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transcatheter aortic valve replacement

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https://www.readbyqxmd.com/read/29040038/ferumoxytol-enhanced-mr-angiography-for-vascular-access-mapping-before-transcatheter-aortic-valve-replacement-in-patients-with-renal-impairment-a-step-toward-patient-specific-care
#1
Kim-Lien Nguyen, John M Moriarty, Adam N Plotnik, Olcay Aksoy, Takegawa Yoshida, Richard J Shemin, William M Suh, J Paul Finn
Purpose To assess the technical feasibility of the use of ferumoxytol-enhanced (FE) magnetic resonance (MR) angiography for vascular mapping before transcatheter aortic valve replacement in patients with renal impairment. Materials and Methods This was an institutional review board-approved and HIPAA-compliant study. FE MR angiography was performed at 3.0 T or 1.5 T. Unenhanced computed tomographic (CT) images were used to overlay vascular calcification on FE MR angiographic images as composite fused three-dimensional data...
October 16, 2017: Radiology
https://www.readbyqxmd.com/read/29033504/procedural-characteristics-and-outcomes-of-transcatheter-aortic-valve-implantation-a-single-center-experience-of-the-first-100-inoperable-or-high-surgical-risk-patients-with-severe-aortic-stenosis
#2
Ying-Hwa Chen, Hsiao-Huang Chang, Po-Lin Chen, Zen-Chung Weng, I-Ming Chen, Hsin-Bang Leu, Chun-Yang Huang, Su-Man Lin, Mei-Han Wu
BACKGROUND: This is the first study of a Taiwanese population reporting transcatheter aortic valve implantation (TAVI) outcomes of the first 100 cases from a single center offering two different transcatheter heart valve technologies via six types of approaches. We herein report the 30-day and one-year outcomes in our first 100 TAVI patients at Taipei Veterans General Hospital. METHODS: From May 2010 to April 2016, 100 consecutive patients with severe aortic stenosis (AS) who were considered unsuitable or at high risk for surgical aortic valve replacement underwent TAVI...
July 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29033387/survival-and-cause-of-death-after-transcatheter-aortic-valve-replacement-as-compared-to-an-age-and-sex-matched-background-population
#3
Marie Theut, Julie B Thygesen, Ole De Backer, Lars Søndergaard
AIMS: This study aimed to assess survival and causes of death in a real-world TAVR population as compared to an age- and sex-matched background population. METHODS AND RESULTS: Each aortic stenosis (AS) patient treated with TAVR in Eastern Denmark between 2007 and 2014 (n=617) was matched with 25 age- and sex-matched controls (n=15,425) randomly drawn from the general Danish population. In the total TAVR population, early mortality (≤90 days) was significantly higher (hazard ratio [HR] 3...
October 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29030340/microrna-206-correlates-with-left-ventricular-function-after-transcatheter-aortic-valve-implantation-tavi
#4
Jan A Kleeberger, Jonas Neuser, David de Gonzalo-Calvo, Tibor Kempf, Johann Bauersachs, Thomas Thum, Julian D Widder
Transcatheter aortic valve implantation (TAVI) is the method of choice in patients with high risk or contraindications for conventional aortic valve replacement. However, it is not well understood which parameters predict the overall cardiac function post- procedurally. MicroRNAs (miRNA/ miR) are small non-coding RNA molecules that repress gene expression by different mechanisms and can also be detected in the blood. Recent studies have shown that miRNAs detected in the blood may serve as sensitive and specific biomarkers in various diseases, therefore we examined the levels of different microRNAs in the serum of patients undergoing TAVI...
October 13, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29029105/comparative-performance-of-transcatheter-aortic-valve-in-valve-implantation-versus-conventional-surgical-redo-aortic-valve-replacement-in-patients-with-degenerated-aortic-valve-bioprostheses-systematic-review-and-meta-analysis
#5
Miroslaw Gozdek, Giuseppe Maria Raffa, Piotr Suwalski, Michalina Kolodziejczak, Lech Anisimowicz, Jacek Kubica, Eliano Pio Navarese, Mariusz Kowalewski
The objective of this report was to directly compare, by means of a systematic review and meta-analysis, redo surgical aortic valve replacement (re-sAVR) with valve-in-valve transcatheter aortic valve implantation (ViV TAVI) for patients with failed degenerated aortic bioprostheses. Multiple databases were screened for all available reports comparing ViV TAVI with re-sAVR in patients with failing degenerated aortic bioprostheses. The primary outcome was all-cause mortality determined from the longest available survival data...
September 8, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29029058/inter-ethnic-differences-in-valve-morphology-valvular-dysfunction-and-aortopathy-between-asian-and-european-patients-with-bicuspid-aortic-valve
#6
William K F Kong, Madelien V Regeer, Kian K Poh, James W Yip, Philippe J van Rosendael, Tiong C Yeo, Edgar Tay, Vasileios Kamperidis, Enno T van der Velde, Bart Mertens, Nina Ajmone Marsan, Victoria Delgado, Jeroen J Bax
Background: Transcatheter aortic valve replacement (TAVR) has been shown safe and feasible in patients with bicuspid aortic valve (BAV) morphology. Evaluation of inter-ethnic differences in valve morphology and function and aortic root dimensions in patients with BAV is important for the worldwide spread of this therapy in this subgroup of patients. Comparisons between large European and Asian cohorts of patients with BAV have not been performed, and potential differences between populations may have important implications for TAVR...
October 6, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29024382/comparison-of-outcomes-with-surgical-cut-down-versus-percutaneous-transfemoral-transcatheter-aortic-valve-replacement-tavr-transfemoral-access-comparisons-between-surgical-cut-down-and-percutaneous-approach
#7
Brandon C Drafts, Charles H Choi, Kunal Sangal, Michael W Cammarata, Robert J Applegate, Sanjay K Gandhi, Edward H Kincaid, Neal Kon, David X Zhao
OBJECTIVES: The objective is to compare the short-term (30 days) and late (12 months) vascular adverse events in patients undergoing transfemoral (TF)-transcatheter aortic valve replacement (TAVR) by surgical cut-down (SC) vs. percutaneous (PC) approaches. BACKGROUND: Programs continue to utilize both approaches in TF-TAVR. There are limited data comparing outcomes by SC vs. PC approaches and long-term effects of endovascular intervention facilitated hemostasis on late vascular adverse events...
October 10, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29024080/randomized-comparison-of-balloon-aortic-valvuloplasty-performed-with-or-without-rapid-cardiac-pacing-the-pacing-versus-no-pacing-pnp-study
#8
Gianni Dall'Ara, Antonio Marzocchi, Nevio Taglieri, Carolina Moretti, Giulio Rodinò, Matteo Chiarabelli, Paolo Bottoni, Cinzia Marrozzini, Maria Rita Sabattini, Maria-Letizia Bacchi-Reggiani, Claudio Rapezzi, Francesco Saia
OBJECTIVES: To compare the effectiveness and safety of balloon aortic valvuloplasty (BAV) performed with or without rapid ventricular pacing (RP). BACKGROUND: BAV technique is poorly standardized. METHODS: One hundred consecutive patients were randomly assigned 1:1 between BAV performed with or without RP. Exclusion criteria were an immediate indication for surgical or transcatheter aortic valve replacement, presentation in cardiogenic shock or pulmonary edema refractory to medical stabilization...
October 11, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29021275/impact-of-coronary-artery-disease-on-30-day-and-1-year-mortality-in%C3%A2-patients-undergoing-transcatheter-aortic-valve-replacement-a%C3%A2-meta-analysis
#9
REVIEW
Kesavan Sankaramangalam, Kinjal Banerjee, Krishna Kandregula, Divyanshu Mohananey, Akhil Parashar, Brandon M Jones, Yash Jobanputra, Stephanie Mick, Amar Krishnaswamy, Lars G Svensson, Samir R Kapadia
BACKGROUND: The impact of coronary artery disease (CAD) on outcomes after transcatheter aortic valve replacement (TAVR) is understudied. Literature on the prognostic role of CAD in the survival of patients undergoing TAVR shows conflicting results. This meta-analysis aims to investigate how CAD impacts patient survival following TAVR. METHODS AND RESULTS: We completed a comprehensive literature search of Embase, MEDLINE, and the Cochrane Library, and included studies reporting outcome of TAVR based on CAD status of patients for the analysis...
October 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29020413/incidence-predictors-and-clinical-outcomes-of-coronary-obstruction-following-transcatheter-aortic-valve-replacement-for-degenerative-bioprosthetic-surgical-valves-insights-from-the-vivid-registry
#10
Henrique B Ribeiro, Josep Rodés-Cabau, Philipp Blanke, Jonathon Leipsic, Jong Kwan Park, Vinayak Bapat, Raj Makkar, Matheus Simonato, Marco Barbanti, Joachim Schofer, Sabine Bleiziffer, Azeem Latib, David Hildick-Smith, Patrizia Presbitero, Stephan Windecker, Massimo Napodano, Alfredo G Cerillo, Mohamed Abdel-Wahab, Didier Tchetche, Claudia Fiorina, Jan-Malte Sinning, Mauricio G Cohen, Mayra E Guerrero, Brian Whisenant, Fabian Nietlispach, José Honório Palma, Luis Nombela-Franco, Arend de Weger, Malek Kass, Fabio Sandoli de Brito, Pedro A Lemos, Ran Kornowski, John Webb, Danny Dvir
Aims: There are limited data on coronary obstruction following transcatheter valve-in-valve (ViV) implantation inside failed aortic bioprostheses. The objectives of this study were to determine the incidence, predictors, and clinical outcomes of coronary obstruction in transcatheter ViV procedures. Methods and results: A total of 1612 aortic procedures from the Valve-in-Valve International Data (VIVID) Registry were evaluated. Data were subject to centralized blinded corelab computed tomography (CT) analysis in a subset of patients...
August 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29020347/transcatheter-aortic-valve-implantation-in-lower-risk-patients-what-is-the-perspective
#11
Giuseppe Tarantini, Luca Nai Fovino, Bernard J Gersh
In the last decade, transcatheter aortic valve implantation (TAVI), a disruptive technology, has revolutionized the therapy of symptomatic severe aortic stenosis, and current guidelines state that the recommendations for TAVI and surgical aortic valve replacement (SAVR) are equivalent in patients at high-risk. Increased operator experience, technical advances in the new generation of transcatheter heart valves (THV) and excellent TAVI results in recently published randomized controlled trials have led to the expansion of TAVI indication as an alternative to SAVR in intermediate-risk subjects, given appropriate patient selection...
August 24, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29020333/thrombo-embolic-prevention-after-transcatheter-aortic-valve-implantation
#12
Pascal Vranckx, Stephan Windecker, Robert C Welsh, Marco Valgimigli, Roxana Mehran, George Dangas
Transcatheter aortic valve implantation (TAVI) has emerged as a valuable treatment alternative to surgical aortic valve replacement among patients with symptomatic aortic stenosis at increased surgical risk. The rapid technological evolution from early to current-generation TAVI systems with low-profile delivery catheters, bioprosthetic valves with proven midterm durability, and improved positioning and retrieval features have made important contributions to the widespread clinical use of this minimal invasive therapy...
July 25, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29019612/unveiling-transthyretin-cardiac-amyloidosis-and-its-predictors-among-elderly-patients-with-severe-aortic-stenosis-undergoing-transcatheter-aortic-valve-replacement
#13
Adam Castaño, David L Narotsky, Nadira Hamid, Omar K Khalique, Rachelle Morgenstern, Albert DeLuca, Jonah Rubin, Codruta Chiuzan, Tamim Nazif, Torsten Vahl, Isaac George, Susheel Kodali, Martin B Leon, Rebecca Hahn, Sabahat Bokhari, Mathew S Maurer
Aims: Transthyretin cardiac amyloidosis (ATTR-CA) has been reported in patients with aortic stenosis (AS) but its prevalence and phenotype are not known. We examine elderly patients with severe symptomatic AS undergoing transcatheter aortic valve replacement (TAVR) and determine the prevalence and phenotype of ATTR-CA non-invasively. Methods and results: We performed technetium-99m pyrophosphate (99mTc-PYP) cardiac scintigraphy prospectively on patients who underwent TAVR, to screen for ATTR-CA...
October 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29017405/outcomes-of-transcatheter-aortic-valve-replacement-for-bicuspid-aortic-stenosis-a-systematic-review-of-existing-literature
#14
Samir V Patel, Rajesh Sonani, Vikas Singh, Palak Patel, Apurva Badheka
Patients with bicuspid aortic valve (BAV) have traditionally been excluded from large randomized clinical trials involving transcatheter aortic valve replacements (TAVR). Technical enhancements, availability of new generation devices and improved outcomes have led to a marked increase in TAVR volume across the world including off label use in patients with BAV stenosis. Areas covered: In this manuscript, we have reviewed the currently available data regarding safety, efficacy, and outcomes of TAVR in patients with BAV stenosis...
October 10, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28994687/two-episodes-of-cardiac-tamponade-in-the-same-patient-from-removing-pacing-wires-and-a-pericardial-drain-a-case-report
#15
Rekha Suthar, Osman Nawazish Salaria, Carolina De La Cuesta, Omar Viswanath
A patient presented for an elective transcatheter aortic valve replacement with temporary transvenous pacing (TVP) wires placement per protocol. On postoperative day 1, the patient remained stable, so the wires were subsequently removed, after which the patient acutely decompensated, with transthoracic echocardiography revealing pericardial effusion. Emergent pericardiocentesis was performed, and a pericardial drain was placed. Three days later, the drain was removed; again, the patient acutely decompensated, requiring another emergent pericardiocentesis...
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28992963/transapical-transcatheter-aortic-valve-replacement-with-a-novel-transcatheter-aortic-valve-replacement-system-in-high-risk-patients-with-severe-aortic-valve-diseases
#16
Liming Zhu, Yingqiang Guo, Wei Wang, Huan Liu, Ye Yang, Lai Wei, Chunsheng Wang
OBJECTIVES: The clinical experience of a novel transapical transcatheter aortic valve replacement system, the J-Valve (JC Medical Inc, Burlingame, Calif), in high-risk patients with severe aortic valve diseases is limited. METHODS: A total of 107 high-risk patients (mean age, 74.4 ± 5.2 years) underwent transcatheter aortic valve replacement with the J-Valve from March 2014 to July 2015, which included 63 patients with aortic stenoses and 44 patients with aortic regurgitation...
September 15, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28990736/hospital-outcomes-of-transcatheter-versus-surgical-aortic-valve-replacement-in-female-in-the-united-states
#17
Tomo Ando, Emmanuel Akintoye, Tesfaye Telila, Alexandros Briasouolis, Hisato Takagi, Theodore Schreiber, Luis Afonso, Cindy L Grines
OBJECTIVES: To assess the in-hospital mortality and complications in female between transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR). BACKGROUND: Female is one of the risk factors for increased adverse events in cardiac surgery. METHODS AND RESULTS: Nationwide Inpatient Sample database was queried from 2011 to 2014 for patients who underwent TAVR or SAVR in female patients. The primary endpoint was in-hospital all-cause mortality and second endpoints were perioperative complications...
October 9, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28990344/treating-of-aortic-valve-stenosis-in-real-life-a-multifaceted-decision-making-challenge
#18
EDITORIAL
Marcelo Franken, Pedro A Lemos
In this issue of CCI, Vejpongsa and coworkers showed that TAVR represented 20.4% of all aortic valve replacements performed in elderly patients from 21 US states in the year 2013. Patients treated with SAVR or TAVR largely overlapped in their baseline characteristics, indicating that both modalities concur in everyday life. One out of six patients was readmitted within 30 days, with no significant differences between the TAVR and SAVR in propensity score analysis. One may ask: since the indications of transcatheter and surgical treatments are interchanged for many cases, and the global results look similar, how to finally select the best therapeutic option for an individual case? Would the results be the same if patient-reported outcomes and experiences, such as pain and analgesic use, time to return to routine activities, or quality of life scores were measured? Combining traditional and patient-reported outcomes, in relation to costs, is the optimal approach to assess value in healthcare...
October 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28990342/post-tavr-aortogram-transform-it-into-a-modern-tool-for-prognosis-and-efficiency
#19
EDITORIAL
Pradeep K Yadav, Ian C Gilchrist
Video densitometry after aortography can provide objective assessment of aortic regurgitation post-transcatheter aortic valve replacement (TAVR) Contrast density ratio between the left ventricular outflow track and proximal aorta (LVOT-AR) of >0.17 suggests greater than mild aortic insufficiency and correlates with echo findings LVOT-AR of >0.17 is associated with higher 30-day and 1-year mortality.
October 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28988450/feasibility-of-coronary-angiography-and-percutaneous-coronary-intervention-after-transcatheter-aortic-valve-replacement-using-a-medtronic%C3%A2-self-expandable-bioprosthetic-valve
#20
Wah Wah Htun, Cindy Grines, Theodore Schreiber
BACKGROUND AND OBJECTIVE: With aging, the progression of atherosclerosis in the coronary arteries is expected. The Medtronic™ self-expandable aortic bioprosthetic valve is deployed in the supra-annular position, and it has been challenging to selectively engage coronary arteries post-transcatheter aortic valve replacement (TAVR) even though there are diamond-shaped spaces in the mesh frame within the valve. Given the scarcity of data, we analyzed angiographic and clinical data from all patients requiring coronary angiography (CA) or intervention post-TAVR...
October 8, 2017: Catheterization and Cardiovascular Interventions
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