keyword
https://read.qxmd.com/read/32884618/not-your-average-skin-cancer-a-rare-case-of-pilomatrix-carcinoma
#21
Christopher White, Maheera Farsi, David Esguerra, Richard Miller
Pilomatrix carcinoma is a rare malignancy stemming from aberrant proliferation of matrical cells found in developing hair. This neoplasm demonstrates a bimodal age distribution and a proclivity for developing on the head or neck. Clinically, a firm, painless, violaceous nodule with overlying ulceration is commonly described. Pilomatrix carcinoma is considered a variable-grade malignancy that tends to be locally aggressive, though metastatic disease occurs in 10 to 16 percent of cases. Mortality rates range from 7 to 9 percent...
June 2020: Journal of Clinical and Aesthetic Dermatology
https://read.qxmd.com/read/32190433/pilomatrix-carcinoma-of-the-antecubitum
#22
Michael D Eckhoff, Joshua Tadlock, Lisa A Kafchinski
We present the case of a 46-year-old male with atypically large left elbow pilomatrix carcinoma present for 10 years with emergent excision after developing life-threatening hemorrhage. Pilomatrix carcinoma is a dermal-based malignant tumor typically of the head and neck region. Histopathology shows islands of basaloid cells, shadow cells, and fibromyxoid fibroma. Reoccurrence is seen in 23% of cases on an average of six months after primary excision. The current standard of care is wide excision with close follow-up...
January 30, 2020: Curēus
https://read.qxmd.com/read/32077434/pilomatrix-carcinoma-a-rare-hair-cell-tumor
#23
REVIEW
Tyler Briley, John L Sobiesk, Quyen Chu
No abstract text is available yet for this article.
January 1, 2020: American Surgeon
https://read.qxmd.com/read/31833930/18f-fdg-pet-ct-findings-in-metastatic-pilomatrix-carcinoma
#24
JOURNAL ARTICLE
Tarik Sengoz, Nilufer Avci
We describe a rare case of metastatic pilomatrix carcinoma with distant metastases 10 months after diagnosis. A 37-year-old woman was diagnosed with pilomatrix carcinoma by excisional biopsy from the occipital region and referred to us for F-FDG PET/CT examinations at the time of diagnosis and 10 months after diagnosis. The first PET/CT did not show any pathological activity, whereas the second PET/CT showed multiple intensive F-FDG uptakes in the right lung parenchyma, right hemithorax pleura, liver, and bones...
December 9, 2019: Clinical Nuclear Medicine
https://read.qxmd.com/read/31756690/pilomatrix-carcinoma-of-the-right-postauricular-region-a-case-report-and-literature-review
#25
JOURNAL ARTICLE
Shabiah Martin, Jana DeJesus, Ann Jacob, Teah Qvavadze, Claudio Guerrieri, Rachel Hudacko, Thaddeus Boucree
INTRODUCTION: Pilomatrix carcinoma is a rare aggressive tumor with a high rate of local recurrence after surgical excision. Diagnosis is made by histopathology and when discovered, wide local excision has been shown to have the best results. PRESENTATION OF CASE: We report a case of a 74-year-old male incidentally found to have a large right postauricular mass and regional lymphadenopathy. The mass was biopsied and proven to be a malignant pilomatrixoma. Wide local excision and level II and III neck dissection with reconstruction using a right supraclavicular flap was performed...
2019: International Journal of Surgery Case Reports
https://read.qxmd.com/read/29863570/basal-cell-carcinoma-with-matrical-differentiation-report-of-a-new-case-in-a-renal-transplant-recipient-and-literature-review
#26
REVIEW
Jean Kanitakis, Emilie Ducroux, Pauline Hoelt, Rémi Cahen, Denis Jullien
Basal-cell carcinoma with matrical differentiation (BCC-MD) is one of the rarest pathologic variants of basal-cell carcinoma, of which 41 cases have been so far reported in detail. One of them developed in a heart-transplant recipient. We report a new case of BCC-MD occurring in a renal-transplant recipient and review the relevant literature. A 75-year-old white man who had received a renal allograft 7 years ago developed a tumor on the left temple clinically suggestive of basal-cell carcinoma. Microscopically, the tumor associated features typical of basal-cell carcinoma (basaloid lobules with peripheral palisading and clefting) and pilomatricoma (presence of shadow/ghost cells)...
August 2018: American Journal of Dermatopathology
https://read.qxmd.com/read/29693075/pilomatrix-carcinoma-of-the-nose-clinical-and-dermoscopic-presentation
#27
JOURNAL ARTICLE
Giulia Maria Ravaioli, Martina Lambertini, Massimiliano Pazzaglia, Barbara Corti, Pier Alessandro Fanti, Emi Dika
No abstract text is available yet for this article.
May 2018: JAAD Case Reports
https://read.qxmd.com/read/29687064/facial-pilomatrix-carcinomas-treated-with-mohs-micrographic-surgery
#28
Lin Xing, Sean A Marzolf, Travis Vandergriff, Rajiv I Nijhawan
No abstract text is available yet for this article.
April 2018: JAAD Case Reports
https://read.qxmd.com/read/29624700/sarcomatoid-pilomatrix-carcinoma
#29
Angel Fernandez-Flores, David S Cassarino
Pilomatrix (pilomatrical) carcinoma is a rare cutaneous adnexal tumor with matrical differentiation and recurrent and metastatic potential. Sarcomatoid pilomatrix carcinoma is a rare variant which shows a sarcomatoid component intermingling with the epithelial one. There are only 4 cases previously published. We present an additional case on the hand of a 78 year-old man which appeared as a 6 mm hyperkeratotic, focally ulcerated plaque. A shave biopsy demonstrated a dermal infiltrative neoplasm, composed of markedly atypical-appearing basaloid cells with focal necrotic/ghost cells, as well as an intimately associated population of atypical oval to spindle-shaped cells...
July 2018: Journal of Cutaneous Pathology
https://read.qxmd.com/read/29369180/primary-cutaneous-anaplastic-large-cell-lymphoma-a-case-report
#30
JOURNAL ARTICLE
Kamil Abed, Zygmunt Stopa, Marta Siewert-Gutowska
RATIONALE: Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is a rare cancer belonging to the group of primary T-cell lymphoproliferative diseases. C-ALCL is characterized by the presence of single or multiple ulcerated lesions on the skin's surface. PATIENT CONCERNS: This is the case of a 73-year-old man who reported to the Clinic of Cranio-Maxillofacial and Oral Surgery and Implantology, Medical University of Warsaw, owing to a skin tumor in the right parotideomasseteric region, initially diagnosed as discoid lupus erythematosus...
January 2018: Medicine (Baltimore)
https://read.qxmd.com/read/29200693/pilomatrix-carcinoma-masquerading-as-breast-carcinoma
#31
Trupti Pai, Shweta R Harwani, Asawari Patil, Ayushi Sahay, Tanuja Shet, Vani Parmar, Tabassum Wadasadawala, Sangeeta B Desai
Pilomatrix carcinoma is an exceedingly rare skin adnexal neoplasm derived from piliferous follicles, usually occurring in the head and neck region. Localization of this tumor in the breast is a rarity. We now report an unusual case of a 49-year-old female who presented with a palpable mass in the left breast for 2 years. Mammogram revealed a large, lobulated opacity with calcification, and positron emission tomography-computed tomography showed a metabolically active soft tissue mass measuring 15 cm involving all the quadrants of the left breast...
July 2017: Indian Journal of Medical and Paediatric Oncology
https://read.qxmd.com/read/28914451/pilomatrix-carcinoma-12-year-experience-and-review-of-the-literature
#32
REVIEW
Christopher Jones, Mark Twoon, Weiguang Ho, Mark Portelli, Bernard F Robertson, William Anderson
Pilomatrix carcinoma is a rare, locally aggressive tumor with a tendency to recur. Distant metastases have been reported, with pulmonary lesions being the most frequent manifestation. Similar to pilomatrixoma, pilomatrix carcinoma typically presents as a nontender, firm dermal swelling and is found most commonly in the head and neck region. Although pilomatrixomas and pilomatrix carcinoma are well-recognized lesions, clinically they are frequently misdiagnosed as other skin conditions. By reviewing the literature over the past 10 years, the aims of this review are to analyze the cause, clinical presentation, histopathologic features, management and outcomes of pilomatrix carcinoma amongst children and adults...
January 2018: Journal of Cutaneous Pathology
https://read.qxmd.com/read/28881180/giant-pilomatrix-carcinoma-of-the-face
#33
JOURNAL ARTICLE
Sapna Lohiya, Yeshwant B Rawal, Jasjit K Dillon
This case report describes an unusually large facial pilomatrix carcinoma (PC) in a 60-year-old man. This PC had been growing slowly for 11 months and had recently ulcerated. It measured 9 cm × 7 cm × 5 cm. Initial punch biopsy findings were inconclusive. The tumor was excised in total with 5-mm margins in a supra-superficial musculoaponeurotic system plane. The defect was reconstructed with a cervicofacial bilobed rotational advancement flap. Histopathologic findings confirmed the diagnosis of PC...
February 2018: Journal of Oral and Maxillofacial Surgery
https://read.qxmd.com/read/28451423/pilomatrix-carcinoma-more-malignant-biological-behavior-than-was-considered-in-the-past
#34
JOURNAL ARTICLE
Marios Papadakis, Eelco de Bree, Nikolaos Floros, Elpida Giannikaki, Athina Xekalou, Andreas Manios
Pilomatrix carcinoma is a very rare malignancy, with ~130 cases reported in the literature. In the past, pilomatrix carcinoma was considered to be a low-grade malignant tumor. Currently, however, its significant recurrence and metastatic potential has been well documented. Lymph node and systemic metastases are frequently observed. Wide surgical excision of the primary lesion is the principal modality of treatment, whereas adjuvant radiotherapy may be beneficial in local tumor control. Lymph node metastases may be treated surgically or with radiotherapy...
March 2017: Molecular and Clinical Oncology
https://read.qxmd.com/read/28445202/adnexal-carcinomas-treated-with-mohs-micrographic-surgery-a-comprehensive-review
#35
REVIEW
Stanislav N Tolkachjov
BACKGROUND: Adnexal carcinomas (ACs) are rare cutaneous malignancies of sweat gland or pilosebaceous origin. Optimal treatment and metastatic potential of AC are poorly defined. Mohs micrographic surgery (MMS) has been increasingly used to treat AC. OBJECTIVE: To review selected primary cutaneous AC and their treatment outcomes with MMS. MATERIALS AND METHODS: Literature review using PubMed search for articles related to primary cutaneous ACs...
October 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://read.qxmd.com/read/28261645/concurrent-pilomatrix-carcinoma-and-diffuse-large-b-cell-lymphoma
#36
JOURNAL ARTICLE
Luis Parra, Marcos Martin, María Garrido, Jose María Pedraza, Javier Palazon, Manuel Robustillo, Daniel Grandes, Emilio Lagaron
Pilomatrix carcinoma is a rare cutaneous tumor derived from follicular matrix cells. It may arise de novo or from a malignant transformation of a pilomatrixoma. The latter process has been associated with impaired immune system surveillance of the host caused by UV radiation or the onset of an underlying malignant neoplasm. We report a case of a 58-year-old man presenting with a long-standing pilomatrix carcinoma on the inner right leg after 10 years of repeated curettage of the lesion, concurrent with a high-grade B-cell lymphoma on the same extremity...
2016: Oncology and Therapy
https://read.qxmd.com/read/28031142/pilomatrix-carcinoma-mimicking-a-pigmented-basal-cell-carcinoma
#37
Jaimie B Glick, Usha Alapati, Amor Khachemoune
A 76-year-old Caucasian man presented to the dermatology clinic for evaluation of a growing lesion in his right preauricular area. He first noticed the lesion several months prior to presentation but felt it had enlarged significantly in the past month. He denied any pain, pruritus, or bleeding. His medical history was significant for melanoma of the nose treated 47 years ago, hypertension, hyperlipidemia, chronic obstructive pulmonary disease, and chronic back pain. The patient reported having the melanoma treated but was unaware of any other details concerning the lesion...
2016: Skinmed
https://read.qxmd.com/read/27824328/18f-fdg-pet-ct-in-metastatic-pilomatrix-carcinoma
#38
JOURNAL ARTICLE
Manuela Vadrucci, Laura Gilardi, Filippo Crivelli, Alberto Baroli, Giuseppe Lomuscio
We describe the FDG PET/CT findings in an exceedingly rare case of metastatic pilomatrix carcinoma (PC). A 76-year-old man, who underwent incisional biopsy of a soft-tissue mass in the frontal scalp that revealed PC, was referred for an F-FDG PET/CT scan for staging purposes. PET/CT showed areas of increased radiotracer uptake corresponding to frontal mass and unsuspected lung lesions, which were later confirmed as metastases from PC at histological analysis. Clinical condition deteriorated rapidly, and the patient died 3 months after the initial diagnosis...
December 2016: Clinical Nuclear Medicine
https://read.qxmd.com/read/27673386/metastatic-malignant-pilomatrixoma-in-an-8-year-old-girl-misdiagnosed-as-a-recurrent-pilomatrixoma
#39
JOURNAL ARTICLE
Mario N Otero, Carolina P Trujillo, Rafael Parra-Medina, Samuel D Morales
Malignant pilomatrixoma or pilomatrix carcinoma is a rare, locally aggressive malignant neoplasm, derived from the hair follicle with a high propensity for local recurrence. Only a few cases of metastatic pilomatrixoma have been described in the literature. Till date, only 17 cases have been reported in the English-language medical literature, most commonly occurring associated with local recurrence in adults. We report the first case in children of a metastatic malignant pilomatrixoma in an 8-year-old girl presenting with a recurrent pilomatrix carcinoma of the forehead with metastases in cervical and parotid lymph nodes...
March 2017: American Journal of Dermatopathology
https://read.qxmd.com/read/27408466/dermoid-cyst-of-submental-region-mimicking-pilomatricoma
#40
JOURNAL ARTICLE
P Sheshadri, T M Kalappa, B Pramod Krishna, Santhosh Kumaran, M A Lakshith Biddappa
Diagnosis of midline neck swellings may give a myriad of options, ranging from ranula, thyroglossal duct cyst, cystic hygroma, cystic lymphangioma, epidermoid, dermoid and teratoid cysts to benign or malignant neoplasms of the mucosa or salivary glands and also rare skin appendage tumours like pilomatricoma or pilomatrix carcinoma. Various pitfalls are encountered in diagnosing these midline swellings as most of the features are overlapping. Careful history and examination have to be complemented with other diagnostic aids such as conventional radiography, ultrasonography, aspiration cytology and computed tomography to arrive at a correct diagnosis...
July 2016: Journal of Maxillofacial and Oral Surgery
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