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Salivary gland pathology

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https://www.readbyqxmd.com/read/28423973/neurological-involvement-of-igg4-related-disease-description-of-a-case-and-review-of-the-literature
#1
Marco Varrassi, Camilla Gianneramo, Francesco Arrigoni, Paolo Cerrone, Patrizia Sucapane, Carmine Marini, Alessandra Splendiani
IgG4-related disease is a recently discovered pathological entity, histologically characterised by fibrosis and IgG4-positive plasma cell infiltration. This condition may virtually involve every site of the organism, with a various range of clinical presentations. The most commonly affected organ is the pancreatic gland, but it can also involve the biliary tract, salivary and lacrimal glands, kidneys, orbital tissues, lymph nodes, lungs and many others. More recently, IgG4-related disease has been demonstrated to involve, in rare cases, also the central nervous system, with a pattern mainly characterised by hypertrophic pachymeningitis...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28413396/mammary-analogue-secretory-carcinoma-presenting-as-a-cervical-lymph-node-metastasis-of-unknown-primary-site-a-case-report
#2
Kensuke Suzuki, Masao Yagi, Akira Kanda, Yoshiki Kobayashi, Masaya Konishi, Chika Miyasaka, Takashi Tashiro, Hiroshi Iwai
BACKGROUND: Mammary analogue secretory carcinoma (MASC) is a pathological entity arising in the salivary glands first described by Skalova et al. [Am J Surg Pathol 2010;34: 599-608]. Here, we report the first case of MASC presenting as a cervical lymph node metastasis of unknown primary site together with a brief review of the literature. CASE REPORT: We present a 74-year-old male with a painless lump in his left neck. Based on the fine-needle aspiration cytological findings, a possible malignant tumor was suspected...
January 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28411376/nodular-oncocytic-hyperplasia-can-cytomorphology-allow-for-the-preoperative-diagnosis-of-a-nonneoplastic-salivary-disease
#3
Lisa M Rooper, Mine Onenerk, Momin T Siddiqui, William C Faquin, Justin A Bishop, Syed Z Ali
BACKGROUND: Nodular oncocytic hyperplasia (oncocytosis) of the salivary glands is a benign process that does not inherently require surgical excision. However, cytologic findings in fine-needle aspiration (FNA) of oncocytosis cases have not been well characterized previously, limiting preoperative identification. METHODS: All available cases of oncocytosis with corresponding FNA specimens were identified from the pathology archives of 3 academic institutions. Clinical, cytologic, and histologic findings were tabulated for all cases...
April 14, 2017: Cancer
https://www.readbyqxmd.com/read/28410601/the-diagnosis-and-management-of-nk-t-cell-lymphomas
#4
REVIEW
Eric Tse, Yok-Lam Kwong
Extranodal natural killer (NK)/T-cell lymphoma is an aggressive malignancy of putative NK-cell origin, with a minority deriving from the T-cell lineage. Pathologically, the malignancy occurs in two forms, extranodal NK/T-cell lymphoma, nasal type; and aggressive NK-cell leukaemia. Lymphoma occur most commonly (80%) in the nose and upper aerodigestive tract, less commonly (20%) in non-nasal areas (skin, gastrointestinal tract, testis, salivary gland), and rarely as disseminated disease with a leukemic phase...
April 14, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28390130/oral-diseases-a-14-year-experience-of-a-chilean-institution-with-a-systematic-review-from-eight-countries
#5
C Rivera, C Jones-Herrera, P Vargas, B Venegas, D Droguett
BACKGROUND: Retrospective studies to assess the distribution of oral diseases (ODs) are helpful in estimating the prevalence of oral diagnoses in the population, and thus help in preventive and curative services. Prevalence and frequency data for ODs are available from many countries, but information from Chile is scarce. MATERIAL AND METHODS: This study investigated the frequency of OD in a Chilean population. For this, we included all patients treated at the University of Talca (UTALCA, Chile) between 2001 and 2014...
April 8, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28390124/clear-cell-changes-in-salivary-gland-neoplasms-a-20-year-retrospective-study
#6
T Woods, S Fitzpatrick, D Cohen, M Islam, I Bhattacharyya
BACKGROUND: Clear cells are observed histopathologically in both benign and malignant neoplasms but their presence in salivary gland tumors has not been extensively documented. MATERIAL AND METHODS: With IRB approval, the archive of the University of Florida College of Dentistry oral pathology biopsy service was retrospectively searched from 1994-2014 for all benign and malignant salivary tumors. Epidemiological data, tumor location and duration, and type of tumor were recorded...
April 8, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28365866/retrospective-evaluation-of-paediatric-oral-biopsies-over-a-10-year-period-in-western-india
#7
S S Patil, U R Kontham, R K Kontham, A Chowdhery
AIM: This retrospective study reviewed the paediatric oral biopsies received over 10 years at a teaching hospital and dental college in India. It is important that paediatric dentists know the diagnostic tendencies of oral pathological conditions in children, and possess updated information for their diagnosis and treatment. METHODS: Biopsies of patients 17 years of age or younger were selected. Computerised data regarding age, gender, anatomic location, and histopathological diagnosis was retrieved and classified into nine categories...
April 1, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28359731/acute-submaxillitis-etiological-data-and-etiological-management
#8
C Bignet, J Carvalho, E Lemaire, A Charpiot
OBJECTIVES: The objective of the present study was to test the hypothesis that acute submaxillitis involves salivary duct obstruction. Obstacle characteristics and treatment were analyzed. MATERIAL AND METHODS: Patients presenting with an episode of acute submaxillitis between 2009 and 2015 were retrospectively included. All underwent salivary duct imaging and/or sialendoscopy, with pathologic examination if the salivary gland was removed for etiologic diagnosis...
March 27, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28345516/a-case-of-bilateral-megaducts-diagnostic-and-treatment-methods
#9
L Vatin, J M Foletti, C Collet, A Varoquaux, C Chossegros
INTRODUCTION: The pathology of the saliva glands comprises both tumoral and obstructive disorders. The latter include lithiasis, stenosis and megaduct. In this paper, we describe a clinical case of bilateral megaduct, a rare pathology, using sialo-MRI imaging and a conservative diagnostic-cum-therapeutic technique, sialendoscopy with dilation followed by catheterization. CLINICAL CASE: Our female patient presented oversized parotids with an unsightly deformation of the face (parotid ducts visible beneath the skin) and itchy cheeks, from which she had suffered for several years...
February 17, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28336186/variation-in-head-and-neck-cancer-care-in-the-netherlands-a-retrospective-cohort-evaluation-of-incidence-treatment-and-outcome
#10
M de Ridder, A J M Balm, R J Baatenburg de Jong, C H J Terhaard, R P Takes, M Slingerland, E Dik, R J E Sedee, J G A M de Visscher, H Bouman, S M Willems, M W Wouters, L E Smeele, B A C van Dijk
BACKGROUND: To explore variation in numbers and treatment between hospitals that treat head and neck cancer (HNC) in the Netherlands. MATERIAL AND METHODS: Patient, tumor and treatment characteristics were collected from the Netherlands Cancer Registry, while histopathological features were obtained by linkage to the national pathology record register PALGA. Inter-hospital variation in volume, stage, treatment, pathologically confirmed loco-regional recurrence and overall survival rate was evaluated by tumor site...
March 8, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28326216/an-unusual-clinical-presentation-of-solitary-fibrous-tumor-in-the-oral-cavity
#11
Everton Freitas de Morais, Deborah Gondim Lambert Moreira, Viviane Alves De Oliveira, Rodrigo Rodrigues Rodrigues, Adriano Rocha Germano, Roseana de Almeida Freitas
Solitary fibrous tumor is a rare neoplasm of mesenchymal origin that usually affects the pleura. This rarity becomes more relevant in the oral cavity since the clinical features are nonspecific. A 66-year-old female patient presented with a 3-month history of a swelling in the floor of the mouth, measuring 2 cm in greatest diameter, and pain symptomatology. Occlusal and panoramic radiographs showed no bone involvement. Ultrasonography of the submandibular and parotid salivary glands revealed normal morphology, dimensions, and echogenicity...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28325631/new-concepts-of-personalized-therapy-in-salivary-gland-carcinomas
#12
REVIEW
Gunter Keller, Diana Steinmann, Alexander Quaas, Viktor Grünwald, Stefan Janssen, Kais Hussein
Salivary gland carcinomas are rare tumours and therapy strategies are less standardized than in lung, gastric or breast cancer. Therapy is based on surgery, but not all carcinomas are completely resectable, e.g. because carcinomas often show infiltration of nerves. For further therapy decision pathology is recommended, but evaluation of potential targets for personalized therapy is not part of the routine panel. Many salivary gland carcinomas can be resistant to radio- and/or chemotherapy, which limits therapeutic options...
March 18, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28274671/second-opinion-oral-pathology-referrals-in-new-zealand
#13
B Seo, H M Hussaini, A M Rich
Referral for a second opinion is an important aspect of pathology practice, which reduces the rate of diagnostic error and ensures consistency with diagnoses. The Oral Pathology Centre (OPC) is the only specialist oral diagnostic centre in New Zealand. OPC provides diagnostic services to dentists and dental specialists throughout New Zealand and acts as a referral centre for second opinions for oral pathology specimens that have been sent to anatomical pathologists. The aim of this study was to review second opinion referral cases sent to the OPC over a 15-year period and to assess the levels of concordance between the original and final diagnoses...
April 2017: Pathology
https://www.readbyqxmd.com/read/28272678/clear-cell-myoepithelial-carcinoma-of-the-upper-lip-a-rare-case-report
#14
Swati Gotmare, Anish Gupta, Megha Jain, Mandavi Waghmare
Myoepithelial carcinomas are quite infrequent neoplasms and coupled with their diverse morphological appearance are interesting as far as diagnosis and management is concerned. They account for less than 1% of all salivary gland tumors. The variable morphologic appearance of myoepithelial carcinoma leads to a wide differential diagnosis, including primary salivary gland tumors and metastatic tumors. The prognosis of these tumors is not fair as they are locally aggressive and approximately one third of the patients die of the pathology...
February 4, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28249655/salivary-gland-pleomorphic-adenoma-in-the-netherlands-a-nationwide-observational-study-of-primary-tumor-incidence-malignant-transformation-recurrence-and-risk-factors-for-recurrence
#15
M H Valstar, M de Ridder, E C van den Broek, M M Stuiver, B A C van Dijk, M L F van Velthuysen, A J M Balm, L E Smeele
INTRODUCTION: Whereas salivary gland pleomorphic adenoma (SGPA) is the most common type of salivary gland tumor, little is known about its epidemiology because national cancer registries do not register this disease. OBJECTIVES: To establish SGPA incidence trends, rates of secondary malignant transformation and recurrence and associated factors in the Netherlands. MATERIALS AND METHODS: Data on incidence, epidemiology, secondary malignant transformation and recurrence were retrieved from the Dutch pathology registry (PALGA) for the years 1992, 1997, 2002, 2007, and 2012...
March 2017: Oral Oncology
https://www.readbyqxmd.com/read/28249649/systemic-therapy-in-metastatic-salivary-gland-carcinomas-a-pathology-driven-paradigm
#16
REVIEW
Salvatore Alfieri, Roberta Granata, Cristiana Bergamini, Carlo Resteghini, Paolo Bossi, Lisa F Licitra, Laura D Locati
Salivary gland carcinomas (SGCs) represent one of the most complex tumors from a pathological point of view. According to the World Health Organization (WHO) classification (2005), twenty-four malignant histotypes are recognized, almost all characterized by specific morphological and genetic features as well as by particular clinical behavior. Loco-regional relapse and distant metastases are quite common. Distant metastases are diagnosed in 25-55% of the patients and only 20% of them are alive after 5years...
March 2017: Oral Oncology
https://www.readbyqxmd.com/read/28247228/update-from-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumours-what-is-new-in-the-2017-who-blue-book-for-tumors-and-tumor-like-lesions-of-the-neck-and-lymph-nodes
#17
Nora Katabi, James S Lewis
The World Health Organization (WHO) 2017 Classification of Head and Neck Tumors ("Blue Book") will now include a new chapter on tumors and tumor-like lesions of the neck and lymph nodes, which was not included in the previous edition. Tumors and tumor-like lesions, including a variety of cysts and metastases, can arise in any component in the neck, including soft tissue, lymph nodes, and developmental remnants. The pathology and clinical features of metastatic carcinoma of unknown primary in the head and neck has changed dramatically in the last several years...
March 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28247223/update-from-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumours-hematolymphoid-tumours
#18
Noah A Brown, Kojo S J Elenitoba-Johnson
In 2017, the latest revision to the WHO Classification of Head and Neck Tumours will be released. Similar to the 2005 WHO, the codification of hematopoietic and lymphoid neoplasms of the head and neck is included within chapters pertaining to the nasal cavity and paranasal sinuses, the nasopharynx, the larynx, the oral cavity and oropharynx, the neck and the salivary glands. Herein, we describe both changes to the classification of hematolymphoid neoplasms of the head and neck since the 2005 WHO, as well as recent advances in our understanding of the underlying pathogenesis and molecular pathology of these neoplasms...
March 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28229827/anti-la-positive-anti-ro-negative-subset-of-primary-sj%C3%A3-gren-s-syndrome-anti-la-is-a-reality-but-is-the-disease
#19
Debashish Danda, Rohan Sharma, Dat Truong, Kristi A Koelsch, Biji T Kurien, Harini Bagavant, Umesh Deshmukh, C Erick Kaufman, David M Lewis, Donald U Stone, Lida Radfar, Astrid Rasmussen, Kathy L Sivils, Robert H Scofield
OBJECTIVES: To characterise the serological and clinical findings in primary Sjögren's syndrome in which anti-La was found without anti-Ro. We hypothesised that a significant portion of these are falsely negative for anti-Ro60. METHODS: Twenty-nine sera from primary Sjögren's syndrome patients were tested for antibodies directed against La and Ro. Anti-La was detected using bovine La treated with or without DNAase and RNAase to identify potential false positivity...
February 20, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28228909/igg4-related-disease-in-an-adolescent-with-radiologic-pathologic-correlation
#20
Renato Cesar Ferreira da Silva, Scott M Lieberman, Henry T Hoffman, Bruno Policeni, Amani Bashir, Richard J H Smith, T Shawn Sato
Immunoglobulin G4-related disease (IgG4RD) is an immune-mediated condition characterized by lymphoplasmacytic infiltrates and fibrosis of affected organs. IgG4RD may affect many different organs either individually or together in a multiorgan condition and, thus, incorporates a wide range of fibroinflammatory phenotypes with shared pathologic features. Although IgG4RD most commonly occurs in late adulthood, it may affect children and adolescents. Only one case of IgG4RD presenting as isolated submandibular gland involvement has been reported in the pediatric population...
March 2017: Radiology case reports
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