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https://www.readbyqxmd.com/read/30061526/legionellosis-associated-with-recreational-waters-a-systematic-review-of-cases-and-outbreaks-in-swimming-pools-spa-pools-and-similar-environments
#1
Erica Leoni, Federica Catalani, Sofia Marini, Laura Dallolio
Legionella spp. is widespread in many natural and artificial water systems, such as hot water distribution networks, cooling towers, and spas. A particular risk factor has been identified in the use of whirlpools and hot tubs in spa facilities and public baths. However, there has been no systematic synthesis of the published literature reporting legionellosis cases or outbreaks related to swimming/spa pools or similar environments used for recreational purposes (hot springs, hot tubs, whirlpools, natural spas)...
July 30, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/30057837/spontaneous-ruptured-pyomyoma-in-a-nulligravid-female-a-case-report-and-review-of-the-literature
#2
S Read, J Mullins
Introduction: Pyomyoma, or suppurative leiomyoma, is a rare complication of uterine fibroids. It occurs most commonly in the setting of pregnancy, the immediate postpartum period, or postmenopausal status. It may also arise after recent uterine instrumentation, after uterine artery embolization, or in immunocompromised patients. The most likely cause of pyomyoma is vascular compromise followed by bacterial seeding from direct, hematogenous, or lymphatic spread. Diagnosis is difficult, as the condition is rare, presents with vague symptoms, and is difficult to identify on imaging...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30016317/multidrug-resistance-among-escherichia-coli-and-klebsiella-pneumoniae-carried-in-the-gut-of-out-patients-from-pastoralist-communities-of-kasese-district-uganda
#3
Iramiot Jacob Stanley, Henry Kajumbula, Joel Bazira, Catherine Kansiime, Innocent B Rwego, Benon B Asiimwe
BACKGROUND: Antimicrobial resistance is a worldwide public health emergency that requires urgent attention. Most of the effort to prevent this coming catastrophe is occurring in high income countries and we do not know the extent of the problem in low and middle-income countries, largely because of low laboratory capacity coupled with lack of effective surveillance systems. We aimed at establishing the magnitude of antimicrobial resistance among Escherichia coli and Klebsiella pneumoniae carried in the gut of out-patients from pastoralist communities of rural Western Uganda...
2018: PloS One
https://www.readbyqxmd.com/read/30007864/an-outbreak-of-respiratory-tract-infection-due-to-respiratory-syncytial-virus-b-in-a-postpartum-center
#4
Sukhyun Ryu, Bryan Inho Kim, Byung Chul Chun
BACKGROUND: An outbreak of respiratory tract infection due to Respiratory Syncytial Virus (RSV) type B in a postpartum center was reported on February 1, 2017. Investigation was conducted to identify the magnitude, possible source of infection and risk factors for this outbreak on February 2, 2017. METHODS: A retrospective cohort study was conducted. A case was defined as a neonate having respiratory symptoms with or without fever and stayed at the postpartum center between January 1, 2017 and February 3, 2017...
July 11, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/30007502/transmission-of-the-relapsing-fever-spirochete-borrelia-miyamotoi-by-single-transovarially-infected-larval-ixodes-scapularis-ticks
#5
Nicole E Breuner, Andrias Hojgaard, Adam J Replogle, Karen A Boegler, Lars Eisen
The relapsing fever spirochete, Borrelia miyamotoi, is increasingly recognized as a cause of human illness (hard tick-borne relapsing fever) in the United States. We previously demonstrated that single nymphs of the blacklegged tick, Ixodes scapularis, can transmit B. miyamotoi to experimental hosts. However, two recent epidemiological studies from the Northeastern United States indicate that human cases of hard tick-borne relapsing fever peak during late summer, after the spring peak for nymphal tick activity but coincident with the peak seasonal activity period of larval ticks in the Northeast...
July 10, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29983929/evaluation-of-methods-for-linking-household-and-health-care-provider-data-to-estimate-effective-coverage-of-management-of-child-illness-results-of-a-pilot-study-in-southern-province-zambia
#6
Emily D Carter, Micky Ndhlovu, Thomas P Eisele, Emmy Nkhama, Joanne Katz, Melinda Munos
Background: Existing population-based surveys have limited accuracy for estimating the coverage and quality of management of child illness. Linking household survey data with health care provider assessments has been proposed as a means of generating more informative population-level estimates of effective coverage, but methodological issues need to be addressed. Methods: A 2016 survey estimated effective coverage of management of child illness in Southern Province, Zambia, using multiple methods for linking temporally and geographically proximate household and health care provider data...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29963414/-clostridium-perfringens-empyema-in-a-patient-with-metastatic-squamous-cell-carcinoma-of-the-lung
#7
Daniel Jungmyung Oh, Stephen Brecher, Marcus Ruopp
We report a rare case of Clostridium perfringens (CP) empyema in a patient with metastatic squamous cell cancer of the lung. Clostridial empyemas are rare and clinically variable with some reports noting consequent necrotizing infections and septic shock and others noting quick resolution with source control and antibiotic treatment. This is the first case report to our knowledge to report a CP empyema in a patient with lung malignancy. Given the comorbid lung malignancy, the patient's presenting symptoms were mild with only mild shortness of breath, fevers, and generalized weakness despite the large CP empyema...
April 2018: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/29849279/urinary-catheterization-in-infants-when-it-s-knot-so-simple
#8
David C Sheridan, Beech Burns, Megan Mickley
Pediatric fever is one of the most common presenting complaints to emergency departments (ED). While often due to a viral illness, in young children without a source the most common bacterial infection is pyelonephritis. For this reason, when no focal source can be identified a urinary specimen is recommended. In young children who are unable to urinate on demand, a straight catheter is required to obtain a sterile specimen. This is generally a benign procedure and is performed frequently in EDs. We report a case of a young girl who underwent straight bladder catheterization and was subsequently found to have a retained catheter that had become knotted in the bladder...
February 2018: Clinical practice and cases in emergency medicine
https://www.readbyqxmd.com/read/29764368/airborne-geographical-dispersal-of-q-fever-from-livestock-holdings-to-human-communities-a-systematic-review-and-critical-appraisal-of-evidence
#9
Nicholas J Clark, Ricardo J Soares Magalhães
BACKGROUND: Q fever is a zoonotic disease caused by Coxiella burnetii. This bacterium survives harsh conditions and attaches to dust, suggesting environmental dispersal is a risk factor for outbreaks. Spatial epidemiology studies collating evidence on Q fever geographical contamination gradients are needed, as human cases without occupational exposure are increasing worldwide. METHODS: We used a systematic literature search to assess the role of distance from ruminant holdings as a risk factor for human Q fever outbreaks...
May 15, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29700762/a-host-protein-signature-is-superior-to-other-biomarkers-for-differentiating-between-bacterial-and-viral-disease-in-patients-with-respiratory-infection-and-fever-without-source-a-prospective-observational-study
#10
Liat Ashkenazi-Hoffnung, Kfir Oved, Roy Navon, Tom Friedman, Olga Boico, Meital Paz, Gali Kronenfeld, Liat Etshtein, Asi Cohen, Tanya M Gottlieb, Eran Eden, Irina Chistyakov, Isaac Srugo, Adi Klein, Shai Ashkenazi, Oded Scheuerman
Bacterial and viral infections often present with similar symptoms. Etiologic misdiagnosis can alter the trajectory of patient care, including antibiotic overuse. A host-protein signature comprising tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), interferon gamma-induced protein-10 (IP-10), and C-reactive protein (CRP) was validated recently for differentiating bacterial from viral disease. However, a focused head-to-head comparison of its diagnostic performance against other biomarker candidates for this indication was lacking in patients with respiratory infection and fever without source...
July 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29690902/use-of-family-planning-and-child-health-services-in-the-private-sector-an-equity-analysis-of-12-dhs-surveys
#11
Nirali M Chakraborty, Andrea Sprockett
BACKGROUND: A key component of universal health coverage is the ability to access quality healthcare without financial hardship. Poorer individuals are less likely to receive care than wealthier individuals, leading to important differences in health outcomes, and a needed focus on equity. To improve access to healthcare while minimizing financial hardships or inequitable service delivery we need to understand where individuals of different wealth seek care. To ensure progress toward SDG 3, we need to specifically understand where individuals seek reproductive, maternal, and child health services...
April 24, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29659910/household-transmission-of-ebola-virus-risks-and-preventive-factors-freetown-sierra-leone-2015
#12
Mary R Reichler, James Bangura, Dana Bruden, Charles Keimbe, Nadia Duffy, Harold Thomas, Barbara Knust, Ishmail Farmar, Erin Nichols, Amara Jambai, Oliver Morgan, Thomas Hennessy
Background: Knowing risk factors for household transmission of Ebola virus is important to guide preventive measures during Ebola outbreaks. Methods: We enrolled all confirmed persons with Ebola who were the first case in a household, December 2014-April 2015, in Freetown, Sierra Leone, and their household contacts. Cases and contacts were interviewed, contacts followed prospectively through the 21-day incubation period, and secondary cases confirmed by laboratory testing...
July 24, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29619901/inflammatory-biomarkers-to-guide-diagnostic-and-therapeutic-decisions-in-children-presenting-with-fever-without-apparent-source
#13
Giulia Trippella, Luisa Galli, Maurizio de Martino, Elena Chiappini
A systematic review of literature from 2011 to 2016 was performed, in order to evaluate the diagnostic performance of inflammatory biomarkers in children with fever without apparent source and their usefulness in clinical decision-making. Data source was the Pubmed database. Thirteen studies were included, analysing the following biomarkers: erythrocyte sedimentation rate, white blood count, absolute neutrophil count, C-reactive protein (CRP), procalcitonin (PCT), interleukin-6 (IL-6) and the Lab-score (a combination of CRP, PCT and urine dipstick)...
April 5, 2018: Journal of Chemotherapy
https://www.readbyqxmd.com/read/29602480/-tunnelled-central-venous-catheter-infection-during-treatment-with-epoprostenol
#14
M Koszutski, M Faure, A Guillaumot, E Gomez, M Mercy, F Chabot, A Chaouat
INTRODUCTION: Pulmonary arterial hypertension is a pulmonary vascular disease with a poor prognosis. Continuous intravenous treatment with prostacyclin analogues requires the placement of a tunnelled catheter. The occurrence of catheter-related infections in this context is unusual due to the alkaline pH of the prostacyclin analogue solutions. OBSERVATION: A 50-year-old patient with inherited pulmonary artery hypertension, treated with bosentan, sildenafil and epoprostenol, experienced generalized malaise associated with a weight loss of 9kg over a 12-month period without evidence of a source of infection or malignancy...
March 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29601448/antibiotic-overuse-in-children-with-respiratory-syncytial-virus-lower-respiratory-tract-infection
#15
Chantal B van Houten, Christiana Naaktgeboren, Brigitte J M Buiteman, Maaike van der Lee, Adi Klein, Isaac Srugo, Irina Chistyakov, Wouter de Waal, Clemens B Meijssen, Pieter W Meijers, Karin M de Winter-de Groot, Tom F W Wolfs, Yael Shachor-Meyouhas, Michal Stein, Elisabeth A M Sanders, Louis J Bont
BACKGROUND: Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections (LRTI) during the first year of life. Antibiotic treatment is recommended in cases suspected of bacterial co-infection. The aim of this prospective study is to estimate the incidence of bacterial co-infections, and the amount of antibiotic overuse in children infected with RSV using expert panel diagnosis. METHODS: Children one month of age and over with LRTI or fever without source were prospectively recruited in hospitals in the Netherlands and Israel...
March 29, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29566014/pattern-of-medication-selling-and-self-medication-practices-a-study-from-punjab-pakistan
#16
Muhammad Majid Aziz, Imran Masood, Mahreen Yousaf, Hammad Saleem, Dan Ye, Yu Fang
BACKGROUND: Access to medicines without prescription is a major contributing factor for self-medication practices. This study was designed to examine the ratio of non-prescribed medicines sales and self-medication practices in Punjab, Pakistan. This study also evaluates the reasons for self-medication within its communities. METHODS: An observational study was conducted in 272 systemically selected pharmacies to analyze medicines-related sales, with or without prescription...
2018: PloS One
https://www.readbyqxmd.com/read/29462106/prevalence-of-occult-bacteremia-in-infants-with-very-high-fever-without-a-source
#17
Iker Gangoiti, Elva Rodriguez, Ane Zubizarreta, Javier Benito, Santiago Mintegi
We carried out a prospective registry-based cohort study at the emergency department of 363 previously healthy well-appearing infants aged 3-24 months old with fever without a source ≥ 40.5°C based on local protocol. Four were diagnosed with occult bacteremia (1.1%, 95% CI 0-2.2). Recommendations for non-testing for occult bacteremia screening in these children may have to be re-considered when fever ≥40.5°C. Larger studies are needed to confirm these results.
February 16, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29449214/invasive-bacterial-infections-in-young-afebrile-infants-with-a-history-of-fever
#18
Santiago Mintegi, Borja Gomez, Alba Carro, Haydee Diaz, Javier Benito
OBJECTIVE: To determine the prevalence of invasive bacterial infections (IBI, pathogenic bacteria in blood or cerebrospinal fluid) in infants less than 90 days old with fever without a source related to the presence or absence of fever on arrival to the emergency department (ED). DESIGN: Prospective registry-based cohort study. SETTING: Paediatric ED of a tertiary teaching hospital. PATIENTS: We included infants less than 90 days old with a history of fever evaluated in the ED from 2003 to 2016...
July 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29408951/malaria-coinfections-in-febrile-pediatric-inpatients-a-hospital-based-study-from-ghana
#19
Benedikt Hogan, Daniel Eibach, Ralf Krumkamp, Nimako Sarpong, Denise Dekker, Benno Kreuels, Oumou Maiga-Ascofaré, Kennedy Gyau Boahen, Charity Wiafe Akenten, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Jürgen May
Background: The epidemiology of pediatric febrile illness is shifting in sub-Saharan Africa, but malaria remains a major cause of childhood morbidity and mortality. The present study describes causes of febrile illness in hospitalized children in Ghana and aims to determine the burden of malaria coinfections and their association with parasite densities. Methods: In a prospective study, children (aged ≥30 days and ≤15 years) with fever ≥38.0°C were recruited after admission to the pediatric ward of a primary hospital in Ghana...
June 1, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29399582/outbreak-investigation-of-pertussis-in-an-elementary-school-a-case-control-study-among-vaccinated-students
#20
Sukhyun Ryu, Joon Jai Kim, Meng-Yu Chen, Hyunju Jin, Hyun Kyung Lee, Byung Chul Chun
Purpose: A pertussis patient from an elementary school, in Gyeonggi Province, Korea, was notified to public health authority on July 25, 2017. Epidemiologic investigation was conducted to identify the magnitude, possible source of infection and risk factors for this outbreak on August 17, 2017. Materials and Methods: A case was defined as the school student experiencing cough for more than two weeks with or without paroxysmal, whoop, or post-tussive vomiting. Control was defined as the student polymerase chain reaction-negative at the school...
January 2018: Clinical and Experimental Vaccine Research
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