keyword
MENU ▼
Read by QxMD icon Read
search

Igf uterus

keyword
https://www.readbyqxmd.com/read/28986927/effects-of-phyto-oestrogen-quercetin-on-productive-performance-hormones-reproductive-organs-and-apoptotic-genes-in-laying-hens
#1
J X Yang, M T Chaudhry, J Y Yao, S N Wang, B Zhou, M Wang, C Y Han, Y You, Y Li
Quercetin, a polyphenolic flavonoid with diverse biological activities including anti-inflammatory and antiviral, inhibits lipid peroxidation, prevents oxidative injury and cell death. The purpose of the research was to investigate the effect of quercetin on productive performance, reproductive organs, hormones and apoptotic genes in laying hens between 37 and 45 weeks of age, because of the structure and oestrogenic activities similar to 17β-oestradiol. The trial was conducted using 240 Hessian laying hens (37 weeks old), housed in wire cages with two hens in each cage...
October 6, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28888896/hormonal-profile-and-follicular-dynamics-concurrent-with-cidr-and-insulin-modified-ovsync-tai-programs-and-their-impacts-on-the-fertility-response-in-buffaloes
#2
A A Ramoun, A M Emara, B A Heleil, S A Darweish, H A Abou-Ghait
Fifty one cyclic Egyptian buffaloes were used to study the hormonal profile and follicular dynamics concurrent with CIDR and insulin modified Ovsync TAI programs and their impacts on the consequent fertility responses. The buffaloes were randomly assigned into 3 ovulation synchronization protocols: Ovsync-alone (n = 13, control) CIDR-sync (n = 20) and Insulin-sync (n = 18). Ovsync-alone protocol consisted of two im injections of 20 μg bueserlin (GnRHa) on Day 0 (GnRH 1) and on Day 9 (GnRH 2) with an im injection of 500 μg of cloprostenol sodium (PGF2 α) on Day 7...
August 19, 2017: Theriogenology
https://www.readbyqxmd.com/read/28682900/doege-potter-syndrome-a-review-of-the-literature-including-a-new-case-report
#3
REVIEW
Guiyan Han, Zhimin Zhang, Xingbin Shen, Kunpeng Wang, Yang Zhao, Jianqiu He, Yu Gao, Xiujie Shan, Guohua Xin, Chunhui Li, Xiaoyan Liu
RATIONALE: We reviewed 76 published cases of Doege-Potter syndrome, and non-islet cell tumor hypoglycemia (NICTH) secondary to a solitary fibrous tumor (SFT) between 1989 and 2016, to study disease pathogenesis, diagnosis, and treatment of this rare paraneoplastic disease. Further, we report 1 new case of a patient presenting with Doege-Potter syndrome. PATIENTS CONCERNS: The tumors originated from the pleural cavity, lung, pelvis, liver, retroperitoneum, kidney, mediastinal, the sella, uterus, bladder, intestine, mandibular, and the thigh...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28467127/markers-of-obesity-and-growth-in-preeclamptic-and-normotensive-pregnant-women
#4
S Kharb, J Bala, S Nanda
The objective of the study was to analyse leptin, IGF-1, Apo A, lipoproteins, haem oxygenase-1 (HO-1) in maternal sera and venous umbilical cord sera of newborn babies of 25 preeclamptics (group II), and 25 normotensive pregnant women (group I) as markers of obesity and growth in preeclamptic and normotensive pregnant women. Apo A I and II levels were estimated by competitive immunoassay using direct chemiluminiscence technology. Haem oxygenase-1 (HO-1), leptin and IGF-1 were analysed by ELISA. Maternal and cord blood levels of homocysteine, folic acid, lipid profile (namely, total cholesterol, triglycerides, LDL-C, VLDL-C and HDL-C), Haem oxygenase 1 were higher in preeclamptic women as compared to normotensive pregnant women...
May 3, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28428227/mechanisms-in-endocrinology-the-multiple-facets-of-ghrh-gh-igf-i-axis-lessons-from-lifetime-untreated-isolated-gh-deficiency-due-to-a-ghrh-receptor-gene-mutation
#5
REVIEW
Manuel H Aguiar-Oliveira, Anita H O Souza, Carla R P Oliveira, Viviane C Campos, Luíz A Oliveira-Neto, Roberto Salvatori
Twenty years ago, we described kindred of 105 individuals with isolated GH deficiency (IGHD) in Itabaianinha County, in northeast Brazil, carrying a homozygous mutation in the GH-releasing hormone receptor gene. These subjects exhibit markedly reduced GH responsiveness to stimulatory tests, and anterior pituitary hypoplasia. Serum concentrations of IGF-I, IGF binding protein type 3 and the acid-labile subunit are markedly reduced, with a lesser reduction of IGF-II. The most striking physical findings of these IGHD individuals are the proportionate short stature, doll facies, high-pitched voice and visceral obesity with reduced fat-free mass...
August 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27697446/coadministration-of-puerarin-low-dose-and-zinc-attenuates-bone-loss-and-suppresses-bone-marrow-adiposity-in-ovariectomized-rats
#6
Hao Liu, Wei Li, Xiyuan Ge, Shengnan Jia, Binbin Li
AIMS: Puerarin is a phytoestrogen that shows osteogenic effects. Meanwhile, zinc stimulates bone formation and inhibits bone resorption. The study aims to investigate the effects of coadministration of puerarin (low dose) and zinc on bone formation in ovariectomized rats. MATERIALS AND METHODS: Co-administration or use alone of puerarin (low dose) and/or zinc were gavaged in OVX rats. The estrogen-like effects were detected by the uterus weight, the histologic observation and the IGF-1 protein expression...
December 1, 2016: Life Sciences
https://www.readbyqxmd.com/read/27514375/transcriptomics-of-liver-and-muscle-in-holstein-cows-genetically-divergent-for-fertility-highlight-differences-in-nutrient-partitioning-and-inflammation-processes
#7
Bruce Moran, Sean B Cummins, Christopher J Creevey, Stephen T Butler
BACKGROUND: The transition between pregnancy and lactation is a major physiological change for dairy cows. Complex systemic and local processes involving regulation of energy balance, galactopoiesis, utilisation of body reserves, insulin resistance, resumption of oestrous cyclicity and involution of the uterus can affect animal productivity and hence farm profitability. Here we used an established Holstein dairy cow model of fertility that displayed genetic and phenotypic divergence in calving interval...
August 11, 2016: BMC Genomics
https://www.readbyqxmd.com/read/26899592/effects-of-oriental-medicine-kyung-ok-ko-on-uterine-abnormality-in-hyperandrogenized-rats
#8
Min Jung Lee, Minhee Jang, Chun-Sik Bae, Kyoung-Sun Park, Hak-Jae Kim, Sanghyun Lee, Sang Won Lee, Young Ock Kim, Ik-Hyun Cho
A traditional herbal prescription Kyung-Ok-Ko (KOK), composed of Rehmannia glutinosa Liboschitz var. purpurae, Lycium chinense, Aquilaria agallocha, Poria cocos, Panax ginseng, and honey, has been widely used in Oriental medicine as an invigorant for age-related diseases, such as amnesia and stroke. However, the beneficial value of KOK on uterine dysfunction related to hyperandrogenism is largely unknown. We investigated the effect of KOK (2.0 g/kg/day, per os) on endometrial abnormalities in a dehydroepiandrosterone (DHEA, subcutaneous)-induced polycystic ovary syndrome (PCOS) rat model...
December 2016: Rejuvenation Research
https://www.readbyqxmd.com/read/26787031/effects-of-a-combination-therapy-of-sclerostin-antibody-iii-and-raloxifene-on-bone-formation-markers-in-ovariectomized-rats
#9
Hayam Ibrahim Gad Allam
OBJECTIVE: To determine the systemic effect of sclerostin monoclonal antibody (Scl-AbIII) administration on markers of bone formation and compare it with a combination of sclerostin antibody and raloxifene. STUDY DESIGN: Experimental study. PLACE AND DURATION OF STUDY: Medical College Animal House at King Khaled University Hospital, Riyadh, Saudi Arabia, from January to November 2014. METHODOLOGY: Forty-five female rats were divided into 5 groups equally; 1 control group and 4 groups of ovariectomized (OVX) rats: control OVX rats and OVX rats treated by Scl-AbIII, raloxifene or Scl-AbIII+raloxifene one month after ovariectomy, continued for 4 weeks...
January 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/26745663/mechanisms-of-trophoblast-migration-endometrial-angiogenesis-in-preeclampsia-the-role-of-decorin
#10
REVIEW
Peeyush K Lala, Pinki Nandi
The objective of the present review is to synthesize the information on the cellular and molecular players responsible for maintaining a homeostatic balance between a naturally invasive human placenta and the maternal uterus in pregnancy; to review the roles of decorin (DCN) as a molecular player in this homeostasis; to list the common maladies associated with a break-down in this homeostasis, resulting from a hypo-invasive or hyper-invasive placenta, and their underlying mechanisms. We show that both the fetal components of the placenta, represented primarily by the extravillous trophoblast, and the maternal component represented primarily by the decidual tissue and the endometrial arterioles, participate actively in this balance...
March 3, 2016: Cell Adhesion & Migration
https://www.readbyqxmd.com/read/26608222/autocrine-embryotropins-revisited-how-do-embryos-communicate-with-each-other-in-vitro-when-cultured-in-groups
#11
Eline Wydooghe, Leen Vandaele, Sonia Heras, Petra De Sutter, Dieter Deforce, Luc Peelman, Catharina De Schauwer, Ann Van Soom
In the absence of the maternal genital tract, preimplantation embryos can develop in vitro in culture medium where all communication with the oviduct or uterus is absent. In several mammalian species, it has been observed that embryos cultured in groups thrive better than those cultured singly. Here we argue that group-cultured embryos are able to promote their own development in vitro by the production of autocrine embryotropins that putatively serve as a communication tool. The concept of effective communication implies an origin, a signalling agent, and finally a recipient that is able to decode the message...
February 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/26559469/gene-expression-profiles-of-some-cytokines-growth-factors-receptors-and-enzymes-gm-csf-ifn%C3%AE-mmp-2-igf-ii-egf-tgf-%C3%AE-igf-iir-during-pregnancy-in-the-cat-uterus
#12
Ozgecan Korkmaz Agaoglu, Ali Reha Agaoglu, Aydin Guzeloglu, Selim Aslan, Ercan Kurar, Seyit Ali Kayis, Sabine Schäfer-Somi
Early pregnancy is one of the most critical periods of pregnancy, and many factors such as cytokines, enzymes, and members of the immune system have to cooperate in a balanced way. In the present study, the gene expression profiles of factors associated with pregnancy such as EGF, transforming growth factor beta, granulocyte-macrophage colony-stimulating factor, interferon gamma, insulin-like growth factor 2, insulin-like growth factor 2 receptor, and matrix metalloproteinase 2 were analyzed in uterine tissues of female cats...
March 1, 2016: Theriogenology
https://www.readbyqxmd.com/read/26417939/adam12-and-papp-a-candidate-regulators-of-trophoblast-invasion-and-first-trimester-markers-of-healthy-trophoblasts
#13
REVIEW
Julian K Christians, Alexander G Beristain
Proper placental development and function is crucial for a healthy pregnancy, and there has been substantial research to identify markers of placental dysfunction for the early detection of pregnancy complications. Low first-trimester levels of a disintegrin and metalloproteinase 12 (ADAM12) and pregnancy-associated plasma protein-A (PAPP-A) have been consistently associated with the subsequent development of preeclampsia and fetal growth restriction. These molecules are both metalloproteinases secreted by the placenta that cleave insulin-like growth factor binding proteins (IGFBPs), although ADAM12 also has numerous other substrates...
March 3, 2016: Cell Adhesion & Migration
https://www.readbyqxmd.com/read/25892958/the-histone-h3k9-demethylase-kdm3b-is-required-for-somatic-growth-and-female-reproductive-function
#14
Zhaoliang Liu, Xian Chen, Suoling Zhou, Lan Liao, Rui Jiang, Jianming Xu
Kdm3b is a Jumonji C domain-containing protein that demethylates mono- and di-methylated lysine 9 of histone H3 (H3K9me1 and H3K9me2). Although the enzyme activity of Kdm3b is well characterized in vitro, its genetic and physiological function remains unknown. Herein, we generated Kdm3b knockout (Kdm3bKO) mice and observed restricted postnatal growth and female infertility in these mice. We found that Kdm3b ablation decreased IGFBP-3 expressed in the kidney by 53% and significantly reduced IGFBP-3 in the blood, which caused an accelerated degradation of IGF-1 and a 36% decrease in circulating IGF-1 concentration...
2015: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/25666754/developmental-exposure-to-bisphenol-a-alters-the-differentiation-and-functional-response-of-the-adult-rat-uterus-to-estrogen-treatment
#15
Lucía Vigezzi, Verónica L Bosquiazzo, Laura Kass, Jorge G Ramos, Mónica Muñoz-de-Toro, Enrique H Luque
We assessed the long-term effect of perinatal exposure to bisphenol A (BPA) on the rat uterus and the uterine response to estrogen (E2) replacement therapy. BPA (0.5 or 50μg/kg/day) was administered in the drinking water from gestational day 9 until weaning. We studied the uterus of female offspring on postnatal day (PND) 90 and 360, and the uterine E2 response on PND460 (PND460-E2). On PND90, BPA-exposed rats showed altered glandular proliferation and α-actin expression. On PND360, BPA exposure increased the incidence of abnormalities in the luminal and glandular epithelium...
April 2015: Reproductive Toxicology
https://www.readbyqxmd.com/read/25486203/expression-regulation-and-function-of-egr1-during-implantation-and-decidualization-in-mice
#16
Bin Guo, Xue-Chao Tian, Dang-Dang Li, Zhan-Qing Yang, Hang Cao, Qiao-Ling Zhang, Ju-Xiong Liu, Zhan-Peng Yue
Abstract Early growth response gene 1 (Egr1), a zinc finger transcriptional factor, plays an important role in regulating cell proliferation, differentiation and angiogenesis. Current data have shown that Egr1 is involved in follicular development, ovulation, luteinization and placental angiogenesis. However, the expression, regulation and function of Egr1 in mouse uterus during embryo implantation and decidualization are poorly understood. Here we showed that Egr1 was strongly expressed in the subluminal stroma surrounding the implanting blastocyst on day 5 of pregnancy...
2014: Cell Cycle
https://www.readbyqxmd.com/read/25476824/serum-insulin-like-growth-factor-1-and-c-reactive-protein-concentrations-before-and-after-ovariohysterectomy-in-bitches-with-pyometra
#17
Roman Dąbrowski, Marek Szczubiał, Krzysztof Kostro, Władysław Wawron, Jose J Ceron, Asta Tvarijonaviciute
Pyometra is one of the most common diseases of the reproductive system in bitches. The inflammatory processes occurring in the uterus result in changes in concentrations of numerous serum biomarkers, which are used for monitoring the postoperative period. The aim of the present report was to study the evolution of serum levels of insulin-like growth factor-1 (IGF-1) and C-reactive protein (CRP) in bitches suffered from pyometra and after ovariohysterectomy in comparison with the control group of healthy dogs submitted to the surgery...
March 1, 2015: Theriogenology
https://www.readbyqxmd.com/read/25031358/the-lif-mediated-molecular-signature-regulating-murine-embryo-implantation
#18
Gracy X Rosario, Eiichi Hondo, Jae-Wook Jeong, Rafidah Mutalif, Xiaoqian Ye, Li Xuan Yee, Colin L Stewart
The establishment of a receptive uterus is the prime requirement for embryo implantation. In mice, the E2-induced cytokine leukemia inhibitory factor (LIF) is essential in switching the uterine luminal epithelium (LE) from a nonreceptive to a receptive state. Here we define the LIF-mediated switch using array analysis and informatics to identify LIF-induced changes in gene expression and annotated signaling pathways specific to the LE. We compare gene expression profiles at 0, 1, 3, and 6 h, following LIF treatment...
September 2014: Biology of Reproduction
https://www.readbyqxmd.com/read/24728609/nutrient-restriction-induces-failure-of-reproductive-function-and-molecular-changes-in-hypothalamus-pituitary-gonadal-axis-in-postpubertal-gilts
#19
Dongsheng Zhou, Yong Zhuo, Lianqiang Che, Yan Lin, Zhengfeng Fang, De Wu
People on a diet to lose weight may be at risk of reproductive failure. To investigate the effects of nutrient restriction on reproductive function and the underlying mechanism, changes of reproductive traits, hormone secretions and gene expressions in hypothalamus-pituitary-gonadal axis were examined in postpubertal gilts at anestrus induced by nutrient restriction. Gilts having experienced two estrus cycles were fed a normal (CON, 2.86 kg/d) or nutrient restricted (NR, 1 kg/d) food regimens to expect anestrus...
July 2014: Molecular Biology Reports
https://www.readbyqxmd.com/read/24680661/transplantation-of-bone-marrow-mesenchymal-stem-cells-on-collagen-scaffolds-for-the-functional-regeneration-of-injured-rat-uterus
#20
Lijun Ding, Xin'an Li, Haixiang Sun, Jing Su, Nacheng Lin, Bruno Péault, Tianran Song, Jun Yang, Jianwu Dai, Yali Hu
Serious injuries of endometrium in women of reproductive age are often followed by uterine scar formation and a lack of functional endometrium predisposing to infertility or miscarriage. Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown great promise in clinical applications. In the present study, BM-MSCs loaded onto degradable collagen membranes were constructed. Collagen membranes provided 3-dimmensional architecture for the attachment, growth and migration of rat BM-MSCs and did not impair the expression of the stemness genes...
June 2014: Biomaterials
keyword
keyword
16795
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"