keyword
MENU ▼
Read by QxMD icon Read
search

Ovary

keyword
https://www.readbyqxmd.com/read/29045292/ovarian-metastases-of-breast-cancers-with-signet-ring-cells-a-report-of-17-cases-including-14-krukenberg-tumors
#1
Jennifer A Bennett, Robert H Young, Ai-Ying Chuang, Melinda F Lerwill
Krukenberg tumor, defined as metastatic adenocarcinoma to the ovary containing at least 10% signet ring cells, usually arises from the stomach but can also originate from other sites. We reviewed 17 metastatic breast carcinomas to the ovary with signet ring cells to potentially identify features indicative of mammary origin as opposed to other possible primary sites. The patients ranged from 41 to 76 (mean, 53.6) yr. Fourteen had a prior history of invasive breast carcinoma (invasive ductal carcinoma, 4; invasive lobular carcinoma, 3; adenocarcinoma not otherwise specified, 3; carcinoma with ductal and lobular features, 2; and unspecified carcinoma, 2) and metastases were identified 2 to 284 (mean, 79) mo after the original diagnosis...
October 17, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29044994/characterization-and-expression-pattern-of-r-spondin1-in-cynoglossus-semilaevis
#2
Hailong Li, Wenteng Xu, Ying Zhu, Ning Zhang, Jialu Ma, Ai Sun, Zhongkai Cui, Fengtao Gao, Na Wang, Changwei Shao, Zhongdian Dong, Yangzhen Li
r-spondin1 (rspo1) encodes a secreted protein that is involved in the determination and differentiation of the mammalian ovary. However, little information is yet available for teleosts. Here, we identified a homologue of rspo1 in Cynoglossus semilaevis. The full-length cDNA of rspo1 had a length of 2,703 bp with an open reading frame of 834 bp, encoding a protein with a length of 277 amino-acids. rspo1 expression was detected via qRT-PCR in various tissues, and significant sexually dimorphic expression was observed in the gonads...
October 17, 2017: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/29044581/women-with-polycystic-ovary-syndrome-demonstrate-worsening-markers-of-cardiovascular-risk-over-the-short-term-despite-declining-hyperandrogenaemia-results-of-a-longitudinal-study-with-community-controls
#3
Heather G Huddleston, Molly M Quinn, Chia-Ning Kao, Nikolaus Lenhart, Mitchell P Rosen, Marcelle I Cedars
OBJECTIVE: To compare age-associated changes in cardiovascular risk markers in lean and obese reproductive-aged women with polycystic ovary syndrome (PCOS) with community controls DESIGN: Longitudinal study at an academic medical centre. PATIENTS: Patients diagnosed with PCOS by 2004 Rotterdam criteria in a multi-disciplinary clinic were systematically enrolled from 2006-2014 in a PCOS cohort study and subsequently agreed to participate in a longitudinal study. The comparison controls were from the prospective, longitudinal Ovarian Aging (OVA) study, which consists of healthy women with regular menstrual cycles recruited from 2006 to 2011...
October 16, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29044428/expression-of-stra8-is-conserved-in-therian-mammals-but-expression-of-cyp26b1-differs-between-marsupials-and-mice
#4
Danielle E Hickford, Siew Fen Lisa Wong, Stephen R Frankenberg, Geoff Shaw, Hongshi Yu, Keng Yih Chew, Marilyn B Renfree
The first sign of mammalian germ cell sexual differentiation is the initiation of meiosis in females and of mitotic arrest in males. In the mouse, retinoic acid induces ovarian Stra8 expression and entry of germ cells into meiosis. In developing mouse testes, cytochrome P450 family 26, subfamily b, polypeptide 1 (CYP26B1) produced by the Sertoli cells degrades retinoic acid, preventing Stimulated by Retinoic Acid Gene 8 (Stra8), expression and inhibiting meiosis. However, in developing humans, there is no evidence that CYP26B1 acts a meiosis-inhibiting factor...
August 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29044421/heterogeneous-hcg-and-hmg-commercial-preparations-result-in-different-intracellular-signalling-but-induce-a-similar-long-term-progesterone-response-in-vitro
#5
Laura Riccetti, Danièle Klett, Mohammed Akli Ayoub, Thomas Boulo, Elisa Pignatti, Simonetta Tagliavini, Manuela Varani, Tommaso Trenti, Alessia Nicoli, Francesco Capodanno, Giovanni Battista La Sala, Eric Reiter, Manuela Simoni, Livio Casarini
STUDY QUESTION: Are four urinary hCG/menotropin (hMG) and one recombinant preparation characterized by different molecular features and do they mediate specific intracellular signaling and steroidogenesis? SUMMARY ANSWER: hCG and hMG preparations have heterogeneous compositions and mediate preparation-specific cell signaling and early steroidogenesis, although similar progesterone plateau levels are achieved in 24 h-treated human primary granulosa cells in vitro...
October 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29044042/experimental-inoculation-of-oriental-river-prawn-macrobrachium-nipponense-with-white-spot-syndrome-virus-wssv
#6
Caiyuan Zhao, Hongtuo Fu, Shengming Sun, Hui Qiao, Wenyi Zhang, Shubo Jin, Sufei Jiang, Yiwei Xiong, Yongsheng Gong
The oriental river prawn Macrobrachium nipponense is an economically important species that is widely farmed in China. White spot syndrome virus (WSSV) is one of the most devastating pathogens of the cultured shrimp Litopenaeus vannamei, responsible for massive loss of its commercial products worldwide. We investigated the infectivity and pathogenicity of WSSV in adult M. nipponense using standardized conditions for L. vannamei. The median lethal dose of WSSV in adult M. nipponense was 103.84±0.06 copies g-1, which was about 1000-fold higher than in L...
October 18, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/29043708/comparison-of-in-vitro-fertilization-intracytoplasmic-sperm-injection-cycle-outcome-in-patients-with-and-without-polycystic-ovary-syndrome-a-modified-poisson-regression-model
#7
Amir Almasi-Hashiani, Mohammad Ali Mansournia, Mahdi Sepidarkish, Samira Vesali, Azadeh Ghaheri, Arezoo Esmailzadeh, Reza Omani-Samani
Background: Polycystic ovary syndrome (PCOS) is a frequent condition in reproductive age women with a prevalence rate of 5-10%. This study intends to determine the relationship between PCOS and the outcome of assisted reproductive treatment (ART) in Tehran, Iran. MATERIALS AND METHODS: In this historical cohort study, we included 996 infertile women who referred to Royan Institute (Tehran, Iran) between January 2012 and December 2013. PCOS, as the main variable, and other potential confounder variables were gathered...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29043706/the-effects-of-exercise-on-expression-of-cyp19-and-star-mrna-in-steroid-induced-polycystic-ovaries-of-female-rats
#8
Fatemeh Aghaie, Homayoun Khazali, Mehdi Hedayati, Ali Akbarnejad
Background: Polycystic ovarian syndrome (PCOS) is the most frequent female endocrine disorder that affects 5-10% of women. PCOS is characterized by hyperandrogenism, oligo-/anovulation, and polycystic ovaries. The aim of the present research is to evaluate the expression of steroidogenic acute regulatory protein (StAR) and aromatase (CYP19) mRNA in the ovaries of an estradiol valerate (EV)-induced PCOS rat model, and the effect of treadmill and running wheel (voluntary) exercise on these parameters...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29043701/royal-jelly-promotes-ovarian-follicles-growth-and-increases-steroid-hormones-in-immature-rats
#9
Elham Ghanbari, Mohammad Rasool Khazaei, Mozafar Khazaei, Vahid Nejati
Background: Royal jelly (RJ) is a complementary diet widely prescribed by traditional medicine specialists for treatment of infertility. The aim of present study was to evaluate the effects of RJ on a set of reproductive parameters in immature female rats. MATERIALS AND METHODS: In this experimental study, thirty two immature female rats (30-35 g) were divided into four groups (n=8/group): three experimental groups and one control. The experimental groups received 100, 200 and 400 mg/kg/body weight doses of RJ daily for 14 days, and the control group received 0...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29043522/cryovial-monolayer-vitrification-for-ovarian-tissue-cryopreservation
#10
Hongxia Li, Haixia Cao, Xingping Guo, Huaixiu Wang
The cryopreservation of ovarian tissue has been proved to be effective for fertility preservation. To find a better cryopreservation method, we tested the efficacy of cryovial monolayer vitrification method in comparison with that of needle immersed vitrification (NIV). Ovaries from 10 female kunming mice aged 6-8 weeks were cut into pieces and allocated into group A (cryovial monolayer vitrification method), group B (NIV method) and group C (fresh control). In group A, pieces of ovarian tissue were layered around the inner wall of cryovial as a monolayer; and in group B, pieces of ovarian tissue were pierced with a needle...
October 17, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/29042633/catsper1-promoter-is-bidirectional-and-regulates-the-expression-of-a-novel-lncrna
#11
Salma E Jiménez-Badillo, Norma Oviedo, Christian Hernández-Guzmán, Lorenza González-Mariscal, Javier Hernández-Sánchez
The Catsper1 gene, whose expression is restricted to male germ cells, has great importance in reproductive biology because of its function in sperm motility and fertilization. We previously reported that the promoter of this gene has transcriptional activity in either direction in a heterologous system. In the present study, we found that the Catsper1 promoter has in vitro transcriptional activity in either orientation in GC-1 spg mouse spermatogonial cells. The results also showed that this promoter regulates the expression of a new divergent Catsper1 gene named Catsper1au (Catsper1 antisense upstream transcript)...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29042448/myo-inositol-effects-in-women-with-pcos-a-meta-analysis-of-randomized-controlled-trials
#12
Vittorio Unfer, Fabio Facchinetti, Beatrice Orrù, Barbara Giordani, John Nestler
Myo-inositol (MI) supplementation in women with polycystic ovary syndrome (PCOS) has been evaluated over the last years. Many hormonal and reproductive impairments associated with this disorder seem relieved by the supplement. The objective of the meta-analysis was to assess the effects of MI alone or combined with d-chiro-inositol (DCI) on the endocrine and metabolic abnormalities of women with PCOS. Literature was retrieved from selected databases, MEDLINE, EMBASE, PubMed and Research Gate (up to November 2016)...
November 2017: Endocrine Connections
https://www.readbyqxmd.com/read/29042436/wilms-tumor-protein-dependent-transcription-of-vegf-receptor-2-and-hypoxia-regulate-expression-of-the-testis-promoting-gene-sox9-in-murine-embryonic-gonads
#13
Karin M Kirschner, Lina K Sciesielski, Katharina Krueger, Holger Scholz
The Wilms tumor protein 1 (WT1) has been implicated in the control of several genes in sexual development, but its function in gonad formation is still unclear. Here, we report that WT1 stimulates expression of Kdr, the gene encoding VEGF receptor 2, in murine embryonic gonads. We found that WT1 and KDR are co-expressed in Sertoli cells of the testes and somatic cells of embryonic ovaries. Vivo-morpholino-mediated WT1 knockdown decreased Kdr transcripts in cultured embryonic gonads at multiple developmental stages...
October 17, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29042199/temporal-expression-and-gonadotropic-regulation-of-aromatase-and-estrogen-receptors-in-the-ovary-of-wall-lizard-hemidactylus-flaviviridis-correlation-with-plasma-estradiol-and-ovarian-follicular-development
#14
Mamta Tripathy, Umesh Rai
The current study in Indian wall lizard Hemidactylus flaviviridis for the first time demonstrates the reproductive phase-dependent expression pattern of aromatase (cyp19) and estrogen receptor subtypes (er-α and er-β) as well as their gonadotropic regulation in the ovary of a squamate. The expression of cyp19 remained low during regressed phase, increased markedly in recrudescent and declined sharply in breeding phase. Further, temporal profile of plasma estradiol 17-β (E2) was found to be relatively parallel to the expression pattern of ovarian cyp19...
October 14, 2017: Steroids
https://www.readbyqxmd.com/read/29040530/the-prevalence-of-type-2-diabetes-is-not-increased-in-normal-weight-women-with-pcos
#15
Rasa Pelanis, Jan Roar Mellembakken, Inger Sundström-Poromaa, Pernille Ravn, Laure Morin-Papunen, Juha S Tapanainen, Terhi Piltonen, Johanna Puurunen, Angelica Lindén Hirschberg, Peter Fedorcsak, Marianne Andersen, Dorte Glintborg
STUDY QUESTION: Is oral glucose tolerance test (OGTT) needed in all women with polycystic ovary syndrome (PCOS)? SUMMARY QNSWER: OGTT is not routinely needed in women with PCOS and BMI < 25 kg/m2. WHAT IS KNOWN ALREADY: PCOS is associated with insulin resistance and increased prevalence of prediabetes and Type 2 diabetes (T2D) which is closely linked to obesity and possibly age, ethnicity and PCOS phenotype. Several guidelines recommend OGTT upon diagnosis of PCOS and during follow-up...
September 29, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29040529/insulin-resistance-in-a-large-cohort-of-women-with-polycystic-ovary-syndrome-a-comparison-between-euglycaemic-hyperinsulinaemic-clamp-and-surrogate-indexes
#16
Flavia Tosi, Enzo Bonora, Paolo Moghetti
STUDY QUESTION: Could surrogate indexes identify insulin resistant individuals among women with polycystic ovary syndrome (PCOS)? SUMMARY ANSWER: Surrogate indexes may be able to rule in, but not rule out, insulin resistance in women with PCOS. WHAT IS KNOWN ALREADY: Insulin resistance is a typical finding of women with PCOS and most clinical information on this issue is based upon surrogate indexes of insulin resistance. However, data on the performance of these indexes in PCOS women are very limited...
October 13, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29040417/neonatal-immune-activation-depletes-the-ovarian-follicle-reserve-and-alters-ovarian-acute-inflammatory-mediators-in-neonatal-rats
#17
Erin A Fuller, Luba Sominsky, Jessie M Sutherland, Kate A Redgrove, Lauren Harms, Eileen A McLaughlin, Deborah M Hodgson
Normal ovarian development is crucial for female reproductive success and longevity. Interruptions to the delicate process of initial folliculogenesis may lead to ovarian dysfunction. We have previously demonstrated that an early life immune challenge in the rat, induced by administration of lipopolysaccharide (LPS) on postnatal day (PND) 3 and 5, depletes ovarian follicle reserve long term. Here, we hypothesised that this neonatal immune challenge leads to an increase in peripheral and ovarian inflammatory signalling, contributing to an acute depletion of ovarian follicles...
October 10, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29039499/an-investigation-of-methyl-tert%C3%A2-butyl-ether%C3%A2-induced-cytotoxicity-and-protein-profile-in-chinese-hamster-ovary-cells
#18
Guangshan Xie, Wen-Xu Hong, Li Zhou, Xifei Yang, Haiyan Huang, Desheng Wu, Xinfeng Huang, Weiguo Zhu, Jianjun Liu
Methyl tert-butyl ether (MTBE) is widely used as an oxygenating agent in gasoline to reduce harmful emissions. However, previous studies have demonstrated that MTBE is a cytotoxic substance that has harmful effects in vivo and in vitro. Although remarkable progress has been made in elucidating the mechanisms underlying the MTBE‑induced reproductive toxicological effect in different cell lines, the precise mechanisms remain far from understood. The present study aimed to evaluate whether mammalian ovary cells were sensitive to MTBE exposure in vitro by assessing cell viability, lactate dehydrogenase (LDH) leakage, malondialdehyde (MDA) content and antioxidant enzyme activities...
October 11, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29039178/-potential-clinical-application-of-kisspeptin-in-reproductive-endocrinology
#19
Yanling Fu, Yimin Zhu
Gonadotropin-releasing hormone (GnRH) plays an important role in the process of reproduction. Studies have shown that a family of peptides Kisspeptin can act on GnRH-related neurons, stimulating the secretion of GnRH, and activating the hypothalamic-pituitary-gonadal axis. Both animal experiments and clinical studies have shown that exogenous administration of Kisspeptin is able to induce physiological GnRH release in healthy individuals and those with endocrine-disorders, which brings great hope for treatment of reproductive endocrine diseases...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/29039176/-research-progress-on-the-relationship-of-brown-adipose-tissue-with-polycystic-ovary-syndrome
#20
Xiaohua Fu, Weihai Xu, Shengchun Qiu, Jing Shu
Brown adipose tissue (BAT) holds great promise for the prevention and treatment of metabolism diseases through thermoregulation. Polycystic ovary syndrome (PCOS) is a complex condition with anovulation, hyperandrogenism, and polycystic ovaries, and also manifests glucolipid metabolic disorders. Recent researches have shown that transplantation of BAT into a PCOS rat could significantly alleviate the phenotypes. This article reviews the role of BAT in pathogenesis of PCOS, which may provide information for prevention and treatment of PCOS...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
keyword
keyword
1675
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"