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Ventricular fibrillation

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https://www.readbyqxmd.com/read/29908369/repolarization-heterogeneity-in-patients-with-cardiac-resynchronization-therapy-and-its-relation-to-ventricular-tachyarrhythmias
#1
Marta Cvijić, Bor Antolič, Luka Klemen, Igor Zupan
BACKGROUND: s: Cardiac resynchronization therapy (CRT) has shown to induce left ventricular reverse remodelling, but little is known about its influence on ventricular repolarization. OBJECTIVE: The aim of our study was to evaluate changes of ventricular repolarization of native conduction after CRT and its relation to ventricular tachycardia (VT) and ventricular fibrillation (VF) during long-term follow-up. METHODS: We prospectively included 64 patients with heart failure treated with CRT...
June 13, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29907995/fifteen-years-of-life-losartan-intervention-for-endpoint-reduction-in-hypertension-lessons-learned-for-losartan-an-old-dog-playing-good-tricks
#2
REVIEW
Niki Katsiki, Konstantinos Tsioufis, Dilek Ural, Massimo Volpe
There is an unmet need to prevent cardiovascular disease and chronic kidney disease development and progression worldwide. Losartan, the first angiotensin receptor blocker, was shown to exert significant cardioprotective and renoprotective effects in the LIFE (Losartan Intervention for Endpoint Reduction in Hypertension) and RENAAL (Reduction of Endpoints in NIDDM With the Angiotensin II Antagonist Losartan) trials. Losartan significantly prevented stroke and decreased serum uric acid levels and the rates of new-onset diabetes mellitus and atrial fibrillation...
June 15, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29907152/the-effect-of-myocardial-action-potential-duration-on-cardiac-pumping-efficacy-a-computational-study
#3
Da Un Jeong, Ki Moo Lim
BACKGROUND AND AIMS: Although studies on the relation between arrhythmias and the action potential duration (APD) have been carried out, most of them are based only on electrophysiological factors of the heart and lack experiments that consider cardiac mechanical and electromechanical characteristics. Therefore, we conducted this study to clarify the relevance of the shortening of APD of a cell in relation to the mechanical contraction activity of the heart and the associated risk of arrhythmia...
June 15, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29905788/extended-use-of-the-wearable-cardioverter-defibrillator-in-patients-at-risk-for-sudden-cardiac-death
#4
Valentina Kutyifa, Katherine Vermilye, Usama A Daimee, Scott McNitt, Helmut Klein, Arthur J Moss
Aims: Data on outcomes in patients using the wearable cardioverter-defibrillator (WCD) > 90 days are limited. We aimed to analyse the clinical course of patients with WCD use ≤90 days vs. WCD use >90 days. Methods and results: We assessed arrhythmia events during WCD use, and ejection fraction (EF) improvement/implantable cardioverter-defibrillator (ICD) implantation at the end of WCD use in patients with WCD use ≤90 days vs. WCD use >90 days enrolled in the WEARIT-II registry, further assessed by disease aetiology (ischaemic vs...
June 14, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29905371/a-rare-cause-of-ventricular-fibrillation-after-atrioventricular-node-ablation-what-is-the-mechanism
#5
Predrag Stojadinović, Petr Peichl, Dan Wichterle, Josef Kautzner
No abstract text is available yet for this article.
2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29904445/malignant-ventricular-arrhythmias-resulting-from-drug-induced-qtc-prolongation-a-retrospective-study
#6
Renato De Vecchis, Carmelina Ariano, Giuseppina Di Biase, Michel Noutsias
Background: Several drug classes (antiarrhythmics, antimicrobials, antidepressants, phenothiazines, opiates, prokinetics of digestive tract, etc.) have been related to ventricular hyperkinetic arrhythmias such as torsade de pointes (TdP). TdPs are usually heralded by an abnormal prolongation of heart rate-corrected QT interval on the electrocardiogram, so-called drug-induced long heart rate-corrected QT (diLQTc). We don't know to what extent the drug-induced QTc prolongation is able to predict malignant arrhythmias...
July 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29904302/acute-heart-failure-related-to-a-large-left-atrial-myxoma
#7
Giovanni A Chiariello, Piergiorgio Bruno, Christian Colizzi, Natalia Pavone, Marialisa Nesta, Federico Cammertoni, Andrea Mazza, Alfredo Posteraro, Gianluigi Perri, Massimo Massetti
An association between atrial myxoma and left ventricular failure is rarely described, is not completely understood, and may have multiple etiologies. We present a 49-year-old man with no history of cardiovascular disease who was admitted to our hospital with pulmonary edema. He was in atrial fibrillation with rapid ventricular response. Echocardiography showed a 10.5-cm left atrial myxoma, which had been asymptomatic until the onset of congestive heart failure in the presence of severe left ventricular systolic dysfunction...
July 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29904301/flecainide-toxicity-in-renal-failure
#8
Rogin Subedi, Ryan K Dean, Arbind Chaudhary, Tamas Szombathy
Flecainide, a class Ic antiarrhythmic, is used for the prevention of paroxysmal supraventricular tachycardia, paroxysmal atrial fibrillation/flutter, and sustained ventricular tachycardia. Flecainide is primarily metabolized by the liver and to a lesser extent (30%) is excreted unchanged in the kidney. We present a case of flecainide toxicity in the setting of renal impairment that was successfully treated with intravenous sodium bicarbonate.
July 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29899365/greater-nighttime-blood-pressure-variability-is-associated-with-left-atrial-enlargement-in-atrial-fibrillation-patients-with-preserved-ejection-fraction
#9
Naoki Norioka, Shinichi Iwata, Asahiro Ito, Soichiro Tamura, Yu Kawai, Shinichi Nonin, Sera Ishikawa, Atsushi Doi, Akihisa Hanatani, Minoru Yoshiyama
Left atrial enlargement is an independent risk factor for ischemic stroke in patients with atrial fibrillation. Little is known regarding the association between nighttime blood pressure variability and left atrial enlargement in patients with atrial fibrillation and preserved ejection fraction. The study population consisted of 140 consecutive patients with atrial fibrillation (mean age 64 ± 10 years) with preserved ejection fraction (≥50%). Nighttime blood pressure was measured at hourly intervals, using a home blood pressure monitoring device...
June 13, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29898675/in-hospital-major-arrhythmias-arrhythmic-death-and-resuscitation-after-successful-primary-percutaneous-intervention-for-acute-transmural-infarction-a-retrospective-single-centre-cohort-study
#10
Marco Albanese, Korhan Alpaslan, Taoufik Ouarrak, Peter Merguet, Steffen Schneider, Wolfgang Schöls
BACKGROUND: Transmural acute myocardial infarction (AMI) is associated with a high risk for ventricular arrhythmia before, during and after treatment. Consequently, it is recommended that patients diagnosed with transmural AMI be monitored in a cardiac care unit (CCU) so life-threatening arrhythmias can be treated promptly. We examined the incidence and timing of in-hospital malignant ventricular arrhythmias, sudden cardiac or arrhythmic death (SCD/AD) and resuscitation requirements in patients with transmural AMI recovering from percutaneous coronary intervention (PCI) undertaken within 12 h of symptom onset and without antecedent thrombolysis...
June 14, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29898017/cohort-of-patients-referred-for-brugada-syndrome-investigation-in-an-electrophysiology-service-19-year-registry
#11
Stefan Warpechowski Neto, Tiago Luiz Luz Leiria, Laura Lessa Gaudie Ley, Antonio Lessa Gaudie Ley, Luiza Zwan Dutra, Leonardo Martins Pires, Marcelo Lapa Kruse, Gustavo Glotz de Lima
BACKGROUND: Brugada syndrome (SBr) is an arrhythmic condition characterized by ST-T segment abnormalities in the right precordial leads associated with a high risk of ventricular arrhythmias and sudden death. Local data regarding the clinical characteristics of patients with a typical electrocardiographic (ECG) pattern undergoing electrophysiological study are scarce. OBJECTIVE: To evaluate patients with an ECG pattern suggestive of SBr referred for electrophysiological evaluation in a specialized center...
June 11, 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29897909/electrocardiographic-abnormalities-in-chagas-disease-in-the-general-population-a-systematic-review-and-meta-analysis
#12
Lyda Z Rojas, Marija Glisic, Laura Pletsch-Borba, Luis E Echeverría, Wichor M Bramer, Arjola Bano, Najada Stringa, Asija Zaciragic, Bledar Kraja, Eralda Asllanaj, Rajiv Chowdhury, Carlos A Morillo, Oscar L Rueda-Ochoa, Oscar H Franco, Taulant Muka
BACKGROUND: Chagas disease (CD) is a major public health concern in Latin America and a potentially serious emerging threat in non-endemic countries. Although the association between CD and cardiac abnormalities is widely reported, study design diversity, sample size and quality challenge the information, calling for its update and synthesis, which would be very useful and relevant for physicians in non-endemic countries where health care implications of CD are real and neglected. We performed to systematically review and meta-analyze population-based studies that compared prevalence of overall and specific ECG abnormalities between CD and non-CD participants in the general population...
June 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29897343/a-comparison-of-entropy-approaches-for-af-discrimination
#13
Chengyu Liu, Julien Oster, Erik Reinertsen, Qiao Li, Lina Zhao, Shamim Nemati, Gari D Clifford
This study focused on the comparison of single entropy measures for the ventricular response analysis-based AF detection. To enhance the performance of entropy-based AF detectors, we developed a normalized fuzzy entropy, <i>H</i><sup>θ</sup><sub>N</sub> , a novel metric that: 1) uses a fuzzy function to determine vector similarity, 2) replaces probability estimation with density estimation for entropy approximation, 3) utilizes a flexible distance threshold parameter, and 4) adjusts for heart rate by subtracting the natural log value of the mean RR interval...
June 13, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29893985/-management-of-hypertrophic-cardiomyopathy-the-most-common-inherited-heart-disease
#14
Peter Magnusson, Fredrik Gadler, Stellan Mörner
Hypertrophic cardiomyopathy is the most common cardiogenetic disease affecting 1/500-1/1 000 individuals. Dyspnea is common but chest pain, dizziness or fainting may also cause considerable limitation for the patient. The diagnosis can be suspected from ECG. Echocardiography confirms hypertrophy of at least 15 mm, usually in the septum. If the obstruction of the outflow tract is severe, myectomy or alcohol ablation can relieve symptoms. Genetic evaluation of family members is advisable. To reduce symptoms, betablockers are used; verapamil or disopyramide are alternatives...
June 11, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29893820/ajmaline-induced-epsilon-wave-as-a-potential-interim-risk-factor-between-the-spontaneous-and-drug-induced-type-1-brugada-electrogram-authors-reply
#15
Masahiko Takagi, Yukio Sekiguchi, Yasuhiro Yokoyama, Naohiko Aihara, Masayasu Hiraoka, Kazutaka Aonuma
No abstract text is available yet for this article.
June 8, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29893508/effect-of-defibrillation-threshold-testing-on-effectiveness-of-the-subcutaneous-implantable-cardioverter-defibrillator
#16
Lakshmi Peddareddy, Faisal M Merchant, Angel R Leon, Paige Smith, Akshar Patel, Mikhael F El-Chami
BACKGROUND: Defibrillation threshold (DFT) testing is recommended with the subcutaneous ICD (SICD). OBJECTIVE: To describe first shock efficacy for appropriate SICD therapies stratified by the presence of implant DFT testing. METHODS: We reviewed all patients receiving SICDs at our institution and stratified them based on whether implant DFT testing was performed. Appropriate shocks were reviewed to see if ventricular tachycardia/ventricular fibrillation (VT/VF) terminated with a single shock...
June 12, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29892706/clinical-and-electrocardiographic-characteristics-for-prediction-of-new-onset-atrial-fibrillation-in-asymptomatic-patients-with-atrial-premature-complexes
#17
Sung Il Im, Dong Hyun Park, Bong Joon Kim, Kyoung Im Cho, Hyun Su Kim, Jung Ho Heo
Backgrounds: Identification of precursors of atrial fibrillation (AF) may lead to early detection and prevent associated morbidity and mortality. Atrial premature complexes (APCs) are commonly seen in healthy subjects. However, there was limited data about the clinical and electrocardiographic (ECG) characteristics for prediction of new-onset AF in asymptomatic patients with APCs in the long-term follow up. Methods: The Kosin University (No. 2014-02-04) 24-h holter monitoring, echocardiography, ECG database were reviewed from 2008 to 2016 to identify new- onset AF in patients with APCs...
June 2018: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29892226/blood-shift-during-cough-negligible-or-significant
#18
Antonella LoMauro, Andrea Aliverti
Rationale: It was reported how forceful rhythmic coughing can provide effective blood flow during ventricular fibrillation without direct chest compression. This mechanism of cough-assisted cardiopulmonary resuscitation constitutes a form of "cardiac massage" secondary to the intrathoracic and intra-abdominal pressure changes during cough. We have previously shown that significant blood shifts (BSs) occurs from the thorax to the extremities during expulsive maneuvers and that abdominal pressure controls the outflow of blood from the splanchnic vasculature...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29891045/biventricular-thrombi-in-a-patient-with-heart-failure-with-severely-reduced-ejection-fraction-and-heterozygous-prothrombin-20210g-a-and-homozygous-methylenetetrahydrofolate-reductase-677c-t-mutations
#19
REVIEW
Htoo Kyaw, Fatima Shaik, Won J Park, Deepika Misra
Thrombus in the heart is known to be one of the many sequelae of anterior wall myocardial infarction, atrial fibrillation and coagulation disorders. However, biventricular thrombi are relatively rarely found, even in conditions with a high possibility of thrombus formation. We report the case of a 75-year-old-woman with newly diagnosed systolic heart failure secondary to a nonischemic cardiomyopathy, who was found to have large biventricular thrombi. Further coagulopathy work-up revealed that she was heterozygous for the prothrombin 20210G/A and homozygous for the methylenetetrahydrofolate reductase (MTHFR) 677C/T mutations...
June 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29887578/poor-rhythm-outcome-of-catheter-ablation-for-early-onset-atrial-fibrillation-in-women-mechanistic-insight
#20
Hee Tae Yu, Pil-Sung Yang, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
BACKGROUND: Catheter ablation is a good treatment option for atrial fibrillation (AF) in young symptomatic patients. However, there is little information on the efficacy of catheter ablation of early-onset AF between sexes.Methods and Results:This study included 1,060 patients under the age 60 years old (837 men, 49.8±7.7 years old, 70.8% paroxysmal AF) who underwent catheter ablation for AF. Sex differences in clinical presentation and ablation outcomes were compared with and without propensity score-matching...
June 8, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
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