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Ectopic pregnancy

L Grode, B H Bech, O Plana-Ripoll, M Bliddal, I E Agerholm, P Humaidan, C H Ramlau-Hansen
STUDY QUESTION: How does celiac disease (CD) influence women's reproductive life, both prior to and after the diagnosis? SUMMARY ANSWER: Prior to the diagnosis of CD, an increased risk of adverse pregnancy outcomes was seen, whereas after the diagnosis, no influence on reproductive outcomes was found. WHAT IS KNOWN ALREADY: CD has been associated with several conditions influencing female reproduction and pregnancy outcomes including spontaneous abortion and stillbirth...
June 15, 2018: Human Reproduction
Fang Fang, Yu Bai, Yu Zhang, Andrew Faramand
OBJECTIVE: To determine the effect of the using oil-soluble contrast material (OSCM) vs. water-soluble contrast material (WSCM) for hysterosalpingography on pregnancy rates in infertile women. DESIGN: Systematic review and meta-analysis. SETTING: Not applicable. PATIENT(S): Infertile women. INTERVENTION(S): We included randomized controlled trials comparing pregnancy outcomes in women with infertility undergoing hysterosalpingography using OSCM and WSCM...
June 13, 2018: Fertility and Sterility
Tianyang Gao, Yingqiu Liang, Haiyu Tang, Li Quan
OBJECTIVE: This study was to determinate the expression of Tspan5 in tubal ectopic implantation sites and to explore the correlation of the expressive level of Tspan5 at maternal-fetal interface and the occurrence of tubal ectopic pregnancy. STUDY DESIGN: This is a retrospective study. Trophoblastic and endometrial tissues were collected from tubal ectopic pregnancy(Total of 40), and intrauterine pregnancy(Total of 41), who had voluntary abortion, non-pregnancy women(Total of 12), who recieved an diagnostic uterine curettage before IVF-ET for male infertility...
June 5, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Lakshmy Ravi Selvaraj, Nity Rose, Meenakshi Ramachandran
Cesarean scar pregnancy (CSP) is a rare kind of ectopic pregnancy implanted in the previous cesarean scar and has an increasing incidence over the past 30 years. As the suspicion is low, the diagnosis may be delayed or misinterpreted in ultrasound, leading to treatment strategies that might end up in uterine rupture or hysterectomy. The objective here is to review the ultrasound findings in CSP with varied presentations. Transabdominal and transvaginal sonography combined with color Doppler is a reliable tool for the diagnosis of CSP...
June 2018: Journal of Obstetrics and Gynaecology of India
Agustin L Lujan, Diego O Croci, Julián A Gambarte Tudela, Antonella D Losinno, Alejandro J Cagnoni, Karina V Mariño, María T Damiani, Gabriel A Rabinovich
Chlamydia trachomatis ( Ct ) constitutes the most prevalent sexually transmitted bacterium worldwide. Chlamydial infections can lead to severe clinical sequelae including pelvic inflammatory disease, ectopic pregnancy, and tubal infertility. As an obligate intracellular pathogen, Ct has evolved multiple strategies to promote adhesion and invasion of host cells, including those involving both bacterial and host glycans. Here, we show that galectin-1 (Gal1), an endogenous lectin widely expressed in female and male genital tracts, promotes Ct infection...
June 11, 2018: Proceedings of the National Academy of Sciences of the United States of America
L Pirtea, O Balint, C Secosan, D Grigoras, R Ilina
STUDY OBJECTIVE: To present a case of a cesarean scar ectopic pregnancy treated by laparoscopic resection followed by isthmocele repair. DESIGN: Case report SETTINGS: University Gynecology Clinic of the Emergency Clinical City Hospital Timișoara, România. BACKGROUND: Cesarean scar pregnancy is a rare form of ectopic pregnancy. In the last years its prevalence has risen due to the increasing number of cesarean section. An early diagnosis can lead to an early management decreasing the risk of life-threatening complication such as uterine rupture and massive haemorrhage...
June 8, 2018: Journal of Minimally Invasive Gynecology
Kausar Jabeen, Jagadeeswari Karuppaswamy
The aim of this paper is to review the diagnosis and treatment of patients with a caesarean scar pregnancy (CSP), who have been managed at our unit, as well as to evaluate the effectiveness of the non-surgical treatment options. Twenty-six cases were identified over a period of 5 years and 4 months (January 2012 until April 2017). The main outcome measures were a number of previous caesarean births, a method of diagnosis of CSP, the mode of treatment and the outcome. The diagnostic criteria on the ultrasound were an empty uterine cavity and cervical canal, the presence of a gestational sac anterior to the isthmic portion of the uterus, an absent or thinned (<5 mm) myometrial thickness between the gestational sac and the bladder, with a peri-trophoblastic circulation around the gestational sac with the colour flow Doppler examination...
June 8, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Aubert Agostini, Patrice Crochet
Cesarean scar pregnancy (CSP) is a rare condition that is often first diagnosed in an emergency setting.. The treatment of CSP varies depending on clinical expertise and the protocols of the local service. For this reason, it is difficult to carry out studies comparing the various treatments that are available. This article is protected by copyright. All rights reserved.
June 7, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
Melissa A Parks, Kurt T Barnhart, David L Howard
BACKGROUND: When managing a nonviable pregnancy of unknown location (PUL), a debate has emerged in the literature whether to perform uterine curettage for definitive diagnosis of pregnancy location or administer methotrexate for a presumed ectopic pregnancy. The purpose of this study is to describe the treatment patterns when managing a PUL. METHODS: A prospective, anonymous Internet based-electronic survey of PUL case scenarios was administered to a random sample of physicians across the United States...
June 6, 2018: Gynecologic and Obstetric Investigation
Tanya L Glenn, James Bembry, Austin D Findley, Jerome L Yaklic, Bala Bhagavath, Pascal Gagneux, Steven R Lindheim
Importance: Cesarean scar ectopic pregnancy (CSEP) has a high rate of morbidity with nonspecific signs and symptoms making identification difficult. The criterion-standard treatment of CSEP has been subject to debate. Objective: This review defines CSEP, discusses pathogenesis and diagnosis, and compares treatment options and outcomes. Evidence Acquisition: A literature review was performed utilizing the term cesarean scar ectopic pregnancy and subsequently selecting only meta-analyses and systematic reviews...
May 2018: Obstetrical & Gynecological Survey
Asma Tariq, Maria O'Rourke, Steven J Carstens, Vicken Y Totten
We describe an unusual ruptured ectopic pregnancy. The unique features of the case include abdominal pain without vaginal bleeding; cervical implantation and a placenta accreta; and the late presentation at 16 weeks of gestation without prior symptoms. Both the initial point-of-care ultrasound and the formal ultrasound were interpreted as showing an intrauterine pregnancy. The clinical presentation was misleading; the correct diagnosis was made by magnetic resonance imaging. We show the ultrasonic images. We discuss cervical ectopic pregnancies, their diagnosis and management...
May 2018: Clinical practice and cases in emergency medicine
Piotr Pędraszewski, Edyta Wlaźlak, Wojciech Panek, Grzegorz Surkont
Diagnosis and treatment of ectopic cesarean scar pregnancy has become a challenge for contemporary obstetrics. With an increase in the number of pregnancies concluded with a cesarean section and with the development of transvaginal ultrasonography, the frequency of cesarean scar pregnancy diagnoses has increased as well. The aim of the study is to evaluate various diagnostic methods (ultrasonography in particular) and analyze effective treatment methods for cesarean scar pregnancy. An ultrasound scan, Doppler examination and magnetic resonance imaging are all useful in early detection of asymptomatic cesarean scar pregnancy, thus enabling effective treatment and preservation of fertility...
March 2018: Journal of Ultrasonography
Ma Li, Chen Kailun
No abstract text is available yet for this article.
May 25, 2018: Journal of Minimally Invasive Gynecology
Suxia Zhang, Qian Sun, Xiaojuan Jiang, Fengchun Gao
The clinical significance of hsa-mir-1247 and hsa-mir-1269a expression in ectopic pregnancy due to salpingitis was investigated. Eighty patients with ectopic pregnancy diagnosed by ultrasonography who were admitted to Jinan Maternity and Child Care Hospital from January 2012 to May 2012 were enrolled in this study. To the observation group were assigned 35 patients whose ectopic pregnancy was due to salpingitis. The remaining 45 patients whose ectopic pregnancy was due to reasons other than endometriosis were assigned to the control group...
June 2018: Experimental and Therapeutic Medicine
N Spillane, S Meaney, K O' Donoghue
OBJECTIVE: Ectopic pregnancy can become a life threatening condition. Due to the specific nature of Ectopic pregnancy the grief experienced may well be overlooked compared to other pregnancy losses. Fertility concerns for the future and recovery from surgical or medical treatment may instead become the focus of care. The objective of this study was to gain insight into women's experience of Ectopic pregnancy. STUDY DESIGN: A qualitative semi-structured interview format was utilised...
June 2018: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
Xin Chen, Haiyuan Liu, Dawei Sun, JunJi Zhang, Qingbo Fan, Honghui Shi, Jinghe Lang
Natural orifice transluminal endoscopic surgery (NOTES) is a relatively new technique currently being studied around the world. Between June 2015 and June 2017, 12 patients diagnosed with ectopic pregnancy underwent transvaginal NOTES to remove their fallopian tubes. All 12 surgeries were completed successfully. The median age of patients was 33 years (range, 28-42) and the median body mass index was 23.47 (range, 20.55-27.68). The median duration of amenorrhea was 53 days (range, 41-60). The median serum beta-HCG was 8887 U/ml (range, 392-25,695)...
May 23, 2018: Journal of Minimally Invasive Gynecology
Emmanuel N Kontomanolis, Sofia Kalagasidou, Zacharias Fasoulakis
Diagnosis of ectopic pregnancy relies on both ultrasound findings and human chorionic gonadotropin (hCG) measurements but due to the need for serial tests, tubal rupture and death represent major maternal and fetal risks. Early detection of ectopic pregnancy is essential and thus a noninvasive diagnostic tool seems crucial for the prevention of adverse effects since studies suggest there is a specific relationship between ectopic pregnancy and increasing microRNA factors. Human fluids in women with ectopic pregnancy reveal a particular change in comparison to healthy women...
March 19, 2018: Curēus
Zeynep Aslı Oskovi Kaplan, Ali Levent Şirvan, Hasan Onur Topçu
Incidence of molar pregnancy is 1-3/1000 pregnancies. Invasive mole is a local invasive form of gestational trophoblastic neoplasias which is mostly seen in reproductive age and usually follows a molar pregnancy and rarely has an initial presentation. Ectopic pregnancy in rudimentary uterine horn is extremely rare and is seen in 1/100,000 - 140,000 pregnancies. Invasive mole has seldom been reported in ectopic localizations but not in a patient with Müllerian duct anomaly. Here we represent a case of invasive mole in a reproductive age patient with unicornuate uterus and rudimentary communicating uterine horn...
May 2018: Journal of Experimental Therapeutics & Oncology
An-Shine Chao, Yao-Lung Chang, Lan-Yan Yang, Angel Chao, Wei-Yang Chang, Sheng-Yuan Su, Chin-Jung Wang
The incidence of uterine rupture through a previous cesarean scar (CS) is declining as a result of a lower parity and fewer options for vaginal birth after cesarean. However, uterine ruptures attributable to other causes that traumatize the myometrium are on the rise. To determine whether changes in the causes of uterine rupture had occurred in recent years, we retrospective retrieved the clinical records of all singletons with uterine rupture observed in the delivery room of a Taiwanese tertiary obstetric center over a 15-year period...
2018: PloS One
Jicai Wang, Zhilei Su, Shounan Lu, Wen Fu, Zhifa Liu, Xingming Jiang, Sheng Tai
PURPOSE: To summarize the appropriate diagnostic methods and therapeutic options for primary hepatic pregnancy (PHP). METHODS: Literature searches were performed in Pubmed, Web of Science, Cochrane Library and Embase databases (1956-2017), using the following search terms: primary hepatic pregnancy, hepatic pregnancy, liver pregnancy, hepatic ectopic pregnancy and intrahepatic pregnancy. Further literature was confirmed through cross-referencing. RESULTS: Thirty-one cases were reviewed and collected...
May 21, 2018: Archives of Gynecology and Obstetrics
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