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Osseointegration

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https://www.readbyqxmd.com/read/28230589/effects-of-local-and-systemic-zoledronic-acid-application-on-titanium-implant-osseointegration-an-experimental-study-conducted-on-two-surface-types
#1
Serkan Dundar, Ferhan Yaman, Orhan Gecor, Omer Cakmak, Mustafa Kirtay, Tuba Talo Yildirim, Tahir Karaman, Mehmet Emre Benlidayi
The aim of this study was to evaluate the effects of local and systemic zoledronic acid (ZA) applications on titaniumoksit ceramic blasted (TiO-CB)- and sandblasted large acid-grit (SLA)-surfaced titanium implant osseointegration. Twelve New Zealand White rabbits were used in the study, divided into 6 groups: the TiO-CB (TiO-CB-CNT) (n = 2) and SLA (SLA-CNT) (n = 2) control groups in which TiO-CB- and SLA-surfaced titanium implants were surgically inserted into rabbit tibias but no treatment was applied; the TiO-CB (TiO-CB-LZA) (n = 2) and SLA (SLA-LZA) (n = 2) local ZA groups in which 1 mL of normal saline solution containing 2 mg of ZA was injected into sockets and after this the implants were integrated; and the TiO-CB (TiO-CB-SZA) (n = 2) and SLA (SLA-SZA) (n = 2) systemic ZA groups in which a single infusion of 0...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28229851/-skeletal-anchorage-in-the-past-today-and-tomorrow
#2
Birte Melsen, Michel Dalstra
INTRODUCTION: Skeletal anchorage was not introduced as an alternative to conventional anchorage modalities. The first skeletal anchorage was a ligature through a hole in the infrazygomatic crest. This was replaced by surgical screws and finally the TADs, which were optimized with respect to the material and morphology, were developed. A bracket-like head allows for the use of the mini-implant as indirect anchorage, but should not be a tool for lost control resulting from badly planned biomechanics or failing compliance...
March 2017: L' Orthodontie Française
https://www.readbyqxmd.com/read/28229193/osseointegrated-prostheses-for-rehabilitation-following-amputation-the-pioneering-swedish-model
#3
Yan Li, Rickard Brånemark
The direct attachment of osseointegrated (OI) prostheses to the skeleton avoids the inherent problems of socket suspension. It also provides physiological weight bearing, improved range of motion in the proximal joint, as well as osseoperceptive sensory feedback, enabling better control of the artificial limbs by amputees. The present article briefly reviews the pioneering efforts on extremity osseointegration surgeries in Sweden and the development of the OPRA (Osseointegrated Prostheses for the Rehabilitation of Amputees) program...
February 22, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28228786/hydroxyapatite-in-total-hip-arthroplasty-our-experience-with-a-plasma-spray-porous-titanium-alloy-hydroxyapatite-double-coated-cementless-stem
#4
Iacopo Castellini, Lorenzo Andreani, Paolo Domenico Parchi, Enrico Bonicoli, Nicola Piolanti, Francesca Risoli, Michele Lisanti
PURPOSE: Total hip arthroplasty could fail due to many factors and one of the most common is the aseptic loosening. In order to achieve an effective osseointegration and reduce risk of lossening, the use of cemented implant, contact porous bearing surface and organic coating were developed. Aim of this study was to evaluate clinical and radiological mid-term outcomes of a porous titanium alloy/hydroxyapatite double coating manufactured cementless femoral stem applied with "plasma spray" technique and to demonstrate the possibility to use this stem in different types of femoral canals...
September 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/28226494/upper-extremity-prosthesis-user-perspectives-on-unmet-needs-and-innovative-technology
#5
Heather L Benz, Jia Yao, Laura Rose, Okan Olgac, Karen Kreutz, Anindita Saha, Eugene F Civillico, Heather L Benz, Jia Yao, Laura Rose, Okan Olgac, Karen Kreutz, Anindita Saha, Eugene F Civillico, Laura Rose, Heather L Benz, Anindita Saha, Okan Olgac, Eugene F Civillico, Karen Kreutz, Jia Yao
The needs of individuals with upper limb amputation and congenital limb difference are not being fully met by current prostheses, as evidenced by prosthesis rejection, non-wear, and user reports of pain and challenging activities. Emerging technologies such as dexterous sensorized robotic limbs, osseointegrated prostheses, implantable EMG electrodes, and electrical stimulation for sensory feedback have the potential to address unmet needs, but pose additional risks. We plan to assess upper limb prosthesis user needs and perspectives on these new benefits and risks using an extensive quantitative survey...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224420/early-osseointegration-of-implants-with-cortex-like-tio2-coatings-formed-by-micro-arc-oxidation-a-histomorphometric-study-in-rabbits
#6
Hong-Zhi Zhou, Ya-da Li, Lin Liu, Xiao-Dong Chen, Wei-Qiang Wang, Guo-Wu Ma, Yu-Cheng Su, Min Qi, Bin Shi
In our previous studies, a novel cortex-like TiO2 coating was prepared on Ti surface through micro-arc oxidation (MAO) by using sodium tetraborate as electrolyte, and the effects of the coating on cell attachment were testified. This study aimed to investigate the effects of this cortex-like MAO coating on osseointegration. A sand-blasting and acid-etching (SLA) coating that has been widely used in clinical practice served as control. Topographical and chemical characterizations were conducted by scanning electron microscopy, energy dispersive X-ray spectrometer, X-ray diffraction, contact angle meter, and step profiler...
February 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28222880/success-rate-and-strength-of-osseointegration-of-immediately-loaded-uv-photofunctionalized-implants-in-a-rat-model
#7
Pooya Soltanzadeh, Amirreza Ghassemi, Manabu Ishijima, Miyuki Tanaka, Wonhee Park, Chika Iwasaki, Makoto Hirota, Takahiro Ogawa
STATEMENT OF PROBLEM: Despite its clinical benefits, the immediate loading protocol might have a higher risk of implant failure than the regular protocol. Ultraviolet (UV) photofunctionalization is a novel surface enhancement technique for dental implants. However, the effect of photofunctionalization under loading conditions is unclear. PURPOSE: The purpose of this animal study was to evaluate the effect of photofunctionalization on the biomechanical quality and strength of osseointegration under loaded conditions in a rat model...
February 17, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28222128/what-do-sales-data-tell-us-about-implant-survival
#8
Rudolf Seemann, Alexander Jirku, Florian Wagner, Arno Wutzl
OBJECTIVE: The aim of this study was to evaluate the influence of implant diameter, length and shape on a surrogate parameter of implant survival; i.e. the implant return rate in a big data analysis. MATERIALS AND METHODS: A retrospective study was conducted and the factors influencing the success rates of 69,377 sold implants over a seven-year period were evaluated. The osseointegration program of a reseller provides reliable data of a single country. Implant loss rates were investigated using logistic regression models and regressed by implant type, diameter, and length...
2017: PloS One
https://www.readbyqxmd.com/read/28218496/functional-analysis-of-bioactivated-surfaces
#9
Selgai Haidari, Marko Boskov, Ulrike Schillinger, Klaus-Dietrich Wolff, Christian Plank, Andreas Kolk
Common scaffold surfaces, such as titanium, can have side effects, e.g., infections, cytotoxicity, impaired osseointegration or low regeneration rates for bone tissue. These effects lead to poor implant integration or even implant loss. Therefore, bioactive implants are promising instruments in tissue regeneration. Osteoinductive elements, such as growth factors and anti-infectives, support wound healing and bone growth and thereby enable faster osseointegration, even in elderly patients. In this study, titanium surfaces were coated with a poly-(D,L-lactide) (PDLLA) layer containing different concentrations of copolymer-protected gene vectors (COPROGs) to locally provide bone morphogenetic protein-2 (BMP-2) or activated anti-infective agents, such as chlorhexidine gluconate, triclosan and metronidazole, to prevent peri-implantitis...
February 20, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28218482/osteoblastic-differentiation-of-periodontal-ligament-stem-cells-on-non-stoichiometric-calcium-phosphate-and-titanium-surfaces
#10
L Winning, L Robinson, A R Boyd, I A El Karim, F T Lundy, B J Meenan
Bioactive materials offer particular clinical benefits in the field of dental implantology, where differentiation of stem cells towards an osteoblastic lineage is required for osseointegration and appropriate function of implants in vivo. The aim of this study was to evaluate the osteoblastic response of Stro-1+ve periodontal ligament stem cells (PDLSCs) to three well-characterised biomaterial surfaces: an abraded titanium surface (cpTi) control; a polycrystalline titanium surface, with both micro and nano-topography produced by radio frequency magnetron sputtering (TiTi); and the same surface incorporating a sputter deposited calcium phosphate coating (CaP-TiTi)...
February 20, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28218025/dental-implants-and-incisor-bridge-placement-in-a-dog
#11
Rocco E Mele, Anthony Caiafa, Gregori M Kurtzman
Veterinary dentistry has tended to follow the trends and advancements in the human dental field. As for any procedure performed on a patient, whether human or animal, an informed decision is based on the available evidence regarding treatment options. This is certainly true for the more involved treatments in veterinary dentistry which can include the disciplines of endodontics and dental implantology. A number of published case reports have been accepted by the specialty that endodontic therapy is indeed a predictable and a valuable service that can be offered to pet owners...
December 2016: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28213949/peri-implant-bone-remodeling-at-the-interface-of-three-different-implant-types-a-histomorphometric-study-in-mini-pigs
#12
Wenjuan Zhou, Sonja Kuderer, Zhonghao Liu, Christian Ulm, Xiaohui Rausch-Fan, Stefan Tangl
OBJECTIVES: The aim of this study was to perform a histomorphometric evaluation of the healing characteristics and jawbone remodeling processes in the peri-implant bone tissue of three commonly used implant surfaces, during the early weeks of osseointegration. MATERIAL AND METHODS: Dental implants with three different surfaces (anodically modified, hydroxyapatite (HA)-coated and machined) were inserted into the mandibular side-tooth region of twelve adult mini-pigs...
February 18, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28213101/additively-manufactured-metallic-porous-biomaterials-based-on-minimal-surfaces-a-unique-combination-of-topological-mechanical-and-mass-transport-properties
#13
F S L Bobbert, K Lietaert, A A Eftekhari, B Pouran, S M Ahmadi, H Weinans, A A Zadpoor
: Porous biomaterials that simultaneously mimic the topological, mechanical, and mass transport properties of bone are in great demand but are rarely found in the literature. In this study, we rationally designed and additively manufactured (AM) porous metallic biomaterials based on four different types of triply periodic minimal surfaces (TPMS) that mimic the properties of bone to an unprecedented level of multi-physics detail. Sixteen different types of porous biomaterials were rationally designed and fabricated using selective laser melting (SLM) from a titanium alloy (Ti-6Al-4V)...
February 14, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28212453/bone-morphogenetic-protein-2-hybridized-with-nano-anchored-oligonucleotides-on-titanium-implants-enhances-osteogenic-differentiation-in-vivo
#14
Florian Böhrnsen, Jennifer Rublack, Nelia Aeckerle, Anne Foerster, Bernd Schwenzer, Judith Reichert, Dieter Scharnweber, Henning Schliephake
PURPOSE: Previous in vitro studies have shown that DNA oligonucleotides (ODN) can be successfully used as anchor strands for the binding and retarded release of biologically active recombinant human bone morphogenetic protein 2 (rhBMP-2). The aim of the present study was to test the hypothesis that rhBMP-2 bound to the surface of titanium implants through hybridization with nano-anchored ODN strands is biologically active and can enhance the induction of osteogenic markers in peri-implant bone in vivo...
February 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28212452/bone-to-implant-contact-and-new-bone-formation-within-human-freeze-dried-bone-blocks-grafted-over-rabbit-calvaria
#15
Zvi Artzi, Karen Anavi-Lev, Avital Kozlovsky, Liat Chaushu, Frank Schwarz, Haim Tal
PURPOSE: To assess the extent of osseointegration with rough-surface implants and new bone formation (NBF) within human freeze-dried bone blocks (h-FDB) grafted over rabbit calvaria. MATERIALS AND METHODS: A total of 18 rectangular h-FDB blocks were stabilized bilaterally to the calvaria of nine New Zealand rabbits by two mini titanium screws each. A total of 18 rough-surface implants (5.0 × 6.0-mm) were placed, 9 simultaneously (immediate placement [IP]) on one side and 9 at 3 months after block grafting (delayed placement [DP]) on the contralateral side...
February 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28211288/imaging-evaluating-of-the-implant-bone-interface-an-in-vitro-radiographic-study
#16
M M Vidor, G S Liedke, M B Vizzotto, Hld da Silveira, P F da Silveira, C W Araujo, Hed da Silveira
OBJECTIVES: To analyze the diagnostic accuracy of conventional and digital radiographic images and the impact of digital filters in evaluating the bone/implant interface. METHODS: Titanium implants were inserted into 74 fresh bovine ribs blocks, 37 fitting tight to the bone walls (simulating the existence of osseointegration), and 37 with a gap of 0.125 mm (simulating a failure in the osseointegration process). Periapical radiographs were taken with conventional film and two phosphor-plate systems (Vista Scan and Express)...
February 17, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28208793/chitosan-recombinamer-layer-by-layer-coatings-for-multifunctional-implants
#17
Jeevan Prasaad Govindharajulu, Xi Chen, Yuping Li, Jose Carlos Rodriguez-Cabello, Mrinal Battacharya, Conrado Aparicio
The main clinical problems for dental implants are (1) formation of biofilm around the implant-a condition known as peri-implantitis and (2) inadequate bone formation around the implant-lack of osseointegration. Therefore, developing an implant to overcome these problems is of significant interest to the dental community. Chitosan has been reported to have good biocompatibility and anti-bacterial activity. An osseo-inductive recombinant elastin-like biopolymer (P-HAP), that contains a peptide derived from the protein statherin, has been reported to induce biomineralization and osteoblast differentiation...
February 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28207942/effect-of-ridge-preservation-for-early-implant-placement-is-there-a-need-to-remove-the-biomaterial
#18
Daniel S Thoma, Nadja Naenni, Goran I Benic, Fernando Munoz, Christoph H F Hämmerle, Ronald E Jung
AIM: to assess i) bone regeneration around implants placed early in sites with or without ridge preservation and i) if the bone substitute material (DBBM-C) has to be removed at implant placement MATERIALS AND METHODS: In eight beagle dogs, three sites were randomly assigned to ridge preservation (DBBM-C plus collagen matrix (CMX)) (two sites; RP) or spontaneous healing (1 site; SH). Four weeks later, in one of the RP sites, dental implants were placed without removing the DBBM-C (RP1), whereas in RP2 and SH sites all non-integrated DBBM-C and/or granulation tissue was removed before implant placement and concomitant GBR...
February 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28207597/implant-anchorage-in-the-nasopalatine-canal-for-the-rehabilitation-of-severely-atrophic-maxilla
#19
Pâmela Leticia Dos Santos, Gustavo Henrique Souza Silva, Raquel Damazia da Silva, Fernanda Rayssa Da Silva Pereira, Jéssica Lemos Gulinelli
PURPOSE: This study aimed to describe the clinical case of implant placement in the nasopalatine canal as an aid for atrophic maxilla rehabilitation. CASE REPORT: The surgical procedure was carried out in 2 stages, the first part consisted of a surgery to lift the maxillary sinus membrane associated with the xenogeneic bone placement and the second part consisted of the surgery for the implants placement, both under local anesthesia. A number of seven osseointegrated implants were placed in the maxilla, one was anchored in the nasopalatine canal region after having its neurovascular content emptied by means of the use of drill threads of the implant system...
February 14, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28196162/the-use-of-recombinant-human-platelet-derived-growth-factor-for-maxillary-sinus-augmentation
#20
Atsushi Kubota, Hector Sarmiento, Mohammed Saad Alqahtani, Arturo Llobell, Joseph P Fiorellini
The maxillary sinus augmentation procedure has become a predictable treatment to regenerate bone for implant placement. The purpose of this study was to evaluate the effect of recombinant human platelet-derived growth factor BB (rhPDGF-BB) combined with a deproteinized cancellous bovine bone graft for sinus augmentation. The lateral window approach was used for maxillary sinuses with minimal residual bone. After a healing period of 4 months, dental implants were placed and then restored following a 2-month osseointegration period...
March 2017: International Journal of Periodontics & Restorative Dentistry
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