Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Menno R Germans, Maud A Tjerkstra, René Post, Amy Brenner, Mervyn DI Vergouwen, Gabriël Je Rinkel, Yvo Bwem Roos, René van den Berg, Bert A Coert, W Peter Vandertop, Dagmar Verbaan
INTRODUCTION: The ULTRA-trial investigated effectiveness of ultra-early administration of tranexamic acid (TXA) in subarachnoid hemorrhage (SAH) and showed that TXA reduces the risk of rebleeding without concurrent improvement in clinical outcome. Previous trials in bleeding conditions, distinct from SAH, have shown that time to start of antifibrinolytic treatment influences outcome. This post-hoc analysis of the ULTRA-trial investigates whether the interval between hemorrhage and start of TXA impacts the effect of TXA on rebleeding and functional outcome following aneurysmal SAH...
April 12, 2024: European Stroke Journal
#2
JOURNAL ARTICLE
Yan Su, Yonggui Cao, Haoran Zang, Wuzhou Gao, Xuewu Liu, Fuqing Li, Qingming An, Zhicheng Dai
OBJECTIVE: To investigate the early prediction value of transcranial Doppler ultrasound (TCD) combined with serum melatonin level for delayed cerebral ischemia (DCI) caused by subarachnoid hemorrhage (SAH). METHODS: This paper is a prospective study. A total of 120 patients with SAH treated were included. The patients were divided into the DCI group (40 cases) and non-DCI group (80 cases) according to whether DCI occurred 14 days after SAH (DCI usually occurs 4 to 14 d after bleeding)...
April 11, 2024: Neurologist
#3
JOURNAL ARTICLE
Xinzhu Bai, Jinhui He, Songsong Lu, Chun Li, Yilin Wang, Jian Xiong
With the development of modern medical standards, autoimmune diseases and their associated successive osteoporosis have received increasing attention in recent years. Patients with autoimmune diseases, due to the characteristics of the disease and the prolonged use of glucocorticoid hormone therapy, may affect the bone formation and bone absorption of the patient, followed by severe successive osteoporosis, thereby increasing the risk of osteoporotic vertebral fractures. Vertebral compression fractures of the spine are common fracture types in patients with osteoporotic fractures...
April 18, 2024: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
#4
JOURNAL ARTICLE
Aysha Gomaa, Chemindra Biyanwila, Mansi Jantre
A previously healthy man in his 60s presents with a one-day history of insidious onset headache and 'walking into doors'. He reported transient right arm pain and tingling but no weakness. A CT brain showed a right middle cerebral artery (MCA) infarct as well as a synchronous right frontal lobe convexal subarachnoid haemorrhage (cSAH). An arch to vertex CT angiogram demonstrated right MCA occlusion and complete right internal carotid artery (ICA) occlusion from its origin. Reconstitution of flow was seen within the distal right ICA at the level of the distal foramen lacerum...
April 8, 2024: BMJ Case Reports
#5
JOURNAL ARTICLE
Ping Hu, Yanze Wu, Tengfeng Yan, Lei Shu, Feng Liu, Bing Xiao, Minhua Ye, Miaojing Wu, Shigang Lv, Xingen Zhu
OBJECTIVE: The relationships between immediate bleeding severity, postoperative complications, and long-term functional outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH) remain uncertain. Here, the authors apply their recently developed automated deep learning technique to quantify total bleeding volume (TBV) in patients with aSAH and investigate associations between quantitative TBV and secondary complications, adverse long-term functional outcomes, and death. METHODS: Electronic health record data were extracted for adult patients admitted to a single institution within 72 hours of aSAH onset between 2018 and 2021...
March 29, 2024: Journal of Neurosurgery
#6
JOURNAL ARTICLE
Gayathri M Sivagurunathan, Dimitrios Fotopoulos
Introduction Reversible cerebral vasoconstriction syndrome (RCVS) is most commonly characterized by focal or diffuse severe thunderclap headache with or without focal neurological deficits and associated transient focal vasoconstriction of the intracerebral arteries lasting up to three months. We present six patients diagnosed as RCVS, with three patients presenting with focal neurological deficits without headache and the remaining three with severe headache alone. Neuroimaging revealed focal subarachnoid bleed with or without segmental intracerebral vasospasm, which resolved over three months...
February 2024: Curēus
#7
Narutada Ando, Yusuke Nakazawa, Takeshi Miyata, Takenori Ogura, Wataru Shiraishi, Taketo Hatano
Superficial siderosis is a disease in which hemosiderin is deposited under the leptomeninges and subpial layers of hindbrain structures, e.g., the cerebellum, brainstem, and eighth cranial nerve. The main symptoms of superficial siderosis are cerebellar ataxia, hearing loss, cognitive decline, and myelopathy. The activities of daily living of patients with superficial siderosis are severely impaired due to the progressive symptoms. Here, we report a patient with superficial siderosis whose symptoms deteriorated after lumbar subarachnoid-peritoneal (L-P) shunt surgery...
February 2024: Curēus
#8
JOURNAL ARTICLE
Congzhi Yan, Yun Li
Subarachnoid hemorrhage (SAH) is a neurological emergency that can lead to fatal outcomes. It occurs when bleeding happens in the subarachnoid space, a small gap between the arachnoid and pia mater. This condition results from the rupture of diseased or damaged blood vessels at the brain's base or surface. This study combined various omics approaches with Mendelian randomization analysis, including MR-IVW, MR Egger, MR weight median, and MR weight mode, to generate preliminary results. It also employed reverse Mendelian randomization, treating SAH as the exposure...
March 25, 2024: Molecular Neurobiology
#9
JOURNAL ARTICLE
Josef Finsterer
How to cite this article: Finsterer J. Transient Locked-in Syndrome after Aneurysmal Subarachnoid Bleeding due to Spasm Hypoxemia? Indian J Crit Care Med 2024;28(1):86.
January 2024: Indian Journal of Critical Care Medicine
#10
JOURNAL ARTICLE
Martina Glavan, Ana Jelic, Damien Levard, Juhana Frösen, Sara Keränen, Bart A A Franx, Ana-Rita Bras, Estelle R Louet, Ádám Dénes, Mario Merlini, Denis Vivien, Marina Rubio
Intracerebral aneurysms (IAs) are pathological dilatations of cerebral arteries whose rupture leads to subarachnoid hemorrhage, a significant cause of disability and death. Inflammation is recognized as a critical contributor to the formation, growth, and rupture of IAs; however, its precise actors have not yet been fully elucidated. Here, we report CNS-associated macrophages (CAMs), also known as border-associated macrophages, as one of the key players in IA pathogenesis, acting as critical mediators of inflammatory processes related to IA ruptures...
March 18, 2024: Acta Neuropathologica Communications
#11
Indira Acharya, Scott R DeBoer, Christopher J Haas
Tissue plasminogen activator (TPA) is indicated as an empiric therapy for refractory out-of-the-hospital cardiac arrest for suspected pulmonary embolism and myocardial infarction. Intracranial hemorrhage following TPA administration is a rare complication resulting in increased morbidity and mortality. A history of intracranial bleed, oral anticoagulant use prior to hospital admission, low body weight, and unstable hypertension with blood pressure above 180/110 mmHg at the time of presentation are associated with intracranial bleeding following tPA administration...
2024: Journal of Community Hospital Internal Medicine Perspectives
#12
JOURNAL ARTICLE
Manoj Kumar Nayak, Biswamohan Mishra, Sebastian Levejoseph, Ajay Garg, Kalyan Sarma, Biswajit Sahoo, Manjari Tripathi, Shailesh B Gaikwad
OBJECTIVES: Neural crest cells (NCCs) are transient structures in the fetal life in vertebrates, which develop at the junctional site of the non-neural and neural ectoderm, sharing a common developmental origin for diverse diseases. After Epithelio-mesenchymal (EMT) of the NCCs within the neural tube, delamination of NCCs occurs. After delamination, the transformation of these cells into various cell lineages produces melanocytes, bones, and cartilage of the skull, cells of the enteric and peripheral nervous system...
2024: Journal of Clinical Imaging Science
#13
JOURNAL ARTICLE
Munehiro Demura, Yasuo Sasagawa, Yasuhiko Hayashi, Osamu Tachibana, Mitsutoshi Nakada
BACKGROUND: Pituitary adenomas show typical visual field defects that begin superiorly and progress inferiorly. The cause of atypical visual field defects that start inferiorly remains unclear. This study aimed to understand this phenomenon using magnetic resonance imaging (MRI). METHODS: A total of 220 patients with pituitary adenomas underwent a visual field assessment of both eyes. Preoperative visual fields were assessed and classified into two types: superior quadrantanopia (typical) and inferior quadrantanopia (atypical)...
2024: Surgical Neurology International
#14
JOURNAL ARTICLE
Subhajit Hazra, Preet Amol Singh, Neha Bajwa
Warfarin is a popular anticoagulant with high global demand. However, studies have underlined serious safety issues when warfarin is consumed concomitantly with herbs or its formulations. This review aimed to highlight the mechanisms behind herb-warfarin interactions while laying special emphasis on its PKPD interactions and evidence on Herb-Warfarin Interaction (HWI) with regards to three different scenarios, such as when warfarin is consumed with herbs taken as foods or prescribed as medicine, or when used in special situations...
March 8, 2024: Current Drug Metabolism
#15
REVIEW
Yi Zhang, Chunyan Lei, Xi Huang, Meixia Zhang
Terson syndrome refers to intraocular haemorrhage that occurs due to subarachnoid bleeding associated with an acute increase in intracranial pressure. No previous study has reported a delayed macular hole (MH) secondary to Terson syndrome. A 17-year-old boy visited our department and presented with vitreous bleeding and a history of subarachnoid haemorrhage. Sub-internal limiting membrane (ILM) haemorrhage with ILM detachment and intraretinal haemorrhage were detected during pars plana vitrectomy. Additionally, a delayed MH was detected 1 week after the surgery...
March 2024: Journal of International Medical Research
#16
Junya Tatezuki, Sujong Pak, Fukutaro Ohgaki, Yasunori Takemoto, Yasuhiko Mochimatsu
Hemorrhagic changes in a dural arteriovenous fistula are typically associated with cortical venous reflux and occur as intracerebral or subarachnoid hemorrhages. A convexity dural arteriovenous fistula (DAVF) usually flows directly into the cortical veins and exhibits cortical venous reflux. Herein, we report a rare case of a convexity DAVF without cortical venous reflux presenting with a pure acute subdural hematoma. A 19-year-old man complaining of headache without any history of head injury was diagnosed with a left acute subdural hematoma on magnetic resonance imaging (MRI) and referred to our hospital...
2024: NMC Case Report Journal
#17
JOURNAL ARTICLE
Essi Raatikainen, Heikki Kiiski, Anne Kuitunen, Eija Junttila, Heini Huhtala, Antti Kallonen, Marika Ala-Peijari, Jaakko Långsjö, Johanna Saukkonen, Timo Valo, Terhi Kauppila, Sanni Raerinne, Juhana Frösen, Annukka Vahtera
BACKGROUND AND PURPOSE: Patients with aneurysmal subarachnoid hemorrhage (aSAH) have demonstrated increased blood coagulation which is thought to contribute to delayed cerebral ischemia (DCI) and to a worse outcome. Therefore, we sought to determine whether this increased blood coagulation, detectable with rotational thromboelastometry (ROTEM), was associated with DCI and neurological outcome. METHODS: We conducted a prospective observational study of 60 consecutive adult aSAH patients...
March 15, 2024: Journal of the Neurological Sciences
#18
Mateo Zuluaga-Gomez, Daniela Giraldo-Campillo, Daniel González-Arroyave, Robinson A Orjuela-Correa, Manuela Bedoya-Ortiz, Carlos M Ardila
Projectile embolism resulting from firearm injuries is a rare but highly lethal complication when not diagnosed early. This report presents a case of projectile embolism from a firearm injury with an unusual entry site, the cerebral venous circulation, which subsequently migrates to the pulmonary circulation with a fatal outcome. A 24-year-old male patient was admitted to a high-complexity hospital due to a gunshot wound. A plain skull computed tomography (CT) revealed a left laminar subdural hematoma and traumatic subarachnoid hemorrhage with multiple metallic fragments embedded in the skull, some penetrating the galeal sinus, with perilesional bleeding...
January 2024: Curēus
#19
JOURNAL ARTICLE
Noah L A Nawabi, John L Kilgallon, Jack J McNulty, Brittany M Stopa, Jakob V E Gerstl, Timothy R Smith
BACKGROUND AND OBJECTIVES: Traumatic subarachnoid hemorrhage (tSAH) is a common consequence of head trauma. Treatment of tSAH patients commonly involves serial CT imaging to assess for expansile hemorrhage. However, growing evidence suggests that these patients rarely deteriorate or require neurosurgical intervention. We assessed the utility of repeat CT imaging in adult patients with isolated tSAH and an intact initial neurologic exam. METHODS: Patients presenting to Mass General Brigham Hospitals with tSAH between 2000 and 2021 were eligible for inclusion in this retrospective cohort study...
February 23, 2024: World Neurosurgery
#20
JOURNAL ARTICLE
Anass Benomar, Jose Danilo B Diestro, Houssam Darabid, Karim Saydy, Lora Tzaneva, Jimmy Li, Eleyine Zarour, William Tanguay, Nohad El Sayed, Igor Gomes Padilha, Laurent Létourneau-Guillon, Céline Bard, Kristoff Nelson, Alain Weill, Daniel Roy, Johanna Eneling, William Boisseau, Thanh N Nguyen, Mohamad Abdalkader, Ahmed A Najjar, Ahmad Nehme, Émile Lemoine, Gregory Jacquin, David Bergeron, Tristan Brunette-Clément, Chiraz Chaalala, Michel W Bojanowski, Moujahed Labidi, Roland Jabre, Katrina H D Ignacio, Abdelsimar T Omar, David Volders, Adam A Dmytriw, Jean-François Hak, Géraud Forestier, Quentin Holay, Richard Olatunji, Ibrahim Alhabli, Lorena Nico, Jai J S Shankar, Adrien Guenego, Jose L R Pascual, Thomas R Marotta, Juan I Errázuriz, Amy W Lin, Aderaldo Costa Alves, Robert Fahed, Christine Hawkes, Hubert Lee, Elsa Magro, Lila Sheikhi, Tim E Darsaut, Jean Raymond
BACKGROUND AND PURPOSE: To evaluate the reliability and accuracy of nonaneurysmal perimesencephalic subarachnoid hemorrhage (NAPSAH) on Noncontrast Head CT (NCCT) between numerous raters. MATERIALS AND METHODS: 45 NCCT of adult patients with SAH who also had a catheter angiography (CA) were independently evaluated by 48 diverse raters; 45 raters performed a second assessment one month later. For each case, raters were asked: 1) whether they judged the bleeding pattern to be perimesencephalic; 2) whether there was blood anterior to brainstem; 3) complete filling of the anterior interhemispheric fissure (AIF); 4) extension to the lateral part of the sylvian fissure (LSF); 5) frank intraventricular hemorrhage; 6) whether in the hypothetical presence of a negative CT angiogram they would still recommend CA...
February 20, 2024: Journal of Neuroradiology. Journal de Neuroradiologie
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
