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Yuki Fukuoka, Takuma Narita, Hiroki Fujita, Tsukasa Morii, Takehiro Sato, Mariko Harada Sassa, Yuichiro Yamada
AIMS/INTRODUCTION: To investigate the prevalence of sarcopenia, its related factors, and indicators of physical evaluation in elderly diabetic patients. MATERIALS AND METHODS: This was a cross-sectional observation study. Total 267 diabetic patients (159 men, 108 women) aged > 65 years were recruited in our study. Skeletal muscle mass index, grip strength, and usual gait speed were measured to diagnose sarcopenia according to the Asian Working Group for Sarcopenia...
August 11, 2018: Journal of Diabetes Investigation
Beth Hands, Paola Chivers, Tegan Grace, Fleur McIntyre
BACKGROUND: There are few exercise interventions focused on adolescents with low motor competence and most interventions are short with little follow up and engagement over time. METHODS AND PROCEDURES: Fifty-eight adolescents with low motor competence (39 males, Mean Age  = 13.6, SD = 1.4 years) attended an exercise clinic twice a week for each 13 week program. Two programs ran each year, and participants attended for as long as they felt progress was made or they turned 18 years of age...
August 7, 2018: Research in Developmental Disabilities
Martin La Mare
No abstract text is available yet for this article.
2018: Primary Dental Journal
Y Okubo, M Nemoto, Y Osuka, S Jung, S Seino, R Figueroa, G Vinyes-Pares, E A Offord, M Shevlyakova, D Breuille, K Tanaka
OBJECTIVE: Develop and evaluate the feasibility and validity of the Nutrition and Functionality Assessment (NFA) which identifies "target" older adults who could benefit from a personalized program following evaluation of their nutrition status and physical functionality. DESIGN: Cross-sectional study. SETTING: Community and geriatric day-care centers and university in Japan. PARTICIPANTS: 267 older adults aged 65-90...
2018: Journal of Frailty & Aging
J M Beasley, M A Sevick, L Kirshner, M Mangold, J Chodosh
BACKGROUND: Through diet and exercise interventions, community centers offer an opportunity to address health-related issues for some of the oldest, most vulnerable members of our society. OBJECTIVES: The purpose of this investigation is to draw upon nationwide data to better characterize the population served by the congregate meals program and to gather more detailed information on a local level to identify opportunities for service enhancement to improve the health and well-being of older adults...
2018: Journal of Frailty & Aging
N W Bray, T J Doherty, M Montero-Odasso
BACKGROUND: Vitamin D deficiency is ubiquitous in frailty but the effectiveness of vitamin D supplementation to improve outcomes in frail individuals is unclear. It has been postulated that higher than the current recommended doses (800 IU/day) may be needed to achieve a neuromuscular effect in frail individuals. OBJECTIVES: 1) determine if 4000 IU per day of vitamin D3 is safe for frail older adults; and 2) establish the efficacy of this dose to improve physical performance outcomes in this population...
2018: Journal of Frailty & Aging
T David Luo, Fiesky A Nunez, Elizabeth A Newman, Fiesky A Nunez
BACKGROUND: Distal radius articular step-off or deformity may cause posttraumatic arthritis and poor functional outcome. The purpose of this study was to evaluate pain and functional outcomes in patients with malunited partial articular distal radius fractures who underwent corrective osteotomy. We hypothesized that anatomic restoration of distal radius articular surface after a malunited partial articular distal radius fracture results in improvement in pain and functional measures and delays the development of posttraumatic arthritis...
August 10, 2018: Hand: Official Journal of the American Association for Hand Surgery
A V Hauger, A Bergland, K Holvik, A Ståhle, N Emaus, B H Strand
Low bone mineral density (BMD) gives an increased risk of fractures, which can lead to premature death. Can BMD of the wrist predict mortality? BMD consistent with osteopenia and osteoporosis gave a significantly increased risk of death for both men and women in a general population in Tromsø, Norway. INTRODUCTION: To investigate if bone mineral density (BMD) levels of the distal forearm, consistent with osteopenia and osteoporosis, can predict mortality and if grip strength is an effect modifier...
August 9, 2018: Osteoporosis International
Rossana Gómez-Campos, Cynthia Lee Andruske, Miguel de Arruda, Jose Sulla-Torres, Jaime Pacheco-Carrillo, Camilo Urra-Albornoz, Marco Cossio-Bolaños
BACKGROUND: Hand grip strength (HGS) is associated with a number of causes resulting in cardiovascular death, in addition to bone fragility, and the presence of sarcopenia. The goal of our study was to analyze HGS of students based on chronological and biological age and propose normative standards for children and adolescents from Chile. METHODS: We studied 4604 school children of both sexes between the ages of 6.0 and 17.9 years of age. Weight, standing height, sitting height, and hand grip strength (HGS- right and left) were measured...
2018: PloS One
O Owoeye, F O Awoyemi, E O Ajiboye
Cisplatin (CIS), a known anticancer drug, has side effects initiated by oxidative damage which hinders its use.Raffia hookeri pulp extract (RHPE), reported to possess antioxidant activity should mitigate cisplatin toxicity. The presentstudy examined the potential of RHPE to reduce brain damage in rats exposed to cisplatin. Forty eight female rats (150 g -220 g) were randomized into four groups (n = 12) viz: Group 1 served as control received distilled water daily, Group 2received 100 mg/kg body weight of RHPE, Group 3 received CIS (7...
June 30, 2018: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
Pierre Delanaye, Kevin Quinonez, Fanny Buckinx, Jean-Marie Krzesinski, Olivier Bruyère
Background: Hand grip strength (HGS) is a key measurement in the assessment of frailty phenotype in haemodialysis patients. However, the measurement is not very standardized, and notably, current data on the potential impact of a haemodialysis session on the results are both limited and controversial. In the present analysis, we compared HGS results before and after a haemodialysis session in 101 patients. Methods: In the current observational study, HGS has been measured in adult haemodialysis patients on the same day, first before connection to the dialysis machine and then just after disconnection...
August 2018: Clinical Kidney Journal
Ana Zelic Kerep, Jacob Broome, Filip Pirsl, Lauren M Curtis, Seth M Steinberg, Sandra A Mitchell, Edward W Cowen, Dominique C Pichard, Galen O Joe, Leora E Comis, Jacqueline W Mays, Manuel B Datiles, Pamela Stratton, Jessica Zolton, Ann Berger, Jennifer Hendricks, Megan Kenyon, Judy Baruffaldi, Irina Titarenko, Drazen Pulanic, Kristin Baird, Daniel H Fowler, Ronald E Gress, Steven Z Pavletic
In 2005, the National Institutes of Health (NIH) chronic graft-versus-host disease (cGVHD) consensus project provided diagnosis and staging criteria, based mostly on clinical experience and expert opinion. These criteria were revised in 2014, aiming to provide enhanced specificity and clarity. However, the impact of 2014 changes to the original NIH cGVHD severity scoring criteria has not been reported. In this study, 284 patients, prospectively enrolled on the National Cancer Institute's cross-sectional cGVHD natural history study, were scored using the 2005 NIH cGVHD criteria and then rescored according to the 2014 modifications...
August 8, 2018: Bone Marrow Transplantation
Brendan W Smith, Justin B Rowe, David J Reinkensmeyer
During trial-to-trial movement adaptation, the motor system systematically reduces extraneous muscle forces when kinematic errors experienced on previous movements are small, a phenomenon termed "slacking". There is also growing evidence that the motor system slacks continuously (i.e. in real-time) during arm movement or grip force control, but the initiation of this slacking is not well characterized, obfuscating its physiological cause. Here we addressed this issue by asking participants (N=32) to track discrete force targets presented visually using isometric grip force, then applying a brief, subtle error clamp to that visual feedback on random trials...
August 8, 2018: Journal of Neurophysiology
Yiu Ming Wong
Fibrosis of skeletal muscle following acupuncture is an iatrogenic disorder. The present case illustrates a patient with a unilateral fibrotic formation on a thumb muscle after acupuncture injection therapy with red sage. The patient in the present case was a counter-terrorism police officer with right-handedness; he noted a palpable nodule three months after injection therapy at his left first dorsal interosseous in which the acupuncture point LI4 (He Gu) is located. He also found a reduction in the strength of his left pinch grip that noticeably affected his left handgun marksmanship...
September 2017: Journal of Pharmacopuncture
Barbara Pellegrini, Thomas Leonhard Stöggl, Hans-Christer Holmberg
Here, our aim was to describe the major changes in cross-country (XC) skiing in recent decades, as well as potential future developments. XC skiing has been an Olympic event since the very first Winter Games in Chamonix, France, in 1924. Over the past decades, considerable developments in skiing techniques and improvements in equipment and track preparation have increased skiing speed. In contrast to the numerous investigations on the physiological determinants of successful performance, key biomechanical factors have been less explored...
2018: Frontiers in Physiology
Songil Lee, Gyouhyung Kyung, Jihhyeon Yi, Donghee Choi, Sungryul Park, Byeonghwa Choi, Seungbae Lee
OBJECTIVE: The authors aimed to identify ergonomic smartphone forms by investigating the effects of hand length, four major smartphone dimensions (height, width, thickness, and edge roundness), and smartphone mass on grip comfort and design attractiveness. BACKGROUND: Despite their potential effect on grip comfort and design attractiveness, the dimensions specified above have never been simultaneously considered in a study investigating smartphone gripping. METHOD: Seventy-two young individuals participated in a three-stage study...
August 7, 2018: Human Factors
Janet M Chiang, George A Kaysen, Mark Segal, Glenn M Chertow, Cynthia Delgado, Kirsten L Johansen
Background: Despite the high prevalence of frailty among patients receiving hemodialysis, few preventable or treatable contributing causes have been identified. Hypogonadism is also common in this population and low serum testosterone concentrations share several clinical phenotypes with frailty. We hypothesized that low serum testosterone concentrations would be associated with frailty and several of its individual components. Methods: We used data from 440 men from A Cohort Study To Investigate the Value of Exercise in ESRD/Analysis Designed to Investigate the Paradox of Obesity and Survival in ESRD, a longitudinal study that recruited participants from 14 dialysis centers in Atlanta, GA and the San Francisco, CA Bay Area from 2009 to 2011...
August 1, 2018: Nephrology, Dialysis, Transplantation
Kun Ma, Haoyu Wu, Peng Li, Baixiang Li
Atrazine (2-chloro-4-ethylamino-6-isopropylamine-1,3,5-triazine; ATR) has been demonstrated to regulate autophagy- and apoptosis-related proteins in doparminergic neuronal damage. In our study, we investigated the role of LC3-II in ATR-induced degeneration of dopaminergic neurons. In vivo dopaminergic neuron degeneration model was set up with ATR treatment and confirmed by the behavioral responses and pathological analysis. Dopaminergic neuron cells were transfected with LC3-II siRNA and treated with ATR to observe cell survival and reactive oxygen species release...
August 2, 2018: Acta Biochimica et Biophysica Sinica
Jun-Il Yoo, Mi-Ji Kim, Jae-Bum Na, Yun-Hong Chun, Young-Jin Park, Yongwhi Park, Young-Sool Hah, Yong-Chan Ha, Ki Soo Park
BACKGROUND: The aim of this study is to determine whether there is correlation between endothelial function and skeletal muscle function measured by hand grip strength in elderly women. METHODS: This cross-sectional study used data of NAMGARAM-2 cohort. The NAMGARAM-2 cohort consisted of a group of people living in three rural communities. They were enrolled for studies on activity limitation due to age-related musculoskeletal disorders including knee osteoarthritis, osteoporosis, and sarcopenia...
August 6, 2018: Journal of Cachexia, Sarcopenia and Muscle
Chuanjiang Li, Jian Ren, Huaiqi Huang, Bin Wang, Yanfei Zhu, Huosheng Hu
BACKGROUND: For the functional control of prosthetic hand, it is insufficient to obtain only the motion pattern information. As far as practicality is concerned, the control of the prosthetic hand force is indispensable. The application value of prosthetic hand will be greatly improved if the stable grip of prosthetic hand can be achieved. To address this problem, in this study, a bio-signal control method for grasping control of a prosthetic hand is proposed to improve patient's sense of using prosthetic hand and the thus improving the quality of life...
August 6, 2018: Biomedical Engineering Online
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