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https://www.readbyqxmd.com/read/29455427/variation-in-cardiac-markers-and-electrocardiographic-alterations-in-young-calves-naturally-infected-with-bovine-tropical-theileriosis
#1
Kapil Kumar Gupta, Mukesh Srivastava, Vikrant Sudan, Shanker Kumar Singh, Soumen Choudhury, Daya Shanker
The present study was designed to assess the deleterious effects of bovine tropical theileriosis on the cardiovascular system and the consequent myocardial involvement in young calves. Myocardial effects in parasitic diseases are often neglected. Hemolytic anemia, associated secondary hypoxia, and vasculitis are cardinal features of bovine theileriosis. In the present study, electrocardiogram (ECG) alongside serum cardiac troponin I (cTnI) and creatinine phosphokinase-myocardial band (CPK-MB) concentrations were analyzed in infected, treated, and control groups of young calves...
February 17, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29440244/acute-rheumatic-fever-presenting-as-complete-heart-block-report-of-an-adolescent-case-and-review-of-literature
#2
Sridharan Umapathy, Anita Saxena
A 14-year-old boy suffering from chronic rheumatic heart disease came to the emergency department with recurrent episodes of presyncope and syncope. He was found to have complete heart block (CHB) and required temporary pacemaker insertion. Further workup revealed that CHB was secondary to acute rheumatic carditis. His atrioventricular (AV) conduction abnormalities recovered in a stepwise fashion over 5 days while he was being treated with corticosteroids, without the need for permanent pacemaker insertion...
February 11, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29435789/chronic-right-ventricular-pacing-in-the-heart-failure-population
#3
REVIEW
Justin Gould, Benjamin Sieniewicz, Bradley Porter, Baldeep Sidhu, Christopher A Rinaldi
PURPOSE OF REVIEW: We review the trials that have demonstrated potentially harmful effects from right ventricular (RV) apical pacing as well as reviewing the evidence of alternative RV pacing sites and cardiac resynchronization therapy (CRT) for patients who have heart failure and atrioventricular (AV) block. RECENT FINDINGS: The role of CRT in patients with AV block and impaired left ventricular function remains an important consideration. The BLOCK HF trial demonstrated better outcomes with CRT pacing over RV pacing in patients with left ventricular systolic dysfunction (LVSD) and AV block who were expected to have a high RV pacing burden, but failed to demonstrate a mortality benefit...
February 12, 2018: Current Heart Failure Reports
https://www.readbyqxmd.com/read/29424197/pregabalin-induced-first-degree-atrioventricular-block-in-a-young-patient-treated-for-pain-from-extrapulmonary-tuberculosis
#4
Alessandra Schiavo, Francesca M Stagnaro, Andrea Salzano, Alberto M Marra, Emanuele Bobbio, Pietro Valente, Simona Grassi, Martina Miniero, Michele Arcopinto, Margherita Matarazzo, Raffaele Napoli, Antonio Cittadini
Pregabalin, widely used in the treatment of several pain disorders, is usually well tolerated. Uncommonly, the drug may induce cardiac side effects, rarely prolongation of the PR interval. The latter has never been described in patients with healthy heart or normal renal function. We characterize a unique case of a young man with extrapulmonary tuberculosis and no detectable or known cardiac or kidney diseases, treated with pregabalin to control the severe pain due to the involvement of the spinal cord by the tuberculosis, showing an atrioventricular (AV) block due to pregabalin administration...
September 28, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/29416210/assesment-of-rhythm-disorders-in-classical-and-nonclassical-mitral-valve-prolapse
#5
Enisa Hodzic
Introduction: Mitral Valve Prolapse (MVP) is the most common cardiac valve pathology of to day. Aim of article was to identify the types and frequency of potentially malignant arrhythmia and atrial brillation in patients with MVP, to determine the differences in these arrhythmias between classical and non-classical MVP, to evaluate the correlation of potentially malignant arrhythmia and atrial fibrillation with MVP with possible clinical complications of arrhythmogenic sudden cardiac death and potential risk of thromboembolic vascular incident...
February 2018: Medical Archives
https://www.readbyqxmd.com/read/29387113/magnesium-sulfate-protects-the-heart-against-carbon-monoxide-induced-cardiotoxicity-in-rats
#6
Kaveh Tabrizian, Hamideh Khodayari, Ramin Rezaee, Hosseinali Jahantigh, Gholamreza Bagheri, Konstantinos Tsarouhas, Mahmoud Hashemzaei
Carbon monoxide (CO), a toxic gas produced via incomplete fossil fuel combustion, has several poisonous effects in the heart including induction of necrosis, apoptosis, and electrocardiogram (ECG) changes. Magnesium sulfate (MS) is a drug with cardioprotective effects especially when used after ischemia/reperfusion. In the current study, we aimed to evaluate MS cardioprotective effects following CO poisoning. Animals were exposed to CO 3000 ppm for 1 h and immediately after the exposure period and on the next 4 days (a total of 5 consecutive doses given on a daily basis), MS (75, 150 and 300 mg/kg) was injected intraperitoneally (i...
February 2018: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29344737/the-125th-anniversary-of-the-his-bundle-discovery
#7
REVIEW
Georg H von Knorre
In 1893, Wilhelm His Jr. was the first to describe the AV (atrioventricular) bundle of the vertebrate heart, which now bears his name. Moreover, prior to the turn of the century, W. His Jr. had proved the function of the AV bundle by transection experiments in animals, and had interpreted Adams Stokes disease as heart block due to pathological changes within the bundle. In this way, he was ahead of his time. While clinical interest was limited to the bundle as the location of an AV block in the first half of the 125 years, it has gained attractiveness since then as a target of diagnostic and therapeutic procedures...
January 17, 2018: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29341176/different-responses-of-supraventricular-tachycardia-with-2-1-av-block-to-consecutive-premature-ventricular-contractions
#8
Svetoslav Kurtev, Cristina Valduva, László Sághy, Robert Pap
A 52-year old female was admitted with complaints of palpitations for two years. The transthoracic echocardiography and electrocardiogram were both normal at the time of admission. We performed an electrophysiology study where the baseline intervals were in normal range. During burst atrial pacing we observed HV prolongation (HV = 80 ms) and infra-Hisian block. This article is protected by copyright. All rights reserved.
January 16, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29325979/an-unusual-case-of-complete-atrioventricular-block-causing-takotsubo-syndrome
#9
Abhishek Rathore, Bharatraj Banavalikar, Jayaprakash Shenthar, Debashish Acharya, Javed Parvez, Kikkeri Hemanna Setty Srinivasa
Complete atrioventricular (AV) block in association with Takotsubo syndrome (TS) has been well recognized, but the cause and effect relationship has not been elucidated. We describe a 78-year-old female who presented with complete AV block but one week later developed new-onset, diffuse T-wave inversions, QT prolongation, and acceleration of junctional escape rate. Left ventriculogram revealed features typical of TS. One year after permanent pacemaker implantation, complete AV block persisted despite the reversal of wall motion defects implying that conduction abnormality was the trigger of TS rather than its consequence...
January 9, 2018: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29275956/lyme-carditis-early-occurrence-and-prolonged-recovery
#10
Jianwei Fu Md, Luna Bhatta
Lyme carditis is an uncommon manifestation of early disseminated Lyme disease. This case illustrates a 66-year-old male with complaints of fatigue, myalgias, and fever after a tick bite 3days earlier. A large erythema migrans was found on the chest wall. Initial electrocardiogram showed sinus rhythm with second degree 2:1 atrioventricular (AV) block, which progressed to intermittent complete AV block rapidly. He was treated with intravenous ceftriaxone. Over the course of 2-weeks of antibiotic therapy, the intermittent high-grade AV block improved slowly and progressively...
December 14, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29260369/predictors-of-right-ventricular-pacing-and-pacemaker-dependence-in-transcatheter-aortic-valve-replacement-patients
#11
Esseim Sharma, Antony F Chu
PURPOSE: Transcatheter aortic valve replacement (TAVR) is an increasingly prevalent therapy in patients with severe symptomatic aortic stenosis. Conduction disturbances requiring permanent pacemaker (PPM) implantation are a known complication of TAVR. This study investigated the progression of cardiac conduction disease in the post-TAVR pacemaker population and identified predictors of post-TAVR right ventricular (RV) pacing dependence. METHODS: Prospectively collected echocardiographic, ECG, and PPM interrogation data of 262 consecutive patients who underwent TAVR with placement of a balloon-expandable valve at one institution from March 2012 to October 2016 were analyzed...
December 19, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29259045/risk-of-cardiac-rhythm-disturbances-and-aortic-regurgitation-in-different-spondyloarthritis-subtypes-in-comparison-with-general-population-a-register-based-study-from-sweden
#12
Karin Bengtsson, Helena Forsblad-d'Elia, Elisabeth Lie, Eva Klingberg, Mats Dehlin, Sofia Exarchou, Ulf Lindström, Johan Askling, Lennart T H Jacobsson
OBJECTIVES: To describe the incidence of atrioventricular (AV) block II-III, atrial fibrillation (AF), pacemaker implantation (PM) and aortic regurgitation in patients with ankylosing spondylitis (AS), undifferentiated spondyloarthritis (uSpA) and psoriatic arthritis (PsA) compared with the general population (GP) and with each other. METHODS: A prospective nationwide study with cohorts of patients with AS (n=6448), PsA (n=16 063) and uSpA (n=5190) and a GP (n=2 66 435) cohort, identified in 2001-2009 in the Swedish National Patient and Population registers...
December 19, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29250237/resolution-of-av-block-after-ablation-for-atrial-fibrillation
#13
Matthew Glassy, Nayereh Pezeshkian, Yingbo Yang, Uma N Srivatsa
We report a case with complete atrioventricular block (AVB) present both during sinus rhythm and with atrial fibrillation (AF). He had declined pacemaker placement and opted for ablation for the symptomatic AF. He underwent staged hybrid approach with video-assisted thoracoscopic surgical maze (VATS) followed by endocardial ablation. VATS included ganglionic plexi cauterization. One month after the endocardial procedure, he had complete resolution of AF and AVB and remains so at 18 months follow up. We discuss possible abolition of vagal input for this improvement in AV conduction...
August 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250217/atrial-fibrillation-is-associated-with-increased-pacemaker-implantation-rates-in-the-placement-of-aortic-transcatheter-valve-partner-trial
#14
Angelo B Biviano, Tamim Nazif, Jose Dizon, Hasan Garan, Mark Abrams, Jessica Fleitman, Dua Hassan, Samir Kapadia, Vasilis Babaliaros, Ke Xu, Josep Rodes-Cabau, Wilson Y Szeto, William F Fearon, Danny Dvir, Todd Dewey, Mathew Williams, Steven Kindsvater, Michael J Mack, John G Webb, D Craig Miller, Craig R Smith, Martin B Leon, Susheel Kodali
Atrial fibrillation (AF) is associated with worse outcomes in many cardiovascular diseases. There are few data examining pacemaker implantation rates and indications in patients with AF who undergo transcatheter aortic valve replacement (TAVR). To examine the impact of AF on the incidence of and indications for pacemakers in patients undergoing TAVR, we evaluated data of 1723 patients without pre-existing pacemakers who underwent TAVR in the Placement of AoRTic TraNscathetER Valve (PARTNER) trial. Permanent pacemaker implantation rates and indications were compared in groups based on baseline and discharge heart rhythm: sinus rhythm (SR) vs...
June 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29240293/transvenous-pacemaker-implantation-after-the-bidirectional-glenn-operation-for-patients-with-complex-congenital-disease
#15
Danielle E Harake, Kevin M Shannon, Jamil A Aboulhosn, Jeremy P Moore
INTRODUCTION: The bidirectional Glenn operation for congenital heart disease produces anatomical constraints to conventional transvenous pacemaker implantation. An iliac approach, although not previously described in this population, is potentially a preferable alternative to a thoracotomy for epicardial pacing. METHODS AND RESULTS: A single-center retrospective review was performed for all patients that underwent transvenous pacemaker implantation following the bidirectional Glenn operation with partial biventricular repair...
December 14, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29229209/randomized-double-blind-placebo-controlled-dose-escalation-study-investigation-of-the-safety-pharmacokinetics-and-antihyperalgesic-activity-of-l-4-chlorokynurenine-in-healthy-volunteers
#16
Mark Wallace, Alexander White, Kathy A Grako, Randal Lane, Allen Jo Cato, H Ralph Snodgrass
BACKGROUND AND AIMS: Neuropathic pain is a significant medical problem needing more effective treatments with fewer side effects. Overactive glutamatergic transmission via N-methyl-d-aspartate receptors (NMDARs) are known to play a role in central sensitization and neuropathic pain. Although ketamine, a NMDAR channel-blocking antagonist, is often used for neuropathic pain, its side-effect profile and abusive potential has prompted the search for a safer effective oral analgesic. A novel oral prodrug, AV-101 (l-4 chlorokynurenine), which, in the brain, is converted into one of the most potent and selective GlyB site antagonists of the NMDAR, has been demonstrated to be active in animal models of neuropathic pain...
October 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29202647/swallow-presyncope-in-an-athletic-patient-caused-by-third-degree-atrioventricular-block
#17
Axel Van Damme, Tine De Backer, Philippe Vanderheeren
Introduction Swallow syncope is a neurally mediated syncope. Multiple causes have been described in literature. A rare cause is arrhythmias. Only a limited amount of cases present the association of swallow syncope and third degree AV-block. Case presentation A 39-year-old man presented with episodes of presyncope while eating. Further medical history, physical examination, resting 12-lead ECG, cyclo-ergometry, transthoracic echocardiography and MRI of the heart were normal. 24 h Holter monitoring demonstrated high-grade third-degree atrioventricular (AV) block...
December 5, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29194653/electrophysiological-markers-predicting-impeding-av-block-during-ablation-of-atrioventricular-nodal-re-entry-tachycardia
#18
Nikolaos Fragakis, Lydia Krexi, Panagiota Kyriakou, Melani Sotiriadou, Charalambos Lazaridis, Athanasios Karamanolis, Panagiotis Dalampyras, Stelios Tsakiroglou, Vassilios Skeberis, Dimitrios Tsalikakis, Vassilios Vassilikos
BACKGROUND: Radiofrequency (RF) ablation of the slow pathway (SP) in atrioventricular nodal reentry tachycardia (AVNRT) is occasionally complicated with atrioventricular block (AVB) often predicted by junctional beats (JB) with loss of ventriculo-atrial (VA) conduction. METHODS: We analysed retrospectively 153 patients undergoing ablation of SP for typical AVNRT. Patients were divided into two age groups: 127 ≤70 years and 26 > 70 years. We analysed the interval between the atrial electrogram in the His-bundle position and the distal ablation catheter [A(H)-A(RFd)] and the proximal coronary sinus catheter [A(RFd)-A(CS)] before RF applications with and without JB...
November 30, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29186415/atrioventricular-dromotropathy-evidence-for-a-distinctive-entity-in-heart-failure-with-prolonged-pr-interval
#19
Floor C W M Salden, Valentina Kutyifa, Martin Stockburger, Frits W Prinzen, Kevin Vernooy
Heart failure (HF) is often accompanied by atrioventricular (AV) conduction disturbance, represented by prolongation of the PR interval on the electrocardiogram. Studies suggest that PR prolongation exists in at least 10% of HF patients, and it seems more prevalent in the presence of prolonged QRS duration. A prolonged PR interval may result in elevated left ventricular (LV) end-diastolic pressure, diastolic mitral regurgitation, and reduced LV pump function. This seems especially the case in patients with heart disease, in whom it is associated with an increased risk for atrial fibrillation, advanced AV heart block, HF, and death...
November 24, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29184615/mobitz-type-ii-atrioventricular-block-following-tramadol-and-fentanyl-in-a-patient-with-acute-coronary-syndrome-and-systolic-heart-failure
#20
Alaa A Rahhal, Amer H Aljundi, Abdulrahman Arabi
Serotonin syndrome is a potentially fatal condition allied with increased serotonergic activity in the central nervous system. There are published data reporting serotonin syndrome induced by either tramadol or fentanyl in combination with selective serotonin reuptake inhibitors in adult patients; however, there are no reports of serotonin syndrome resulting from the combination of tramadol and fentanyl. We report a case of a 52-year-old woman who was admitted to cardiology service and who developed Mobitz Type II atrioventricular (AV) block after administration of oral tramadol and intravenous fentanyl...
July 2017: Heart Views: the Official Journal of the Gulf Heart Association
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