keyword
MENU ▼
Read by QxMD icon Read
search

Salivary gland pathology

keyword
https://www.readbyqxmd.com/read/29449722/current-usefulness-of-aspiration-cytology-fnac-in-the-head-and-neck-diagnosis
#1
S Dallari, P M Gusella, P Campanella, M Ciommi, P Pantanetti, E Tortato, A Castriotta
Background: Fine Needle Aspiration Cytology (FNAC) is a well established and widely used method for both a preliminary and sometime final non-invasive pathologic diagnosis. FNAC is a simple and inexpensive diagnostic tool and should represent the standard of care in developing and resource-poor countries while maintaining its diagnostic usefulness in developed and advanced ones. Methods: The concordance between preoperative FNAC and final histology was evaluated in 168 patients operated on at the Otorhinolaryngology Unit, "A...
December 2017: Pathologica
https://www.readbyqxmd.com/read/29442093/a-review-of-research-on-cytological-approach-in-salivary-gland-masses
#2
Arvind Babu Rajendra Santosh, Shobha Rani Bakki, Suvarna Manthapuri
To evaluate the diagnostic accuracy of fine-needle aspirations (FNAs) in salivary gland pathologies. A comprehensive literature search was conducted in the PubMed database using related Medical Subject Heading terms "sensitivity and specificity of FNA in salivary gland" and "diagnostic accuracy of FNA in salivary gland" for the period 1980-2016, and we found that 414 research studies had been published. PRISMA technology was utilized to prepare flow chart for displaying data search strategy...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29434341/hyalinizing-clear-cell-carcinoma-of-the-bronchial-glands-presentation-of-three-cases-and-pathological-comparisons-with-salivary-gland-counterparts-and-bronchial-mucoepidermoid-carcinomas
#3
Manabu Takamatsu, Yukiko Sato, Mariko Muto, Hiroko Nagano, Hironori Ninomiya, Rie Sakakibara, Satoko Baba, Seiji Sakata, Kengo Takeuchi, Sakae Okumura, Yuichi Ishikawa
Hyalinizing clear cell carcinoma of the bronchial glands is a very rare tumor. Since only five reports describing six tumors have been published to date, only a little is known about specific histologic findings and clinical features. Because of its rarity, hyalinizing clear cell carcinoma has not been described in the latest WHO classification of pulmonary tumors yet. Here we present three cases of bronchial hyalinizing clear cell carcinomas, confirmed by both fluorescence in situ hybridization (FISH) and RT-PCR, focusing on histologic and immunohistochemical characteristics in a comparison with three cases of salivary gland origin...
February 12, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29428807/the-imprint-of-salivary-secretion-in-autoimmune-disorders-and-related-pathological-conditions
#4
REVIEW
Kashi Raj Bhattarai, Raghupatil Junjappa, Mallikarjun Handigund, Hyung-Ryong Kim, Han-Jung Chae
Xerostomia is a state of oral dryness associated with salivary gland dysfunction and is induced by stress, radiation and chemical therapy, various systemic and autoimmune diseases, and specific medications. Fluid secretion is interrupted by the stimulation of neurotransmitter-induced increase in cytosolic calcium ([Ca 2+ ] i ) in salivary gland acinar cells, prompting the mobilization of ion channels and their transporters. Salivary fluid and protein secretion are principally dependent on parasympathetic and sympathetic nerves...
February 8, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29419396/expanding-primary-cells-from-mucoepidermoid-and-other-salivary-gland-neoplasms-for-genetic-and-chemosensitivity-testing
#5
Ahmad M Alamri, Xuefeng Liu, Jan K Blancato, Bassem R Haddad, Weisheng Wang, Xiaogang Zhong, Sujata Choudhary, Ewa Krawczyk, Bhaskar V Kallakury, Bruce J Davidson, Priscilla A Furth
Restricted availability of cell and animal models is a rate-limiting step for investigation of salivary gland neoplasm pathophysiology and therapeutic response. Conditionally reprogrammed cell (CRC) technology enables establishment of primary epithelial cell cultures from patient material. This study tested a translational workflow for acquisition, expansion and testing of CRC-derived primary cultures of salivary gland neoplasms from patients presenting to an academic surgical practice. Results showed that cultured cells were sufficient for epithelial cell-specific transcriptome characterization to detect candidate therapeutic pathways and fusion genes, and for screening for cancer risk-associated single nucleotide polymorphisms (SNPs) and driver gene mutations through exome sequencing...
January 29, 2018: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/29412748/characterization-of-salivary-gland-tumors-with-diffusion-tensor-imaging
#6
Ahmed Abdel Khalek Abdel Razek
PURPOSE: To characterize salivary glands tumors with diffusion tensor imaging. METHODS: This study was conducted upon 53 patients (aged 18-81 years: mean 37 years) with salivary gland tumors that underwent diffusion tensor imaging was obtained using a single-shot echo-planar imaging sequence with parallel imaging at 1.5 tesla scanner. Forty-eight slices were obtained, with a thickness of 2.5 mm, with no gap and the total scan duration was 7-8 min. The fractional anisotropy (FA) and the mean diffusivity (MD) value of the salivary gland tumors was calculated and correlated with pathological findings...
February 7, 2018: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29409471/pd-l1-expression-in-malignant-salivary-gland-tumors
#7
Koji Harada, Tarannum Ferdous, Yoshiya Ueyama
BACKGROUND: Programmed death-1 ligand-1 (PD-L1) an important cancer biomarker that can suppress the immune system and its high expression is often reported to be related with increased tumor aggressiveness in some cancers. Here, we examined and evaluated PD-L1 expression in patients with malignant salivary gland tumor. Moreover, the relationship between PD-L1 immunolocalization and clinical pathological features, as well as the prognosis of malignant salivary gland tumors was investigated...
February 6, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29399982/warthins-tumor-cyto-histological-spectrum-with-emphasis-on-diagnostic-difficulties
#8
Neelam Sood, Parismrita Borah
Warthins tumour is characterized by the presence of epithelial proliferation in a lymphoid stroma. It has been categorized as Sieferts types: 1-4, depending on the proportions of the 2 components. Although FNA is fairly accurate in establishing the diagnosis, the cytologic diagnosis of this tumor has potential sources of error. This retrospective study was conducted in the Department of Pathology and Lab Medicine, of a tertiary care hospital. Cytology and surgical pathology records of past 15 years were screened...
February 5, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29389040/validation-of-nomograms-for-overall-survival-cancer-specific-survival-and-recurrence-in-carcinoma-of-the-major-salivary-glands
#9
Ashley Hay, Jocelyn Migliacci, Daniella Karassawa Zanoni, Snehal Patel, Changhong Yu, Michael W Kattan, Ian Ganly
BACKGROUND: The purpose of this study was to investigate the performance of the Memorial Sloan Kettering Cancer Center salivary carcinoma nomograms predicting overall survival, cancer-specific survival, and recurrence with an external validation dataset. METHODS: The validation dataset comprised 123 patients treated between 2010 and 2015 at our institution. They were evaluated by assessing discrimination (concordance index [C-index]) and calibration (plotting predicted vs actual probabilities for quintiles)...
February 1, 2018: Head & Neck
https://www.readbyqxmd.com/read/29387612/expression-of-vascular-endothelial-cadherin-in-mucoepidermoid-carcinoma-role-in-cancer-development
#10
Soussan Irani, Arash Dehghan
Objectives: Mucoepidermoid carcinoma (MEC) accounts for 35% of all malignant salivary gland tumors. Previous investigations have shown that vasculogenic mimicry (VM) exists in many cancers which can be used as a prognostic factor of poor prognosis. Elevated expression level of vascular endothelial (VE)-cadherin has been implicated in cancer neovascularization, growth, and progression. The current study aimed to study the presence of VE-cadherin in VM channels and tumor cells in different grades of MEC...
November 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29387416/lacrimal-myoepithelial-carcinoma-ex-recurrent-pleomorphic-adenoma-a-clinicopathological-report-and-review-of-the-literature
#11
Noppadol Larbcharoensub, Duangjai Pangpunyakulchai, Rangsima Aroonroch, Lojana Tuntiyatorn, Pornchai Mahaisavariya
Myoepithelial carcinoma is an uncommon malignant tumor of the lacrimal gland, composed of neoplastic myoepithelial cells with an infiltrative growth. The present study describes a unique case of progressive proptosis and blindness of the right eye in a 68-year-old woman following total tumor removal for lacrimal pleomorphic adenoma. Clinical study, surgical exploration, and pathology revealed lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma, T2N0M0. In addition, 18 cases of lacrimal myoepithelial tumor that have been previously described in the literature are reviewed...
January 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29387196/decreased-microrna-181a-and-16-expression-levels-in-the-labial-salivary-glands-of-sj%C3%A3-gren-syndrome-patients
#12
Yuhua Wang, Guohua Zhang, Lingling Zhang, Miansong Zhao, Hongdong Huang
Sjögren syndrome (SS) is characterized by dysfunction of the exocrine glands, particularly the salivary and lacrimal glands. Thus, labial salivary gland biopsy is useful method for diagnosing SS. The aim of the present study was to investigate the microRNA (miRNA or miR) profile of labial salivary glands obtained from SS patients and to examine the correlation of miR-181a and -16 levels with the pathological grade in SS. miRNA expression in labial salivary gland tissues was profiled in 3 female patients with primary SS and 3 female patients with non-SS sicca syndrome using microarray analysis...
January 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29383488/-diagnostic-and-predictive-molecular-pathology-of-head-and-neck-neoplasms
#13
REVIEW
A Agaimy, W Weichert, F Haller, A Hartmann
As a result of some seminal observations as well as a consequence of increasing use of modern and innovative molecular diagnostic technologies, a variety of new genetic aberrations have been discovered in head and neck neoplasms of different anatomic locations and histogenetic origins. These advances resulted in the establishment of new molecularly defined disease entities. On the other hand, some of these new genetic biomarkers paved the way to potentially promising novel therapeutic opportunities. Diverse old (well known in other entities) and newly discovered translocations and gene fusions represent the leading subgroup of these genetic aberrations...
January 30, 2018: Der Pathologe
https://www.readbyqxmd.com/read/29376736/estimation-of-proton-density-fat-fraction-of-the-salivary-gland-among-various-pathological-conditions
#14
Toru Chikui, Yasuo Yamashita, Yoshitaka Kise, Tomonori Saito, Kazutoshi Okamura, Kazunori Yoshiura
OBJECTIVE: Our first objective was to prove the validity of the six-point Dixon method for estimating the proton density fat fraction (PDFF) of the salivary gland. The second objective was to estimate the salivary gland PDFF using Dixon method to evaluate the pathological conditions. METHODS: At first, 12 volunteers underwent two types of sequences: single-voxel MRS and the Dixon method and the PDFFs obtained by the two methods were compared. Next, a total of 67 individuals (normal, n=46; Sjögren's syndrome [SS], n=11; and IgG4-related dacryoadenitis and sialadenitis [IgG4-DS], n=4, parotitis, n=6) were enrolled to estimate the parotid gland (PG) and submandibular gland (SMG) PDFF using the Dixon method...
January 29, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29349817/anatomical-study-of-the-so-called-retromolar-gland-distinguishing-normal-anatomy-from-oral-cavity-pathology
#15
Joe Iwanaga, Ken Nakamura, Fernando Alonso, Christie Kirkpatrick, Rod J Oskouian, Koichi Watanabe, R Shane Tubbs
INTRODUCTION: The minor salivary glands in the retromolar trigone have rarely been studied. The aim of this study was to better define the anatomy of the minor salivary glands in the retromolar trigone and establish the relationships between these and adjacent structures. MATERIALS AND METHODS: The gland in the retromolar trigone was exposed and its relationships to surrounding structures were observed on twenty cadaveric sides. RESULTS: The boundaries of the gland included the superior pharyngeal constrictor muscle, the tendon of the buccinator muscle, and loose connective tissue...
January 19, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29337642/perineural-invasion-in-parotid-gland-malignancies
#16
Phillip Huyett, Umamaheswar Duvvuri, Robert L Ferris, Jonas T Johnson, Barry M Schaitkin, Seungwon Kim
Objectives To investigate the clinical predictors and survival implications of perineural invasion (PNI) in parotid gland malignancies. Study Design Case series with chart review. Setting Tertiary care medical center. Subjects and Methods Patients with parotid gland malignancies treated surgically from 2000 to 2015 were retrospectively identified in the Head and Neck Cancer Registry at a single institution. Data points were extracted from the medical record and original pathology reports. Results In total, 186 patients with parotid gland malignancies were identified with a mean follow-up of 5...
January 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29302287/evaluation-of-changes-in-salivary-composition-in-renal-failure-patients-before-and-after-hemodialysis
#17
Nishath Khanum, Mahesh Mysore-Shivalingu, Srisha Basappa, Archana Patil, Santosh Kanwar
Background: Saliva plays a major role in preserving the integrity of oral tissues. The oral health of renal failure patients could be negatively affected by the underlying pathology, the dialysis treatment, or an altered salivary composition. Major systemic changes occur during hemodialysis (HD), which could affect the flow rate and biochemical composition of saliva. Therefore, the aim of this study was to evaluate the effects of HD on the salivary flow rate, pH and biochemical composition before and after completion of a dialysis session...
November 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29297959/p2y2-r-deletion-ameliorates-sialadenitis-in-il-14%C3%AE-transgenic-mice
#18
Lucas T Woods, Jean M Camden, Mahmoud G Khalafalla, Michael J Petris, Laurie Erb, Julian L Ambrus, Gary A Weisman
OBJECTIVE: Interleukin-14α-transgenic (IL-14αTG) mice develop an autoimmune exocrinopathy with characteristics similar to Sjögren's syndrome, including sialadenitis and hyposalivation. The P2Y2 receptor (P2Y2 R) for extracellular ATP and UTP is upregulated during salivary gland inflammation (i.e., sialadenitis) where it regulates numerous inflammatory responses. The present study investigated the role of P2Y2 Rs in autoimmune sialadenitis in the IL-14αTG mouse model of Sjögren's syndrome...
January 3, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29284954/effect-of-transcutaneous-electrical-nerve-stimulation-on-parotid-saliva-flow-in-patients-with-hyposalivation
#19
P Venkatalakshmi Aparna, S Leena Sankari, M Deivanayagi, A Priyadharshini, C K Vishnupriya, B Niveditha
Context: In recent days, we have come across an increase incidence of dry mouth as a side effects of drugs and in order to bring an awareness about a simple non- invasive method to increase the salivary flow, we have used TENS which in many way is beneficial to patients with metabolic disorders. Aims and Objectives: The aim is to assess the effectiveness of transcutaneous electrical nerve stimulation on salivary gland function in patients with hyposalivation. Subjects and Methods: The present study included total of 25 subjects with complaint of hyposalivation...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29258258/galectins-and-carcinogenesis-their-role-in-head-and-neck-carcinomas-and-thyroid-carcinomas
#20
REVIEW
Nadège Kindt, Fabrice Journe, Ghanem E Ghanem, Sven Saussez
Head and neck cancers are among the most frequently occurring cancers worldwide. Of the molecular drivers described for these tumors, galectins play an important role via their interaction with several intracellular pathways. In this review, we will detail and discuss this role with specific reference to galectins-1, -3, and -7 in angiogenesis, cell proliferation, and invasion as well as in cell transformation and cancer progression. Furthermore, we will evaluate the prognostic value of galectin expression in head and neck cancers including those with oral cavity, salivary gland, and nasopharyngeal pathologies...
December 18, 2017: International Journal of Molecular Sciences
keyword
keyword
16773
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"