Edvard H Sagelv, Andrea Casolo, Anne Elise Eggen, Kim Arne Heitmann, Kristoffer R Johansen, Maja-Lisa Løchen, Ellisiv B Mathiesen, Bente Morseth, Inger Njølstad, John O Osborne, Karianne Hagerupsen, Sigurd Pedersen, Tom Wilsgaard
OBJECTIVE: To examine the dose-response association between estimated cardiorespiratory fitness (eCRF) and risk of myocardial infarction (MI). PATIENTS AND METHODS: Adults who attended Tromsø Study surveys 4-6 (Janurary 1,1994-December 20, 2008) with no previous cardiovascular disease were followed up through December 31, 2014 for incident MI. Associations were examined using restricted cubic splines Fine and Gray regressions, adjusted for education, smoking, alcohol, diet, sex, adiposity, physical activity, study survey, and age (timescale) in the total cohort and subsamples with hyperlipidemia (n=2956), hypertension (n=8290), obesity (n=5784), metabolic syndrome (n=1410), smokers (n=3823), and poor diet (n=3463) and in those who were physically inactive (n=6255)...
February 2024: Mayo Clinic Proceedings. Innovations, Quality & Outcomes