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https://www.readbyqxmd.com/read/29240666/induction-of-inflammation-in-vivo-by-electrocardiogram-sensor-operation-using-wireless-power-transmission
#1
Jin-Chul Heo, Beomjoon Kim, Yoon-Nyun Kim, Dae-Kwang Kim, Jong-Ha Lee
Prolonged monitoring by cardiac electrocardiogram (ECG) sensors is useful for patients with emergency heart conditions. However, implant monitoring systems are limited by lack of tissue biocompatibility. Here, we developed an implantable ECG sensor for real-time monitoring of ventricular fibrillation and evaluated its biocompatibility using an animal model. The implantable sensor comprised transplant sensors with two electrodes, a wireless power transmission system, and a monitoring system. The sensor was inserted into the subcutaneous tissue of the abdominal area and operated for 1 h/day for 5 days using a wireless power system...
December 14, 2017: Sensors
https://www.readbyqxmd.com/read/29238755/spatiotemporal-progression-of-early-human-ventricular-fibrillation
#2
David Vidmar, David E Krummen, Justin Hayase, Sanjiv M Narayan, Gordon Ho, Wouter-Jan Rappel
Objectives: The objective of this study was to evaluate the spatio-temporal organization and progression of human ventricular fibrillation (VF) in the left (LV) and right (RV) ventricles. Background: Studies suggest that localized sources contribute to VF maintenance, but the evolution of VF episodes has not been quantified. Methods: Synchrony between electrograms recorded from 25 patients with induced VF is computed and used to define the Asynchronous Index (ASI), indicating regions which are out-of-step with surrounding tissue...
December 11, 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29237675/gene-based-risk-stratification-for-cardiac-disorders-in-lmna-mutation-carriers
#3
Suguru Nishiuchi, Takeru Makiyama, Takeshi Aiba, Kenzaburo Nakajima, Sayako Hirose, Hirohiko Kohjitani, Yuta Yamamoto, Takeshi Harita, Mamoru Hayano, Yimin Wuriyanghai, Jiarong Chen, Kenichi Sasaki, Nobue Yagihara, Taisuke Ishikawa, Kenji Onoue, Nobuyuki Murakoshi, Ichiro Watanabe, Kimie Ohkubo, Hiroshi Watanabe, Seiko Ohno, Takahiro Doi, Satoshi Shizuta, Tohru Minamino, Yoshihiko Saito, Yasushi Oginosawa, Akihiko Nogami, Kazutaka Aonuma, Kengo Kusano, Naomasa Makita, Wataru Shimizu, Minoru Horie, Takeshi Kimura
BACKGROUND: Mutations in LMNA (lamin A/C), which encodes lamin A and C, typically cause age-dependent cardiac phenotypes, including dilated cardiomyopathy, cardiac conduction disturbance, atrial fibrillation, and malignant ventricular arrhythmias. Although the type of LMNA mutations have been reported to be associated with susceptibility to malignant ventricular arrhythmias, the gene-based risk stratification for cardiac complications remains unexplored. METHODS AND RESULTS: The multicenter cohort included 77 LMNA mutation carriers from 45 families; cardiac disorders were retrospectively analyzed...
December 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/29237655/evaluation-using-cardiac-insertable-devices-and-telephone-in-hypertrophic-cardiomyopathy-elucidate-hcm-rationale-and-design-a-prospective-observational-study-on-incidence-of-arrhythmias-in-sweden
#4
Peter Magnusson, Stellan Mörner
INTRODUCTION: Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease associated with sudden cardiac death (SCD) mainly due to ventricular tachycardia (VT) or fibrillation even though life-threatening bradycardia occurs. Risk stratification takes several variables into consideration including non-sustained VT (NSVT). An implantable cardioverter defibrillator effectively prevents SCD.Atrial fibrillation (AF) is common among patients with HCM and warrants anticoagulation even without conventional risk factors according to European guidelines...
December 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29237608/significance-of-inducible-nonsustained-ventricular-tachycardias-after-catheter-ablation-for-ventricular-tachycardia-in-ischemic-cardiomyopathy
#5
Akira Fujii, Koichi Nagashima, Saurabh Kumar, Shinichi Tanigawa, Samuel H Baldinger, Gregory F Michaud, Roy M John, Bruce A Koplan, Michifumi Tokuda, Keiichi Inada, Usha B Tedrow, William G Stevenson
BACKGROUND: Noninducibility of sustained monomorphic ventricular tachycardia (SMVT) postablation does not insure absence of later recurrence in patients with ischemic cardiomyopathy. This study aims to determine the relation between inducible nonsustained VT postablation and VT recurrences. METHODS AND RESULTS: One hundred sixty-five consecutive patients (156 male; age 68±9 years) underwent ablation for SMVT because of ischemic cardiomyopathy; 44 patients who did not have induction testing or in whom only ventricular fibrillation was induced after ablation were excluded...
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29237243/exercise-related-severe-cardiac-events
#6
Lourdes Vicent, Albert Ariza-Solé, José Ramón González-Juanatey, Aitor Uribarri, José Ortiz, Esteban López de Sá, Jordi Sans-Roselló, Carlos Tomás Querol, Pau Codina, Iago Sousa-Casasnovas, Manuel Martínez-Sellés
BACKGROUND: Physical activity has benefits on health. However, there is a small risk of effort-related adverse events. The aim of this study is to describe exercise-related severe cardiovascular events and to relate them with the type of sport performed. METHODS: Ten-year retrospective study in 8 Spanish cardiac intensive care units. Adverse cardiac events were defined as acute myocardial infarction, cardiac arrest, or syncope related to physical activity. RESULTS: From 117 patients included, 109 were male (93...
December 13, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29235737/long-term-survival-of-discharged-patients-admitted-to-intensive-coronary-care-unit-after-out-of-hospital-cardiac-arrest
#7
Dante Antonelli, Ofir Koren, Menachem Nahir, Ehud Rozner, Nahum A Freedberg, Yoav Turgeman
BACKGROUND: Survival of patients who were discharged from the hospital following out-of-hospital cardiac arrest (OHCA) has not been well defined. OBJECTIVES: To verify predictor variables for prognosis of patients following OHCA who survived hospitalization. METHODS: We retrospectively reviewed clinical, demographic, and outcome data of consecutive patients who were hospitalized from January 1, 2009, through December 31, 2014, into the intensive coronary care unit (ICCU) after aborted OHCA and discharged alive...
December 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29233088/left-atrial-enlargement-and-clinical-considerations-in-patients-with-or-without-a-residual-interatrial-shunt-after-closure-of-the-left-atrial-appendage-with-the-watchman%C3%A2-device
#8
Blerim Luani, Thomas Groscheck, Conrad Genz, Ivan Tanev, Thomas Rauwolf, Joerg Herold, Senad Medunjanin, Alexander Schmeisser, Rüdiger C Braun-Dullaeus
BACKGROUND: Interventional closure of the left atrial appendage (LAA) in patients with non-valvular atrial fibrillation, high thromboembolic and bleeding risk or bleeding history is an alternative therapeutic strategy to oral anticoagulation. It is not known if the exclusion of the LAA from the blood circulation affects the left atrial volume (LAV) and consequently its prognostic value or the circulatory performance of the heart in humans. METHODS: We aimed to prospectively assess potential changes in baseline LAV, left ventricular ejection fraction (LVEF), NT-proBNP-level and the covered distance in the 6-min walk-test 6 weeks and 6 months after LAA closure with the WATCHMAN™ device...
December 12, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29229649/isolated-tricuspid-regurgitation-outcomes-and-therapeutic-interventions
#9
REVIEW
Erin A Fender, Chad J Zack, Rick A Nishimura
Isolated tricuspid regurgitation (TR) can be caused by primary valvular abnormalities such as flail leaflet or secondary annular dilation as is seen in atrial fibrillation, pulmonary hypertension and left heart disease. There is an increasing recognition of a subgroup of patients with isolated TR in the absence of other associated cardiac abnormalities. Left untreated isolated TR significantly worsens survival. Stand-alone surgery for isolated TR is rarely performed due to an average operative mortality of 8%-10% and a paucity of data demonstrating improved survival...
December 11, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29228895/postcardiotomy-refractory-ventricular-fibrillation-rescue-using-veno-arterial-extracorporeal-membrane-oxygenation
#10
Ilya Soynov, Igor Kornilov, Alexey Zubritskiy, Dmitriy Ponomarev, Nataliya Nichay, Artem Gorbatykh, Alexey Voitov, Alexander Karaskov
We present a case of 7-hour ventricular fibrillation with successful use of veno-arterial extracorporeal membrane oxygenation as a bridge to recovery in a 30-year-old patient with grown-up congenital heart disease who underwent pulmonary valve replacement.
December 1, 2017: Perfusion
https://www.readbyqxmd.com/read/29226831/public-access-defibrillation-in-hong-kong-in-2017
#11
K L Fan, C T Lui, L P Leung
The concept of public access defibrillation was proposed more than 20 years ago. Since then, various programmes have been implemented in many major cities although not all have been successful. Fourteen years ago, the question of whether Hong Kong needed public access defibrillation was raised. This article aimed to answer this question based on the best available evidence. Over the years, the clinical effectiveness of public access defibrillation in out-of-hospital cardiac arrest has been proven. Nonetheless various studies have indicated that among others, cost-effectiveness, knowledge and attitudes of the public, and incidence of ventricular fibrillation are important factors that will affect the likelihood of success of such programmes...
December 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29225104/evaluation-of-qt-dispersion-and-t-peak-to-t-end-interval-in-patients-with-early-stage-sarcoidosis
#12
Hacı Ahmet Kasapkara, Ayşegül Şentürk, Emine Bilen, Hüseyin Ayhan, Bilge Duran Karaduman, Zeynep Şeyma Turinay, Murat Can Güney, Tahir Durmaz, Telat Keleş, Engin Bozkurt
INTRODUCTION AND AIM: Sarcoidosis increases inhomogeneity in ventricular repolarization due to the presence of sarcoid granuloma, which significantly correlates with ventricular fibrillation. Various studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (T-peak to T-end [Tpe] interval) may correspond to the transmural dispersion of repolarization and that increased Tpe interval and Tpe/QT ratio are associated with malignant ventricular arrhythmias...
December 7, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29223306/diagnostic-accuracy-of-multi-lead-ecgs-obtained-using-a-pocket-sized-bipolar-handheld-event-recorder
#13
Ani Nigolian, Nicolas Dayal, Haïg Nigolian, Carine Stettler, Haran Burri
BACKGROUND: Handheld ECG event recorders are useful for rhythm monitoring but only record a single lead, which may limit interpretation. We sought to investigate if a multi-lead ECG may be reconstituted using this device, and aimed to evaluate diagnostic accuracy. METHODS: A commercially-available handheld bipolar ECG event recorder was used to reconstruct a 9-lead ECG (leads I, II and III, V1-6). Tracings were analyzed independently by a cardiologist and a fellow...
November 21, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29221700/acute-and-long-term-results-after-contemporary-subcutaneous-implantable-cardioverter-defibrillator-implantation-a-single-center-experience
#14
Miguel A Arias, Marta Pachón, Finn Akerström, Alberto Puchol, Cristina Martín-Sierra, Luis Rodríguez-Padial
INTRODUCTION AND OBJECTIVES: The subcutaneous implantable cardioverter-defibrillator (S-ICD) has emerged as an alternative to the transvenous defibrillator. The incidence of complications is similar, with inappropriate shocks (IS) being more frequent than those occurring with contemporary programming of transvenous defibrillators. Several improvements have been implemented after the S-ICD was approved for use in Europe in 2009. This study reports the results of S-ICD use in a single center, whose experience began late, at the end of 2013...
December 5, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29221300/comparison-of-continuous-compression-with-regular-ventilations-versus-30-2-compressions-ventilations-strategy-during-mechanical-cardiopulmonary-resuscitation-in-a-porcine-model-of-cardiac-arrest
#15
Zhengfei Yang, Qingyu Liu, Guanghui Zheng, Zhifeng Liu, Longyuan Jiang, Qing Lin, Rui Chen, Wanchun Tang
Background: A compression-ventilation (C:V) ratio of 30:2 is recommended for adult cardiopulmonary resuscitation (CPR) by the current American Heart Association (AHA) guidelines. However, continuous chest compression (CCC) is an alternative strategy for CPR that minimizes interruption especially when an advanced airway exists. In this study, we investigated the effects of 30:2 mechanical CPR when compared with CCC in combination with regular ventilation in a porcine model. Methods: Sixteen male domestic pigs weighing 39±2 kg were utilized...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29220423/tpeak-tend-interval-during-therapeutic-hypothermia-can-predict-upcoming-ventricular-fibrillation-in-subjects-with-aborted-arrhythmic-sudden-cardiac-death-3-years-follow-up-results
#16
Namsik Yoon, Seo Hong, Aaron Glass, Sung Soo Kim, Min Chul Kim, Jae Yeong Cho, Ki Hong Lee, Doo Sun Sim, Hyun Ju Yoon, Kye Hun Kim, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Jeong, Jong Chun Park, Jeong Gwan Cho
Aims: Prolonged Tpeak-Tend interval has been shown to be markers of arrhythmogenesis in various cardiac disorders. However, its dynamicity is one of the obstacles to predict fatal ventricular arrhythmia. This study investigated whether Tpeak-Tend interval during therapeutic hypothermia (TH) is associated with ventricular fibrillation (VF) inducibility and clinical arrhythmia in subjects with aborted arrhythmic sudden cardiac death (SCD). Methods and results: The study group included 31 patients (24 males, age 39...
December 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29220422/atrioventricular-node-ablation-and-his-bundle-pacing
#17
Pugazhendhi Vijayaraman, Faiz A Subzposh, Angela Naperkowski
Aims: Atrioventricular node ablation (AVNA) and right ventricular pacing (RVP) are effective therapies for patients with atrial fibrillation (AF) and rapid ventricular rates. His bundle pacing (HBP) is a physiologic alternative to RVP. The aim of our study is to assess the feasibility and safety of HBP in patients undergoing AVNA and its effect on left ventricular (LV) function. Methods and results: Permanent HBP is the preferred form of ventricular pacing at our institute...
December 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29218016/synergistic-anti-arrhythmic-effects-in-human-atria-with-combined-use-of-sodium-blockers-and-acacetin
#18
Haibo Ni, Dominic G Whittaker, Wei Wang, Wayne R Giles, Sanjiv M Narayan, Henggui Zhang
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Developing effective and safe anti-AF drugs remains an unmet challenge. Simultaneous block of both atrial-specific ultra-rapid delayed rectifier potassium (K+) current (IKur) and the Na+ current (INa) has been hypothesized to be anti-AF, without inducing significant QT prolongation and ventricular side effects. However, the antiarrhythmic advantage of simultaneously blocking these two channels vs. individual block in the setting of AF-induced electrical remodeling remains to be documented...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29217152/advanced-cardiopulmonary-resuscitation-cpr-in-the-catheterization-laboratory-consensus-document-of-the-working-groups-of-1-cardiopulmonary-resuscitation-acute-cardiac-care-and-2-hemodynamic-and-interventional-cardiology-hellenic-cardiological-society
#19
George Latsios, George Mpompotis, Kostas Tsioufis, Kostas Toutouzas, Emmanouil Skalidis, Andreas Synetos, Dimosthenis Avramidis, Dimitris Tousoulis
The incidence of Cardiac (Cardio-Pulmonary) Arrest (CA) in the Catheterization Laboratory is not common. However, not only does it happen occasionally but its frequency tends to increase due to the increase in the overall number and complexity of interventions performed by interventional cardiologists. Therefore, certified knowledge and application of the ALS (Advanced Life Support) protocols by trained Catheterization Laboratory staff is imperative in many countries, by local Hospital standards and also by Law...
December 4, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29216948/-tea-polyphenols-down-regulate-jnk-phosphorylation-to-inhibit-neuron-apoptosis-in-rats-with-cardiac-arrest
#20
Yumei Liu, Thi Phuong Anh Nguyen, Menghua Chen, Lu Xie
OBJECTIVE: To study the effect of tea polyphenols (TP) on c-Jun N-terminal kinase 1/2 (JNK1/2) phosphorylation and cell apoptosis in brain tissues in rats with cardiac arrest (CA) following cardiopulmonary resuscitation (CPR). METHODS: Healthy male Sprague-Dawley (SD) rats were randomly divided into sham group (n = 6), CA group (n = 12), and TP group (n = 12). The rats in CA and TP groups were induced ventricular fibrillation (VF) via esophagus stimulation with alternating current...
December 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
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