keyword
MENU ▼
Read by QxMD icon Read
search

Ovarial pathology

keyword
https://www.readbyqxmd.com/read/29349725/ki67-proliferative-index-in-carcinoid-tumors-involving-ovary
#1
Xiaotun Zhang, Andrea Jones, Sarah M Jenkins, Yajue Huang
Primary ovarian carcinoid tumors are rare neoplasms that constitute less than 0.1% of all ovarian carcinomas. However, carcinoid tumors metastatic to ovaries are more common. Cell proliferative rate is an important factor in the determination of neuroendocrine tumor prognosis. Limited data are available as regards Ki67 proliferation index in predicting the physiological features of carcinoid tumors involving the ovary. Pathology files of Mayo Clinic Rochester (1995-2014) were searched, and clinical information was collected from medical records...
January 18, 2018: Endocrine Pathology
https://www.readbyqxmd.com/read/29342266/causes-patterns-and-severity-of-androgen-excess-in-1205-consecutively-recruited-women
#2
Yasir S Elhassan, Jan Idkowiak, Karen Smith, Miriam Asia, Helena Gleeson, Rachel Webster, Wiebke Arlt, Michael W O'Reilly
Context: Androgen excess in women is predominantly due to underlying polycystic ovary syndrome (PCOS). However there is a lack of clarity regarding patterns and severity of androgen excess that should be considered predictive of non-PCOS pathology. Objective: We examined the diagnostic utility of simultaneous measurement of serum dehydroepiandrosterone sulfate (DHEAS), androstenedione (A4) and testosterone (T) to delineate biochemical signatures and cut-offs predictive of non-PCOS disorders in women with androgen excess...
January 12, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29321035/dhea-induced-ovarian-hyperfibrosis-is-mediated-by-tgf-%C3%AE-signaling-pathway
#3
Daojuan Wang, Wenqing Wang, Qiao Liang, Xuan He, Yanjie Xia, Shanmei Shen, Hongwei Wang, Qian Gao, Yong Wang
BACKGROUND: The polycystic ovary syndrome (PCOS) is a common metabolic and endocrine disorder with pathological mechanisms remain unclear. The following study investigates the ovarian hyperfibrosis forming via transforming growth factor-β (TGF-β) signaling pathway in Dehydroepiandrosterone (DHEA)- induced polycystic ovary syndrome (PCOS) rat model. We furthermore explored whether TGF-βRI inhibitor (SB431542) decreases ovarian fibrosis by counterbalancing the expression of fibrotic biomarkers...
January 10, 2018: Journal of Ovarian Research
https://www.readbyqxmd.com/read/29317075/the-origin-of-endometriosis-associated-ovarian-cancer-from-uterine-neoplastic-lesions
#4
Elisabetta Garavaglia, Cristina Sigismondi, Stefano Ferrari, Massimo Candiani
Endometriosis is a risk factor for type I epithelial ovarian cancer but an issue to be clarified is the site of origin of endometriosis associated ovarian cancer. Here we proposed that the uterus may be the organ of origin of ovarian endometrioid cancer associated with endometriosis. Thus, the first neoplastic transformation would characterize the uterine cells migrating in the pelvis via retrograde menstruation and they would implant secondarily on the ovary. Supporting this hypothesis, an higher incidence of synchronous precancerous and cancerous endometrial pathology in patients affected by ovarian endometrioid cancer associated with endometriosis was showed...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29316041/bilateral-tubo-ovarian-abscesses-presenting-with-huge-pelvic-mass-after-repeated-intrauterine-inseminations-in-a-woman-with-severe-endometriosis
#5
Patsama Vichinsartvichai
A 32-year-old woman consulted for an evaluation of pelvic pain following intrauterine insemination (IUI). Vaginal and abdominal sonography, septic workup were performed and laparoscopic surgery was scheduled after failure to respond to a course of antibiotics. During laparoscopic surgery, bilateral tubo-ovarian abscesses arising on the endometriotic cysts of both ovaries were identified with a vast amount of brownish peritoneal fluid under the adhesion of the greater omentum. Bilateral ovarian cystectomy, right salpingectomy and lysis adhesion were performed...
January 5, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29315627/transfusion-support-for-transgender-men-of-childbearing-age
#6
James A Mays, Dina N Greene, Ryan A Metcalf, Monica B Pagano
BACKGROUND: To date, limited attention has been given to transgender recipients of blood components, particularly transgender men of childbearing age. Here, we highlight the essential information needed to provide transfusion support for this population. CASE REPORT: A 40-year-old transgender man, who retained his uterus and ovaries, presented with severe vaginal hemorrhage following biopsies for a cervical mass. He was admitted to the Gynecology unit and emergency blood was ordered...
January 7, 2018: Transfusion
https://www.readbyqxmd.com/read/29310403/multilocular-cystic-leiomyoma-of-the-anterolateral-abdominal-wall-a-case-report-and-literature-review
#7
Kenji Yorita, Yu Tanaka, Koki Hirano, Michio Kuwahara, Kimiko Nakatani, Masaharu Fukunaga, Abbas Agaimy
RATIONALE: Leiomyomas arising from the anterolateral abdominal wall are uncommon, and their pathogenesis remains unknown. We present the 15th case of such a tumor, having this unique tumor morphology, followed by a detailed discussion on disease pathogenesis. PATIENT CONCERNS: A 48-year-old, asymptomatic perimenopausal, multiparous Japanese woman presented with a left-sided pelvic mass. She had no history of previous surgeries or uterine leiomyomas. Although a transabdominal ultrasonogram raised suspicions of an ovarian tumor, a transvaginal ultrasonogram confirmed normal ovaries...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29305268/long-term-estradiol-17%C3%AE-exposure-decreases-the-cholinergic-innervation-pattern-of-the-pig-ovary
#8
B Jana, K A Meller, M Czajkowska, J Całka
Elevated levels of endogenous estrogens in the course of pathological states of ovaries, as well as xenoestrogens, may lead to hyperestrogenism. It has previously been demonstrated that long-term estradiol-17β (E2) administration in adult gilts affected the population of sympathetic intraovarian nerve fibers. The aim of this study has been to determine the effect of long-term E2 exposure on the cholinergic innervation pattern of porcine ovaries. Intraovarian distribution and the density of nerve fibers immunoreactive (IR) to vesicular acetylocholine transporter (VAChT) and/or neuronal isoform of nitric oxide synthase (nNOS), vasoactive intestinal polypeptide (VIP), somatostatin (SOM) were determined...
January 2, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29304224/in-vitro-differentiation-of-human-oocyte-like-cells-from-oogonial-stem-cells-single-cell-isolation-and-molecular-characterization
#9
Erica Silvestris, Paola Cafforio, Stella D'Oronzo, Claudia Felici, Franco Silvestris, Giuseppe Loverro
STUDY QUESTION: Are the large cells derived from cultured DEAD box polypeptide 4 (DDX4)-positive oogonial stem cells (OSCs), isolated from the ovarian cortex of non-menopausal and menopausal women, oocyte-like cells? SUMMARY ANSWER: Under appropriate culture conditions, DDX4-positive OSCs from non-menopausal and menopausal women differentiate into large haploid oocyte-like cells expressing the major oocyte markers growth differentiation factor 9 (GDF-9) and synaptonemal complex protein 3 (SYCP3) and then enter meiosis...
January 3, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29299705/a-comparison-of-the-prognosis-between-adenocarcinoma-and-squamous-cell-carcinoma-in-stage-ib-iia-cervical-cancer
#10
Xiuzhen Xie, Kun Song, Baoxia Cui, Jie Jiang, Xingsheng Yang, Beihua Kong
OBJECTIVE: To explore differences in prognosis between adenocarcinoma (AC) and squamous cell carcinoma (SCC) and to explore feasibility of ovarian preservation in stage IB-IIA cervical cancer (CC). MATERIALS AND METHODS: Medical records of 810 patients (682 SCC + 128 AC) with stage IB-IIA CC were reviewed. Clinical and pathological characters of the two groups were compared using the chi-squared test. Kaplan-Meier survival analysis was used in univariate analysis of prognostic factors...
January 3, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29299127/adverse-stimulation-of-4-nonylphenol-in-abnormal-reproductive-organs-of-female-chickens
#11
Fenghua Zhang, Peng Yang, Lei Qin, Jie Zhang
4-Nonylphenol (4-NP) is a known endocrine disrupting chemical and a persistent environmental contaminant. However, the 4-NP caused mechanism of reproductive toxicity still remains largely unknown in birds. In this study, female chickens (Hy-Line Variety White) were dosed via oral gavage in the early laying period with 0, 50, 100, and 200 mg 4-NP/kg/d for 60 days. Food intake and weight increase were monitored in this organism to investigate chicken growth and development. Moreover, pathological changes of reproductive organs, serum hormone, and mRNA changes on the HPOA were detected...
December 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/29298536/improvement-of-hyperandrogenism-oligo-ovulation-and-ovarian-morphology-in-a-patient-with-polycystic-ovary-syndrome-possible-role-of-ovarian-wedge-resection
#12
YuanYuan Zhang, SuiYu Luo, ZhiQuan Gong, XiaoYa Feng, ZiYi Wang, HaoHui Zhu, Yu Wang
Polycystic ovary syndrome (PCOS) is an endocrinological abnormality which typically presents as hormones disorder and/or infertility. It has received more and more attention in recent years though its pathogenesis is still unclear. Ovarian mucinous adenoma is a rarely pathological type which generates from epithelial cell of ovary. Here we present a patient with PCOS and ovarian mucinous tumor (occasionally discovered by cesarean section) receiving a complete relief after benign ovarian tumor excision. In this case, tumor excision played as a partial resection of ovary which might result in the normalized concentration level of hormones and morphology of ovary...
January 3, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29275192/detection-of-aristaless-related-homeobox-protein-in-ovarian-sex-cord-stromal-tumors
#13
Tamara Knific, Snježana Frković Grazio, Tea Lanišnik Rižner
OBJECTIVE: To examine the potential of ARX as a novel biomarker of ovarian endometriosis and other ovarian pathologies. METHODS: The mRNA level of ARX in ovarian endometriosis and normal endometrium samples was determined by real-time PCR, while the protein level was determined by Western blotting and immunohistochemical staining. Immunohistochemical analysis was performed on nearly 200 tissue samples of different ovarian pathologies. GraphPad Prism was used for statistical analysis...
December 21, 2017: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/29260365/prognostic-importance-of-peritoneal-lesion-to-primary-tumour-standardized-uptake-value-ratio-in-advanced-serous-epithelial-ovarian-cancer
#14
Hyun Hoon Chung, Jae-Weon Kim, Noh-Hyun Park, Yong Sang Song, Gi Jeong Cheon
OBJECTIVES: Using preoperative PET/CT, we evaluated the prognostic value of preoperative [18F]FDG uptake ratio between various metastatic lesions and primary tumour in patients with advanced serous epithelial ovarian cancer (EOC). METHODS: We retrospectively reviewed patients with International Federation of Gynecology and Obstetrics (FIGO) stage III, IV serous EOC who underwent preoperative [18F]FDG PET/CT scans. Clinico-pathological variables and PET/CT parameters such as maximum standardized uptake value of the ovarian cancer (SUVovary), pelvic or para-aortic LN (SUVLN), peritoneal (SUVperit) and distant extra-peritoneal (SUVdist) metastatic lesions, and the metastatic lesion-to-ovarian cancer standardized uptake value ratio were assessed...
December 19, 2017: European Radiology
https://www.readbyqxmd.com/read/29258842/pathological-analysis-of-silkworm-infected-by-two-microsporidia-nosema-bombycis-cq1-and-vairimorpha-necatrix-bm
#15
Xian-Zhi Meng, Bo Luo, Xiang-You Tang, Qiang He, Ting-Rong Xiong, Zhuo-Ya Fang, Guoqing Pan, Tian Li, Ze-Yang Zhou
Microsporidia Nosema bombycis CQ1 can be vertically transmitted in silkworm Bombyx mori but Vairimorpha necatrix BM cannot. Therefore, the pathological differences in silkworm infected with these two microsporidia required clarification. Here, we compared the virulence of N. bombycis CQ1 and V. necatrix BM against silkworm. The pathological characteristics in intestine, testis and ovary were surveyed using paraffin sections, scanning electron microscopy and transmission electron microscopy. Our data firstly showed that the virulence of V...
December 16, 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/29258619/effects-of-low-intensity-pulsed-ultrasound-lipus-pretreated-human-amnion-derived-mesenchymal-stem-cell-had-msc-transplantation-on-primary-ovarian-insufficiency-in-rats
#16
Li Ling, Xiushan Feng, Tianqin Wei, Yan Wang, Yaping Wang, Wenqian Zhang, Lianli He, Ziling Wang, Qianru Zeng, Zhengai Xiong
BACKGROUND: Human amnion-derived mesenchymal stem cells (hAD-MSCs) have the features of mesenchymal stem cells (MSCs). Low-intensity pulsed ultrasound (LIPUS) can promote the expression of various growth factors and anti-inflammatory molecules that are necessary to keep the follicle growing and to reduce granulosa cell (GC) apoptosis in the ovary. This study aims to explore the effects of LIPUS-pretreated hAD-MSC transplantation on chemotherapy-induced primary ovarian insufficiency (POI) in rats...
December 19, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29242280/results-of-fertility-sparing-surgery-for-expansile-and-infiltrative-mucinous-ovarian-cancers
#17
Sebastien Gouy, Marine Saidani, Amandine Maulard, Slim Bach-Hamba, Enrica Bentivegna, Alexandra Leary, Patricia Pautier, Mojgan Devouassoux-Shisheboran, Catherine Genestie, Philippe Morice
BACKGROUND: No series had been reported focusing on the results of fertility-sparing surgery in stage I mucinous ovarian cancers according to histotype (infiltrative vs. expansile). Investigating such outcomes was the aim of the present study. MATERIALS AND METHODS: The present study was a retrospective analysis of patients treated conservatively with preservation of the uterus and contralateral ovary from 1976 to 2016. The pathology of the tumors was reviewed by two expert pathologists according to the 2014 World Health Organization (WHO) classification criteria...
December 14, 2017: Oncologist
https://www.readbyqxmd.com/read/29241974/endometriosis-associated-ovarian-neoplasia
#18
REVIEW
Xavier Matias-Guiu, Colin J R Stewart
This article reviews the most relevant pathological and molecular features of ovarian tumours that are associated with endometriosis. Endometriosis is a common condition, affecting 5-15% of all women, and it has been estimated that 0.5-1% of cases are complicated by neoplasia. The most common malignant tumours in this setting are endometrioid adenocarcinoma and clear cell adenocarcinoma, each accounting for approximately 10% of ovarian carcinomas in Western countries. A minority of cases are associated with Lynch syndrome...
December 11, 2017: Pathology
https://www.readbyqxmd.com/read/29232468/the-new-classifications-of-ovarian-fallopian-tube-and-primary-peritoneal-cancer-and-their-clinical-implications
#19
L R Duska, E C Kohn
The roles of histologic characterization and staging are to provide reproducible metrics for cancer classification with which to direct the most appropriate clinical care and to yield the most stable reliable system to allow both prospective and retrospective data analysis. Both the histologic and staging classifications of malignant ovarian/tubal/peritoneal cancers have recently changed. The World Health Organization sponsored a review and reclassification of the pathology of cancers of the ovaries, fallopian tubes, and peritoneum, and published these updates in 2014...
November 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29230555/non-visualization-of-the-ovary-on-ct-or-ultrasound-in-the-ed-setting-utility-of-immediate-follow-up-imaging
#20
Elena Motuzko, Maria Solis, Moazzem Kazi, Ron Gefen
PURPOSE: In the setting of female patients in the ED receiving both a CT scan and ultrasound of the pelvis, we compared the studies to assess the diagnostic value of non-visualization of the ovary in predicting the absence of ovarian disease. METHODS: A retrospective review of the electronic medical record identified adult female non-pregnant patients who received both a CT abdomen and pelvis and a transabdominal and transvaginal pelvic ultrasound within a 48-h period through the emergency department...
December 11, 2017: Abdominal Radiology
keyword
keyword
16772
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"