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Sinus infections and staph

Edward D McCoul
Background: Unilateral, mucopurulent drainage from an isolated paranasal sinus may be encountered in patients with a history of surgery for the treatment of chronic rhinosinusitis (CRS). Static mucus is visualized on nasal endoscopy within the sinus lumen but without significant disease in the adjacent sinuses. The reasons for this phenomenon are unknown although an iatrogenic cause is proposed. Methods: A case series was prospectively compiled from consecutive patients presenting for evaluation of CRS at a tertiary rhinology practice during a 16-month period...
2018: Ochsner Journal
Yi Dong, Bing Zhou, Zhenxiao Huang, Qian Huang, Shunjiu Cui, Yunchuan Li, Erzhong Fan, Ying Li, Xinyan Wang
BACKGROUND: The traditional method of evaluating bone remodeling in chronic rhinosinusitis is to measure bone thickness. The objective of this study was to determine the feasibility of measuring the computed tomography (CT) value in Hounsfield units (HU) as an method and explore whether it is superior to measuring bone thickness. METHODS: The study was a prospective animal trial. Twenty normal rabbits were included in the control group, and 60 rabbit models were inoculated with Staphylococcus aureus to induce rhinosinusitis...
September 20, 2018: International Forum of Allergy & Rhinology
Zhisen Gao, Yinqiao Du, Shang Piao, Jingyang Sun, Xiang Li, Yonggang Zhou
BACKGROUND: Staphylococcus species are major pathogens of peri-prosthetic joint infection (PJI). Coagulase-positive staphylococci and coagulase-negative staphylococci have different intrinsic virulences. However, few studies have specifically compared the clinical manifestations and two-stage revision outcomes of PJI caused by these two species. METHODS: We retrospectively collected 260 arthroplasty patients who underwent a two-stage revision because of PJI from January 2003 to June 2015 in our institute because of PJI...
September 1, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
Ryan G Short, Tina D Tailor
History A 31-year-old woman with a history of bilateral orthotopic lung transplantation performed 10 months earlier for cystic fibrosis presented for a routine follow-up appointment, with her chief symptom being a cough. The cough started approximately 1 month prior to this appointment and was minimally productive of clear to yellow phlegm. In addition to her cough, she reported increased sinus congestion and a sensation of "something in her upper chest." She denied shortness of breath, wheezing, hemoptysis, or cigarette smoking...
August 2018: Radiology
Xianmin Wu, Yue Zhang, Xiaoyun Chen, Jun Chen, Minghui Jia
BACKGROUND: Staphylococcus aureus is the most commonly isolated bacterium from patients with surgically recalcitrant chronic rhinosinusitis (CRS). Understanding the immune responses to S aureus biofilms will provide insights into how the host response may be manipulated by therapeutic agents to improve the chances of successfully preventing and treating these infections. In this study, we investigated the inflammatory immune response in a rabbit model of S aureus biofilm-related sinusitis by analyzing the levels of some major inflammatory cytokines...
July 6, 2018: International Forum of Allergy & Rhinology
Ricardo Cienfuegos, Gerardo Fernández, Aída Cruz, Eduardo Sierra
Introducción: Los defectos craneales secundarios a traumatismos son frecuentes. Por lo común se reparan de forma secundaria por sintomatología como el síndrome del paciente trepanado, por protección cerebral y por el aspecto cosmético. Históricamente se han utilizado diversos materiales para la reconstrucción. Casos clínicos: Se presentan cinco casos de pacientes reconstruidos con implantes personalizados de polieteretercetona (PEEK) o polimetilmetacrilato poroso (PMMA)...
2018: Cirugia y Cirujanos
Y Liu, L Fan, Y Q Tang, Z Y Zhang
Objective: To investigate the prevalence and drug sensitivity of nasal Staphylococcus aureus infection in patients with chronic sinusitis and healthy controls. Method: Bacterial culture and drug sensitivity test were performed in 71 patients with CRS (experimental group) and 103 healthy controls (control group). The infection rate of Staphylococcus aureus and the sensitivity of the drug were analyzed based on these results. Result: Twenty-nine Staphylococcus aureus strains were isolated from 71 cases of patients in the experimental group, and the positive rate was 40...
June 5, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Nicola E Natsis, Philip R Cohen
Coagulase-negative staphylococcus organisms may be normal flora of human skin, however these bacteria can also be pathogens in skin and soft tissue infections. A summary of skin and soft tissue infections caused by coagulase-negative staphylococcus species is provided in this review. We conducted a search of the PubMed database using the following terms: abscess, auricularis, biofilm, capitis, cellulitis, coagulase, contaminant, cyst, draining, epidermidis, felon, folliculitis, furuncle, haemolyticus, hominis, indolent, infection, lugdunensis, mecA, microbiome, negative, osteomyelitis, paronychia, saprophyticus, skin, simulans, sinus, soft, staphylococcus, systemic, tissue, virulence, virulent, and vulvar...
June 7, 2018: American Journal of Clinical Dermatology
Guang Song, Jing Zhang, Xintong Zhang, Huan Yang, Wanying Huang, Ming Du, Ke Zhou, Weidong Ren
BACKGROUND: Infective endocarditis (IE) is a rare disease with high mortality. Right-sided IE accounts for 5-10% of cases of IE. The tricuspid valve is most commonly affected, oppositely in coronary sinus (CS). The diagnoses, treatments and outcomes of CS vegetation has not been summarized yet. CASE PRESENTATION: We present a 71-year-old man complained of cough and fever. Transthoracic echocardiography revealed the aneurysmal dilated CS with the band medium-echo mobile structure...
June 4, 2018: BMC Cardiovascular Disorders
Visakha Suresh, Rachel Anolik, David Powers
PURPOSE: Polyether-ether-ketone (PEEK) implants have become increasingly popular for use in reconstructive procedures. It is imperative to understand the consequences of using this biomaterial in anatomic sites that can pose a risk of infection. Specifically, the use of PEEK in paranasal sinus cavity reconstruction is not well documented. This study examined postoperative complications, namely surgical site infection and implant loss, in patients who underwent paranasal sinus cavity reconstruction using PEEK implants...
May 10, 2018: Journal of Oral and Maxillofacial Surgery
Longlong Shao, Ping Zhen, Yonghai Ma, Dong Gong, Yunlong Wang
Objective: To investigate the appropriate concentration of methicillin-resistant Staphylococcus aureus (MRSA) in establishing chronic femoral osteomyelitis model in rabbits. Methods: Forty-eight adult New Zealand white rabbits were randomly divided into 6 groups with 8 rabbits in each group. Animals in groups B, C, D, E, and F were injected 1×10 9 , 1×10 8 , 1×10 7 , 1×10 6 , 1×10 5 CFU/mL MRSA on the location of 2 cm of the femoral supracondyle, respectively, and group A was injected with aseptic saline as a control...
April 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
L Liang, L Q Chen, L S Chen, B Zhang, S L Huang, X X Gong, S Y Zhang, X N Luo, J H Xie
Objective: To identify the pathogenic bacteria of CPSF and their resistance to antibiotics,and guide the rational use of antibiotics therapy. Method: One hundred and thirty cases of deep neck infection whose imaging finding depicted patients with suspected as CPSF were enrolled in the study from January 2010 to June 2017.Specimens were collected from abscesses or other inflammatory lesions from all patients through a small incision or the external orifice on the skin of the neck. Result: A total of 108 strains of pathogens have been isolated from 88 patients (positive rate: 67...
April 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Y Liu, Q Luo, L Fam, Y Q Tang, Q Chen, Z Y Zhang
Objective: To investigate the differences of virulence genes of Staphylococcus aureus in patients with chronic sinusitis with nasal polyps (CRSwNP) and chronic sinusitis without nasal polyps (CRSsNP), and to explore the relationship between different virulence factors and the incidence of sinusitis and nasal polyps. Method: The PCR method was used to detect 17 kinds of virulence genes of Staphylococcus aureus isolated from nasal secretions of 41 strains. Result: ①The detection rate of SEB in the experimental group was significantly higher than that in the control group, the detection rate of SEB in the CRSwNP group was higher than that in the CRSsNP group, and the other 5 kinds of enterotoxin genes were not statistically significant between the experimental group and the control group;②Staphylococcus aureus adhesin in the experimental group and the control group were detected, and the detection rate was relative higher in both control and experimental goups...
September 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Peter G Speck, Peter-John Wormald
No abstract text is available yet for this article.
May 2018: Future Microbiology
Yujia Lin, Glory Leung, Dante Louie, Ania Bogoslowski, James Ross, Paul Kubes, Pierre-Yves von der Weid, Shan Liao
Lymphatic vessels remove and transport excess interstitial fluid to lymph nodes (LNs) for fluid balance and immune protection. LNs are typically surrounded by perinodal adipose tissue (PAT). However, PAT is a blood vessel-rich but lymphatic-rare tissue; therefore, how excess fluid in PAT is removed remains unclear. Using C57BL/6 mice, fluorescent dye tracing and transmission electron microscopy results suggest that fluid in PAT can travel to the LN via collagen I+ channels (PAT-LN conduits), merge into a collagen-rich space between the PAT and LN capsule (PAT-LN sinus), and may enter the LN via the LN capsule-associated conduits...
July 1, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
Wondemagegn Mulu, Endalew Yizengaw, Megbaru Alemu, Daniel Mekonnen, Derese Hailu, Kassaw Ketemaw, Bayeh Abera, Mulugeta Kibret
BACKGROUND: Asymptomatic pharyngeal colonization by potential bacteria is the primary reservoir for bacterial species within a population and is considered a prerequisite for development of major childhood diseases such as sinusitis, otitis media, pneumonia, bacteremia, and meningitis. However, there is dearth of data on the colonization and drug resistance pattern of the main bacterial pathogens in the pharynx of HIV infected children in Ethiopia. Therefore, this study determined the pharyngeal colonization and drug resistance profile of bacterial pathogens in HIV infected children attending ART clinic of Felegehiwot Referral Hospital (FHRH), Amhara Region, Ethiopia...
2018: PloS One
Zhi-Sen Gao, Yong-Gang Zhou, Yin-Qiao Du, Shang Piao, Jing-Yang Sun, Ya-Wen Peng, Wen-Ming Wu
OBJECTIVE: To investigate the risk factors for the failure in treating periprosthetic infection of coagulase-negative staphylococci by two-stage revision. METHODS: From January 2005 to June 2015, 57 patients with periprosthetic hip and knee joint infection of coagulase-negative staphylococcus by two-stage revision were retrospectively reviewed with an average age of (61.3±11.9) years old. According to the drug resistance of methicillin, the patients were divided into methicillin sensitive group(MSCoN) and methicillin resistance(MRCoN) group, 25 cases in MSCoN group(9 knees and 16 hips) included 12 males and 13 females, 32 cases in MRCoN group(11 knees and 21 hips) included 14 males and 18 females...
February 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Whittney A Warren, Domingo Franco-Palacios, Christopher S King, Oksana A Shlobin, Steven D Nathan, Shalika B Katugaha, Haresh Mani, A Whitney Brown
A 24-year-old woman with ΔF508/Y1092X cystic fibrosis (CF) complicated by severe obstructive lung disease (FEV1 of 30% predicted) was admitted for IV antibiotics for planned sinus surgery resulting from severe chronic sinusitis causing frequent exacerbations and declining lung function. She had persistent airway infection with multidrug-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, and growth of a fungus presumed to be an airway colonizer, identified as Stephanoascus ciferrii 1 year before presentation...
March 2018: Chest
Nora Renz, Sabrina Cabric, Christian Morgenstern, Michael A Schuetz, Andrej Trampuz
INTRODUCTION: Bone healing disturbance following fracture fixation represents a continuing challenge. We evaluated a novel fully automated polymerase chain reaction (PCR) assay using sonication fluid from retrieved orthopedic hardware to diagnose infection. PATIENTS AND METHODS: In this prospective diagnostic cohort study, explanted orthopedic hardware materials from consecutive patients were investigated by sonication and the resulting sonication fluid was analyzed by culture (standard procedure) and multiplex PCR (investigational procedure)...
April 2018: Injury
Supawon Srettabunjong
Septic cavernous sinus thrombosis (SCST) is an uncommon consequence of head and face infection, but a rare complication after craniofacial fracture. In this case, SCST developed in a 13-year-old girl following a minor fall during volleyball, with impact and resulting abrasive contusion of the left forehead. She developed watery rhinorrhea, progressive headache, fever, nausea, vomiting, and left proptosis with blurred vision, and was admitted to hospital 3 days after injury. Drowsiness, high-grade fever, severe headache, left ocular pain with marked periorbital swelling, and paralysis of extraocular eye movements developed...
February 21, 2018: Journal of Forensic Sciences
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