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Pipeline embolic device

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https://www.readbyqxmd.com/read/30298832/flow-diverter-therapy-using-a-pipeline-embolization-device-for-100-unruptured-large-and-giant-internal-carotid-artery-aneurysms-in-a-single-center-in-a-japanese-population
#1
Hidenori Oishi, Kosuke Teranishi, Kenji Yatomi, Takashi Fujii, Munetaka Yamamoto, Hajime Arai
Flow diverters (FDs) have been developed for intracranial aneurysms difficult to treat with conventional endovascular therapy and surgical clipping. We reviewed 94 patients with 100 large or giant unruptured internal carotid artery (ICA) aneurysms treated with Pipeline embolization device (PED) embolization from December 2012 to June 2017 at Juntendo University Hospital. The patients' mean age was 63.4 years (range, 19-88), and there were 90 women 89.4%. Aneurysm locations were: C4 (45), C3 (4), and C2 (51) in ICA segments...
October 6, 2018: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/30273722/moderate-sedation-for-pipeline-embolization-of-posterior-circulation-disease-technical-note-from-a-single-center
#2
Vijay M Ravindra, Julius Griauzde, Jonathan P Scoville, Craig J Kilburg, D Andrew Wilkinson, Clint Christensen, William T Couldwell, Philipp Taussky
OBJECTIVE: Flow diversion has been an important addition to endovascular neurosurgery, but its use in the posterior circulation remains controversial. Our goal is to describe the safety and efficacy of moderate sedation during flow diversion for posterior circulation lesions (aneurysms or dissecting pseudoaneurysms). METHODS: The authors retrospectively reviewed the medical records of all patients who underwent placement of a Pipeline embolization device for a posterior circulation lesion from August 2012 through November 2017...
September 28, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30272561/endovascular-treatment-of-true-renal-artery-aneurysms-a-single-center-experience
#3
Gonca Eldem, Erhan Erdoğan, Bora Peynircioğlu, Anıl Arat, Ferhun Balkancı
PURPOSE: We aimed to report a single center's experience on endovascular treatment of true renal artery aneurysms (TRAAs), including treatment techniques and outcomes. METHODS: This retrospective study was designed to evaluate the treatment and follow-up of TRAAs treated by a variety of endovascular interventional techniques over a period of 6 years. Six patients with nine TRAAs were identified; seven of the TRAAs were treated using different combinations of coil embolization and flow diverter stents...
September 28, 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/30262655/treatment-of-intracranial-aneurysms-using-the-pipeline-flex-embolization-device-with-shield-technology-angiographic-and-safety-outcomes-at-1-year-follow-up
#4
Mario Martínez-Galdámez, Saleh M Lamin, Konstantinos G Lagios, Thomas Liebig, Elisa F Ciceri, Rene Chapot, Luc Stockx, Swarupsinh Chavda, Christoph Kabbasch, Giuseppe Faragò, Hannes Nordmeyer, Thierry Boulanger, Mariangela Piano, Edoardo P Boccardi
PURPOSE: The Pipeline Embolization Device (PED) is a routine first-line treatment option for intracranial aneurysms (IAs). The Pipeline Flex Embolization Device with Shield Technology (Pipeline Shield) is an updated version of the PED which has been modified to include a surface phosphorylcholine biocompatible polymer. Its early technical success and safety have been reported previously. Here, we assessed the long-term safety and efficacy of the Pipeline Shield for the treatment of IAs...
September 27, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/30196685/first-human-evaluation-of-endothelial-healing-after-a-pipeline-flex-embolization-device-with-shield-technology-implanted-in-posterior-circulation-using-optical-coherence-tomography
#5
Boris Pabón Guerrero, Carlos Díaz Pacheco, Ahmed Saied, Krishna Joshi, Claudio Rodríguez, Mario Martínez-Galdámez, Demetrius K Lopes
A 64-year-old female presented with an incidentally-discovered right posterior inferior cerebral artery (PICA) aneurysm, initially treated in 2015 by simple coiling. Follow-up demonstrated significant coil compaction that required retreatment. Retreatment was done uneventfully using a Pipeline embolization device (PED) shield deployed starting from the basilar artery and ending at the V4 segment of the vertebral artery. Eight-weeks post-deployment, a follow-up digital subtraction imaging (DSA) and intravascular imaging with optical coherence tomography were obtained...
September 2018: Neurointervention
https://www.readbyqxmd.com/read/30169782/precision-of-verifynow-p2y12-assessment-of-clopidogrel-response-in-patients-undergoing-cerebral-aneurysm-flow-diversion
#6
Matthew T Bender, David A Zarrin, Jessica K Campos, Bowen Jiang, Arun Chandra, Chau D Vo, Justin M Caplan, Judy Huang, Rafael J Tamargo, Li-Mei Lin, Geoffrey P Colby, Alexander L Coon
Background: Dual antiplatelet therapy (DAT), most commonly with aspirin and Clopidogrel, is the standard of care for intracranial stenting, including flow diversion. Clopidogrel response varies by individual. Objective: To investigate the real-world precision of VerifyNow P2Y12 assessment (Accumetrics, San Diego, California) of Clopidogrel response. Methods: Using a prospectively-collected, IRB-approved cerebral aneurysm database 643 patients were identified who were treated with the Pipeline embolization device from 2011 to 2017...
August 29, 2018: Neurosurgery
https://www.readbyqxmd.com/read/30149155/statin-therapy-and-diabetes-do-not-affect-aneurysm-occlusion-or-clinical-outcomes-after-pipeline-embolization-device-treatment-a-preliminary-study
#7
Mohamed M Salem, Georgios A Maragkos, Alejandro Enriquez-Marulanda, Luis Ascanio, Krishnan Ravindran, Abdulrahman Y Alturki, Christopher S Ogilvy, Ajith J Thomas, Justin M Moore
BACKGROUND: The effect of statins and diabetes on angiographic and clinical outcomes in aneurysms treated with pipelines has not been adequately reported. Our aim is to assess the effect of concurrent statin medications and diabetes mellitus (DM) on aneurysm occlusion status and outcomes in patients treated with the pipeline embolization device. METHODS: A retrospective review of our institution's database of aneurysms treated with the pipeline embolization device between 2013 and 2017 was conducted...
August 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30103059/morphologic-feature-elongation-can-predict-occlusion-status-following-pipeline-embolization-of-intracranial-aneurysms
#8
Yupeng Zhang, Chao Ma, Shikai Liang, Peng Yan, Fei Liang, Feng Guo, Chuhan Jiang
OBJECTIVE: To explore whether computed morphologic features can be used as independent predictors of incomplete occlusion of aneurysms treated with the Pipeline embolization device. METHODS: From January 2016 to September 2017, 58 patients with 58 aneurysms were treated with the Pipeline embolization device. Aneurysms were manually segmented from the Digital Imaging and Communications in Medicine file, and we calculated 16 shape features voxel by voxel on the segmented aneurysm image...
August 10, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30081693/flow-diverter-for-endovascular-treatment-of-intracranial-mirror-segment-internal-carotid-artery-aneurysms
#9
Anna Luisa Kühn, Peter Kan, Visish Srinivasan, David E Rex, Katyucia de Macedo Rodrigues, Mary C Howk, Ajay K Wakhloo, Ajit S Puri
Background To evaluate the feasibility and efficacy of the pipeline embolization device in the treatment of unruptured intracranial mirror segment aneurysms. Methods Out of a total of 338 subjects, 14 were identified harboring a total of 32 internal carotid artery mirror segment aneurysms that were treated with the pipeline embolization device and were consecutively enrolled into our study. We collected data on patient demographics, modified Rankin scale (mRS) at admission, aneurysm characteristics, clinical outcome at discharge, 3-9 and at 12-18 months as well as angiography results at follow-up...
August 6, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/30075266/pipeline-embolization-device-with-shield-technology-for-intracranial-aneurysms-an-initial-united-states-experience
#10
Christoph J Griessenauer, Oded Goren, Shamsher S Dalal, Clemens M Schirmer
BACKGROUND: Thromboembolic complications remain a major reason for morbidity and mortality after flow diversion along with hemorrhagic complications not limited to the brain predicated on the prolonged need for dual antiplatelet therapy. Surface modification to decrease thrombogenicity and accelerate aneurysm occlusion is a promising alteration to mitigate those risks. The Pipeline embolization device (PED) with Shield technology possesses such characteristics, but is currently not approved in the United States...
July 31, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30037958/mural-destabilization-after-aneurysm-treatment-with-a-flow-diverting-device-a-report-of-two-cases
#11
Timothy Hampton, Donal Walsh, Christos Tolias, David Fiorella
BACKGROUND: Flow-diverting stents have demonstrated great promise for the treatment of cerebral aneurysms; however, clinical experience with the devices remains very preliminary. We present two cases of spontaneous delayed complications-one fatal aneurysm rupture and one symptomatic increase in aneurysm volume-following the treatment of intradural aneurysms with the Pipeline Embolization Device (PED). PRESENTATION/INTERVENTION: Two patients with unruptured, intradural aneurysms of the carotid artery underwent uneventful treatment with the PED (eV3, Irvine, California, USA)...
July 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/30037946/curative-cerebrovascular-reconstruction-with-the-pipeline-embolization-device-the-emergence-of-definitive-endovascular-therapy-for-intracranial-aneurysms
#12
REVIEW
D Fiorella, P Lylyk, I Szikora, M E Kelly, F C Albuquerque, C G McDougall, P K Nelson
Endovascular, endosaccular, coil embolization has emerged as an established therapy for both ruptured and unruptured cerebral aneurysms. However, many aneurysms are not cured using conventional endovascular techniques. Coil embolization often results in incomplete aneurysm occlusion or recanalization in the ensuing months after treatment. The Pipeline embolization device (PED; Chestnut Medical) represents a new generation endoluminal implant which is designed to treat aneurysms by reconstructing the diseased parent artery...
July 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/30037945/commentary-on-curative-cerebrovascular-reconstruction-with-the-pipeline-embolization-device-the-emergence-of-definitive-endovascular-therapy-for-intracranial-aneurysms
#13
Christophe Cognard
No abstract text is available yet for this article.
July 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/30033786/cerebral-hemodynamics-and-intracranial-aneurysms-reflecting-on-pipeline-embolization-devices
#14
Wesley K Lefferts, Kevin S Heffernan
No abstract text is available yet for this article.
January 1, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/30032522/-efficacy-of-pipeline-embolization-device-in-the-treatment-of-large-and-giant-intracranial-aneurysms
#15
Y K He, H Li, W X Bai, T X Li, W J Jiang, H C Qiu
Objective: To summarize the safety and efficacy of Pipeline embolization device in the treatment of large and giant intracranial aneurysms (maximum diameter ≥ 10 mm). Methods: The clinical and imaging data of 22 patients with intracranial aneurysms treated by Pipeline Embolization Device (PED) from February 2015 to July 2016 in the Zhengzhou University People's Hospital were retrospectively analyzed. The results about postoperative clinical and imaging follow-up and complications were evaluated. Results: The PED were successfully implanted in 22 patients with 22 intracranial aneurysms...
July 17, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30031197/histopathological-demonstration-of-subacute-endothelialization-following-aneurysm-retreatment-with-the-pipeline-embolization-device
#16
Krishnan Ravindran, Marcello DiStasio, Roger Laham, Christopher S Ogilvy, Ajith J Thomas, Paul A VanderLaan, Abdulrahman Y Alturki
BACKGROUND: Endothelial cell coverage along the Pipeline embolization device (PED) is 1 of 2 primary proposed mechanisms of action of the device, along with induction of intra-aneurysmal thrombosis. The temporal course of endothelialization following device deployment is poorly understood in human patients. CASE DESCRIPTION: A 63-year-old female with a persistent aneurysm in the communicating segment of the internal carotid artery was treated with a second PED 14 months after the deployment of a first PED and subsequently developed a fatal intraparenchymal hemorrhage at 3 weeks postimplantation...
October 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30026147/use-of-flow-diversion-for-the-treatment-of-distal-circulation-aneurysms-a-multicohort-study
#17
MULTICENTER STUDY
Krishnan Ravindran, Alejandro Enriquez-Marulanda, Peter T M Kan, Leonardo Renieri, Nicola Limbucci, Salvatore Mangiafico, Mohamed M Salem, Abdulrahman Y Alturki, Justin M Moore, Christopher S Ogilvy, Ajith J Thomas
OBJECTIVE: The safety and efficacy of flow diversion for distal circulation aneurysms of the cerebral vasculature has not been well evaluated. The objective of this study was to assess the use of flow diversion for distal circulation aneurysms (defined as at or beyond the M1, P1, and A1 segments of the middle cerebral artery, posterior cerebral artery, and anterior cerebral artery, respectively) in an international multicenter cohort. METHODS: Clinical and radiologic records from all patients undergoing flow diversion treatment of distal circulation aneurysms at 3 academic centers (2 in the USA and 1 in Europe) from 2014 until 2017 were retrospectively reviewed...
October 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30004284/proposal-of-a-follow-up-imaging-strategy-following-pipeline-flow-diversion-treatment-of-intracranial-aneurysms
#18
Raghav Gupta, Christopher S Ogilvy, Justin M Moore, Christoph J Griessenauer, Alejandro Enriquez-Marulanda, Madeline Leadon, Nimer Adeeb, Luis Ascanio, Georgios A Maragkos, Abhi Jain, Philip G R Schmalz, Abdulrahman Y Alturki, Kimberly Kicielinski, Clemens M Schirmer, Ajith J Thomas
OBJECTIVE There is currently no standardized follow-up imaging strategy for intracranial aneurysms treated with the Pipeline embolization device (PED). Here, the authors use follow-up imaging data for aneurysms treated with the PED to propose a standardizable follow-up imaging strategy. METHODS A retrospective review of all patients who underwent treatment for ruptured or unruptured intracranial aneurysms with the PED between March 2013 and March 2017 at 2 major academic institutions in the US was performed...
July 13, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29999443/microhemorrhagic-transformation-of-ischemic-lesions-on-t2-weighted-magnetic-resonance-imaging-after-pipeline-embolization-device-treatment
#19
Ryuta Nakae, Masaya Nagaishi, Yosuke Kawamura, Yoshihiro Tanaka, Akio Hyodo, Kensuke Suzuki
OBJECTIVE The authors sought to demonstrate that hemorrhagic transformation of ischemic lesions is the main cause of delayed intracerebral hemorrhage (ICH) after Pipeline embolization device (PED) treatment and to estimate the rate of hemorrhagic transformation of new postprocedure ischemic lesions. METHODS Patients who underwent PED placement (PED group) from November 2015 to March 2017 or stent-mediated embolization (EN group) from December 2010 to October 2015 were retrospectively analyzed. Pre- and postprocedural MR images and 6-month follow-up MR images for each patient were scored for the presence of postprocedural bland ischemic and hemorrhagic lesions using diffusion-weighted MRI (DWI) and T2*-weighted MRI (T2*WI), respectively...
June 1, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29957112/flow-diversion-and-microvascular-plug-occlusion-for-the-treatment-of-a-complex-unruptured-basilar-superior-cerebellar-artery-aneurysm-case-report
#20
Jan-Karl Burkhardt, Howard A Riina, Omar Tanweer, Peyman Shirani, Eytan Raz, Maksim Shapiro, Peter Kim Nelson
The authors present the unusual case of a complex unruptured basilar artery terminus (BAT) aneurysm in a 42-year-old symptomatic female patient presenting with symptoms of mass effect. Due to the fusiform incorporation of both the BAT and left superior cerebellar artery (SCA) origin, simple surgical or endovascular treatment options were not feasible in this case. A 2-staged (combined deconstructive/reconstructive) procedure was successfully performed: first occluding the left SCA with a Pipeline embolization device (PED) coupled to a microvascular plug (MVP) in the absence of antiplatelet coverage, followed by reconstruction of the BAT by deploying a second PED from the right SCA into the basilar trunk...
June 29, 2018: Journal of Neurosurgery
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