Shruti K Gohil, Edward Septimus, Ken Kleinman, Neha Varma, Taliser R Avery, Lauren Heim, Risa Rahm, William S Cooper, Mandelin Cooper, Laura E McLean, Naoise G Nickolay, Robert A Weinstein, L Hayley Burgess, Micaela H Coady, Edward Rosen, Selsebil Sljivo, Kenneth E Sands, Julia Moody, Justin Vigeant, Syma Rashid, Rebecca F Gilbert, Kim N Smith, Brandon Carver, Russell E Poland, Jason Hickok, S G Sturdevant, Michael S Calderwood, Anastasiia Weiland, David W Kubiak, Sujan Reddy, Melinda M Neuhauser, Arjun Srinivasan, John A Jernigan, Mary K Hayden, Abinav Gowda, Katyuska Eibensteiner, Robert Wolf, Jonathan B Perlin, Richard Platt, Susan S Huang
IMPORTANCE: Urinary tract infection (UTI) is the second most common infection leading to hospitalization and is often associated with gram-negative multidrug-resistant organisms (MDROs). Clinicians overuse extended-spectrum antibiotics although most patients are at low risk for MDRO infection. Safe strategies to limit overuse of empiric antibiotics are needed. OBJECTIVE: To evaluate whether computerized provider order entry (CPOE) prompts providing patient- and pathogen-specific MDRO risk estimates could reduce use of empiric extended-spectrum antibiotics for treatment of UTI...
April 19, 2024: JAMA