keyword
MENU ▼
Read by QxMD icon Read
search

Vulvar pathology

keyword
https://www.readbyqxmd.com/read/27882758/-vulvar-squamous-precancerous-lesions-history-and-current-state-of-the-topic
#1
L Ševčík, P Škapa, Y Vantuchová, V Benčík
This review article discribes the genesis and development of vulvar squamous precancerous lesions terminology and discusses the consensus of the International Society for the Study of Vulvovaginal Disease, the American Society for Colposcopy and Cervical Pathology, College of American Pathologists and the World Health Organization on the current terminology. The article describes the different types of vulvar squamous precancerous lesions, according to their etiology, incidence and malignant potential.
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27865454/does-a-groin-node-dissection-in-vulvar-cancer-affect-groin-recurrence-and-overall-survival-results-from-a-population-based-cohort-study
#2
Lilian T Gien, Rinku Sutradhar, Gillian Thomas, Allan Covens, Laurie Elit, Eileen Rakovitch, Anthony Fyles, Mahmoud A Khalifa, Ying Liu, Lisa Barbera
BACKGROUND: To determine, in a population-based cohort of vulvar cancer patients, if groin node dissection (GND) decreases the risk of groin recurrence and increases overall survival. METHODS: This population-based retrospective cohort study includes all cases of invasive squamous cell carcinoma identified in a provincial cancer registry from 1998 to 2007. Data collection was completed for all clinical and pathologic factors by chart abstraction. Cumulative incidence functions for recurrence were estimated, accounting for death before recurrence as a competing risk...
November 16, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27844049/sebaceous-carcinoma-of-the-vulva-a-case-report-and-review-of-the-literature
#3
Stephanie A Sullivan, Arthur-Quan Tran, Siobhan O'Connor, Paola A Gehrig
•Sebaceous carcinoma (SC) is rare with only nine cases reported in the literature.•Extraocular SC likely has similar prognosis to ocular SC.•Reporting of vulvar SC should include detailed pathologic information so that risk factor associations can be made.
November 2016: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/27834349/differentiated-exophytic-vulvar-intraepithelial-lesions-are-genetically-distinct-from-keratinizing-squamous-cell-carcinomas-and-contain-mutations-in-pik3ca
#4
Jaclyn C Watkins, Brooke E Howitt, Neil S Horowitz, Lauren L Ritterhouse, Fei Dong, Laura E MacConaill, Elizabeth Garcia, Neal I Lindeman, Larissa J Lee, Ross S Berkowitz, Marisa R Nucci, Christopher P Crum
Human papillomavirus-negative keratinizing vulvar cancers typically harbor TP53 mutations as do their precursors, differentiated vulvar intraepithelial neoplasia. However, atypical verruciform proliferations are also associated with these malignancies and their pathogenesis is poorly understood. This study compared 11 atypical verruciform lesions, including atypical verruciform hyperplasia, vulvar acanthosis with altered differentiation, and verruciform lichen simplex chronicus, with 14 human papillomavirus-negative keratinizing squamous cell carcinomas...
November 11, 2016: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/27832673/extramammary-paget-disease-of-the-vulva-case-report
#5
Bianca Ruschel Hillmann, Amanda Amaro Pereira, Luiz Fernando Sommacal
Extramammary Paget disease (EPD) is a rare malign neoplasm that may affect the vulva and has manifestations common to benign diseases such as itching, pain and eczema. This leads to delay in diagnosis and consequent worse prognosis. The definitive diagnosis is obtained by biopsy of the vulva, which shows Paget cells. The treatment of choice is wide excision with margins, which leads to sequelae, functional and aesthetic. Recurrence is common. This article reports the case of a 48-year-old female patient with history of vulvar itching for the past 2 years, who had been submitted to various treatments for benign pathologies...
October 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/27801760/the-prevalence-of-lichen-sclerosus-in-patients-with-vulvar-squamous-cell-carcinoma
#6
Jonathan J Davick, Megan Samuelson, James T Krone, Colleen K Stockdale
Women with vulvar lichen sclerosus (LS) have an increased risk of developing differentiated vulvar intraepithelial neoplasia and vulvar squamous cell carcinoma (SCC). Our primary aim was to determine the prevalence of LS among women with vulvar SCC. All patients who underwent excision for invasive SCC of the vulva from January 1, 2009 to December 31, 2013 were identified by searching our institution's electronic laboratory information system (n=111). The vulvar excision specimens from these patients were reviewed for the presence of adjacent LS...
October 31, 2016: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/27763794/evaluation-of-the-vulvar-cancer-histology-code-reported-by-central-cancer-registries-importance-in-epidemiology
#7
David A Siegel, Reda Wilson, Edward J Wilkinson, Julia W Gargano, Meg Watson, Brenda Y Hernandez, Marc T Goodman, Charles F Lynch, Elizabeth R Unger, Mona Saraiya
CONTEXT: -Knowing the subtype of vulvar cancer histology is important for estimating human papillomavirus-related cancer etiology. Surveillance of human papillomavirus-related vulvar cancers informs public health decisions related to vaccination against human papillomavirus. OBJECTIVE: -To assess the accuracy of registry classifications of vulvar cancer and determine the histologic classification of cases reported as not otherwise specified. DESIGN: -Pathology specimens were collected from Florida, Iowa, and Hawaii cancer registries...
October 20, 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27759697/anogenital-mammary-like-glands-a-study-of-their-normal-histology-with-emphasis-on-glandular-depth-presence-of-columnar-epithelial-cells-and-distribution-of-elastic-fibers
#8
Anastasia M Konstantinova, Liubov Kyrpychova, Irena E Belousova, Dominic V Spagnolo, Denisa Kacerovska, Michal Michal, Katrin Kerl, Dmitry V Kazakov
The normal histology of anogenital mammary-like glands (AGMLG) has been studied previously, but some aspects, including glandular depth, presence of columnar epithelium resembling columnar cell change/hyperplasia as defined in mammary pathology, and distribution of elastic fibers, have not been previously investigated. To address these issues, we studied 148 AGMLG identified in 133 paraffin blocks sampled from 64 vulvar wide excision or vulvectomy specimens (64 patients, various indications for surgery). The depth of AGMLG ranged from 0...
October 18, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27629126/retrospective-evaluation-of-clinical-and-pathological-features-as-well-as-diagnostic-and-treatment-protocols-of-primary-vaginal-malignancy
#9
Gozde Kulhan, Mehmet Kulhan, Umit Nayki, Cenk Nayki, Pasa Ulug, Emrah Akkaya, Onur S Aldemir, Yusuf Yildirim, Mehmet Sipahi
OBJECTIVES: Our study aimed to determine the epidemiological characteristics and diagnostic and treatment protocols of primary vaginal carcinoma. Also, we compared the clinical and pathological features of primary vaginal carcinoma which intersect with cervical and vulvar carcinomas. MATERIAL AND METHODS: Sixteen patients with primary vaginal carcinoma, admitted to the Department of Gynecologic Oncology, Izmir Tepecik Training and Research Hospital between January 1983 and December 2012, were evaluated retrospectively...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27550403/groin-lymph-node-detection-and-sentinel-lymph-node-biopsy-in-vulvar-cancer
#10
Chieko Sakae, Ken Yamaguchi, Noriomi Matsumura, Hidekatsu Nakai, Yumiko Yoshioka, Eiji Kondoh, Junzo Hamanishi, Kaoru Abiko, Masafumi Koshiyama, Tsukasa Baba, Aki Kido, Masaki Mandai, Ikuo Konishi
OBJECTIVE: To identify suitable diagnostic tools and evaluate the efficacy of sentinel lymph node (SLN) biopsy for inguinal lymph node metastasis in vulvar cancer. METHODS: Data from 41 patients with vulvar cancer were evaluated retrospectively, including magnetic resonance imaging (MRI) measurements, SLN biopsy status, groin lymph node metastasis, and prognosis. RESULTS: SLN biopsy was conducted in 12 patients who had stage I to III disease...
November 2016: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/27513080/the-added-value-of-pathology-review-in-vulva-cancer-results-from-a-population-based-cohort-study
#11
Lisa Barbera, Lilian T Gien, Rinku Sutradhar, Gillian Thomas, Al Covens, Laurie Elit, Anthony Fyles, Eileen Rakovitch, Ying Liu, Mahmoud Khalifa
We conducted a population-based patterns of care study of vulvar carcinoma. This paper describes the changes in reporting based on pathology review. This is a retrospective population-based cohort study. We obtained all pathology records available from the provincial cancer registry for primary invasive squamous cell carcinoma of the vulva diagnosed between 1998 and 2007. Pathology reviews were conducted centrally by a group of gynecologic pathologists and were identified during abstraction. Corresponding original reports were matched to pathology review reports based on accession numbers...
August 10, 2016: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/27365105/genital-melanoma-prognosis-factors-and-treatment-modality
#12
Domenico Ferraioli, Gery Lamblin, Patrice Mathevet, Jessika Hetu, Isabelle Berakdar, Frederic Beurrier, Nicolas Chopin
PURPOSE: Genital melanoma is a rare pathology. We present the experience of two comprehensive cancer centers in Lyon (France) in the management of genital melanoma in order to identify prognostic factors and optimal treatments. METHODS: Between April 1992 and Mars 2014, 16 patients with a primary genital melanoma were referred to our department. Nine patients presented a vaginal melanoma, six vulvar melanomas and only one cervical melanoma. The median dimension of the lesion was 33...
June 30, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27359057/mir-223-5p-works-as-an-oncomir-in-vulvar-carcinoma-by-tp63-suppression
#13
Beatriz de Melo Maia, Iara Santana Rodrigues, Erica Mie Akagi, Nayra Soares do Amaral, Hui Ling, Paloma Monroig, Fernando Augusto Soares, George Adrian Calin, Rafael Malagoli Rocha
MiR-223-5p has been previously mentioned to be associated with tumor metastasis in HPV negative vulvar carcinomas, such as in several other tumor types. In the present study, we hypothesized that this microRNA would be important in vulvar cancer carcinogenesis and progression. To investigate this, we artificially mimicked miR-223-5p expression in a cell line derived from lymph node metastasis of vulvar carcinoma (SW962) and performed in vitro assays. As results, lower cell proliferation (p < 0.01) and migration (p < 0...
June 23, 2016: Oncotarget
https://www.readbyqxmd.com/read/27327194/pathologic-features-of-aggressive-vulvar-carcinoma-are-associated-with-epithelial-mesenchymal-transition
#14
Emily R Holthoff, Horace Spencer, Thomas Kelly, Steven R Post, Charles M Quick
Factors contributing to aggressive behavior in vulvar squamous cell carcinoma (vSCC) are poorly defined; however, a recent study has shown that vSCCs with an infiltrative pattern of invasion and fibromyxoid stroma are associated with worse outcomes than tumors with a pushing or nested pattern of invasion and lymphoplasmacytic stroma. Epithelial-mesenchymal transition (EMT) has been associated with tumor progression in a number of malignancies, and this study proposes that EMT contributes to tumor aggressiveness in this subset of vSCC...
October 2016: Human Pathology
https://www.readbyqxmd.com/read/27274709/cellular-angiofibroma-of-the-vulva-a-poorly-known-entity-a-case-report-and-literature-review
#15
Mouna Khmou, Najat Lamalmi, Abderrahmane Malihy, Lamia Rouas, Zaitouna Alhamany
BACKGROUND: Cellular angiofibroma represents a newly described, site specific tumor. Histologically, CAF is a benign mesenchymal neoplasm characterized by two principal components: bland spindle cells and prominent small to medium-sized vessels with mural hyalinization. The indolent nature of the lesion is underscored by the uniformity of its constituent stromal cells, and their lack of nuclear atypia. Characterization by immunohistochemistry is helpful distinguishing Cellular angiofibroma from other mesenchymal lesions...
2016: BMC Clinical Pathology
https://www.readbyqxmd.com/read/27257093/lichen-sclerosus-incidence-and-risk-of-vulvar-squamous-cell-carcinoma
#16
Maaike C G Bleeker, Pascal J Visser, Lucy I H Overbeek, Marc van Beurden, Johannes Berkhof
BACKGROUND: The association between lichen sclerosus and vulvar squamous cell carcinoma (VSCC) has long been recognized, but large epidemiologic studies are lacking. METHODS: Data of women diagnosed with vulvar pathology in the Netherlands were retrieved from the Dutch Pathology Registry. All vulvar pathology reports of this historical cohort were reviewed to construct a research database, including 3,038 women with lichen sclerosus diagnosed between 1991 and 2011...
August 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27188975/atypical-location-of-a-bartholin-cyst-in-adolescence
#17
Mustafa Öztürk, Yakup Çil, Ferdi Kıncı, Hakan Çermik
BACKGROUND: Cystic lesions associated with the blockage of Bartholin gland ducts are frequently seen, but occurrence outside the normal vestibular localization is quite rare. CASE: A 16-year-old patient presented with a localized cystic lump approximately 4 cm in size on one of her labia minora. After an excision, she was diagnosed with an atypically localized Bartholin cyst. SUMMARY AND CONCLUSION: It is very difficult to make an early diagnosis for an atypically localized Bartholin cystic lesion in adolescence; it can be diagnosed only after a pathological examination...
October 2016: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/27158579/lung-metastasis-in-a-case-of-recurrent-poorly-differentiated-leiomyosarcoma-of-the-bartholin-gland-a-case-report-and-review-of-the-literature
#18
Fatimah Alnafisah, Joanne Alfieri
Vulvar neoplasms represent four percent of all gynecological cancers. While most cases of vulvar neoplasms are benign, two percent of patients present with malignant disease. We present the case of a 37-year-old premenopausal female who presented to an outside institution with a lump in her left vulva, which had progressively enlarged to the size of an egg. A wide local excision of the left vulva was performed, and the pathology revealed a high-grade sarcoma, not otherwise specified (NOS), with negative margins...
2016: Curēus
https://www.readbyqxmd.com/read/27141185/malignancies-in-a-renal-transplant-population-the-st-michael-s-hospital-experience
#19
R Saleeb, H Faragalla, G M Yousef, R Stewart, C J Streutker
INTRODUCTION: Previous publications have shown an increased incidence of various malignancies amongst renal transplant populations. The objective of this study was to analyze the rate and types of malignancies occurring in the St. Michael's Hospital renal transplant population and to determine whether our results were comparable to those previously published. METHODS: After approval by the hospital's research ethic board, review of the records and pathology of the 1584 patients in the renal transplant clinic database patients was performed...
April 2016: Urology Annals
https://www.readbyqxmd.com/read/27132089/factors-influencing-primary-treatment-of-midline-vulvar-cancers
#20
Lesley B Conrad, Steven A Conrad, David S Miller, Debra L Richardson, Siobhan Kehoe, Jayanthi S Lea
OBJECTIVES: Advanced vulvar cancers involving midline structures pose a therapeutic challenge. Our objectives were to review the management and outcomes, and identify factors influencing primary treatment modality. METHODS: Patients with midline vulvar cancers diagnosed from 1985 to 2012 were included in the analysis. Medical records were abstracted for demographics, clinico-pathological findings, treatment, and outcomes. Groin node status was defined by clinical findings or pathology...
July 2016: Gynecologic Oncology
keyword
keyword
16774
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"