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https://www.readbyqxmd.com/read/29457017/distinct-trichoscopic-features-of-the-sideburns-in-frontal-fibrosing-alopecia-compared-to-the-frontotemporal-scalp
#1
Jessica Cervantes, Mariya Miteva
The trichoscopic features of frontal fibrosing alopecia (FFA) have been described in the frontotemporal area, yet there is no data detailing the trichoscopic features of the sideburns, which can be the initial or exclusive area of involvement. In this retrospective cohort study, 236 trichoscopic images of the frontotemporal and sideburn area obtained via dry trichoscopy from patients with biopsy-proven FFA were examined by two independent researchers to determine the trichoscopic features of FFA in the sideburns...
January 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29441770/-determination-of-hair-shafts-by-innotyper%C3%A2-21-kit
#2
F Li, M Zhang, Y X Wang, J J Shui, M Yan, X P Jin, X J Zhu
OBJECTIVES: To explore the application value of InnoTyper® 21 kit in forensic practice. METHODS: Samples of hair shafts and saliva were collected from 8 unrelated individuals. Template DNA was extracted by AutoMate Express™ forensic DNA automatic extraction system. DNA was amplified by InnoTyper® 21 kit and AmpFℓSTR™ Identifiler™ Plus kit, respectively, and then the results were compared. RESULTS: After the amplification by InnoTyper® 21 kit, complete specific genotyping could be detected from the saliva samples, and the peak value of genotyping profiles of hair shafts without sheath cells was 57-1 219 RFU...
December 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29440852/rare-variant-of-ankyloblepharon-ectodermal-defect-cleft-lip-cleft-palate-syndrome-curly-hair-ankyloblepharon-nail-disease-syndrome
#3
Ajay Chopra, Debdeep Mitra, Renu Kandpal, Reetu Agarwal
Ankyloblepharon-ectodermal defect-cleft lip/cleft palate (AEC) syndrome is one of the variants of ectodermal dysplasia. It is an autosomal dominant disorder comprising of ankyloblepharon, ectodermal dysplasia, and cleft palate or cleft lip. In 1976, it wasfirst described by Hay and Wells, therefore also known as Hay-Wells syndrome. The characteristic feature of this syndrome is "ankyloblepharon filiforme adnatum", which refers to the partial thickness fusion of the eyelid margins. The "curly hair-ankyloblepharon-nail disease (CHAND) syndrome" is a clinical variant of AEC syndrome...
January 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29390202/-clinical-trial-regeneration-of-skin-perception-after-deep-degree-burns-in-childhood
#4
Stephan Fuchs, Gunter Klohs, Malte Kornhuber, Rainer Finke
BACKGROUND:  Cutaneous aesthesia is frequently impaired following thermal injury. The perception of pressure and touch is compromised. METHODS:  We analysed 352 patient files retrospectively and tested the perception in deep burn-damaged skin of children. The skin regions examined were classified into groups according to treatment: group 1: necrosectomy + split-thickness skin graft; group 2: epifascial necrosectomy + split-thickness skin graft; group 3: epifascial necrosectomy + Integra® + split- thickness skin graft...
February 1, 2018: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/29371649/studies-on-the-proteome-of-human-hair-identification-of-histones-and-deamidated-keratins
#5
Sunil S Adav, Roopa S Subbaiaih, Swat Kim Kerk, Amelia Yilin Lee, Hui Ying Lai, Kee Woei Ng, Siu Kwan Sze, Artur Schmidtchen
Human hair is laminar-fibrous tissue and an evolutionarily old keratinization product of follicle trichocytes. Studies on the hair proteome can give new insights into hair function and lead to the development of novel biomarkers for hair in health and disease. Human hair proteins were extracted by detergent and detergent-free techniques. We adopted a shotgun proteomics approach, which demonstrated a large extractability and variety of hair proteins after detergent extraction. We found an enrichment of keratin, keratin-associated proteins (KAPs), and intermediate filament proteins, which were part of protein networks associated with response to stress, innate immunity, epidermis development, and the hair cycle...
January 25, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29364454/circular-hairs-nomenclature-and-meanings
#6
Ana Luiza Valle Esteves, Natália Battisti Serafini, Luciana Rodino Lemes, Daniel Fernandes Melo
Trichoscopy has become an essential tool for the diagnosis of various diseases that affect the hair and scalp. Through dermatoscopy we identified a set of findings that share a circular shape of hair shafts. The objective of this study is to distinguish among the various forms of circular hairs in order to identify their peculiarities and to describe in which skin disorders they can be found.
November 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29360892/long-term-pubic-dermatitis-diagnosed-as-white-piedra
#7
James Landero
The case of a 58-year-old man with a pruritic rash involving the pubic area that had been undiagnosed for 30 years is presented. At least 15 different primary care physicians and dermatologists evaluated the patient during this time period. Multiple treatments were unsuccessful and a definitive diagnosis was not rendered. Wood lamp evaluation of the pubic area revealed hair shaft concretions that were confirmed on histologic evaluation to be white piedra (WP). The patient was successfully treated with topical ketoconazole and the eruption completely resolved...
December 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29334164/clinical-evaluation-of-a-novel-fractional-radiofrequency-device-for-hair-growth-fractional-radiofrequency-for-hair-growth-stimulation
#8
Ines Verner, Torello Lotti
AGA is a common disorder. Different treatments are available to prevent hair loss and achieve hair growth with variable results. The purpose of the present study was to evaluate the efficacy and safety of a novel fractional radiofrequency (RF) device (HairLux, Innogen Technologies Ltd., Yokneam, Israel), to prevent hair loss and induce hair growth. Twenty-five patients received 10 fractional RF treatments every 2 weeks, and were followed up 2 months after the last treatment. All patients were evaluated by global photography...
January 15, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/29240822/acne-keloidalis-nuchae-in-asian-a-single-institutional-experience
#9
Kiyong Na, Sang Ho Oh, Sang Kyum Kim
Acne keloidalis nuchae, a type of folliculitis involving the back of the neck, is common in black men, although rare cases have been reported in patients of other ethnicities. We analyzed the clinicopathological features of acne keloidalis nuchae in 17 Asians. Patients' age at the time of presentation ranged from 20 to 69 years. Most patients experienced the disease over 2 years (range, 3 months-20 years); follow-up data were available for 11 (65%) patients (range, 2-95 months). Nine (53%) patients had comorbidities, but none had a history of other skin disease or a family history of acne keloidalis nuchae...
2017: PloS One
https://www.readbyqxmd.com/read/29220540/reflectance-confocal-microscopy-evaluation-of-trichobacteriosis-axilaris
#10
Andrea Combalia, Beatriz Alejo, Susana Puig
We read with great interest the paper by Navarrete-Dechent et al recently published on the Journal of European Academy of Dermatology1 , in which the authors detail the dermoscopic findings of trichobacteriosis and highlight the importance of dermoscopy in these cases. We present the case of a 44-year-old man, who emanated an unpleasant axilary odor during a routine check-up. Close examination of the axillary hair shafts showed soft, brown to yellow irregular masses adherent to the central segment of the hairs, suggesting the diagnosis of trichobacteriosis axilaris (TA)...
December 8, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29217084/oral-phenytoin-protects-against-experimental-cyclophosphamide-chemotherapy-induced-hair-loss
#11
A Y Onaolapo, A A Adebayo, O J Onaolapo
In the current study, effects of oral phenytoin on hair growth in cyclophosphamide-treated rats were assessed with the goal of evaluating the ability of phenytoin to suppress chemotherapy-induced hair loss. Thirty-six rats were randomly assigned to six groups (1k6) of six each (n=6). In all groups, anagen was induced in flank skin of rats by depilation. On day 9 (anagen VI), rats were injected once with either distilled water (groups 1-3) or cyclophoshamide (groups 4-6). From day 10, rats in group 1 and 4 received oral vehicle (distilled water), groups 2 and 5 received oral phenytoin (50mg/kg), while groups 3 and 6 also received oral phenytoin (100mg/kg)...
December 4, 2017: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/29200764/various-wavelengths-of-light-emitting-diode-light-regulate-the-proliferation-of-human-dermal-papilla-cells-and-hair-follicles-via-wnt-%C3%AE-catenin-and-the-extracellular-signal-regulated-kinase-pathways
#12
Hong Jin Joo, Kwan Ho Jeong, Jung Eun Kim, Hoon Kang
Background: The human dermal papilla cells (hDPCs) play an important role in regulation of hair cycling and growth. Objective: The aim of this study was to investigate the effect of different wavelengths of light-emitting diode (LED) irradiation on the proliferation of cultured hDPCs and on the growth of human hair follicles (HFs) in vitro. Methods: We examined the effect of LED irradiation on Wnt/β-catenin signaling and mitogen-activated protein kinase (MAPK) pathways in hDPCs...
December 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/29186263/white-piedra-black-piedra-tinea-versicolor-and-tinea-nigra-contribution-to-the-diagnosis-of-superficial-mycosis
#13
John Verrinder Veasey, Ricardo Bertozzi de Avila, Barbara Arruda Fraletti Miguel, Laura Hitomi Muramatu
Superficial mycoses are fungal infections restricted to the stratum corneum and to the hair shafts, with no penetration in the epidermis; they are: white piedra, black piedra, tinea versicolor, and tinea nigra. This study presents images of mycological tests performed in the laboratory, as well as exams performed at the authors office, in order to improve the dermatologist's knowledge about the diagnosis of these dermatoses, which are common in many countries.
May 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29181849/the-walking-dead-sequential-nuclear-and-organelle-destruction-during-hair-development
#14
L A Jones, D P Harland, B B Jarrold, J E Connolly, M G Davis
BACKGROUND: Transition of hair shaft keratinocytes from actively respiring, nucleated cells to structural cells devoid of nucleus and cytoplasm, is key to hair production. This form of cell "death", or cornification, requires cellular organelle removal to allow the cytoplasm to become packed with keratin filament bundles that further require cross-linking to create a strong hair fibre. Although these processes are well described in epidermal keratinocytes, there is a lack of understanding of such mechanisms specifically in the hair follicle...
November 27, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29177147/exogen-hairs-in-women-with-and-without-hair-loss
#15
Marcella Guarrera, Alfredo Rebora
Contrary to the classical view of the hair cycle, in which telogen is the resting phase that precedes the release of the hair shaft, another phase has been introduced, exogen. Exogen is the phase wherein the processes for the release of the hair shaft are initiated and successfully executed. Exogen ends when the shaft is liberated. Accordingly, human hairs would be preferably released not with telogen but with exogen roots. To better understand this somehow revolutionary point and what occurs in telogen effluvium (TE) and in androgenetic alopecia (AGA), we undertook a morphological study...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29171081/in-vitro-determination-of-mexican-mestizo-hair-shaft-diameter-using-optical-coherence-tomography
#16
Maria Abril Martinez-Velasco, Marina Perper, Austin J Maddy, Jessica Cervantes, Ariel E Eber, Sebastian H Verne, Norma Elizabeth Vazquez-Herrera, Keyvan Nouri, Antonella Tosti
BACKGROUND: Mexican mestizo population has a pluriethnic mixture of Amerindian, European and African ancestry, predominant in most Latin American countries. Until now, there are no reports about hair characteristics in this population, necessary to define normal values, for hair diseases evaluation and comparison among other ethnic groups. METHODS: The VivoSight® swept-source multibeam optical coherence tomography system was used to evaluate hair diameter and shape in 30 females...
November 23, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/29156398/spontaneous-hair-follicle-germ-hfg-formation-in%C3%A2-vitro-enabling-the-large-scale-production-of-hfgs-for-regenerative-medicine
#17
Tatsuto Kageyama, Chisa Yoshimura, Dina Myasnikova, Ken Kataoka, Tadashi Nittami, Shoji Maruo, Junji Fukuda
Hair follicle morphogenesis is triggered by reciprocal interactions between hair follicle germ (HFG) epithelial and mesenchymal layers. Here, we developed a method for large-scale preparation of HFGs in vitro via self-organization of cells. We mixed mouse epidermal and mouse/human mesenchymal cells in suspension and seeded them in microwells of a custom-designed array plate. Over a 3-day culture period, cells initially formed a randomly distributed single cell aggregate and then spatially separated from each other, exhibiting typical HFG morphological features...
November 6, 2017: Biomaterials
https://www.readbyqxmd.com/read/29149771/hoxc13-and-hsp27-expression-in-skin-and-the-periodic-growth-of-secondary-fiber-follicles-from-longdong-cashmere-goats-raised-in-different-production-systems
#18
Jiqing Wang, Ping Yu, Haifang Wang, Yanyu He
This experiment was conducted to identify periodic changes in secondary follicles (SFs) over one year of extensive (grazed) and intensive (housed and fed supplement) farming of Longdong cashmere goats. One-year old goats (n = 24, 12 extensively fed and 12 intensively fed) were studied. The diameter, depth, density, activity, and ultra-structural features of SFs were assessed using light microscopy and transmission electron microscopy (TEM). HOXC13 and HSP27 expression were studied using immunohistochemistry and immunofluorescence method...
November 17, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29143381/comparing-dermoscopy-and-histological-examination-of-normal-equine-skin
#19
Lara M Tomich, Jason B Pieper, Adam W Stern
BACKGROUND: Dermoscopy is a noninvasive diagnostic technique that allows visualization of structures of the superficial dermis not visible with the naked eye. HYPOTHESIS/OBJECTIVES: To assess the usefulness and applicability of dermoscopy for evaluation of healthy equine skin. ANIMALS: Twelve healthy horses from a research herd. METHODS: Five regions (cheek, lateral neck, dorsum, flank and abdomen) were examined with contact dermoscopy using both nonpolarized and polarized light at both 17-fold and 24-fold magnification...
November 15, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/29118524/collision-tumor-between-trichofolliculoma-and-melanocytic-nevus
#20
Christel Bolte, Roberto Cullen, Ivo Sazunic
Trichofolliculoma (TF) is a hamartomatous hair follicle-related tumor, clinically described as a dome-shaped papule with a central pore crossed by one or more silky white hairs. Histologically, it described as a cystic cavity containing keratinous debris, hair shaft fragments, and numerous hair follicles arising from its linings. Collision or compound tumors are a coexistence of two or more identifiable tumors in the same lesion. We present a case of a 47-year-old man with a lesion on his left cheek clinically characterized as a TF...
October 2017: International Journal of Trichology
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