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Screening colonoscopy interval

Ketra Rice, Krishna Sharma, Chunyu Li, Lynn Butterly, Joanne Gersten, Amy DeGroff
BACKGROUND: Colonoscopy is the most widely used colorectal cancer (CRC) screening test in the United States. Through the detection and removal of potentially precancerous polyps, it can prevent CRC. However, CRC screening remains low among adults who are recommended for screening. The New Hampshire Colorectal Cancer Screening Program implemented a patient navigation (PN) intervention to increase colonoscopy screening among low-income patients in health centers in New Hampshire. In the current study, the authors examined the cost-effectiveness of this intervention...
December 12, 2018: Cancer
Jasper L A Vleugels, Yark Hazewinkel, Marcel G W Dijkgraaf, Lianne Koens, Paul Fockens, Evelien Dekker
BACKGROUND: Optical diagnosis can replace histopathology of diminutive (1 - 5 mm) polyps if surveillance intervals based on optical diagnosis of polyps have ≥ 90 % agreement with intervals based on polyp histology and if the negative predictive value (NPV) for predicting neoplastic histology in the rectosigmoid is ≥ 90 %. This study aims to assess whether small (6 - 9 mm) polyps can be included in optical diagnosis strategies. METHOD: This is a post-hoc analysis of a prospective multicenter study in which 27 endoscopists, all performing endoscopies for the Dutch screening program, were trained in optical diagnosis...
December 13, 2018: Endoscopy
Isabel Idigoras Rubio, Eunate Arana-Arri, Isabel Portillo Villares, Isabel Bilbao Iturribarrria, Lorea Martínez-Indart, Natale Imaz-Ayo, Marta de la Cruz, Visitación de Castro, Arantza López de Munain, Idoia Torrejón Perez, Iñaki Gutiérrez-Ibarluzea
BACKGROUND: The steady increase in colorectal cancer (CRC) could be reversed through timely secondary prevention (screening) as a main strategy. The aims of this study were to determine the main features of CRC, survival rate and related factors for different types of identified CRCs in a population-based screening programme using the faecal immunochemical test (FIT). MATERIALS AND METHODS: The CRCs in the susceptible population to be screened between 2009 and 2014 were identified and classified into four groups: (a) nonscreening-detected CRC (diagnosed before first screening invitation and nonparticipants), (b) screening-detected CRC, (c) interval cancer (IC) FIT (diagnosed between screening rounds after a negative FIT) and (d) IC colonoscopy (diagnosed before the colonoscopy surveillance, which is recommended after the screening colonoscopy)...
December 12, 2018: European Journal of Gastroenterology & Hepatology
Mette Kielsholm Thomsen, Morten Rasmussen, Sisse Helle Njor, Ellen Margrethe Mikkelsen
Background: Predictors of participation in colorectal cancer screening with a stool sample screening modality have been widely studied, but adherence to subsequent diagnostic colonoscopy after a positive screening test has received less attention. We aimed to determine predictors of adherence to diagnostic colonoscopy in the Danish Colorectal Cancer Screening Program. Methods: We conducted a cross-sectional study using data from National Health Service registries...
2018: Clinical Epidemiology
Michael Selgrad, Jan Bornschein, Arne Kandulski, Jochen Weigt, Albert Roessner, Thomas Wex, Peter Malfertheiner
BACKGROUND: Our aim was to evaluate the feasibility of a serological assessment of gastric cancer risk in patients undergoing colonoscopy in countries with low-to-moderate incidence rates. METHODS: Serum samples were prospectively collected from 453 patients (>50 years old) undergoing colonoscopies. Of these, 279 (61.6%) also underwent gastroscopy to correlate the results for serum pepsinogen I and II (sPG-I and sPG-II), sPG-I/II ratio, and anti- H. pylori antibodies with gastric histopathology findings (graded according to the updated Sydney classification and the Operative Link of Gastritis Assessment (OLGA) and the Operative Link for Gastric Intestinal Metaplasia assessment (OLGIM) systems)...
December 3, 2018: International Journal of Molecular Sciences
Elisa Stasi, Andrea Michielan, Gaetano Cristian Morreale, Alessandro Tozzi, Ludovica Venezia, Francesco Bortoluzzi, Omero Triossi, Marco Soncini, Gioacchino Leandro, Giuseppe Milazzo, Andrea Anderloni
Modern medicine provides almost infinite diagnostic and therapeutic possibilities if compared to the past. As a result, patients undergo a multiplication of tests and therapies, which in turn may trigger further tests, often based on physicians' attitudes or beliefs, which are not always evidence-based. The Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) adhered to the Choosing Wisely Campaign to promote an informed, evidence-based approach to gastroenterological problems. The aim of this article is to report the five recommendations of the AIGO Choosing Wisely Campaign, and the process used to develop them...
November 29, 2018: Internal and Emergency Medicine
Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Yoon Suk Jung
BACKGROUND: There are no established guidelines on screening strategies for persons with a family history of colorectal cancer (CRC) in Korea. We aimed to evaluate the age-specific risk of colorectal neoplasia according to family history of CRC. METHODS: Participants who underwent screening colonoscopy were included. Age-specific prevalence of non-advanced adenoma (NAA) and advanced colorectal neoplasia (ACRN) was calculated according to family history of CRC. RESULTS: Among 35,997 participants, 1,339 (3...
November 21, 2018: Journal of Gastroenterology and Hepatology
Sama Rezasoltani, Maryam Sharafkhah, Hamid Asadzadeh Aghdaei, Ehsan Nazemalhosseini Mojarad, Hossein Dabiri, Abbas Akhavan Sepahi, Mohammad Hossein Modarressi, Mohammad Mehdi Feizabadi, Mohammad Reza Zali
BACKGROUND: Colorectal cancer (CRC) is the third leading cause of cancer, and presents a considerable disease burden, worldwide. Recently, the gut microbiota has been proposed as a potential risk factor for CRC, and even adenomatous polyps (AP). Here, the aim of this study was to investigate the role of selected gut bacteria as fecal bacterial biomarkers, in early detection of CRC and AP. MATERIAL AND METHODS: Fecal samples (n = 93) were collected from Taleghani Hospital, Tehran, Iran, between 2015 and 2017, from normal controls (NC), AP cases and CRC stage I patients, who were undergoing screening for colonoscopy...
November 12, 2018: Journal of Microbiological Methods
Anne Starker, Nina Buttmann-Schweiger, Laura Krause, Benjamin Barnes, Klaus Kraywinkel, Christine Holmberg
In Germany, approximately 227,000 women and 249,000 men developed cancer in 2014, and nearly 223,000 patients died from the disease that year. Many cancers are curable or have a very good prognosis when they are diagnosed at an early stage. This is where the concept of early detection examinations comes into play.This article describes the current conditions of and participation in examinations for the early detection of cervical, breast, skin, prostate, and colon cancer as provided by Germany's statutory health services...
December 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Hyo-Joon Yang, Chang Woo Cho, Sang Soo Kim, Kwang-Sung Ahn, Soo-Kyung Park, Dong Il Park
BACKGROUND AND AIMS: We aimed to develop deep learning models for the prediction of the risk of advanced colorectal neoplasia (ACRN) in asymptomatic adults based on which colorectal cancer screening could be customized. METHODS: We collected data on 26 clinical and laboratory parameters including age, sex, smoking status, body mass index, complete blood count, blood chemistry, and tumor marker from 70,336 first-time screening colonoscopy recipients. For reference, we used a logistic regression (LR) model with nine variables...
November 4, 2018: Gastrointestinal Endoscopy
Audrey H Calderwood, Joseph C Anderson, Christina M Robinson, Lynn F Butterly
OBJECTIVES: Although the 2008 US Preventive Services Task Force guidelines recommend against routine colorectal cancer (CRC) screening for adults aged 76-85, it is unclear what endoscopists recommend in practice. Our goal was to examine current practice around cessation of CRC screening in older adults. METHODS: We included normal screening colonoscopy exams in adults ≥ 50 years old within the New Hampshire Colonoscopy Registry between 2009 and 2014. The primary outcome was endoscopists' recommendation against further screening...
November 2, 2018: American Journal of Gastroenterology
Chi-Liang Cheng, Nai-Jen Liu, Jui-Hsiang Tang, Yen-Lin Kuo, Cheng-Hui Lin, Jau-Min Lien, Yi-Ning Tsui, Bai-Ping Lee, Hsiang-Ling Hung
GOAL: The goal of this study was to estimate the risk of renal injury after the use of 3-L polyethylene glycol (PEG) before outpatient colonoscopy. BACKGROUND: Population-based studies showed that the use of PEG was associated with renal injury, but this association has not been confirmed by prospective study. STUDY: Patients ≥40 years of age with an estimated glomerular filtration rate ≥30 mL/min were screened for enrollment. Laboratory data were collected before, during, and after the colonoscopies...
October 24, 2018: Journal of Clinical Gastroenterology
Takuji Kawamura, Shiho Nakamura, Daiki Sone, Hiroaki Sakai, Kana Amamiya, Naonori Inoue, Naokuni Sakiyama, Atsushi Shirakawa, Yusuke Okada, Kasumi Sanada, Kojiro Nakase, Koichiro Mandai, Azumi Suzuki, Atsuhiro Morita, Kiyohito Tanaka, Koji Uno, Kenjiro Yasuda
BACKGROUND & AIMS: Because the risk of colorectal cancer (CRC) has not been well examined in fecal immunochemistry test (FIT)-positive patients who previously underwent colonoscopy, this study aimed to investigate this topic. METHODS: This was a single-center, observational study of prospectively collected data in Japan. FIT-positive, average-risk patients who underwent colonoscopy were divided into groups as follows: (1) those who never underwent colonoscopy in the past (no colonoscopy group), (2) those with a history of colonoscopy between 6 months and 5 years (0...
October 24, 2018: Journal of Gastroenterology and Hepatology
Sarah D Peacock, Thomas E Massey, Stephen J Vanner, Will D King
Telomere length has been associated with risk of several cancers. However, studies of the relationship between telomere length and colorectal cancer risk have been inconsistent. This study examined the relationship between telomere length in normal colon tissue and the prevalence of colorectal adenoma, a precursor to colorectal cancer. This nested case-control study consisted of 85 patients aged 40 to 65 undergoing a screening colonoscopy: 40 cases with adenoma(s) detected at colonoscopy and 45 controls with normal colonoscopy...
2018: PloS One
T H Lam, K H Wong, K Kl Chan, M Cm Chan, D Vk Chao, A Ny Cheung, C Ym Fan, J Ho, E P Hui, K O Lam, C K Law, W L Law, H Hf Loong, R Kc Ngan, T Hf Tsang, M Cs Wong, R Mw Yeung, A Ch Ying, R Ching
Colorectal cancer is the commonest cancer in Hong Kong. The Cancer Expert Working Group on Cancer Prevention and Screening was established in 2002 under the Cancer Coordinating Committee to review local and international scientific evidence, assess and formulate local recommendations on cancer prevention and screening. At present, the Cancer Expert Working Group recommends that average-risk individuals aged 50 to 75 years and without significant family history consult their doctors to consider screening by: (1) annual or biennial faecal occult blood test, (2) sigmoidoscopy every 5 years, or (3) colonoscopy every 10 years...
October 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
Aasma Shaukat, Nabiha Shamsi, Jeremiah Menk, Timothy R Church, Jeffery Rank, Joshua Colton
BACKGROUND & AIMS: Accurate sizing of polyps and improving adenoma detection rates (ADR) are important goals for high-quality colonoscopy. Surveillance intervals are based on accurate sizing of polyps. There are no clinical tools or interventions that have demonstrated improvement in both these metrics. We investigated the efficacy of a simple, low-cost intervention, based on use of polyp sizing posters to improve measurements of polyps and increase ADRs during colonoscopy at a large gastroenterology community practice...
October 9, 2018: Clinical Gastroenterology and Hepatology
Elizabeth Hatfield, Jane S Green, Michael O Woods, Geoff Warden, Patrick S Parfrey
BACKGROUND: Hereditary Non-Polyposis Colorectal cancer is caused by Lynch Syndrome (LS; an autosomal dominant condition) or by Familial Colorectal Cancer Type-X (FCCTX; a condition of high family risk that fulfills Amsterdam criteria). The lifetime risk of developing colorectal cancer (CRC) in FCCTX family members is high and CRC occurs later than in LS. METHODS: To determine the impact of primary prevention colonoscopic screening in asymptomatic first-degree relatives of incident CRC cases in 20 families with FCCTX, we compared cancer incidence and survival in 79 males and 83 females, assumed to be at 50% risk of inheriting a genetic CRC susceptibility factor, who entered screening to an unscreened control group from the families, matched for age at entry into screening and for sex...
October 9, 2018: Molecular Genetics & Genomic Medicine
Manuel Zorzi, Cesare Hassan, Giulia Capodaglio, Elena Narne, Anna Turrin, Maddalena Baracco, Antonella Dal Cin, Annarita Fiore, Giancarla Martin, Alessandro Repici, Douglas Rex, Massimo Rugge
Background: Short-term studies have reported that the fecal immunochemical test (FIT) is less accurate in detecting proximal than distal colorectal neoplasia. Objective: To assess the long-term detection rates for advanced adenoma and colorectal cancer (CRC), according to anatomical location. Design: Retrospective study. Setting: Population-based, organized screening program in the Veneto region of Italy. Participants: Persons aged 50 to 69 years who completed 6 rounds of FIT screening...
October 2, 2018: Annals of Internal Medicine
Haim Shirin, Beni Shpak, Julia Epshtein, John Gásdal Karstensen, Arthur Hoffman, Rogier de Ridder, Pier Alberto Testoni, Sauid Ishaq, D Nageshwar Reddy, Seth A Gross, Helmut Neumann, Martin Goetz, Dov Abramowich, Menachem Moshkowitz, Meir Mizrahi, Peter Vilmann, Johannes Wilhelm Rey, Silvia Sanduleanu-Dascalescu, Edi Viale, Hrushikesh Chaudhari, Mark B Pochapin, Michael Yair, Mati Shnell, Shaul Yaari, Jakob Westergren Hendel, Daniel Teubner, Roel M M Bogie, Chiara Notaristefano, Roman Simantov, Nathan Gluck, Eran Israeli, Trine Stigaard, Shay Matalon, Alexander Vilkin, Ariel Benson, Stine Sloth, Amit Maliar, Amir Waizbard, Harold Jacob, Peter Thielsen, Eyal Shachar, Shmuel Rochberger, Tiberiu Hershcovici, Julie Isabelle Plougmann, Michal Braverman, Eduard Tsvang, Armita Armina Abedi, Yuri Brachman, Peter D Siersema, Ralf Kiesslich
BACKGROUND AND AIMS: Colorectal cancer (CRC) is largely preventable with routine screening and surveillance colonoscopy; however, interval cancers arising from precancerous lesions missed by standard colonoscopy still occur. An increased adenoma detection rate (ADR) has been found to be inversely associated with interval cancers. The G-EYE device includes a reusable balloon integrated at the distal tip of a standard colonoscope, which flattens haustral folds, centralizes the colonoscope's optics, and reduces bowel slippage...
September 28, 2018: Gastrointestinal Endoscopy
Helmut Neumann, Helmut Neumann Sen, Michael Vieth, Raf Bisschops, Florian Thieringer, Khan F Rahman, Thomas Gamstätter, Gian Eugenio Tontini, Peter R Galle
Objectives: A negative predictive value of more than 90% is proposed by the American Society of Gastrointestinal Endoscopy Preservation and Incorporation of Valuable Endoscopic Innovations (PIVI) statement for a new technology in order to leave distal diminutive colorectal polyps in place without resection. To our knowledge, no prior prospective study has yet evaluated the feasibility of the most recently introduced blue light imaging (BLI) system for real-time endoscopic prediction of polyp histology for the specific endpoint of leaving hyperplastic polyps in place...
August 2018: United European Gastroenterology Journal
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