A Caicedo, I Tachtsidis, M D Papademetriou, S Van Huffel
Extra-Corporeal Membrane Oxygenation (ECMO) is a life support system for infants and children with cardio-respiratory failure. During ECMO it is possible to have unstable cerebral haemodynamics, due to strong oscillations in the systemic variables, among other factors, which may lead to brain damage in the patients. Therefore, monitoring the coupling between cerebral haemodynamics and systemic signals might alert us of possible imminent brain damage. In this study we explore the use of orthogonal and oblique subspace projections in the decoupling of these variables, by assessing the ratio between the projections of the haemodynamic variables, onto the subspace spanned by the systemic variables, and the original signals...
2012: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society