femoral stemmed patients were taken from an ongoing hip trial with minimum 12 months postop...
August 17, 2018: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
Raja Atreya, Walter Reinisch, Laurent Peyrin-Biroulet, Franco Scaldaferri, Charlotte Admyre, Thomas Knittel, Jan Kowalski, Markus Friedrich Neurath, Christopher Hawkey
BACKGROUND: The Toll-like-receptor 9 (TLR-9) agonist cobitolimod (DIMS0150, Kappaproct® ) is a promising therapeutic option for ulcerative colitis (UC) patients. AIMS: The objectives of this post-hoc analysis using the COLLECT study data was to investigate the clinical effects of cobitolimod using patient-reported-outcomes (PRO) defined endpoints. METHODS: Dual topical administration of cobitolimod was studied in a randomised, multicentre clinical trial named COLLECT in moderate-to-severe UC patients...
June 22, 2018: Digestive and Liver Disease
Verena R Juncal, Mostafa Hanout, Filiberto Altomare, David R Chow, Louis R Giavedoni, Rajeev H Muni, David T Wong, Alan R Berger
OBJECTIVE: To report the anatomical and visual outcomes of patients with thick submacular hemorrhage (SMH) treated with pars plana vitrectomy (PPV), subretinal tissue plasminogen activator (t-PA), and pneumatic displacement. DESIGN: Single-centre, retrospective case series. PARTICIPANTS: A total of 99 eyes of 99 consecutive patients with thick SMH secondary to any underlying etiology treated with PPV with subretinal t-PA and pneumatic displacement by 6 vitreoretinal surgeons at St...
August 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Elizabeth J Mayer-Davis, David M Maahs, Michael Seid, Jamie Crandell, Franziska K Bishop, Kimberly A Driscoll, Christine M Hunter, Jessica C Kichler, Debra Standiford, Joan M Thomas
BACKGROUND: Adolescents with type 1 diabetes commonly have poor glycaemic control. We aimed to test the efficacy of a newly developed adaptive behavioral intervention (Flexible Lifestyles Empowering Change; FLEX) on metabolic and psychosocial outcomes in adolescents with type 1 diabetes. METHODS: Young people (13-16 years, type 1 diabetes duration >1 year, HbA1c of 64-119 mmol/mol [8·0-13·0%], and without other serious medical conditions or pregnancy) from two clinical sites (Colorado and Ohio, USA) were eligible for enrolment...
September 2018: Lancet Child & Adolescent Health
Ghassan Mehio, Mohamed Morsy, Cenk Cayci, M Diya Sabbagh, Alexander Y Shin, Allen T Bishop, Steven L Moran, Brian T Carlsen
BACKGROUND: The medial femoral condyle (MFC) free vascularized bone flap is a valuable alternative to other types of vascularized bone grafts. The donor site morbidity and functional outcomes after flap harvest have not been fully appreciated. Herein, we report the postoperative outcomes and analyze the impact of increasing the size of the flap on the knee donor site morbidity. METHODS: A retrospective chart review of patients who underwent MFC flap between 2001 and 2012 at our institution was done...
August 9, 2018: Plastic and Reconstructive Surgery
Maia S Kredentser, Marcus Blouw, Nicole Marten, Jitender Sareen, O Joseph Bienvenu, Jennifer Ryu, Brooke E Beatie, Sarvesh Logsetty, Lesley A Graff, Shauna Eggertson, Sophia Sweatman, Braeden Debroni, Nina Cianflone, Rakesh C Arora, Ryan Zarychanski, Kendiss Olafson
OBJECTIVES: Critical illness can have a significant psychological impact on patients and their families. To inform the design of a larger trial, we assessed feasibility of ICU diaries and psychoeducation to prevent posttraumatic stress disorder, depression, and anxiety following ICU stays. DESIGN: Four-arm pilot randomized controlled trial. SETTING: A 10-bed tertiary ICU in Winnipeg, MB, Canada. PATIENTS: Critically ill patients greater than 17 years old with predicted ICU stays greater than 72 hours and mechanical ventilation duration greater than 24 hours...
August 16, 2018: Critical Care Medicine
Domenico Giacco, Maev Conneely, Tumseela Masoud, Erin Burn, Stefan Priebe
BACKGROUND: Observational research has found that involuntary treatment provides limited benefits in terms of long-term clinical outcomes. Our aim was to review literature on existing interventions in order to identify helpful approaches to improve outcomes of involuntary treatment. METHODS: This systematic review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines. Seven databases (AMED, PsycINFO, Embase Classic, Embase 1974-2017, CINAHL, MEDLINE, and BNI) were searched and the results were analysed in a narrative synthesis...
August 14, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
Alexander Tuchman, Lawrence G Lenke, Meghan Cerpa, Michael G Fehlings, Stephen J Lewis, Christopher I Shaffrey, Kenneth M C Cheung, Leah Yacat Carreon, Mark B Dekutoski, Frank J Schwab, Oheneba Boachie-Adjei, Khaled Kebaish, Christopher P Ames, Yong Qiu, Yukihiro Matsuyama, Benny T Dahl, Hossein Mehdian, Ferran Pellisé, Sigurd H Berven
BACKGROUND CONTEXT: Scoli-RISK-1 is a multicenter prospective cohort designed to study neurologic outcomes following complex adult spinal deformity (ASD). The effect of unilateral versus bilateral postoperative motor deficits on the likelihood of long term recovery has not been previously studied in this population. PURPOSE: Evaluate if bilateral postoperative neurologic deficits have a worse recovery than unilateral deficits. STUDY DESIGN: Secondary analysis of a prospective, multicenter, international cohort study...
August 14, 2018: Spine Journal: Official Journal of the North American Spine Society
Elisabeth Schilbred Eriksen, Shashi Gulati, Ketil Moen, Per Johan Wisth, Sigbjørn Løes
PURPOSE: The study purpose was to assess whether mandibular setback surgery by intraoral vertical ramus osteotomy (IVRO) induces obstructive apnea and hypopnea in healthy Class III patients without a history of respiratory dysfunction. We hypothesized that the apnea-hypopnea index (AHI) would not exceed 5 events per hour after surgery. PATIENTS AND METHODS: A prospective cohort study was conducted. The sample was composed of healthy Class III patients without a history of obstructive sleep apnea treated with isolated mandibular setback surgery by the IVRO procedure at a university hospital...
July 24, 2018: Journal of Oral and Maxillofacial Surgery
David Schneider, Manuel Sancho-Puchades, Goran I Benic, Christoph Hf Hämmerle, Ronald E Jung
The objectives of this study were to compare conventional and computer-assisted implant planning and placement (CAIPP) protocols regarding surgical planning predictability, intraoperative complications, and patient-centered outcomes. Partially edentulous patients (N = 73) were randomly allocated to one of three treatment groups: control (C, n = 26), with preoperative planning based on conventional radiography and freehand implant placement; and test 1 (T1, n = 24) and test 2 (T2, n = 23), with two different CAIPP protocols...
2018: International Journal of Periodontics & Restorative Dentistry
Yuanqing Pan, Kehu Yang, Xiue Shi, Haiqian Liang, Xiping Shen, Renjie Wang, Li Ma, Qi Cui, Runze Yu, Yi Dong
IMPORTANCE: Acupuncture can help reduce unpleasant side effects associated with endocrine therapy for breast cancer. Nevertheless, comprehensive evaluation of current evidence from randomized controlled trials(RCTs) is lacking. OBJECTIVE: To estimate the efficacy of acupuncture for the reduction of hormone therapy-related side effects in breast cancer patients. EVIDENCE REVIEW: RCTs of acupuncture in breast cancer patients that examined reductions in hormone therapy-related side effects were retrieved from PubMed, EMBASE, Web of Science, Ovid MEDLINE, and Cochrane Library databases through April 2016...
September 2018: Integrative Cancer Therapies
Wahid Abdul, Ben Hickey, Anthony Perera
BACKGROUND: Conservative treatment or debridement is generally sufficient for Freiberg disease grades I and II but operative intervention for the late stages of the disease process (III-V) is more challenging. Debridement alone is not sufficient and various forms of arthroplasty have been put forward. We have evaluated the outcomes of patients treated with an interpositional arthroplasty technique using a pedicle graft of periosteum and fat made into a "Rollmop" spacer for severe Freiberg disease...
August 17, 2018: Foot & Ankle International
Rishad Khan, Joanne Plahouras, Bradley C Johnston, Michael A Scaffidi, Samir C Grover, Catharine M Walsh
BACKGROUND: Endoscopy has traditionally been taught with novices practicing on real patients under the supervision of experienced endoscopists. Recently, the growing awareness of the need for patient safety has brought simulation training to the forefront. Simulation training can provide trainees with the chance to practice their skills in a learner-centred, risk-free environment. It is important to ensure that skills gained through simulation positively transfer to the clinical environment...
August 17, 2018: Cochrane Database of Systematic Reviews
Sahar Dadkhahfar, Kaveh Fadakar, Reza M Robati
Fractional lasers such erbium:YAG (Er:YAG) are among popular options for facial rejuvenation. Lasers with infrared wavelength ranges such as long pulse Nd:YAG have been used in nonablative rejuvenation of skin with variable outcomes. In this study, we plan to compare safety and efficacy of fractional Er:YAG and long pulse Nd:YAG for facial rejuvenation applying objective and subjective measurements. Twenty-five patients with Glogau photo aging scale of II to IV were recruited in this randomized face-split double-blind controlled trial...
August 16, 2018: Lasers in Medical Science
Kate E Webster, Julian A Feller
Background: Return to sport (RTS) after anterior cruciate ligament (ACL) reconstruction is a topic of current interest. The high reinjury rates reported in younger athletes may be due in part to an early RTS. Purpose: To determine the proportion of athletes who return to level I (jumping, hard pivoting, and cutting) sport at less than 1 year after ACL reconstruction and compare return rates by age and sex. A secondary purpose was to examine whether RTS is associated with some commonly used outcome criteria...
August 2018: Orthopaedic Journal of Sports Medicine
Benoit Pétré, André Scheen, Olivier Ziegler, Anne-Françoise Donneau, Nadia Dardenne, Eddy Husson, Adelin Albert, Michèle Guillaume
While weight-loss expectations have primarily been studied in people enrolled in weight-loss programs, the present study explores patient expectations about weight-loss and identifies related determinants in a large, non-clinical population. 3916 volunteers (age > 18 years) participated in 2012 in a community-based survey in the French-speaking region of Belgium. Participants were asked to define "dream", "goal", "happy", "acceptable", and "disappointed" weights...
December 2018: Preventive Medicine Reports
Antoine Thiery-Vuillemin, Mads Hvid Poulsen, Edouard Lagneau, Guillaume Ploussard, Alison Birtle, Louis-Marie Dourthe, Dominique Beal-Ardisson, Elias Pintus, Redas Trepiakas, Laurent Antoni, Martin Lukac, Suzy Van Sanden, Geneviève Pissart, Alison Reid
Introduction: Abiraterone acetate plus prednisone (AAP) and enzalutamide (ENZ) are commonly prescribed for metastatic castration-resistant prostate cancer (mCRPC). Data comparing their effects on patient-reported outcomes (PROs) from routine clinical practice are limited. Methods: AQUARiUS (NCT02813408) is an ongoing, two-cohort, prospective, observational, non-randomised, multicentre, phase IV European study assessing the effects of AAP and ENZ on PROs in 211 patients with mCRPC over 12 months...
2018: ESMO Open
Marie Kjærgaard Larsen, Thomas Kofod, Ann-Eva Christiansen, Thomas Starch-Jensen
Objectives: The objective of the present systematic review was to test the hypothesis of no difference in facial swelling, pain and trismus after surgical removal of mandibular third molar with different dosages of corticosteroids and administration routes. Material and Methods: A MEDLINE (PubMed), Embase database and Cochrane Library search in combination with a hand-search of relevant journals was conducted by including randomized controlled trials published in English until 1st December 2017...
April 2018: Journal of Oral & Maxillofacial Research
John Daniel A Ramos, Elleen L Cunanan, Lauro L Abrahan, Marc Denver A Tiongson, Felix Eduardo R Punzalan
Background: Symptoms of mitral stenosis (MS) are worsened during tachycardia and exercise. Beta-blockers are used in controlling heart rate (HR) in MS, resulting in symptom improvement, but coming with significant side effects. Ivabradine has a selective action on the sinus node devoid of the usual side effects of beta-blockers. Small studies have recently investigated the role of ivabradine in MS in sinus rhythm. Our aim was to determine the efficacy of ivabradine, compared to beta-blockers, in terms of exercise duration, maximum HR achieved, resting HR, mean gradient, and working capacity among patients with MS in sinus rhythm...
August 2018: Cardiology Research
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