keyword
https://read.qxmd.com/read/38647016/recent-developments-in-the-diagnosis-of-pancreatic-neuroendocrine-neoplasms
#1
REVIEW
Anna Battistella, Matteo Tacelli, Paola Mapelli, Marco Schiavo Lena, Valentina Andreasi, Luana Genova, Francesca Muffatti, Francesco De Cobelli, Stefano Partelli, Massimo Falconi
INTRODUCTION: Pancreatic Neuroendocrine Neoplasms (PanNENs) are characterized by a highly heterogeneous clinical and biological behavior, making their diagnosis challenging. PanNENs diagnostic work-up mainly relies on biochemical markers, pathological examination, and imaging evaluation. The latter including radiological imaging (i.e. computed tomography [CT] and magnetic resonance imaging [MRI]), functional imaging (i.e. 68Gallium [68 Ga]Ga-DOTA-peptide PET/CT and Fluorine-18 fluorodeoxyglucose [18F]FDG PET/CT), and endoscopic ultrasound (EUS) with its associated procedures...
April 22, 2024: Expert Review of Gastroenterology & Hepatology
https://read.qxmd.com/read/38646436/paratesticular-metastasis-from-colorectal-adenocarcinoma-presenting-as-hydrocele-a-rare-case-report-and-literature-review
#2
XiaoJun Huang, KeLi Xu, Yin Zhao, MinHui Chen, ZheYang Li
Colorectal cancer, with the liver being the most common site of distant metastasis, followed by the lungs and bones. Although reports of metastasis to the testis exist, paratesticular metastasis is extremely rare. A 37-year-old male presented with scrotal swelling. Ultrasound revealed hydrocele of the tunica vaginalis. The patient underwent routine surgical treatment, and postoperative pathology of the tunica vaginalis indicated adenocarcinoma of gastrointestinal origin. Colonoscopic biopsy confirmed adenocarcinoma of the sigmoid colon...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38646388/comparative-efficacy-of-non-invasive-therapies-in-temporomandibular-joint-dysfunction-a-systematic-review
#3
REVIEW
Hesham A Alowaimer, Sultan S Al Shutwi, Mohammed K Alsaegh, Ohood M Alruwaili, Abdullah R Alrashed, Salwa H AlQahtani, Mohammed S Batais
Temporomandibular disorder (TMD) is a multifaceted disorder impacting the temporomandibular joint (TMJ), causing substantial discomfort and functional limitations. This systematic review aims to comprehensively assess the effectiveness of non-invasive treatment modalities for TMJ dysfunction, prioritizing a definitive protocol to ensure patient safety and enhance quality of life. Employing the PRISMA guidelines, we meticulously analyzed 20 studies from a pool of 1,417 articles sourced from databases such as PubMed, Google Scholar, ScienceDirect, and Medline...
March 2024: Curēus
https://read.qxmd.com/read/38646273/assessment-of-pre-analytical-errors-and-fostering-strategies-to-enhance-accurate-results-and-efficient-turnaround-times-in-the-cytology-laboratory-of-a-tertiary-care-hospital
#4
JOURNAL ARTICLE
Vallal Kani, Kavitha K, Sulochana Sonti
Introduction Pre-analytical errors in cytology laboratories can significantly impact the accuracy of diagnostic results and turnaround times, ultimately affecting patient care. This article presents an evaluation of pre-analytical errors and proposes fostering strategies to enhance accuracy and efficiency in the cytology laboratory of a tertiary care hospital. The background discusses the importance of pre-analytical processes in ensuring reliable cytological diagnoses and the common errors encountered in specimen collection, handling, and transportation...
March 2024: Curēus
https://read.qxmd.com/read/38645656/pituitary-stalk-interruption-syndrome-with-excessive-height-growth-combined-with-congenital-absence-of-the-uterus-and-ovaries-a-rare-case-report-and-review-of-the-literature
#5
Rongqian Wu, Jixiong Xu
AIM: Pituitary stalk interruption syndrome is a relatively rare disease. Patients with this disease usually have different degrees of short stature in adulthood. The purpose of this case report is to highlight a special case of unusually elongated limbs with excessive height growth and congenital absence of uterus and ovary, so as to improve clinicians understanding of the atypical manifestations of pituitary stalk interruption syndrome and provide reference for the clinical diagnosis and treatment of the disease...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38645585/a-review-of-functional-neuromodulation-in-humans-using-low-intensity-transcranial-focused-ultrasound
#6
REVIEW
Kyuheon Lee, Tae Young Park, Wonhye Lee, Hyungmin Kim
Transcranial ultrasonic neuromodulation is a rapidly burgeoning field where low-intensity transcranial focused ultrasound (tFUS), with exquisite spatial resolution and deep tissue penetration, is used to non-invasively activate or suppress neural activity in specific brain regions. Over the past decade, there has been a rapid increase of tFUS neuromodulation studies in healthy humans and subjects with central nervous system (CNS) disease conditions, including a recent surge of clinical investigations in patients...
May 2024: Biomedical Engineering Letters
https://read.qxmd.com/read/38645424/outcomes-of-endoscopic-ultrasound-guided-ablation-and-minimally-invasive-surgery-in-the-treatment-of-pancreatic-insulinoma-a-systematic-review-and-meta-analysis
#7
Dan Xiao, Li Zhu, Si Xiong, Xu Yan, Qin Jiang, Ao Wang, Yegui Jia
BACKGROUND AND AIMS: Most pancreatic insulinomas can be treated by minimally invasive modalities. The aim of this meta-analysis was to assess the clinical outcomes of endoscopic ultrasound (EUS)-guided ablation and minimally invasive surgery (MIS) in the treatment of pancreatic insulinoma. MATERIALS AND METHODS: Online databases were searched for relevant studies. The primary aim was to compare the rates of adverse events (AEs) and the secondary aims were to compare the clinical and technical success rates, length of hospital stays, and symptom recurrence rates between EUS and MIS approaches...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38644713/smart-nanobiomaterials-for-gene-delivery-in-localized-cancer-therapy-an-overview-from-emerging-materials-and-devices-to-clinical-applications
#8
JOURNAL ARTICLE
Armin Shamaeizadeh, Anahita Beigi, Seyed Morteza Naghib, Maryam Tajabadi, Mehdi Rahmanian, M R Mozafari
Researchers in various fields continue to discover improved ways of local delivery of drugs to specific locations and try to increase the efficiency of these methods. Extensive research has been done on smart nano-biomaterials for drug delivery systems (DDS) in different dimensions. With the advancement of biomedical nanotechnology, conventional smart DDS with stimuli- responsive capability has been developed. Smart nano-biomaterials can respond to environmental changes caused by endogenous or exogenous elements: endogenous factors such as environmental pH, temperature gradient, enzymes, oxidation, and reduction potential...
April 19, 2024: Current Cancer Drug Targets
https://read.qxmd.com/read/38644353/ultrasonic-processing-effects-on-the-physicochemical-and-microbiological-aspects-of-dairy-products
#9
REVIEW
Kaavya Rathnakumar, Surangna Jain, Nancy Awasti, Pranav Vashisht, Priyamvada Thorakkattu, Bharathi Ramesh, Gayathri Balakrishnan, Karthik Sajith Babu, Seema Ramniwas, Sarvesh Rustagi, R Pandiselvam
Dairy products that are contaminated by pathogenic microorganisms through unhygienic farm practices, improper transportation, and inadequate quality control can cause foodborne illness. Furthermore, inadequate storage conditions can increase the microflora of natural spoilage, leading to rapid deterioration. Ultrasound processing is a popular technology used to improve the quality of milk products using high-frequency sound waves. It can improve food safety and shelf life by modifying milk protein and fats without negatively affecting nutritional profile and sensory properties, such as taste, texture, and flavor...
April 21, 2024: Critical Reviews in Biotechnology
https://read.qxmd.com/read/38644241/-endoscopic-response-evaluation-in-gastrointestinal-cancers-after-neoadjuvant-chemora-diotherapy
#10
JOURNAL ARTICLE
S J Li, J Wang, Q Wu
Neoadjuvant chemoradiotherapy has emerged as the standard treatment for locally advanced rectal cancer, esophageal cancer and gastroesophageal junction cancer which can not only improve the rate of local control but also induce pathological complete response in some patients. For patients who have achieved clinical complete response after neoadjuvant therapy, the watch & wait strategy and organ preservation could reduce unnecessary surgery and minimize the risk of postoperative complications, meanwhile greatly improve patients' quality of life without affecting the oncologic outcome...
April 25, 2024: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38643647/multimode-ultrasonic-assisted-decontamination-of-fruits-and-vegetables-a-review
#11
REVIEW
Yanhua Yu, Yuqing Wang, Clinton Emeka Okonkwo, Li Chen, Cunshan Zhou
Fruits and vegetables (F&V) are a significant part of our diet consumption. Microbial and pesticide residues are the predominant safety hazards of F&V consumption. Ordinary water washing has a very limited effect on removing microorganisms and pesticide residues and requires high water usage. Ultrasound, as an environmentally friendly technology, shows excellent potential for reducing microbial contamination and pesticide residue. This paper summarizes the research on ultrasound application in F&V washing, including the removal of microbial and pesticide residues and the comprehensive effect on their physicochemical characteristics...
April 15, 2024: Food Chemistry
https://read.qxmd.com/read/38643604/simus3-an-open-source-simulator-for-3-d-ultrasound-imaging
#12
JOURNAL ARTICLE
Damien Garcia, François Varray
BACKGROUND AND OBJECTIVE: Computational Ultrasound Imaging (CUI) has become increasingly popular in the medical ultrasound community, facilitated by free simulation software. These tools enable the design and exploration of transmit sequences, transducer arrays, and signal processing. We recently introduced SIMUS, a frequency-based ultrasound simulator within the open-source MUST toolbox, which offers numerical advantages and allows easy consideration of frequency-dependent factors. In response to the growing interest in simulating ultrasound imaging with 2-D matrix arrays, we present 3-D versions, PFIELD3 and SIMUS3...
April 10, 2024: Computer Methods and Programs in Biomedicine
https://read.qxmd.com/read/38643521/acute-phase-determinant-of-post-thrombotic-syndrome-a-review-of-the-literature
#13
REVIEW
Lina Khider, Benjamin Planquette, David M Smadja, Olivier Sanchez, Carla Rial, Guillaume Goudot, Emmanuel Messas, Tristan Mirault, Nicolas Gendron
BACKGROUND: Post-thrombotic syndrome (PTS) is the main long-term complication of deep vein thrombosis (DVT). Several therapies are being evaluated to prevent or to treat PTS. Identifying the patients most likely to benefit from these therapies presents a significant challenge. OBJECTIVES: The objective of this review was to identify risk factors for PTS during the acute phase of DVT. ELIGIBILITY CRITERIA: We searched the PubMed and Cochrane databases for studies published between January 2000 and January 2021, including randomized clinical trials, meta-analyses, systematic reviews and observational studies...
April 12, 2024: Thrombosis Research
https://read.qxmd.com/read/38643184/self-management-including-exercise-education-and-activity-modification-compared-to-usual-care-for-adolescents-with-osgood-schlatter-the-sogood-trial-protocol-of-a-randomized-controlled-superiority-trial
#14
JOURNAL ARTICLE
Kasper Krommes, Kristian Thorborg, Mikkel Bek Clausen, Michael Skovdal Rathleff, Jens Lykkegaard Olesen, Thomas Kallemose, Per Hölmich
BACKGROUND: Osgood-Schlatter is the most frequent growth-related injury affecting about 10% of physically active adolescents. It can cause long-term pain and limitations in sports and physical activity, with potential sequela well into adulthood. The management of Osgood-Schlatter is very heterogeneous. Recent systematic reviews have found low level evidence for surgical intervention and injection therapies, and an absence of studies on conservative management. Recently, a novel self-management approach with exercise, education, and activity modification, demonstrated favorable outcomes for adolescents with patellofemoral pain and Osgood-Schlatter in prospective cohort studies...
April 20, 2024: BMC Sports Science, Medicine and Rehabilitation
https://read.qxmd.com/read/38643005/prehospital-identification-of-intracerebral-haemorrhage-a-scoping-review-of-early-clinical-features-and-portable-devices
#15
REVIEW
Mohammed Almubayyidh, Ibrahim Alghamdi, Adrian Robert Parry-Jones, David Jenkins
INTRODUCTION: Prehospital identification of intracerebral haemorrhage (ICH) in suspected stroke cases may enable the initiation of appropriate treatments and facilitate better-informed transport decisions. This scoping review aims to examine the literature to identify early clinical features and portable devices for the detection of ICH in the prehospital setting. METHODS: Three databases were searched via Ovid (MEDLINE, EMBASE and CENTRAL) from inception to August 2022 using prespecified search strategies...
April 19, 2024: BMJ Open
https://read.qxmd.com/read/38642432/ectopic-pregnancy-located-at-pelvic-wall-and-liver-two-uncommon-case-reports-from-vietnam-and-mini-review-literature
#16
Thanh Hai Pham, Van Hoang Bui, Van Hung Nguyen, Phuc Nhon Nguyen
INTRODUCTION AND IMPORTANCE: Abdominal ectopic pregnancy (AEP) located at hepatic region and pelvic-wall ectopic pregnancy (EP) are rare entities, that provoking a potentially life-threatening condition. Due to insufficient data, a proper management of non-specific types remains a challenge for all gynecologists worldwide. CASE PRESENTATION: Two child-bearing age women were hospitalized due to delayed menstruation and a urine pregnancy test was positive without a determination of intrauterine pregnancy...
April 4, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38642365/combined-first-trimester-screening-and-invasive-diagnostics-for-atypical-chromosomal-aberrations-danish-nationwide-data-on-prenatal-profiles-and-detection-compared-with-nipt
#17
JOURNAL ARTICLE
K Gadsbøll, I Vogel, S E Kristensen, L H Pedersen, J Hyett, O B Petersen
OBJECTIVE: To examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy number variants (pCNVs). Further, we wanted to quantify the performance of combined first-trimester screening (cFTS) and a second-trimester anomaly scan in detecting these conditions. Finally, we aimed to estimate the consequences of a policy of using non-invasive prenatal testing (NIPT) rather than invasive testing with chromosomal microarray (CMA) to manage pregnancies identified as high risk from cFTS...
April 20, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38642342/management-and-outcome-of-fetal-abdominal-cysts-in-first-trimester-systematic-review-of-the-literature
#18
REVIEW
E Passananti, E Bevilacqua, G di Marco, F Felici, M Trapani, V Ciavarro, C Di Ilio, A Lanzone, A Familiari
OBJECTIVES: The finding of an abdominal cyst during pregnancy has an estimated prevalence of 1 in 1000 pregnancies, mostly in second and third trimester. The detection of a fetal abdominal cyst during the first trimester scan is a rare event, whose natural history and prognosis are often unknown and unpredictable as these anomalies can be related to various underlying conditions and originate from different structures. The aim of this study is to evaluate the outcome of fetal abdominal cysts detected in the first trimester in order to understand their possible clinical significance and to offer the proper management according to the available data...
April 20, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38642268/prospects-of-perfusion-contrast-enhanced-ultrasound-ce-us-in-diagnosing-axillary-lymph-node-metastases-in-breast-cancer-a-comparison-with-lymphatic-ce-us
#19
REVIEW
Naoko Mori, Li Li, Masazumi Matsuda, Yu Mori, Shunji Mugikura
Accurate diagnosis of lymph node (LN) metastasis is vital for prognosis and treatment in patients with breast cancer. Imaging 1modalities such as ultrasound (US), MRI, CT, and 18F-FDG PET/CT are used for preoperative assessment. While conventional US is commonly recommended due to its resolution and sensitivity, it has limitations such as operator subjectivity and difficulty detecting small metastases. This review shows the microanatomy of axillary LNs to enhance accurate diagnosis and the characteristics of contrast-enhanced US (CE-US), which utilizes intravascular microbubble contrast agents, making it ideal for vascular imaging...
April 20, 2024: Journal of Medical Ultrasonics
https://read.qxmd.com/read/38641829/kidney-and-urogenital-abnormalities-in-down-syndrome-a-meta-analysis
#20
JOURNAL ARTICLE
Caterina Maria Rossetti, Giacomo D Simonetti, Mario G Bianchetti, Sebastiano A G Lava, Giorgio Treglia, Carlo Agostoni, Gregorio P Milani, J Peter de Winter
BACKGROUND: Reviews on Down syndrome do not or only marginally address the issue of kidney and urogenital tract abnormalities, and lower urinary tract dysfunctions. Hence, we performed a meta-analysis of the literature.  METHODS: A literature search was undertaken in the Library of Medicine, Web of Science and Excerpta Medica. The search algorithm combined various keywords: (Down syndrome OR trisomy 21 OR mongolism) AND (kidney OR urinary tract OR bladder) AND (malformation OR dysfunction OR anomaly OR abnormality OR size)...
April 20, 2024: Italian Journal of Pediatrics
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