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Bahlol Rahimi, Hamed Nadri, Hadi Lotfnezhad Afshar, Toomas Timpka
BACKGROUND:  One common model utilized to understand clinical staff and patients' technology adoption is the technology acceptance model (TAM). OBJECTIVE:  This article reviews published research on TAM use in health information systems development and implementation with regard to application areas and model extensions after its initial introduction. METHOD:  An electronic literature search supplemented by citation searching was conducted on February 2017 of the Web of Science, PubMed, and Scopus databases, yielding a total of 492 references...
July 2018: Applied Clinical Informatics
Kyle Freischlag, Keven Ji, Reed W Kamyszek, Harold J Leraas, Lindsey A Olivere, Liana Gefter, Barry Mann, John Migaly, Elisabeth T Tracy
OBJECTIVE: The Health Career Academy (HCA) is a national program which provides a structure to introduce underserved high school students to healthcare careers. Utilizing the HCA framework, we adapted the curriculum to emphasize surgical cases and invited physicians to enrich the learning experience. DESIGN, SETTING, AND PARTICIPANTS: Medical students adapted a surgical case-based learning (CBL) curriculum at a local high school serving students from a primarily ethnic minority and low-income community (61% Black, 20% Hispanic; 58% free or reduced lunch)...
August 12, 2018: Journal of Surgical Education
Claudia Espinosa, Ravi Jhaveri, A Sidney Barritt
PURPOSE: Hepatitis C, a chronic disease with deadly consequences, is no longer predominantly a disease of older people. METHODS: A limited search was conducted of the relevant literature on 2 topics: (1) the impact of hepatitis C on infants exposed by vertical transmission; and (2) the impact of hepatitis C infection on infected children and adolescents. The findings were supplemented by the first-hand experience of the authors. FINDINGS: Young people, including women of childbearing age, infants, children, and adolescents, are being especially affected by hepatitis C infection secondary to the intravenous drug use and opioid epidemic...
August 11, 2018: Clinical Therapeutics
Gerald B Fogarty, Angela Hong, Alex Economides, Pascale Guitera
Lentigo maligna (LM) is a form of melanoma in situ that occurs on exposed, sun-damaged skin; LM can progress to invasive melanoma. Conventional surgical treatment is the preferred management option as it is usually a one-treatment episode and generates a histopathology report that records completion of excision. Some patients may not be surgical candidates due to comorbidities, patient preference, impact on function, and cosmesis or they have failed surgery with a positive margin. Other therapies, including radiotherapy (RT) and topical medicines, may then become appropriate...
2018: Dermatology Research and Practice
Manuel E Jimenez, Shawna V Hudson, Daniel Lima, Benjamin F Crabtree
In-depth interviews allow for rich exploration of stakeholders' experiences. Preparation for in-depth interviews generally consists of literature reviews and researchers' review of their own culture and understanding of a topic. We supplemented these strategies with serial "ethnographic interviews" with a single community leader to enhance our preparation for community-based in-depth interviews with Latina, immigrant, Spanish-speaking mothers and to facilitate stakeholder engagement in a research project...
August 12, 2018: Qualitative Health Research
Souska Zandi, Bahram Bodaghi, Justus G Garweg
PURPOSE: To define a clinically tailored therapeutic strategy for the treatment of viral anterior uveitis (VAU). METHODS: A PubMed search spanning the past 5 years was conducted using the MesH-terms "viral anterior uveitis" and "therapy." RESULTS: The herpes simplex virus (HSV), the varicella zoster virus (VZV), and the cytomegalovirus (CMV) are the predominant pathogens in VAU. Other viruses, including rubella, chikungunya, and zika, have been linked with distinct forms of the disease...
August 10, 2018: Ocular Immunology and Inflammation
Caitlin Yee, Katie Wang, Rashi Asthana, Leah Drost, Henry Lam, Justin Lee, Danny Vesprini, Eric Leung, Carlo DeAngelis, Edward Chow
Radiation dermatitis is a common side effect of radiotherapy. Radiation dermatitis has been investigated for decades, and many approaches have been proposed to limit its incidence and severity. The purpose of the present systematic review was to summarize the approaches and findings of studies testing various methods for management of radiation dermatitis in breast cancer patients. Medline, Cochrane, and Embase were searched for studies pertaining to radiation-induced skin toxicity in breast cancer patients...
July 4, 2018: Clinical Breast Cancer
Zhe He, Cui Tao, Jiang Bian, Rui Zhang, Jingshan Huang
In this editorial, we first summarize the 2nd International Workshop on Semantics-Powered Data Analytics (SEPDA 2017) held on November 13, 2017 in Kansas City, Missouri, U.S.A., and then briefly introduce 13 research articles included in this supplement issue, covering topics such as Semantic Integration, Deep Learning, Knowledge Base Construction, and Natural Language Processing.
July 23, 2018: BMC Medical Informatics and Decision Making
Noor Safiza Mohamad Nor, Rashidah Ambak, Tahir Aris
BACKGROUND: The national prevalence of overweight and obesity in Malaysia has been increasing in the past 10 years and many efforts have been implemented by the Malaysian government to combat obesity problem among the Malaysian population. The aim of this paper was to describe the background of the My Body is Fit and Fabulous at home (MyBFF@home) study (Phase II). DISCUSSION: The MyBFF@home (Phase II) was a quasi-experimental study and it was conducted among overweight and obese housewives living in the urban areas in Malaysia...
July 19, 2018: BMC Women's Health
Christabel Owens, Mary Carter, Deborah Shenton, Richard Byng, Cath Quinn
In an effort to encourage men with experience of being subject to the criminal justice system to contribute to focus group discussions on the sensitive topic of mental health, while also doing our utmost to protect them from discomfort or risk of exploitation, we used a novel technique involving the creation of a fictional character, supplemented by an audio-recorded vignette. We studied the role played by this technique in achieving our stated aims of "engaging without exposing." In this article, we report on the use of this technique in three focus groups, showing how in very different ways it shaped the interaction between participants and generated crucial insights into the lives and service needs of each group...
August 1, 2018: Qualitative Health Research
Feng Cheng, Yifang Wang, Jiayin Zhao, Xixian Wu
The relationship between mothers' negative emotional expression and preschoolers' negative emotional regulation has been a topic of debate. Studies have confirmed the unique effect of maternal education on children's emotional regulation. Further understanding of the role of maternal educational attainment in the relationship between mothers' emotional expression and children's emotional regulation strategies will help us better explain the possible reasons for the differences in children's emotional regulation abilities...
July 28, 2018: Child Abuse & Neglect
Martha J Ignaszewski, Bruce Waslick
OBJECTIVES: Antidepressant treatment for major depressive disorder (MDD) has been a topic of continued interest with a number of placebo randomized-controlled trials (RCTs) being published in the past decade. We review the updated literature since the 2007 Bridge meta-analysis, and reassess safety data looking at signals of treatment-emergent suicidality with the Columbia Suicide Severity Rating Scale (CSSR-S). METHODS: PubMed literature review was performed searching for RCTs published since the 2007 article and supplemented with manual search...
July 31, 2018: Journal of Child and Adolescent Psychopharmacology
Geronimo Jimenez, Woan Shin Tan, Amrit K Virk, Chan Kee Low, Josip Car, Andy Hau Yan Ho
OBJECTIVE: To provide an overview of the current state of research of advance care planning (ACP), highlighting most studied topics, publication time, quality of studies and reported outcomes, and to identify gaps to improve ACP receptivity, utilization, implementation, and outcomes. METHOD: Cochrane methodology for conducting overviews of systematic reviews. Study quality was assessed using a modified version of the Assessing the Methodological Quality of Systematic Reviews tool...
July 30, 2018: Palliative & Supportive Care
Tahereh Gholipur-Shahraki, Awat Feizi, Mojgan Mortazavi, Shirinsadat Badri
Protein energy malnutrition is a common problem in patients with chronic kidney disease (CKD). Scattered reports indicate that supplementation of Carnitine may improve patients' clinical symptoms, with significant improvement in nutritional parameters. This systematic review was done to document the evidences of Carnitine effects in nutritional status of CKD patients. Peer-reviewed RCTs on Carnitine administration at any dose in CKD patients with at least four weeks of follow-up were including in the meta-analysis...
April 2018: Journal of Research in Pharmacy Practice
Weng I Choi, Honghao Shi, Ying Bian, Hao Hu
Facing difficulties like increasing health burden and health inequity, China government started to promote commercial health insurance (CHI) in recent decades. Several policies and announcement have been issued to build up a favorable environment for development of commercial health insurance. Meanwhile, scholar tried to investigate the related issues in purpose to further improve the situation in China. Therefore, we performed this systematic review in order depict a comprehensive picture on the current evidence-based researches of CHI in China...
2018: BioMed Research International
Laura E Downie, Anne Gad, Chinn Yi Wong, John Henry V Gray, Weiguang Zeng, David C Jackson, Algis J Vingrys
Purpose: To assess the efficacy of anti-inflammatory approaches, comprising a topical corticosteroid and omega-3 supplements, for modulating the inflammatory overlay associated with contact lens discomfort (CLD). Methods: This randomized controlled trial involved 72 adults with CLD, randomized (1:1:1:1) to one of the following: placebo (oral olive oil), oral fish oil (900 mg/d eicosapentaenoic acid [EPA] + 600 mg/d docosohexaenoic acid [DHA]), oral combined fish+flaxseed oils (900 mg/d EPA + 600 mg/d DHA + 900 mg/d alpha-linolenic acid), or omega-3 eye-drops (0...
July 2, 2018: Investigative Ophthalmology & Visual Science
Amy C Orben, Augustin Mutak, Fabian Dablander, Marlene Hecht, Jakub M Krawiec, Natália Valkovičová, Daina Kosīte
Social media is radically altering the human social landscape. Before the internet era, human interaction consisted chiefly of direct and reciprocal contact, yet with the rise of social media, the passive consumption of other users' information is becoming an increasingly popular pastime. Passive consumption occurs when a user reads the posts of another user without interacting with them in any way. Previous studies suggest that people feel more connected to an artificial person after passively consuming their Facebook posts...
2018: Frontiers in Psychology
Ulrike Trautvetter, Bianka Ditscheid, Gerhard Jahreis, Michael Glei
Phosphates are associated with negative physiological effects. The objectives of this publication were to compare differential effects of supplementation with calcium phosphate or phosphate alone in healthy humans. Four adult human studies were conducted with pentacalcium hydroxy-trisphosphate supplementation (CaP; 90 subjects) and their data were pooled for assessment. For literature search; PubMed and ISI Web of Knowledge were used and 21 items were assigned to three main topics. The pooled study results show that following CaP supplementation, faecal calcium and phosphorus and urinary calcium were increased, blood lipids were positively modulated, and faecal bile acids were increased, as compared with placebo...
July 20, 2018: Nutrients
Christina Bothou, Alexis Alexopoulos, Eleni Dermitzaki, Kleanthis Kleanthous, Anastasios Papadimitriou, George Mastorakos, Dimitrios T Papadimitriou
Atopic dermatitis (AD) is a chronic inflammatory disease affecting children and adolescence. The traditional therapeutic options for AD, including emollients topically and immune modulatory agents systemically focusing on reducing skin inflammation and restoring the function of the epidermal barrier, are proven ineffective in many cases. Several studies have linked vitamin D supplementation with either a decreased risk to develop AD or a clinical improvement of the symptoms of AD patients. In this report, we present a girl with severe AD who under adequate supplementation with cholecalciferol was treated with calcitriol and subsequently with paricalcitol...
2018: Case Reports in Pediatrics
Stephen Bolsin, Jenny Carter, Aileen Kitson, Donna Walter, Stephen Roberts
Clinical engagement has supplemented clinical governance in healthcare to strengthen the contribution of medical professionals to the assessment of clinical outcomes for patients. Assessments of clinical engagement have, until now, been qualitative; this case study introduces the concept of quantitative assessment of clinical engagement by measuring the number of patients managed according to specialist society guidelines. Such an assessment engages all staff (medical, nursing, allied health and pharmacy) involved in patients receiving treatment according to such guidelines and provides an assessment of individual and organisational compliance with those guidelines...
July 19, 2018: Australian Health Review: a Publication of the Australian Hospital Association
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