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https://www.readbyqxmd.com/read/30533207/pulmonary-alveolar-proteinosis-a-crazy-presentation-of-dyspnea
#1
Inge Raadal Skov, Elisabeth Bendstrup, Jesper Rømhild Davidsen
This case report demonstrates 44-year old man, presenting with recurring clinical pneumonias during a period of over 1 year. The patient was clinically affected with, i.a., weight loss, finger clubbing and severely reduced diffusion capacity. Repetitive chest x-rays showed bilateral and consolidating infiltrates, and a high-resolution computed tomography of the thorax (HRCT) exposed ground glass opacities superimposed on a reticular pattern as the so-called 'crazy paving' pattern. A bronchoscopic alveolar lavage revealed alveolar proteinaceous material compatible with the diagnosis pulmonary alveolar proteinosis (PAP)...
2019: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30210893/nodular-pulmonary-amyloidosis-a-manifestation-of-sj%C3%A3-gren-s-syndrome
#2
Gustavo Adolfo Gómez Correa, Jovani Osorno Serna, Manuel Felipe Cáceres Acosta, Juan David Cáceres González, Jaime Andrés Calle Ramirez, Juan Paulo Sandoval Mesa, Miguel Ignacio Roldán Pérez
Case Description: A 72-year-old woman with primary Sjögren Syndrome (SS) was diagnosed during an inpatient hospital stay with dry symptoms. The patient had respiratory and constitutional symptoms, requiring a pulmonary imaging evaluation by high-resolution computed tomography (HRCT) of the thorax. Clinical Findings: Multiple cavitary pulmonary nodules, halo sign, and focal areas of ground-glass opacity with predominance in both bases were found in the images. Complementary studies were done where a neoplastic focus was ruled out...
2018: Case Reports in Pulmonology
https://www.readbyqxmd.com/read/30172458/interstitial-lung-diseases-imaging-contribution-to-diagnosis-and-elementary-radiological-lesions
#3
REVIEW
Henda Neji, Monia Attia, Mariem Affes, Ines Baccouche, Khaoula Ben Miled-M'rad, Saoussen Hantous-Zannad
Interstitial pneumonias comprise a heterogeneous group of disorders in which a multidisciplinary approach is important for accuracy in diagnosis; indeed, one might say, even mandatory. The team of collaborators should include radiologists, because high resolution computed tomography (HRCT) of the thorax is the first, and most of times, the only imaging examination to be prescribed after chest X-ray. Elementary lesions of the interstitium can be accurately described with HRCT, inasmuch as lung windowing with sharp filtering in this technique reproduces the microscopic features of the lung...
September 2018: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/30028804/lung-ultrasound-as-a-screening-method-for-interstitial-lung-disease-in-patients-with-systemic-sclerosis
#4
Romina Isabel Hassan, Lucia I Lubertino, Maria Angeles Barth, Maria Fernanda Quaglia, Sandra Fabiana Montoya, Eduardo Kerzberg, Maria Del Carmen Binda
BACKGROUND: Patients with systemic sclerosis (SSc) undergo chest radiographs and high-resolution computed tomography (HRCT) of the thorax both for interstitial lung disease (ILD) detection and for disease progression monitoring. OBJECTIVE: The aim of this study was to assess whether lung ultrasound (LUS) is a useful screening tool for ILD in patients with SSc in comparison with HRCT. METHODS: This was a prospective cohort study carried out from December 2015 to April 2016...
July 20, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/30020040/look-closer-to-welders-lung
#5
İpek Özmen, Elif Yıldırım, Reyhan Yıldız, Hamza Ogun, Emine Aksoy, Tülay Törün, Peri Arbak, Haluk Çalışır
Introduction: Welding produces miscellaneous gases and particles that has various impact on respiratory system and long term exposure may result "welders'lung". The aim of this study is to describe the radiological findings of welders' and make an awereness for welders radilogical findings. Materials and Methods: The clinical and radiological findings of welders' who had hospital applications with respiratory symptoms between January 2010-January 2017 were evaluated retrospectively...
March 2018: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/29952960/sustained-clinical-response-after-single-course-of-rituximab-as-first-line-monotherapy-in-adult-onset-asthma-and-periocular-xanthogranulomas-syndrome-associated-with-igg4-related-disease-a-case-report
#6
Giovanni Pomponio, Diletta Olivari, Massimo Mattioli, Alessia Angeletti, Giulia Rossetti, Gaia Goteri, Armando Gabrielli
RATIONALE: IgG4-related disease (IgG4-RD) is an emerging immune-mediated disease characterized by multi-organ involvement and variable clinical behavior. PATIENT CONCERNS: We describe the case of a 50-year-old woman affected by a rare variant of IgG4-RD, characterized by eyelid xanthelasmas, adult-onset asthma and salivary and lacrimal glands enlargement. Multiple lymphadenopathies and a pulmonary mass were present at initial evaluation. INTEVENTIONS: After a single course of rituximab (2g in 2 refracted doses), an almost complete clinical remission was achieved without chronic steroid administration...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29692256/gauzoma-in-a-scleroderma-patient-following-open-heart-surgery-a-case-report
#7
Mohammadali Nazarinia, Elmira Esmaeilzadeh
INTRODUCTION: Gauzoma is an iatrogenic complication, which occurs rarely due to surgical team negligence. Depending on the sterility of the retained tissue, it can lead to life threatening surgical complications or may remain asymptomatic for many years and be detected incidentally in imaging studies. It may be mistaken as tumors or aneurysms. Thus, high clinical suspicion is needed to diagnose them in patients with past history of operation. Reporting Case: A 35 years old woman, a known case of scleroderma underwent open-heart surgery 20 years before being diagnosed as scleroderma, presented by dyspnea especially on activity...
April 22, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29173135/a-64-year-old-woman-with-interstitial-lung-disease-and-positive-antibodies-against-aminoacyl-transfer-rna-synthetases-in-the-absence-of-myositis-presentation-of-an-anti-pl-12-positive-antisynthetase-syndrome
#8
Katrien Ghysen, Mathias Leys
Introduction The antisynthetase syndrome is a rare autoimmune disease described by the presence of inflammatory myositis, interstitial lung disease and antibodies against aminoacyl-transfer RNA synthetases. Interstitial lung disease can be the only manifestation in the absence of an inflammatory myositis. Other clinical signs are Raynaud phenomenon, hyperkeratotic skin lesions, fever and inflammatory polyarthritis. Case presentation We report the case of a 64-year old woman who complained of a dry cough, progressive dyspnea and arthralgia since 2 years, with no other systemic symptoms...
October 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28667653/occurrence-of-bronchial-anthracofibrosis-in-respiratory-symptomatics-with-exposure-to-biomass-fuel-smoke
#9
Vikas Pilaniya, Shekhar Kunal, Ashok Shah
INTRODUCTION: Bronchial anthracofibrosis (BAF), confirmed bronchoscopically, is characterised by bluish-black mucosal pigmentation and distortion/narrowing of the bronchus. We investigated the occurrence of BAF in respiratory symptomatics with biomass fuel smoke exposure and evaluated its clinico-radiological attributes and impact on functional status. MATERIAL AND METHODS: Of the eighty subjects evaluated, 60 consented for fiberoptic bronchoscopy (FOB). All 60 subjects also underwent chest radiography, high resolution computed tomography (HRCT) of the thorax, complete pulmonary function testing including diffusion capacity and six-minute-walk test...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28368564/effect-of-sequential-intravenous-pulse-cyclophosphamide-azathioprine-in-systemic-sclerosis-interstitial-lung-disease-an-open-label-study
#10
Susmita Kundu, Suman Paul, K Hariprasath, Rajesh Agarwal, Saswata Ghosh, Debabani Biswas
BACKGROUND: Systemic sclerosis (SSc) is a rare connective tissue disorder of unknown aetiology. Pulmonary involvement contributes substantially to its morbidity and mortality. Treatment of pulmonary disease due to SSc remains unsatisfactory. We examined the effect of sequential six-month intravenous pulse therapy with cyclophosphamide (CYC) followed by azathioprine and low-dose corticosteroids on SSc associated interstitial lung disease (SSc-ILD). METHODS: In a single-centre, prospective, observational, open-labelled study; nine patients (eight females, one male) with SSc-ILD were treated with intravenous pulse CYC (600mg/m(2) body surface area) at monthly interval for six cycles with oral prednisolone 10mg daily...
January 2016: Indian Journal of Chest Diseases & Allied Sciences
https://www.readbyqxmd.com/read/28194083/asbestos-induced-lung-disease-in-small-scale-clutch-manufacturing-workers
#11
Dipti Gothi, Tanushree Gahlot, Ram B Sah, Mayank Saxena, U C Ojha, Anand K Verma, Sonam Spalgais
BACKGROUND: The crocidolite variety of asbestos is banned. However, chrysotile, which is not prohibited, is still used in developing countries in making products such as clutch plate. Fourteen workers from a small-scale clutch plate-manufacturing factory were analyzed for asbestos-induced lung disease as one of their colleagues had expired due to asbestosis. AIMS: This study was conducted to evaluate the awareness of workers, the prevalence and type of asbestos-induced lung disease, and the sensitivity and specificity of diffusion test...
May 2016: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27922241/an-unusual-case-of-neuroblastoma-a-17-year-old-adolescent-presented-with-bilateral-diffuse-lung-metastasis-at-initial-diagnosis
#12
Çağlar Ödek, Tanıl Kendirli, Esra Pekpak, Ayhan Yaman, Başak Adaklı-Aksoy, Handan Dinçaslan, Nurdan Taçyıldız, Emel Ünal, Erdal İnce, Gülsan Yavuz
Neuroblastoma (NB) is the most frequently diagnosed neoplasm during infancy and its incidence declines within the first 3-5 years of life. It can be rarely diagnosed in adolescents and young adults. Adolescents have advanced stage of disease, higher frequency of uncommon metastatic sites such as lungs, and worse outcomes. Herein, we describe an unusual case of NB in a 17-year-old adolescent presented with lung metastasis at diagnosis. The patient was diagnosed with stage IV NB. Thorax high-resolution computed tomography (HRCT) scan revealed irregular septal thickening with ground glass opacity consistent with pulmonary parenchymal metastases...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27625983/eosinophil-alveolitis-in-two-patients-with-idiopathic-pulmonary-fibrosis
#13
Ninna Brix, Finn Rasmussen, Venerino Poletti, Elisabeth Bendstrup
Bronchoalveolar lavage fluid (BALF) in patients with idiopathic pulmonary fibrosis (IPF) is typically characterized by a neutrophil inflammatory pattern and to a lesser extent (<25%) a mild eosinophil alveolitis. We here present two patients with a definite usual interstitial pneumonia (UIP) pattern on high-resolution computed tomography of the thorax (HRCT) which demonstrated unusually high eosinophil counts in the BALF (40% and 51%). Based on HRCT, lack of response to steroids and the disease course they were both diagnosed as IPF after a multidisciplinary team discussion...
2016: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27481198/-idiopathic-pulmonary-fibrosis-prognostic-factors-analysis-of-the-czech-registry
#14
Martina Doubková, Michal Uher, Vladimír Bartoš, Martina Šterclová, Ladislav Lacina, Vladimíra Lošťáková, Ilona Binková, Martina Plačková, Monika Žurková, Radka Bittenglová, Jana Pšikalová, Lenka Šišková, Pavlína Lisá, František Petřík, Jaroslav Polák, Vladimír Řihák, Jana Skřičková, Martina Vašáková
UNLABELLED: Idiopathic pulmonary fibrosis (IPF) is a rare, progressive and usually fatal form of idiopathic interstitial pneumonia. IPF is characterized by failure of alveolar re-epithelization, persistence of fibroblasts, deposition of extracellular matrix, and distortion of lung architecture, which ultimately results in respiratory failure.We analysed 202 consecutive patients with IPF diagnosed at the Departments of Pulmonary Diseases and Tuberculosis in the Czech Republic, who they were included in the nationwide Czech IPF registry...
2016: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/27445532/pulmonary-langerhans-cell-histiocytosis-and-diabetes-insipidus-in-a-young-smoker
#15
K Earlam, C A Souza, R Glikstein, M M Gomes, S Pakhalé
Langerhans cell histiocytosis is characterized by the abnormal nodular proliferation of histiocytes in various organ systems. Pulmonary involvement seen in young adults is nearly always seen in the context of past or current cigarette smoking. Although it tends to be a single-system disease, extrapulmonary manifestations involving the skin, bone, and hypothalamic-pituitary-axis are possible. High resolution CT (HRCT) of the thorax findings includes centrilobular nodules and cysts that are bizarre in shape, variable in size, and thin-walled...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/27326955/recurrent-spontaneous-pneumothorax-during-pregnancy-managed-conservatively-a-case-report
#16
A H Mohamed Faisal, A Hazwani, C I Soo, Y L Andrea Ban
A 36-year-old lady presented with four episodes of right sided pneumothorax during pregnancy requiring multiple chest drain insertion. It was complicated with persistent air leak despite low pressure high volume suction applied to the chest drainage. She delivered safely through spontaneous vaginal delivery with chest drainage. Further imaging by high resolution computed tomography (HRCT) scan of thorax done revealed bilateral scattered pulmonary cysts and sub pleural bullae and was later followed up with respiratory unit...
April 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/27033049/esophageal-dilatation-and-interstitial-lung-disease-in-systemic-sclerosis-a-cross-sectional-study
#17
Carrie Richardson, Rishi Agrawal, Jungwha Lee, Orit Almagor, Ryan Nelson, John Varga, Michael J Cuttica, Jane D Amico Dematte, Rowland W Chang, Monique E Hinchcliff
OBJECTIVE: A patulous esophagus on high-resolution computed tomography (HRCT) of the thorax is frequently observed in patients with systemic sclerosis (SSc). Microaspiration has been purported to play a role in the development and progression of SSc interstitial lung disease (ILD), but studies examining the role of microaspiration in SSc ILD have yielded conflicting results. This study was conducted to determine the association between esophageal diameter and SSc ILD. METHODS: A cross-sectional study of Northwestern Scleroderma Registry patients with available HRCT exams was conducted...
August 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/26957274/effects-of-radiological-extent-on-neutrophil-lymphocyte-ratio-in-pulmonary-sarcoidosis
#18
N Ocal, D Dogan, R Ocal, E Tozkoparan, O Deniz, E Ucar, S Gumus, C Tasci, B Yildiz, G Taskin, A Taskin, S Badem, U Turhan
OBJECTIVE: Determining the severity of sarcoidosis is based on the clinical and radiological findings of the disease and the changes in pulmonary function test results. On the other hand; studies are ongoing for objective and easy markers in this respect. Neutrophil/lymphocyte ratio (NLR) is shown as a good prognostic marker for inflammation due to tissue damage in recent clinical trials. In this study, we aimed to identify the possible relationship between NLR and radiological extent of sarcoidosis...
2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/26933306/correlation-between-clinical-characteristics-spirometric-indices-and-high-resolution-computed-tomography-findings-in-patients-of-chronic-obstructive-pulmonary-disease
#19
Anubhuti Singh, Santosh Kumar, Ashwini Kumar Mishra, Manoj Kumar, Surya Kant, S K Verma, R A S Kushwaha, Rajiv Garg
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease affecting the airways, leading to significant morbidity and mortality throughout the world. There is a need to have a holistic evaluation of COPD patients, other than just measuring the level of obstruction as performed by spirometry. High resolution computed tomography (HRCT) scan of thorax partly fulfills this requirement. MATERIALS AND METHODS: Fifty patients of COPD (confirmed on spirometry as per the GOLD guidelines 2014 guidelines) were enrolled, out of which 35 patients got a HRCT done...
January 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/26628758/transbronchial-lung-biopsy-in-patients-with-diffuse-parenchymal-lung-disease-without-idiopathic-pulmonary-fibrosis-pattern-on-hrct-scan-experience-from-a-tertiary-care-center-of-north-india
#20
Girish Sindhwani, Nadia Shirazi, Rakhee Sodhi, Shailendra Raghuvanshi, Jagdish Rawat
BACKGROUND: Diffuse parenchymal lung diseases (DPLD) are a group of disorders characterized by chest radiological findings of bilateral diffuse shadowing. Lung biopsy is generally required to make an etiological diagnosis of DPLD's. Transbronchial lung biopsy (TBLB) is a minimally invasive method to achieve a lung sample which has been found to be a useful diagnostic tool in patients with DPLD. As per American Thoracic Society guidelines for management of idiopathic interstitial pneumonias, TBLB is not required in patients who have findings consistent with idiopathic pulmonary fibrosis (IPF) on HRCT scan thorax...
September 2015: Lung India: Official Organ of Indian Chest Society
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