Read by QxMD icon Read

General knowledge

May A Massoud, Arine Kazarian, Ibrahim Alameddine, Mahmoud Al-Hindi
The reuse of treated wastewater, whether direct or indirect, can raise public concerns as a result of the overall risk perception. As such, community acceptance plays a significant role in the implementation of alternative water systems. Public attitudes towards water reuse are highly influenced by perceived health risk, religious prohibition, political issues, and the degree of human contact with recycled water. In most of the Mediterranean countries, wastewater is reused to different extents either within planned or unplanned schemes...
August 18, 2018: Environmental Monitoring and Assessment
M Aidalina, A S J Syed Mohamed
INTRODUCTION: This review aimed to summarise the trend of mammogram screening uptake published in local studies between years 2006 and 2015 among the Malaysian women aged 40 years and above, and identify the associated factors and barriers, as well as discuss limitations of the studies and research gaps. METHODS: A systematic review was conducted on breast cancer screening studies among Malaysian women, published between January 2006 and December 2015. Online databases were searched using keywords: "mammogram", "mammography", "uptake", "breast cancer screening" and "Malaysia"...
August 2018: Medical Journal of Malaysia
Chao Song, Xun Shi, Yanchen Bo, Jinfeng Wang, Yong Wang, Dacang Huang
BACKGROUND: Pediatric hand, foot, and mouth disease (HFMD) has generally been found to be associated with climate. However, knowledge about how this association varies spatiotemporally is very limited, especially when considering the influence of local socioeconomic conditions. This study aims to identify multi-sourced HFMD environmental factors and further quantify the spatiotemporal nonstationary effects of various climate factors on HFMD occurrence. METHODS: We propose an innovative method, named spatiotemporally varying coefficients (STVC) model, under the Bayesian hierarchical modeling framework, for exploring both spatial and temporal nonstationary effects in climate covariates, after controlling for socioeconomic effects...
August 9, 2018: Science of the Total Environment
Adriana Lucía-Sanz, Jacobo Aguirre, Susanna Manrubia
Multipartite viruses have a segmented genome encapsidated in different viral particles that, in principle, propagate independently. Current empirical knowledge on the molecular, ecological and evolutionary features underlying the very existence of multipartitism is fragmented and puzzling. Although it is generally assumed that multipartitism is viable only when propagation occurs at high multiplicity of infection, evidence indicates that severe population bottlenecks are common. Mathematical models aimed at describing the dynamics of multipartite viruses typically assign an advantage to the multipartite form to compensate for the cost of high multiplicity of infection...
August 16, 2018: Current Opinion in Virology
M B K C Dayasiri, S F Jayamanne, C Y Jayasinghe
BACKGROUND: The burden of poisoning among children is largely underexplored in rural Sri Lanka. This study describes the patterns of demographic characteristics, poison related factors, clinical management and outcome following acute poisoning among children (9 months- 12 years) in rural Sri Lanka. METHOD: This hospital based multi-center study included Anuradhapura Teaching hospital, Polonnaruwa District General hospital, and 34 regional hospitals within Regional Director of Health Services in North Central province of Sri Lanka...
August 18, 2018: BMC Pediatrics
Kathryn Berzins, John Baker, Mark Brown, Rebecca Lawton
BACKGROUND: Establishing patient safety priorities in psychiatry has received less international attention than in other areas of health care. This study aimed to identify safety issues as described by people in the United Kingdom identifying as mental health service users, carers and professionals. METHODS: A cross-sectional online survey was distributed via social media. Identified safety issues were mapped onto the Yorkshire Contributory Factors Framework (YCFF) which categorizes factors that contribute to patient safety incidents in general hospital settings...
August 17, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
Johanna F Lindahl, Jarrah Young, Amanda Wyatt, Mary Young, Robyn Alders, Brigitte Bagnol, Augustino Kibaya, Delia Grace
Poultry are important for many poor households in developing countries, but there are many constraints to poultry production, including disease. One of the most important diseases of chickens is Newcastle disease (ND). Even though there are effective vaccines against this disease available in most countries, uptake by small-scale poultry keepers is often low. In this study, two areas in Kenya and Tanzania were studied, where some villages had received additional support to get vaccination and other villages had not...
August 17, 2018: Tropical Animal Health and Production
Erika A Waters, Caitlin Biddle, Kimberly A Kaphingst, Elizabeth Schofield, Marc T Kiviniemi, Heather Orom, Yuelin Li, Jennifer L Hay
BACKGROUND: Health literacy and numeracy influence many health-related behaviors and outcomes. Health literacy and numeracy have been assessed objectively and subjectively, but interrelationships among the measures and the consistency of their association with health knowledge have not been examined. OBJECTIVE: To increase understanding of the structure and interrelations among objective and subjective health literacy and numeracy and how these constructs relate to knowledge of risk factors of two major diseases...
August 17, 2018: Journal of General Internal Medicine
Christina M Vanden Bosch der Nederlanden, Che'Renee Zaragoza, Angie Rubio-Garcia, Evan Clarkson, Joel S Snyder
Our world is a sonically busy place and we use both acoustic information and experience-based knowledge to make sense of the sounds arriving at our ears. The knowledge we gain through experience has the potential to shape what sounds are prioritized in a complex scene. There are many examples of how visual expertise influences how we perceive objects in visual scenes, but few studies examine how auditory expertise is associated with attentional biases toward familiar real-world sounds in complex scenes. In the current study, we investigated whether musical expertise is associated with the ability to detect changes to real-world sounds in complex auditory scenes, and whether any such benefit is specific to musical instrument sounds...
August 17, 2018: Psychological Research
Axel Schick, Christina Sandig, Anja Krause, Peter R Hobson, Stefan Porembski, Pierre L Ibisch
Growing levels of uncertainty and vulnerability generated by land use conversion and climate change set demands on local communities and national institutions to build synergies between the diverse array of knowledge systems in order to provide policy makers and practitioners with the best available information to decide what urgent actions must be taken. Science policy arenas and agreements such as the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) and the Convention on Biological Diversity (CBD) recognize the importance of different types of knowledge and the need for broad stakeholder involvement, yet the use of indigenous and local knowledge (ILK) in environmental decision-making processes is still underdeveloped...
August 17, 2018: Environmental Management
Karen A Schlauch, Doina Kulick, Krishnamurthy Subramanian, Kenny L De Meirleir, András Palotás, Vincent C Lombardi
BACKGROUND/OBJECTIVES: Obesity is an important risk factor for the development of diseases such as diabetes mellitus, hypertension, and dyslipidemia; however, a small number of individuals with long-standing obesity do not present with these cardiometabolic diseases. Such individuals are referred to as metabolically healthy obese (MHO) and potentially represent a subgroup of the general population with a protective genetic predisposition to obesity-related diseases. We hypothesized that individuals who were metabolically healthy, but significantly obese (BMI ≥ 35 kg/m2 ) would represent a highly homogenous subgroup, with which to investigate potential genetic associations to obesity...
August 17, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Courtney P Williams, Kelly M Kenzik, Andres Azuero, Grant R Williams, Maria Pisu, Karina I Halilova, Stacey A Ingram, Supriya K Yagnik, Andres Forero, Smita Bhatia, Gabrielle B Rocque
BACKGROUND: National Comprehensive Cancer Network (NCCN) guideline-based treatment is a marker of high-quality care. The impact of guideline discordance on cost and health care utilization is unclear. MATERIALS AND METHODS: This retrospective cohort study of Medicare claims data from 2012 to 2015 included women age ≥65 with stage I-III breast cancer receiving care within the University of Alabama at Birmingham Cancer Community Network. Concordance with NCCN guidelines was assessed for treatment regimens...
August 17, 2018: Oncologist
Lauren M Fletcher, Javier Atalah, Barrie M Forrest
The colonial ascidian Didemnum vexillum is a high-profile marine invader, with a geographically widespread distribution after introductions to several temperate regions. D. vexillum has been the focus of several eradication and control programmes globally and the need for specific biological knowledge that relates to establishment processes, persistence, impacts and potential for spread remains. The present study describes temporal patterns of D. vexillum percent cover on experimental substrates over 1.5-years in relation to seasonality of substratum availability, in conjunction with key physical (i...
August 7, 2018: Marine Environmental Research
Mehrdad Farzandipour, Ehsan Nabovati, Soheila Saeedi, Esmaeil Fakharian
BACKGROUND AND OBJECTIVE: Musculoskeletal disorders (MSDs) are one of the most important causes of disability with a high prevalence. The accurate and timely diagnosis of these disorders is often difficult. Clinical decision support systems (CDSSs) can help physicians to diagnose diseases quickly and accurately. Given the ambiguous nature of MSDs, fuzzy logic can be helpful in designing the CDSSs knowledge bases. The present study aimed to review the studies on fuzzy CDSSs to diagnose MSDs...
September 2018: Computer Methods and Programs in Biomedicine
Sidra Zafar, M A Rehman Siddiqui
BACKGROUND: Sub-retinal abscess as the presenting feature in the setting of endogenous fungal endophthalmitis is extremely infrequent. Immunodeficiency states are major predisposing risk factors. To the best of our knowledge, this is the first case report of Candida sub-retinal abscess as initial presentation in an immunocompetent patient. CASE PRESENTATION: A 32-year old, generally fit and well, female presented to us with gradually deteriorating vision in her right eye...
August 17, 2018: BMC Research Notes
Edward Baker, Andreas Xyrichis, Christine Norton, Philip Hopkins, Geraldine Lee
BACKGROUND: Major Trauma remains a leading cause of mortality and morbidity worldwide. Blunt Thoracic Injury (BTI) accounts for > 15% of United Kingdom (UK) trauma admissions and is consistently associated with respiratory related complications that include pneumonia and respiratory failure. Despite this, it is unclear in current clinical practice how BTI impacts on the recovering trauma patients after discharge from hospital. This study aimed to investigate the state of knowledge on the impact of BTI on the long-term outcomes and health-related quality of life (HRQoL)...
August 17, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Fabiën N Belle, Rahel Kasteler, Christina Schindera, Murielle Bochud, Roland A Ammann, Nicolas X von der Weid, Claudia E Kuehni
BACKGROUND: Glucocorticoids can lead to weight gain during cancer treatment, but to the authors' knowledge, little is known regarding their long-term effects in childhood cancer survivors (CCS). METHODS: As part of the Swiss Childhood Cancer Survivor Study, the authors sent a questionnaire to CCS aged <21 years at diagnosis who were residing in Switzerland, had survived ≥5 years, and were aged 15 to 45 years at the time of the survey. Cumulative doses of glucocorticoids were assessed from medical records and study protocols and body mass index was calculated from self-reported height and weight at the time of the survey...
August 17, 2018: Cancer
Ali Nawaz, Witoon Purahong, Robert Lehmann, Martina Herrmann, Kai Uwe Totsche, Kirsten Küsel, Tesfaye Wubet, François Buscot
Although fungi play important roles in biogeochemical cycling in aquatic ecosystems and have received a great deal of attention, much remains unknown about the living fractions of fungal communities in aquifers of the terrestrial subsurface in terms of diversity, community dynamics, functional roles, the impact of environmental factors and presence of fungal pathogens. Here we address this gap in knowledge by using RNA-based high throughput pair-end illumina sequencing analysis of fungal internal transcribed spacer (ITS) gene markers, to target the living fractions of groundwater fungal communities from fractured alternating carbonate-/siliciclastic-rock aquifers of the Hainich Critical Zone Exploratory...
July 28, 2018: Water Research
Gert Peters, Jo Maertens, Jeroen Lammertyn, Marjan De Mey
Metabolic engineering increasingly depends upon RNA technology to customly rewire the metabolism to maximize production. To this end, pure riboregulators allow dynamic gene repression without the need of a potentially burdensome coexpressed protein like typical Hfq binding small RNAs and clustered regularly interspaced short palindromic repeats technology. Despite this clear advantage, no clear general design principles are available to de novo develop repressing riboregulators, limiting the availability and the reliable development of these type of riboregulators...
August 17, 2018: PLoS Computational Biology
Eugenio Hardy, Anette Hardy-Sossa, Carlos Fernandez-Patron
Matrix metalloproteinase-2 (MMP-2) cleaves a broad spectrum of substrates including extracellular matrix components (responsible for normal tissue remodeling) and cytokines (modulators of the inflammatory response to physiological insults such as tissue damage). MMP-2 expression is elevated in many pathologies (e.g., myocardial infarction, hypertensive heart disease, inflammation) where tissue remodeling and inflammatory responses are perturbed. Thus, it has generally been assumed that blockade of MMP-2 activity will yield therapeutic effects...
August 17, 2018: American Journal of Physiology. Heart and Circulatory Physiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"