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Josephine Mauskopf, Baudouin Standaert, Mark P Connolly, Anthony J Culyer, Louis P Garrison, Raymond Hutubessy, Mark Jit, Richard Pitman, Paul Revill, Johan L Severens
This report provides recommendations for budget holders and decision makers in high-, middle, and low-income countries requiring economic analyses of new vaccination programs to allocate scarce resources given budget constraints. ISPOR's Economic Evaluation of Vaccines Designed to Prevent Infectious Disease: Good Practices Task Force wrote guidelines for three analytic methods and solicited comments on them from external reviewers. Cost-effectiveness analyses use decision-analytic models to estimate cumulative changes in resource use, costs, and changes in quality- or disability-adjusted life-years attributable to changes in disease outcomes...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Erika P Berger, Chad M Johannes, Albert E Jergens, Karin Allenspach, Barbara E Powers, Yingzhou Du, Jonathan P Mochel, Leslie E Fox, Margaret L Musser
BACKGROUND: Gastrointestinal stromal tumors (GISTs) are uncommon intestinal neoplasms in the dog. Literature regarding adjunctive therapy for GISTs in dogs is sparse. High-risk GISTs in humans respond to tyrosine kinase inhibition in the adjuvant setting. OBJECTIVES: To review cases of toceranib phosphate use in dogs with GISTs and provide initial assessment of possible biological activity. A secondary aim was to evaluate patient and tumor characteristics for possible prognostic value...
October 11, 2018: Journal of Veterinary Internal Medicine
Lawrence Lau, Dimitrios Papanagnou, Elaine Smith, Crystal Waters, Elizabeth Teixeira, Xiao Chi Zhang
Resuscitative hysterotomy is a daunting and rarely performed procedure in the emergency department (ED). Given the paucity of clinical exposure to this intervention, resuscitative hysterotomy is an ideal opportunity for simulation-mediated deliberate practice. The authors propose a novel training program using a homegrown, realistic, simulation device as a means to practice resuscitative hysterotomy. Two high-fidelity, tissue-based task-trainer models were constructed and tested on a convenience sample of 14 emergency medicine (EM) residents...
2018: Advances in Simulation
Min Qi Wang, Alice F Yan, Ralph V Katz
Background: Inappropriate analysis and reporting of biomedical research remain a problem despite advances in statistical methods and efforts to educate researchers. Objective: To determine the frequency and severity of requests biostatisticians receive from researchers for inappropriate analysis and reporting of data during statistical consultations. Design: Online survey. Setting: United States. Participants: A randomly drawn sample of 522 American Statistical Association members self-identifying as consulting biostatisticians...
October 9, 2018: Annals of Internal Medicine
Rachel Ekaireb, Cyrus Ahalt, Rebecca Sudore, Lia Metzger, Brie Williams
OBJECTIVES: To investigate correctional healthcare providers' knowledge of and experience with advance care planning (ACP), their perspectives on barriers to ACP in correctional settings, and how to overcome those barriers. DESIGN: Qualitative. SETTING: Four prisons in 2 states and 1 large city jail in a third state. PARTICIPANTS: Correctional healthcare providers (e.g., physicians, nurses, social workers; N=24). RESULTS: Participants demonstrated low baseline ACP knowledge; 85% reported familiarity with ACP, but only 42% provided accurate definitions...
October 9, 2018: Journal of the American Geriatrics Society
Chukwudi Chiaghana, Christopher Giordano, Danielle Cobb, Terrie Vasilopoulos, Patrick J Tighe, Joshua W Sappenfield
BACKGROUND: In the 1990s, emergency medicine (EM) physicians were responsible for intubating about half of the patients requiring airway management in emergency rooms. Since then, no studies have characterized the airway management responsibilities in the emergency room. METHODS: A survey was sent via the Eastern Association for Surgery and Trauma and the Trauma Anesthesiology Society listservs, as well as by direct solicitation. Information was collected on trauma center level, geographical location, department responsible for intubation in the emergency room, department responsible for intubation in the trauma bay, whether these roles differed for pediatrics, whether an anesthesiologist was available "in-house" 24 hours a day, and whether there was a protocol for anesthesiologists to assist as backup during intubations...
October 8, 2018: Anesthesia and Analgesia
Micha Loebermann, Carlos Fritzsche, Hilte Geerdes-Fenge, Esther Heijnen, Daniel Kirby, Emil C Reisinger
Vaccination is an essential tool in reducing the impact of seasonal influenza infections. The viral strains responsible for seasonal outbreaks vary annually, and preventive vaccines have to be adapted accordingly. The aim of this study was to evaluate the safety, clinical tolerability and the antibody response to each of the three influenza vaccine antigens after vaccination with a cell-derived, trivalent, surface antigen, inactivated influenza vaccine (TIVc), as measured by single radial haemolysis (SRH) or haemagglutination inhibition (HI) assay in accordance with European Union licensing guidelines in place for years 2013/2014...
October 8, 2018: Infection
Michelle F Mottola, Margie H Davenport, Stephanie-May Ruchat, Gregory A Davies, Veronica Poitras, Casey Gray, Alejandra Jaramillo, Nick Barrowman, Kristi B Adamo, Mary Duggan, Ruben Barakat, Phil Chilibeck, Karen Fleming, Milena Forte, Jillian Korolnek, Taniya Nagpal, Linda Slater, Deanna Stirling, Lori Zehr
OBJECTIVE: The objective is to provide guidance for pregnant women, and obstetric care and exercise professionals, on prenatal physical activity. OUTCOMES: The outcomes evaluated were maternal, fetal, or neonatal morbidity or fetal mortality during and following pregnancy. EVIDENCE: Literature was retrieved through searches of Medline, EMBASE, PsycINFO, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Scopus and Web of Science Core Collection, CINAHL Plus with Full-text, Child Development & Adolescent Studies, ERIC, Sport Discus, ClinicalTrials...
October 5, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Jessie Pow, Ellen Stephenson, Mariët Hagedoorn, Anita DeLongis
Research indicates that perceived support availability is beneficial, with support available from the spouse particularly important for well-being. However, actual support mobilization has shown mixed associations with recipient well-being. The primary goal of the present study was to go beyond examining the effects of global perceptions of support on recipient outcomes. Instead, we examined the effects of several specific types of support that have been found to be important in the clinical literature. In this study, we followed both members of couples in which one partner was diagnosed with rheumatoid arthritis...
2018: Frontiers in Psychology
Kelsey Gangemi, Roxanne Dupuis, Elizabeth FitzGerald, Rosemary Frasso, Sara Solomon, Carolyn C Cannuscio
In Philadelphia, over 40% of youth are overweight or obese. The objective in this assessment was to learn about urban residents' perspectives regarding the local food environment and its impact on eating behaviors. Using photo-elicitation, 20 adolescents reflected on their food environments through photographs and corresponding interviews. Without specific prompting from interviewers, every participant raised concerns about their school food environments, which they commonly found to be unhealthy and unappealing...
October 4, 2018: Journal of School Nursing: the Official Publication of the National Association of School Nurses
Nancy E Lundebjerg, Laurie G Jacobs, Daniel E Trucil, Alanna C Goldstein, Debra Saliba
In July 2018, the Centers for Medicare & Medicaid Services (CMS) released its proposed Medicare Physician Fee Schedule rule for Calendar Year 2019 (MPFS2019). The proposal sets forth CMS recommended updates to Medicare payment policies, payment rates, and quality provisions for services provided in the next calendar year. From year to year, the rule also can serve as a vehicle for soliciting input on new payment proposals and changes to existing policies. Among the payment and quality proposals in the MPFS2019 proposal, CMS proposed extensive changes to Current Procedural Terminology (CPT) codes that are the framework for documentation and payment for office-based evaluation and management (E/M) services...
October 4, 2018: Journal of the American Geriatrics Society
Lavinia Barone, Andrea Carta, Yagmur Ozturk
To date, few studies have investigated the social-emotional functioning of planned lesbian families, wherein only one parent is the biological mother of the child. We examined if being a biological versus non-biological mother plays a role in planned lesbian couple functioning and mother-infant play interactions. The present study analyzes the attachment state of mind, couple alliance, parenting stress, and emotional availability in a sample of 40 mothers (20 biological and 20 non-biological). The results showed that mothers' life-long attachment experiences and related mental states of mind, rather than biological relatedness between the parent and child, matter in a mother and child's emotional involvement in parent-child interaction...
October 3, 2018: Attachment & Human Development
Ilhan Dalci, Hasan Ozyapici
Hospitals, which are mainly capital intensive, require large amounts of financial resources to render high-quality services. Accordingly, health care managers and policy makers should take into account the level of debt in managing working capital. This study, therefore, aims to explore whether the financial leverage moderates the relationship between the working capital and profitability for the publicly-listed European Hospitals. The data set including 52 hospitals with 468 observations was solicited from the ORBIS...
September 24, 2018: Health Policy
Afton M Koball, Dylan J Jester, Marisa A Pruitt, Rebecca V Cripe, Jill J Henschied, Sarah Domoff
BACKGROUND: Support after bariatric surgery is critical. Access to bariatric support groups is sometimes challenging, leading people to seek support on social media platforms like Facebook. Given the ubiquity of recommendations solicited and provided on Facebook regarding nutrition and bariatric surgery, understanding the content and accuracy of these posts is important. OBJECTIVES: The primary aim of the present study was to describe the content of nutrition-related information sought on bariatric Facebook support groups/pages...
August 28, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Sarah Dababnah, Wendy E Shaia, Karen Campion, Helen M Nichols
Black children with autism spectrum disorder (ASD) are diagnosed later than their White peers, are more likely to be misdiagnosed, and are less likely to receive early intervention services or a developmental evaluation by three years old. Using a grounded theory approach, we solicited the perspectives of parents and other primary caregivers of Black children with ASD on barriers and facilitators to ASD screening and referrals in primary care. A socioeconomically diverse sample of 22 female caregivers participated...
October 2018: Intellectual and Developmental Disabilities
Mary Regan, Mary B Engler, Bernice Coleman, Sandra Daack-Hirsch, Kathleen A Calzone
PURPOSE: To establish the knowledge needed to integrate the multiple branches of omics into nursing research to accelerate achieving the research recommendations of the Genomic Nursing Science Blueprint. METHODS: The creation of the Genomic Knowledge Matrix occurred in three phases. In phase 1, the Omics Nursing Science and Education Network (ONSEN) Education Workgroup completed an evidence, bioinformatics, and technology review to inform the components of the Matrix...
October 1, 2018: Journal of Nursing Scholarship
Michael C Dewan, Ronnie E Baticulon, Abbas Rattani, James M Johnston, Benjamin C Warf, William Harkness
OBJECTIVE: The presence and capability of existing pediatric neurosurgical care worldwide is unknown. The objective of this study was to solicit the expertise of specialists to quantify the geographic representation of pediatric neurosurgeons, access to specialist care, and equipment and training needs globally. METHODS: A mixed-question survey was sent to surgeon members of several international neurosurgical and general pediatric surgical societies via a web-based platform...
October 2018: Neurosurgical Focus
Aitana Juan-Giner, Marie Tchaton, Jean-Paul Jemmy, Aboubacar Soumah, Yap Boum, Elisabetta Maria Faga, Mohamed Cisse, Rebecca F Grais
BACKGROUND: As part of the ring vaccination trial in Guinea, Front Line Workers were invited to participate in a sub-study to provide additional information on the immunogenicity and safety of rVSVΔG/ZEBOV-GP. Here we summarize the information on the safety follow-up. METHODS: An open-label, non-randomized, immunogenicity evaluation of one dose of rVSVΔG/ZEBOV-GP was conducted in Conakry, Guinea between March 2015 and July 2016. Front-line workers refusing vaccination were invited to participate as a control group...
September 25, 2018: Vaccine
Yosra Cherni, Annie Pouliot Laforte, Audrey Parent, Pierre Marois, Mickael Begon, Laurent Ballaz
BACKGROUND AND PURPOSE: The strategies for walking fast have never been reported in children with cerebral palsy who walk in crouch gait. This study aimed to assess to what extent children who walk in crouch gait are able to increase their gait speed and to report the corresponding three-dimensional kinematic adaptations. METHODS: Eleven children and adolescents (aged between 7 and 17 years) with bilateral cerebral palsy, who walk in crouch gait, were asked to walk at their self-selected comfortable speed and then as fast as possible without running...
September 28, 2018: Disability and Rehabilitation
Logan C DeBord, Viraat Patel, Tara L Braun, Harry Dao
Social media encompasses multiple sites for online communication that reach a large proportion of the global population. While the increase in number of publications investigating dermatology content on social media has paralleled the growth of social media in the past decade, there has not yet been an extensive review of past literature on this topic. Our objective is to summarize and analyze publications on the role of social media within the field of dermatology. Social media is frequently used by patients to solicit advice related to cutaneous concerns and even when seeking out a dermatologist, but it is underutilized among both clinicians marketing their practices and academicians collaborating with colleagues in the field...
September 28, 2018: Journal of Dermatological Treatment
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