Matthew O Wiens, Jeffrey N Bone, Elias Kumbakumba, Stephen Businge, Abner Tagoola, Sheila Oyella Sherine, Emmanuel Byaruhanga, Edward Ssemwanga, Celestine Barigye, Jesca Nsungwa, Charles Olaro, J Mark Ansermino, Niranjan Kissoon, Joel Singer, Charles P Larson, Pascal M Lavoie, Dustin Dunsmuir, Peter P Moschovis, Stefanie Novakowski, Clare Komugisha, Mellon Tayebwa, Douglas Mwesigwa, Cherri Zhang, Martina Knappett, Nicholas West, Vuong Nguyen, Nathan Kenya Mugisha, Jerome Kabakyenga
BACKGROUND: Substantial mortality occurs after hospital discharge in children younger than 5 years with suspected sepsis, especially in low-income countries. A better understanding of its epidemiology is needed for effective interventions to reduce child mortality in these countries. We evaluated risk factors for death after discharge in children admitted to hospital for suspected sepsis in Uganda, and assessed how these differed by age, time of death, and location of death. METHODS: In this prospective, multisite, observational cohort study, we recruited and consecutively enrolled children aged 0-60 months admitted with suspected sepsis from the community to the paediatric wards of six Ugandan hospitals...
May 11, 2023: Lancet Child & Adolescent Health