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https://www.readbyqxmd.com/read/30107811/the-effects-of-bone-marrow-mononuclear-cell-transplantation-on-the-quality-of-life-of-children-with-cerebral-palsy
#1
Thanh Liem Nguyen, Hoang Phuong Nguyen, Trung Kien Nguyen
BACKGROUND: Quality of life (QOL) is an important factor in evaluating the effectiveness of treatment in children with cerebral palsy (CP). The aim of this study was to evaluate the effects of autologous bone marrow mononuclear cells (BM MNCs) on the QOL of children with CP. METHODS: From December 2015 to December 2016, 30 children with CP aged from 2 to 15 years received two intrathecal infusions of BM MNCs, one at baseline and the other 3 months later, at Vinmec International Hospital...
August 14, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/30075529/sustained-disconnection-in-sensorimotor-pathways-results-in-poor-motor-function-outcome-in-a-term-infant-after-severe-white-matter-injury-a-case-report
#2
Sunhan Son, Si Hyun Kang, Na Mi Lee, Don-Kyu Kim, Kyung Mook Seo, Hee Joon Ro
INTRODUCTION: We report a case of an infant with severe white matter injury (WMI), which was serially evaluated using diffusion tensor imaging (DTI). CASE PRESENTATION: A male infant showed decreased muscle tone and weak breathing. A brain magnetic resonance imaging (MRI) 10 days after birth (first study) revealed diffuse microhemorrhages and encephalomalacia. DTI revealed lack of reconstruction of corticospinal tract (CSTs), minimal reconstruction of medial lemniscus, and related thalamocortical pathways (MLs) from the brain stem to the internal capsule level on the left side...
August 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30062917/effect-of-ketogenic-diet-on-motor-functions-and-daily-living-activities-of-children-with-multidrug-resistant-epilepsy-a-prospective-study
#3
Duygu Çubukçu, Orkide Güzel, Nur Arslan
AIMS: To investigate the effect of ketogenic diet on motor function and daily living activities in children with epilepsy. METHODS: A total of 62 children (median age 5.0 years) were enrolled. Motor function was assessed using the Gross Motor Function Measure (GMFM), and daily living activities and cognitive functions were assessed using the Functional Independence Measure (WeeFIM) before treatment and 3, 6, and 12 months after ketogenic diet treatment. RESULTS: Significant improvement in total GMFM and WeeFIM scores ( P < ...
July 31, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/30029069/sense-of-autonomy-and-daily-and-scholastic-functioning-among-children-with-cerebral-palsy
#4
Dina Elad, Sharon Barak, Tamar Silberg, Amichai Brezner
BACKGROUND: There is growing evidence that children's sense of autonomy is an important psychological need closely linked with the development of self-esteem and motivation. Among children with physical disabilities, motor or cognitive limitations may negatively affect child's sense of autonomy (CSA) and competency. PURPOSE: To examine how sense of autonomy among children with cerebral palsy (CP) directly and indirectly relates to their activity of daily living (ADL) and scholastic performance...
September 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/30028064/reference-centiles-for-the-gross-motor-function-measure-and-identification-of-therapeutic-effects-in-children-with-cerebral-palsy
#5
Ibrahim Duran, Christina Stark, Kyriakos Martakis, Stefanie Hamacher, Oliver Semler, Eckhard Schoenau
RATIONALE, AIMS, AND OBJECTIVES: Children with cerebral palsy (CP) can show an increase in gross motor function until the age of 9 to 10 years under the standard of care. Additionally, the motor development can have large individual fluctuations. Therefore, in clinical setting, it is not trivial to estimate the effect of an additional therapeutic intervention at this age interval. The study aim was to develop a method which allows quantification of the gross motor function changes over 6 months of the individual child with CP...
July 20, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29972120/-effect-of-suspension-exercise-training-on-motor-and-balance-functions-in-children-with-spastic-cerebral-palsy
#6
Jun Wang, Yong-Bin Lang, Jiang-Hua DU, Zhen Chen, Deng-Na Zhu, Yong Zhang, Meng-Yue Li, Pei Tong
OBJECTIVE: To study the effect of suspension exercise training on motor and balance functions in children with spastic cerebral palsy. METHODS: A total of 97 children with spastic cerebral palsy were randomly divided into an observation group with 49 children and a control group with 48 children. Both groups were given routine rehabilitation training, and the children in the observation group were given suspension exercise training in addition. The scores of the D and E domains of the 88-item version of the Gross Motor Function Measure (GMFM-88) and Berg Balance Scale (BBS) were recorded before treatment and at 1, 3, and 6 months after treatment...
June 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29972001/-effects-of-intradermal-needling-on-core-muscle-stability-in-children-with-cerebral-palsy-a-clinical-comparative-study
#7
Tengche Qi, Chunnan Wang
OBJECTIVE: To observe the effects of rehabilitation training (RT) combined with intradermal needling, RT combined with acupuncture and RT alone on core muscle stability in children with cerebral palsy, and to explore the superior therapy to improve core muscle stability in children with cerebral palsy. METHODS: A total of 120 children with cerebral palsy aged from 2 to 4 years old were randomly divided into a RT and intradermal needling group (group A), a RT and acupuncture group (group B) and a RT group (group C), 40 cases in each one...
June 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29960742/o-100-does-one-leg-standing-duration-have-relation-with-gmfm-scores-and-stability-in-stance-phase-for-hemiplegic-children
#8
G Ertürk, N E Akalan, H Evrendilek, G Karaca, F Bilgili
No abstract text is available yet for this article.
June 25, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29773349/robot-assisted-training-using-hybrid-assistive-limb%C3%A2-for-cerebral-palsy
#9
Mayumi Matsuda, Nobuaki Iwasaki, Yuki Mataki, Hirotaka Mutsuzaki, Kenichi Yoshikawa, Kazushi Takahashi, Keiko Enomoto, Kumiko Sano, Aoi Kubota, Tomohiro Nakayama, Junko Nakayama, Haruka Ohguro, Masafumi Mizukami, Kazuhide Tomita
PURPOSE: The Hybrid Assistive Limb® (HAL®, CYBERDYNE) is a wearable robot that provides assistance to a patient while they are walking, standing, and performing leg movements based on the wearer's intended movement. The effect of robot-assisted training using HAL® for cerebral palsy (CP) is unknown. Therefore, we assessed the effect of robot-assisted training using HAL® on patients with CP, and compared walking and gross motor abilities between pre-intervention and post-intervention...
September 2018: Brain & Development
https://www.readbyqxmd.com/read/29771161/casting-protocols-following-bont-a-injections-to-treat-spastic-hypertonia-of-the-triceps-surae-in-children-with-cerebral-palsy-and-equinus-gait-a-randomized-controlled-trial
#10
Barbara Kelly, Marilyn MacKay-Lyons, Susan Berryman, Joe Hyndman, Ellen Wood
AIM: To study the effects of single versus serial casting post-Botulinum toxin A (BoNT-A) injections on hypoextensibility of triceps surae in children, 2-7 years old, with cerebral palsy and equinus gait. METHODS: A randomized, stratified, parallel, two-group trial was conducted at a pediatric health center with assessments at baseline, precast, postcast and, 1-, 2-, and 6-month follow-ups. One week following BoNT-A injections into triceps surae muscle, a single below-knee cast (n = 10) or 3 serial casts (n = 10) were applied for 3 weeks...
May 17, 2018: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/29765882/relationship-between-functional-level-and-muscle-thickness-in-young-children-with-cerebral-palsy
#11
Yeo Reum Choe, Joo Sup Kim, Kee Hoon Kim, Tae Im Yi
Objective: To investigate the relationship between functional level and muscle thickness (MT) of the rectus femoris (RF) and the gastrocnemius (GCM) in young children with cerebral palsy (CP). Methods: The study participants were comprised of 26 children (50 legs) with spastic CP, aged 3-6 years, and 25 age-matched children with typical development (TD, 50 legs). The MT of the RF, medial GCM, and lateral GCM was measured with ultrasound imaging. The functional level was evaluated using the Gross Motor Function Measurement-88 (GMFM-88), Gross Motor Function Classification System (GMFCS), and based on the mobility area of the Korean version of the Modified Barthel Index (K-MBI)...
April 2018: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29714626/factors-associated-with-enhanced-gross-motor-progress-in-children-with-cerebral-palsy-a-register-based-study
#12
Gunfrid V Størvold, Reidun B Jahnsen, Kari Anne I Evensen, Ulla K Romild, Grete H Bratberg
AIM: To examine associations between interventions and child characteristics; and enhanced gross motor progress in children with cerebral palsy (CP). METHODS: Prospective cohort study based on 2048 assessments of 442 children (256 boys, 186 girls) aged 2-12 years registered in the Cerebral Palsy Follow-up Program and the Cerebral Palsy Register of Norway. Gross motor progress estimates were based on repeated measures of reference percentiles for the Gross Motor Function Measure (GMFM-66) in a linear mixed model...
May 1, 2018: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/29714066/effect-of-ankle-foot-orthoses-on-gait-balance-and-gross-motor-function-in-children-with-cerebral-palsy-a-systematic-review-and-meta-analysis
#13
Mael Lintanf, Jean-Sébastien Bourseul, Laetitia Houx, Mathieu Lempereur, Sylvain Brochard, Christelle Pons
OBJECTIVE: To determine the effects of ankle-foot orthoses (AFOs) on gait, balance, gross motor function and activities of daily living in children with cerebral palsy. DATA SOURCES: Five databases were searched (Pubmed, Psycinfo, Web of Science, Academic Search Premier and Cochrane Library) before January 2018. REVIEW METHODS: Studies of the effect of AFOs on gait, balance, gross motor function and activities of daily living in children with cerebral palsy were included...
April 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29704186/immersive-virtual-reality-to-improve-walking-abilities-in-cerebral-palsy-a-pilot-study
#14
Chiara Gagliardi, Anna Carla Turconi, Emilia Biffi, Cristina Maghini, Alessia Marelli, Ambra Cesareo, Eleonora Diella, Daniele Panzeri
Immersive virtual reality (IVR) offers new possibilities to perform treatments in an ecological and interactive environment with multimodal online feedbacks. Sixteen school-aged children (mean age 11 ± 2.4 years) with Bilateral CP-diplegia, attending mainstream schools were recruited for a pilot study in a pre-post treatment experimental design. The intervention was focused on walking competences and endurance and performed by the Gait Real-time Analysis Interactive Lab (GRAIL), an innovative treadmill platform based on IVR...
April 27, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29675072/phenol-versus-botulinum-toxin-a-injection-in-ambulatory-cerebral-palsy-spastic-diplegia-a-comparative-study
#15
Nitesh Gonnade, Vaibhav Lokhande, Mohammed Ajij, Anil Gaur, Kamalakant Shukla
The aim of this study is to compare the treatment effectiveness of botulinum toxin type A (BTX-A) and phenol blocks in the management of lower limb spasticity and to measure improvement in gross motor functional outcome in children with cerebral palsy (CP). This is a hospital-based prospective, noncontrolled randomized study that took place in a tertiary care center. A total of 61 ambulatory children with CP spastic diplegia, aged from 4 to 10 years, were randomly divided into two groups and included in this study...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29663838/discriminant-ability-and-criterion-validity-of-the-trunk-impairment-scale-for-cerebral-palsy
#16
Sílvia Leticia Pavão, Davi Adiwardana Maeda, Carolina Corsi, Mariana Martins Dos Santos, Carolina Souza N da Costa, Ana Carolina de Campos, Nelci Adriana Cicuto Ferreira Rocha
AIMS: To compare the performance of children with mild and moderate-to-severe cerebral palsy (CP) on the Trunk Impairment Scale (TIS), Gross Motor Function Measure (GMFM), and on center-of-pressure variables; to establish the discriminant ability of these tools to predict severity of motor impairment in CP; and to investigate the criterion validity of the TIS. METHODS: Children with mild (n = 18, 11 males, 7 females, mean age = 9.5 ± 2.9 years, Gross Motor Function Classification System I-II) and moderate-to-severe (n = 18, 11 males, 7 females, mean age = 9...
April 17, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29652201/trunk-control-and-functionality-in-children-with-spastic-cerebral-palsy
#17
Gulce Kallem Seyyar, Bahar Aras, Ozgen Aras
PURPOSE: To investigate the relationship between trunk control in sitting and functionality in children with spastic cerebral palsy (CP). METHODS: Fifty-eight children with spastic CP were included in the study. Functional abilities were evaluated with the Gross Motor Function Measurement-88 (GMFM-88) and the Pediatric Evaluation of Disability Inventory Functional Skills domain (PEDI-FSD). Trunk control in sitting was tested with the Trunk Control Measurement Scale (TCMS) and the Trunk Impairment Scale (TIS)...
April 13, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29650492/robotically-driven-orthoses-exert-proximal-to-distal-differential-recovery-on-the-lower-limbs-in-children-with-hemiplegia-early-after-acquired-brain-injury
#18
Elena Beretta, Erika Molteni, Emilia Biffi, Roberta Morganti, Paolo Avantaggiato, Sandra Strazzer
Robotically-driven orthoses (RDO) are promising for treating gait impairment in children with hemiplegia after acquired brain injury (ABI). Despite this, existing literature on the employment of RDO in ABI is scanty, and cohorts' age spans throughout the adult age, with no specific focus on the developmental age. We aim to compare a treatment solely based on conventional physiotherapy (CP) with a program combining RDO training with CP, and to examine the effect of time following ABI on recovery. A prospective two-cohorts study was conducted in a rehabilitation hospital...
July 2018: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29628361/relationship-between-habitual-physical-activity-motor-capacity-and-capability-in-children-with-cerebral-palsy-aged-4-5-years-across-all-functional-abilities
#19
Piyapa Keawutan, Kristie L Bell, Stina Oftedal, Peter S W Davies, Robert S Ware, Roslyn N Boyd
BACKGROUND: Children with cerebral palsy (CP) have lower habitual physical activity (HPA) than their typically developing peers. There are limited studies of HPA in young children with CP under the age of 5 years. OBJECTIVE: To investigate the relationships between HPA, sedentary time, motor capacity and capability in children with CP aged 4-5 years. METHODS: Sixty-seven participants were classified using Gross Motor Function Classification System (GMFCS), assessed for motor capacity using Gross Motor Function Measure (GMFM) and wore accelerometers for three days to measure HPA and sedentary time...
April 3, 2018: Disability and Health Journal
https://www.readbyqxmd.com/read/29510955/effect-of-botulinum-toxin-type-a-treatment-in-children-with-cerebral-palsy-sequential-physical-changes-for-3-months-after-the-injection
#20
Mayumi Matsuda, Kazuhide Tomita, Arito Yozu, Tomohiro Nakayama, Jyunko Nakayama, Haruka Ohguro, Nobuaki Iwasaki
PURPOSE: This study investigated the sequential physical changes after botulinum toxin type A (BTX-A) injected in children with cerebral palsy. METHODS: Nine children with cerebral palsy were included. Measurements were performed before treatment and 4 weeks, 8 weeks, and 12 weeks after treatment. We used video-recorded gait in the sagittal plane. The maximum flexion and extension angles of the hip, knee and ankle joints, step length, gait speed, and observational gait were measured using the Foot Contact Scale (FCS) and the Physician's Rating Scale (PRS)...
June 2018: Brain & Development
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