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Anna Lechner, Nils Lahmann, Andrea Lichterfeld-Kottner, Ursula Müller-Werdan, Ulrike Blume-Peytavi, Jan Kottner
Aims: To describe the prevalence of dry skin in nursing homes and hospitals and to describe relationships between topical skincare interventions and dry skin. Design: Two multicentre descriptive cross-sectional prevalence studies. Methods: The studies were performed in German nursing homes and hospitals in 2015 and 2016. Data were collected by trained nurses based on a standardized data collection form. The severity of dry skin was measured using the Overall Dry Skin Score...
January 2019: Nursing Open
Ana Elisa Ribeiro, Naice Eleidane Santana Monteiro, Anna Valéria Gueldini de Moraes, Lucia Helena Costa-Paiva, Adriana Orcesi Pedro
OBJECTIVE: To evaluate the effect of isoflavone administration, either in conjunction with probiotic use or not, on the symptoms of genitourinary syndrome of menopause, and compare the effects with those of hormone therapy. METHODS: A randomized clinical trial was conducted on 60 postmenopausal women aged 40 to 60 years, randomly assigned to receive oral isoflavone (150 mg dry extract of glycine max) alone or isoflavone plus probiotic (Lactobacillus acidophilus, Lactobacillus casei, Lactococcus lactis, Bifidobacterium bifidum, and Bifidobacterium lactis) or hormone therapy (1 mg estradiol and 0...
December 10, 2018: Menopause: the Journal of the North American Menopause Society
Samaneh Ebrahimi, Mandana Gholami
OBJECTIVE: There is limited research on voice problems of athletes, especially Kabaddi athletes who use their voice during Kabaddi exercises and may damage their vocal folds and impair their voice quality. The present study aimed to compare maximum oxygen uptake (VO2 max) and rating perceived exertion (RPE) in Woman's Kabaddi athletes without breathy voice (BV) to severe BV. MATERIALS AND METHODS: Seventy woman's Kabaddi athletes (mean age of 20.5 ± 2.7 years, height of 163 ± 3...
December 7, 2018: Journal of Voice: Official Journal of the Voice Foundation
M H J Hollander, M Contini, J W Pott, A Vissink, R H Schepers, J Jansma
OBJECTIVE: Various functional outcomes after upper blepharoplasty are reported in the literature. We systematically reviewed the literature to assess the objective and subjective functional effects of upper blepharoplasty. METHODS: After a systematic search of four search engines (Pubmed, Embase, Cinahl and Cochraine), any study on objective and subjective (patient reported) functional outcome after upper blepharoplasty was subjected to a quality assessment for possible inclusion in the review...
November 22, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Lindong Weng, Shannon L Stott, Mehmet Toner
Successful stabilization and preservation of biological materials often utilize low temperatures and dehydration to arrest molecular motion. Cryoprotectants are routinely employed to help the biological entities survive the physicochemical and mechanical stresses induced by cold or dryness. Molecular interactions between biomolecules, cryoprotectants, and water fundamentally determine the outcomes of preservation. The optimization of assays using the empirical approach is often limited in structural and temporal resolution, whereas classical molecular dynamics simulations can provide a cost-effective glimpse into the atomic-level structure and interaction of individual molecules that dictate macroscopic behavior...
December 10, 2018: Annual Review of Biomedical Engineering
Emine Esra Karaca, Özlem Evren Kemer, Dilay Özek
PURPOSE: To assess the effect of intense regulated pulse light (E-Eye; E-Swin, France) on the treatment of meibomian gland dysfunction. SETTING: Health Sciences University, Ankara Numune Training and Research Hospital, Department of Ophthalmology. METHODS: A total of 26 patients underwent intense pulsed light treatment (E-Eye; E-Swin), with homogeneously sequenced five light pulses delivered to one eye at 1, 15, and 45 days following baseline evaluation...
December 4, 2018: European Journal of Ophthalmology
Violante Di Donato, Michele Carlo Schiavi, Valentina Iacobelli, Ottavia D'oria, Evangelos Kontopantelis, Tommaso Simoncini, Ludovico Muzii, Pierluigi Benedetti Panici
OBJECTIVE: To evaluate the efficacy of ospemifene in treating dyspareunia associated with postmenopausal vulvo-vaginal atrophy (VVA). METHODS: A structured search was carried out in PubMed-Medlin, Embase, Cochrane Controlled Trials Register databases through to 31 July 2018. The search included the following terms: "Ospemifene", "vulvovaginal atrophy", "dyspareunia", "SERM" and "randomized controlled trial" (RCTs)...
November 24, 2018: Maturitas
Devin R Halleran, Benjamin Thompson, Molly Fuchs, Alejandra Vilanova-Sanchez, Rebecca M Rentea, D Gregory Bates, Kate McCracken, Geri Hewitt, Christina Ching, Daniel DaJusta, Marc A Levitt, Richard J Wood
AIM OF THE STUDY: The goals of urinary reconstruction in urogenital sinus and cloacal repair include: (1) positioning of the bladder neck above the urogenital diaphragm to maximize future urinary continence, and (2) creating a visible urethra that can be catheterized if needed. A recent algorithm in cloacal reconstruction proposed a urethral length of 1.5 cm as the key determinant in deciding whether to perform a total urogenital mobilization or a urogenital separation, the hypothesis being that a 1...
November 7, 2018: Journal of Pediatric Surgery
Maryam Kiumarsi, Mahdiyar Shahbazi, Samira Yeganehzad, Dorota Majchrzak, Oliver Lieleg, Benjamin Winkeljann
Gluten-free bread was fortified with modified dietary fibers (wheat bran, resistant starch and inulin) and their effects on water mobility, friction coefficient, thermal behavior, crystalline pattern and textural properties were evaluated. Moreover, time-intensity evaluation was used to study temporal dynamics of sensory attributes of fortified-breads. Dietary fibers increased gelatinization temperature while decreasing gelatinization enthalpy, more notably when inulin was used. X-ray diffraction patterns of bread showed the appearance of new peaks after addition of resistant starch and wheat bran, coinciding with an increase in crumb hardness...
March 30, 2019: Food Chemistry
Rehab Nabil Shamma, Sinar Sayed, Nirmeen Ahmed Sabry, Solwan Ibrahim El-Samanoudy
Acne vulgaris is the most common dermatological disorder affecting millions of individuals. Acne therapeutic solutions include topical treatment with retinoic acid (RA) which showed a god efficacy in treatment of mild and moderate cases. However, the high prevalence of adverse events, such as skin dryness, shedding and skin irritation affects the patient convenience and obstruct the acne treatment. Thus, the objective of this paper was to produce Span 60 based elastic vesicles enriched with penetration enhancers, and study their influence on the delivery of RA and its skin irritation...
December 2, 2018: Journal of Liposome Research
Zoe Diana Draelos
Facial skin aging is accelerated in postmenopausal females due to decreased collagen, reduced hydration, and loss of skin elasticity constituting the characteristics of estrogen deficient skin (EDS). The presence of estrogen receptors on dermal fibroblasts and epidermal keratinocytes confirms the role of estrogen in skin health. This research examined the efficacy and tolerability of topical methyl estradiolpropanoate (MEP) as an anti-aging cosmeceutical with estrogen like cutaneous effects in postmenopausal women who had never taken hormone replacement therapy (HRT)...
November 1, 2018: Journal of Drugs in Dermatology: JDD
Yanli Yan, Long Zhang, Li Tan, Xiaowei Ma, Yong Zhang, Shuai Shao, Jiaxin Liu, Chaofan Xue, Zongfang Li, Xiaozhi Zhang, Emmanuel Kwateng Drokow, Xiaoting Shi, Juan Ren
The management of ductal carcinoma in situ (DCIS) with endocrine therapy remains controversial. A meta-analysis was conducted to evaluate the role of endocrine therapy for DCIS with breast conserving surgery (BCS) and radiotherapy (RT). A total of 7 articles with randomized controlled trials were included. Five articles compared the effects of BCS and RT followed by tamoxifen (TAM) or not (BCS + RT + TAM vs BCS + RT) and 2 compared the effects of TAM and anastrozole (ANA). TAM obviously reduced the rates of recurrence of ipsilateral breast cancer (IBCR), recurrence of contralateral breast cancer (CBCR), recurrence of ipsilateral invasive breast cancer (IBCR-INV) and recurrence of contralateral DCIS (CBCR-DCIS), and increased the rate of event-free survival (EFS)...
November 29, 2018: Pathology Oncology Research: POR
Petra Larmo, Riikka Järvinen, Jarmo Laihia, Eliisa Löyttyniemi, Laura Maavirta, Baoru Yang, Heikki Kallio, Minna Sandberg-Lall
PURPOSE: To investigate the effects of a sea buckthorn oil and sodium hyaluronate-containing eyelid spray emulsion (SB spray) on dry eye. METHODS: A randomized controlled study was carried out. Adults (25-70 years) with Ocular Surface Disease Index (OSDI) ≥20 and moderate or severe dryness, burning or grittiness of the eyes were included. In study part one (n = 2), SB spray was used on both closed eyelids four times in one day. In part two (n = 10), SB spray was used on one randomized eyelid, and a commercial reference spray on the other for nine days...
November 26, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Hui Liu, Yongxuan Wei, Zhi Deng, Hong Yang, Longjun Dai, Dejun Li
Tapping panel dryness (TPD) causes a significant reduction in the latex yield of rubber tree (Hevea brasiliensis Muell. Arg.). It is reported that TPD is a typical programmed cell death (PCD) process. Although PCD plays a vital role in TPD occurrence, there is a lack of detailed and systematic study. Metacaspases are key regulators of diverse PCD in plants. Based on our previous result that HbMC1 was associated with TPD, we further elucidate the roles of HbMC1 on rubber tree TPD in this study. HbMC1 was up-regulated by TPD-inducing factors including wounding, ethephon and H2O2...
November 29, 2018: Tree Physiology
Punita Lal, Vipul Nautiyal, Mranalini Verma, Rajan Yadav, K J Maria Das, Shaleen Kumar
Background: Parotid-sparing intensity-modulated radiotherapy (IMRT) effectively reduces xerostomia in head-and-neck cancer (HNC). Changes in the salivary output at 1 year were studied and correlation with quality of life (QOL) changes in patients of locally advanced HNC (LAHNC) was drawn. Materials and Methods: Between October 2009 and October 2011, 20 patients of LAHNC were treated with IMRT using simultaneous integrated boost technique. High-risk clinical target volume (CTV) was given a dose of 66 Gy/30 fr, intermediate-risk CTV 60 Gy/30 fr, and low-risk CTV 54 Gy/30 fr...
October 2018: Journal of Cancer Research and Therapeutics
Taco A van der Meulen, Jolien F van Nimwegen, Hermie J M Harmsen, Silvia C Liefers, Karin van der Tuuk, Frans G M Kroese, Marian J E Mourits, Arjan Vissink, Hendrika Bootsma
No abstract text is available yet for this article.
November 28, 2018: Annals of the Rheumatic Diseases
A Lichterfeld-Kottner, N Lahmann, U Blume-Peytavi, U Mueller-Werdan, J Kottner
AIMS AND OBJECTIVES: To measure the prevalence and severity of dry skin in the home care nursing setting in Germany and to determine demographic and health characteristics associated with skin dryness. BACKGROUND: Advanced age and skin care dependency are risk factors for the development of skin dryness. Dry skin has a negative impact on the quality of life and increases the risk for secondary cutaneous infections and other adverse skin conditions. The prevalence of dry skin in home care is unknown...
November 2018: Journal of Tissue Viability
Francesca Mercati, Margherita Maranesi, Cecilia Dall'Aglio, Linda Petrucci, Rolando Pasquariello, Federico Maria Tardella, Elena De Felice, Paola Scocco
Sheep are the most bred species in the Central Italy Apennine using the natural pastures as a trophic resource and grazing activity is fundamental to maintain the grassland biodiversity: this goal can be reached only ensuring an economical sustainability to the farmers. This study aimed to investigate the apelin/apelin receptor system in ovine mammary gland and to evaluate the differences induced by food supplementation, in order to shed light on this system function. A flock of 15 Comisana x Appenninica adult dry ewes were free to graze from June until pasture maximum flowering (MxF)...
November 28, 2018: Animals: An Open Access Journal From MDPI
Nicole Braun, Simone Thomas, Hagen Tronnier, Ulrike Heinrich
BACKGROUND: One of the most challenging and important factors of manned space missions is to keep astronauts healthy on orbit. In a study on 46 ISS crew members who were on 6-month (average) missions, skin rashes were the most self-reported event. Furthermore, among notable events, 40% were classified as skin rashes/hypersensitivities. Thus, especially skin conditions during space travel are of major clinical interest and require further research. AIMS: The aim of the study was to determine skin conditions in space flight among US and European astronauts, especially taking into account the terrestrial skin conditions as well as on-orbit skin care habits...
November 28, 2018: Skin Pharmacology and Physiology
Luciano Raúl Portero, Daniel Alonso, Federico Zannier, Martín P Vazquez, María Eugenia Farías, Wolfgang Gärtner, Virginia Helena Albarracín
"High-Altitude Andean Lakes" (HAAL) are pristine environments harboring poly-extremophilic microbes that show combined adaptations to physical and chemical stress such as large daily ambient thermal amplitude, extreme solar radiation levels, intense dryness, alkalinity, high concentrations of arsenic (up to 200 ppm) and dissolved salts. In this work, we compared the UV resistance profiles, pigment content and photoreactivation abilities of three UV-resistant bacteria isolated from distinct niches from HAAL's: i...
November 28, 2018: Photochemistry and Photobiology
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