keyword
MENU ▼
Read by QxMD icon Read
search

Pneumocystosis

keyword
https://www.readbyqxmd.com/read/30013402/diagnostic-discrepancy-between-bronchoalveolar-lavage-and-transbronchial-biopsy-from-bronchoscopies-of-hiv-patients-with-pneumonia-toward-an-integral-diagnosis
#1
Olivia Sánchez-Cabral, Dina Martínez-Mendoza, Ángel Paul Flores-Bello, José Arturo Martínez-Orozco, Rosa María Rivera-Rosales, César Luna-Rivero, Patricio Santillán-Doherty, Gustavo Reyes-Terán
Background: The key diagnostic method for the evaluation of lung diseases associated with HIV infection is bronchoscopy, with bronchoalveolar lavage (BAL) being the most commonly used sampling technique. Transbronchial biopsy (TBB) is often complementary. Setting: This is a retrospective cross-sectional study to determine the diagnostic usefulness of bronchoscopy with simultaneous samples obtained through BAL and TBB in HIV-infected patients with pneumonia at the National Institute of Respiratory Diseases Ismael Cosío Villegas...
2018: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/29848085/risk-of-opportunistic-infections-in-patients-treated-with-alemtuzumab-for-multiple-sclerosis
#2
REVIEW
Antonio Riccardo Buonomo, Emanuela Zappulo, Giulio Viceconte, Riccardo Scotto, Guglielmo Borgia, Ivan Gentile
Alemtuzumab is a monoclonal anti CD-52 antibody recently approved for use in relapsing-remitting multiple sclerosis(MS). Given that the targeted antigen is primarily expressed on B and T lymphocytes, the administration of this biological drug is associated with rapid but protracted peripheral lymphopenia. Areas covered: The impact on infective risk of this immune impairment is still to be fully understood. In this review, we attempt to summarize all the available literature concerning opportunistic infections occurring in patients with MS receiving alemtuzumab...
July 2018: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/29789160/pneumocystosis-and-quantitative-pcr
#3
N Issa, F Gabriel, G Baulier, G Mourissoux, I Accoceberry, O Guisset, F Camou
OBJECTIVE: Pneumocystis pneumonia (PCP) is now predominantly observed in immunosuppressed non-HIV-infected patients. The sensitivity of the PCR is here higher than direct examination (DE) of respiratory secretions because the infection is caused by a lower inoculum of Pneumocystis jirovecii (P. jirovecii). The objective of our retrospective study was to assess the contribution of quantitative PCR (qPCR) in the diagnosis of PCP. PATIENTS AND METHODS: All patients hospitalized for PCP suspicion with a positive qPCR were included...
May 19, 2018: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/29588907/disseminated-toxoplasmosis-in-a-patient-with-advanced-acquired-immunodeficiency-syndrome
#4
Ricardo Garcia Pastorello, Anderson da Costa Lino Costa, Marcio Valente Yamada Sawamura, Antonio Carlos Nicodemo, Amaro Nunes Duarte-Neto
Extracerebral toxoplasmosis, with pulmonary involvement and shock, is a rare form of toxoplasmosis in patients with advanced AIDS. It can mimic pneumocystosis, histoplasmosis, and disseminated tuberculosis, and should be considered in the differential diagnosis of causes of respiratory failure and fulminant disease in this group of individuals, especially in areas where the Toxoplasma gondii infection is highly prevalent and in those without proper use of antimicrobial prophylaxis. We report the case of a 46-year-old male patient who presented to the emergency department with uremia, requiring urgent dialysis...
January 2018: Autopsy & case reports
https://www.readbyqxmd.com/read/29534500/burden-of-severe-fungal-infections-in-burkina-faso
#5
Sanata Bamba, Adama Zida, Ibrahim Sangaré, Mamoudou Cissé, David W Denning, Christophe Hennequin
Because of the limited access to more powerful diagnostic tools, there is a paucity of data regarding the burden of fungal infections in Burkina Faso. The aim of this study was to estimate the incidence and prevalence of serious fungal infections in this sub-Saharan country. We primarily used the national demographic data and performed a PubMed search to retrieve all published papers on fungal infections from Burkina Faso and its surrounding West African countries. Considering the prevalence of HIV infection (0...
March 11, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29379705/the-important-role-of-co-infections-in-patients-with-aids-and-progressive-disseminated-histoplasmosis-pdh-a-cohort-from-colombia
#6
Diego H Caceres, Ángela M Tobón, Ángela Restrepo, Tom Chiller, Beatriz L Gómez
A total of 23/45 (51%) patients with AIDS and histoplasmosis from Medellín, Colombia had other infections. Tuberculosis was the most common (n = 16/23, 70%). Pneumocystosis and cryptococcosis were found in three patients each (13%), bacterial infection and cytomegalovirus occurred each in two patients (9%) while toxoplasmosis, herpes virus and esophageal candidiasis were recorded in one patient each (4%). Of all co-infected patients, 18/23 (78%) had one, four (17%) had two and one (4%) had three additional opportunistic infections...
March 2018: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/29202739/the-lung-microbiome-in-patients-with-pneumocystosis
#7
J Kehrmann, B Veckollari, D Schmidt, O Schildgen, V Schildgen, N Wagner, M Zeschnigk, L Klein-Hitpass, O Witzke, J Buer, J Steinmann
BACKROUND: Pneumocystis jirovecii pneumonia (PCP) is an opportunistic fungal infection that is associated with a high morbidity and mortality in immunocompromised individuals. In this study, we analysed the microbiome of the lower respiratory tract from critically ill intensive care unit patients with and without pneumocystosis. METHODS: Broncho-alveolar fluids from 65 intubated and mechanically ventilated intensive care unit patients (34 PCP+ and 31 PCP- patients) were collected...
December 4, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29145787/pneumocystosis-in-dogs-meta-analysis-of-43-published-cases-including-clinical-signs-diagnostic-procedures-and-treatment
#8
REVIEW
Christiane Weissenbacher-Lang, Andrea Fuchs-Baumgartinger, Abigail Guija-De-Arespacochaga, Andrea Klang, Herbert Weissenböck, Frank Künzel
We evaluated 43 published cases of dogs with confirmed Pneumocystis infection regarding the value of clinical parameters indicating the presence of the disease as well as tools for the detection of the pathogen. The assessed parameters included clinical signs, laboratory findings, results of thoracic radiography, autopsy, histopathology, methods for the detection of Pneumocystis, as well as medical therapy. Pneumocystosis was diagnosed most often in certain breeds (Cavalier King Charles Spaniel, Miniature Dachshund) with a predisposition for impaired immunity...
January 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29125373/use-of-1-3-%C3%AE-d-glucan-in-invasive-fungal-diseases-in-hematology-patients
#9
REVIEW
Daniele Roberto Giacobbe, Valerio Del Bono, Claudio Viscoli, Malgorzata Mikulska
Invasive fungal diseases (IFD) remain a leading cause of morbidity and mortality in hematology patients. Within a diagnostic-driven approach, the use of the serum (1,3)-ß-D-glucan (BDG) test represents a valid tool for the early diagnosis and treatment of IFD. Areas covered: The available literature on the use of BDG in hematology patients was systematically retrieved. Then, it was reviewed and discussed, to identify key issues pertaining to a clinically-oriented narrative presentation of the topic. Expert commentary: The use of BDG in hematology patients at risk for invasive aspergillosis (IA) is secondary to the use of galactomannan...
December 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28774701/fungal-infections-in-hiv-aids
#10
REVIEW
Andrew H Limper, Antoine Adenis, Thuy Le, Thomas S Harrison
Fungi are major contributors to the opportunistic infections that affect patients with HIV/AIDS. Systemic infections are mainly with Pneumocystis jirovecii (pneumocystosis), Cryptococcus neoformans (cryptococcosis), Histoplasma capsulatum (histoplasmosis), and Talaromyces (Penicillium) marneffei (talaromycosis). The incidence of systemic fungal infections has decreased in people with HIV in high-income countries because of the widespread availability of antiretroviral drugs and early testing for HIV. However, in many areas with high HIV prevalence, patients present to care with advanced HIV infection and with a low CD4 cell count or re-present with persistent low CD4 cell counts because of poor adherence, resistance to antiretroviral drugs, or both...
November 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28759746/serum-markers-as-an-aid-in-the-diagnosis-of-pulmonary-fungal-infections-in-aids-patients
#11
Ana Isabela Morsch Passos, Rachel Polo Dertkigil, Marcelo de Carvalho Ramos, Ariane Fidelis Busso-Lopes, Cibele Tararan, Erivan Olinda Ribeiro, Angélica Zaninelli Schreiber, Plinio Trabasso, Mariangela Ribeiro Resende, Maria Luiza Moretti
INTRODUCTION: The etiology of pulmonary infections in HIV patients is determined by several variables including geographic region and availability of antiretroviral therapy. MATERIALS AND METHODS: A cross-sectional prospective study was conducted from 2012 to 2016 to evaluate the occurrence of pulmonary fungal infection in HIV-patients hospitalized due to pulmonary infections. Patients' serums were tested for (1-3)-β-D-Glugan, galactomannan, and lactate dehydrogenase...
November 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28568970/the-changing-trends-and-profile-of-pneumocystosis-mortality-in-the-united-states-1999-2014
#12
Ranjana N Wickramasekaran, Mirna Ponce Jewell, Frank Sorvillo, Tony Kuo
Pneumocystosis (PCP) mortality in the U.S. has received less attention in recent years. This study describes recent trends in mortality and the estimated burden of PCP in the U.S., using the national multiple cause of death data during 1999-2014. PCP mortality rates were calculated for age, sex, race and year. Demographic differences were presented for decedents with and without a human immunodeficiency virus (HIV) co-diagnosis. Matched odds ratios (MOR) were generated to describe associations between non-HIV conditions and PCP mortality...
September 2017: Mycoses
https://www.readbyqxmd.com/read/28548623/pneumocystis-carinii-infection-with-severe-pneumomediastinum-and-lymph-node-involvement-in-a-whippet-mixed-breed-dog
#13
Christiane Weissenbacher-Lang, Andrea Fuchs-Baumgartinger, Andrea Klang, Sibylle Kneissl, Armin Pirker, Sarina Shibly, Stephanie von Ritgen, Herbert Weissenböck, Frank Künzel
A 3.5-y-old Whippet mixed-breed dog was presented with a history of respiratory distress, exercise intolerance, and generalized demodicosis. Hematologic alterations included marked leukocytosis and neutrophilia. Radiographic examination showed a diffuse interstitial and mild peripheral alveolar lung pattern and pneumomediastinum. Because the cytologic examination of the bronchoalveolar aspirate was not diagnostic and a persistent perforation of the upper respiratory tract could not be ruled out, the dog was submitted to thoracoscopy, and subsequently the left cranial lung lobe as well as mediastinal and sternal lymph nodes were resected...
September 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28005039/-intrauterine-pneumocystis-infection
#14
E R Samitova, T N Ermak, I E Koltunov, A N Kislyakov, N V Karazhas, T N Rybalkina, M Yu Kornienko
Pneumocystosis is well known as an opportunistic infection that is presently most frequently registered in patients with HIV infection and in those with other immunodeficiency states. Earlier, after the Second World War, Pneumocystis pneumonia was most commonly detected in debilitated and premature children; nosocomial outbreaks of pneumocystosis were studied in detail in the 1960s and 1970s. The pathogen is transmitted through the air, but a number of references indicate that it can be transmitted through the placenta...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27890947/profile-of-pneumocystis-infection-in-a-tertiary-care-institute-in-north-india
#15
Ravinder Kaur, Pragyan Swagatika Panda, Richa Dewan
CONTEXT: Pneumocystis jirovecii pneumonia (PcP) is still remains a common opportunistic disease in human immunodeficiency virus (HIV) infected individuals. Study on PcP in developing countries are scarce. AIMS: To study the occurrence of P. jirovecii infection in clinically suspected individuals in a tertiary care institute. SETTINGS AND DESIGN: Retrospective study conducted in a tertiary care hospital. MATERIALS AND METHODS: Two years data regarding respiratory sample analysis, HIV status, and cluster of differentiation 4 (CD4) cell count of clinically suspected pneumocystis infection patients with known/unknown HIV status were analyzed...
July 2016: Indian journal of sexually transmitted diseases and AIDS
https://www.readbyqxmd.com/read/27890172/opportunistic-infections-in-biological-therapy-risk-and-prevention
#16
REVIEW
Paul A Bryant, John W Baddley
Patients being treated with biological therapies are at increased risk for serious infections, including opportunistic infections. Although more is known about opportunistic infection risk with older biologics, such as antitumor necrosis factor drugs, there is less knowledge of opportunistic infection risk with newer biological therapies. The incidence of certain opportunistic infections (tuberculosis, herpes zoster, pneumocystosis) has been rigorously evaluated in large observational studies. However, data are more limited for other infections (histoplasmosis, nontuberculous mycobacteria)...
February 2017: Rheumatic Diseases Clinics of North America
https://www.readbyqxmd.com/read/27890037/grouped-cases-of-pulmonary-pneumocystosis-after-solid-organ-transplantation-advantages-of-coordination-by-an-infectious-diseases-unit-for-overall-management-and-epidemiological-monitoring
#17
Claire Wintenberger, Daniele Maubon, Elena Charpentier, John Rendu, Patricia Pavese, Caroline Augier, Paolo Malvezzi, Boubou Camara, Marie-Reine Mallaret, Laurence Bouillet, Olivier Epaulard
OBJECTIVE To determine the origin of grouped cases of Pneumocystis pneumonia in solid-organ transplant recipients at our institution. DESIGN A case series with clinical examinations, genotyping, and an epidemiological survey. SETTING A university hospital in France. PATIENTS We report 12 solid-organ transplant recipients with successive cases of Pneumocystis pneumonia that occurred over 3 years; 10 of these cases occurred in a single year. METHODS We used molecular typing of P. jirovecii strains by multilocus sequence typing and clinical epidemiological survey to determine potential dates and places of transmission...
February 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27824115/serological-diagnosis-of-pneumocystosis-production-of-a-synthetic-recombinant-antigen-for-immunodetection-of-pneumocystis-jirovecii
#18
A L Tomás, F Cardoso, F Esteves, O Matos
Diagnosis of Pneumocystis pneumonia (PcP) relies on the detection of P. jirovecii in respiratory specimens obtained by invasive techniques. Thus, the development of a serological test is urgently needed as it will allow the diagnosis of PcP using blood, an inexpensive and non-invasive specimen. This study aims to combine the production of a multi-epitope synthetic recombinant antigen (RSA) and an ELISA test for detection of anti-P. jirovecii antibodies, in order to develop a new approach for PcP diagnosis. The RSA was selected and designed based on the study of the immunogenicity of the carboxyl-terminal domain of the major surface glycoprotein...
November 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27613208/mortality-from-fungal-diseases-in-the-us-air-force-from-1970-to-2013
#19
Richard K Kugblenu, Will K Reeves
We review a unique set of documents, death certificates, catalogued in the US Air Force Mortality Registry, which tracks deaths for current and retired Air Force service members. We screened the records for all deaths caused by fungal diseases between 1970 and 2013. There were 216 deaths caused by a variety of diseases such as aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, mucormycosis, pneumocystosis, sporotrichosis, and zygomycosis. The single most common identified cause of death was opportunistic candidiasis...
October 2016: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/27476330/cytotoxic-mutagenicity-and-genotoxicity-effects-of-guanylhydrazone-derivatives
#20
Valéria Rodrigues Pinhatti, Juliana da Silva, Tales Leandro Costa Martins, Dinara Jaqueline Moura, Renato Moreira Rosa, Izabel Villela, Cheila Denise Ottonelli Stopiglia, Selma da Silva Santos, Maria Lúcia Scroferneker, Carlos Renato Machado, Jenifer Saffi, João Antonio Pêgas Henriques
Several studies have reported that guanylhydrazones display a variety of desirable biological properties, such as antihypertensive, antibacterial, and antimalarial behaviour. They furthermore promote anti-pneumocystosis and anti-trypanosomiasis, exhibit antitumor activity, and show significant cytotoxicity against cancer cell lines. In this work, we have evaluated the cytotoxicity, mutagenicity, and genotoxicity of two guanylhydrazones derivatives, (E)-2-[(2,3-dimethoxyphenyl) methylene] hydrazine carboxymidamide hydrochloride (2,3-DMeB) and (E)-2-[(3,4-dimethoxyphenyl) methylene] hydrazine carboxymidamide hydrochloride (3,4-DMeB), in different biological models...
August 2016: Mutation Research. Genetic Toxicology and Environmental Mutagenesis
keyword
keyword
167948
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"