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S Song, Y P Xu, Z F Wu, X J Deng, Q Wang
The combined and individual hydrological impacts of climate variation and urbanization have been extensively discussed over the past few decades, yet little is known about the relative impact of each. In this paper we took one of the most developed regions worldwide, Yangtze River Delta, as an example to analyse the long-term relative impacts of precipitation and urbanization change on water level alterations, based on precipitation, water level series, and annual impervious area data from 1960 to 2015. Abrupt changes detection in the water level series divided the data into the pre-impact period (1960-1988) and impacted period (1989-2015), and relative impacts of precipitation and urbanization on the water level increase from pre-impacted to impacted period, as well as their spatial and seasonal variations were estimated with the elasticity method...
August 2, 2018: Science of the Total Environment
Chunlin Li, Haowei Guo, Bangzheng Zong, Puming He, Fangyuan Fan, Shuying Gong
Special-grade green tea is a premium tea product with the best rank and high value. Special-grade green tea is normally classified by panel sensory evaluation which is time and sample costly. Near-infrared spectroscopy is considered as a promising rapid and non-destructive analytical technique for food quality evaluation and grading. This study established a discrimination method of special-grade flat green tea using Near-infrared spectroscopy. Full spectrum was used for partial least squares (PLS) modelling to predict the sensory scores of green tea, while specific spectral regions were used for synergy interval-partial least squares (siPLS) modelling...
August 1, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Preeti Prajapati, Jaya Pandey, Poonam Tandon, Kirti Sinha
Molecular structure, chemical and physical reactivity, spectroscopic behavior, intermolecular interactions play an important role in understanding the biological nature of pharmaceutical drugs. The objective of the study is to combine the spectroscopic and computational methodology for the investigation of structural behavior of ezetimibe (EZT). Computational study was done on monomeric, dimeric and trimeric models of EZT using B3LYP/6-311G(d,p). Hydrogen bond interactions were taken into consideration to validate the theoretical results with the experimental one...
August 13, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Natalie Martschuk, Jane Goodman-Delahunty, Martine B Powell, Nina J Westera
Little is known about the extent to whichinstitutional child sex offending differs from non-institutional offending. Strategies to secure the compliance of child victims were systematically compared to compare the modi operandi (prior to, during and following abuse), and the type of power (intimate, aggressive, coercive) applied by child sexual offenders in institutional versus non-institutional settings. A sample of 59 of the most recent child sexual abuse cases referred for prosecution in three Australian states was manually reviewed and coded...
August 15, 2018: Child Abuse & Neglect
Matthieu Hein, Jean-Pol Lanquart, Gwénolé Loas, Philippe Hubain, Paul Linkowski
Sleep plays an important role in cognitive functioning. However, few studies have investigated the sleep network organization. The aim of our study was to empirically investigate the presence and the stability with age of a small-world network organization during REM and slow-wave sleep using the effective connectivity measured by the Granger causality. Polysomnographic data from 30 healthy men recruited prospectively were analysed. To obtain the 19 × 19 connectivity matrix of all possible pairwise combinations of electrodes by the Granger causality method from our EEG data, we used the Toolbox MVGC multivariate Granger causality...
August 15, 2018: Neuroscience Research
L Quénéhervé, G David, A Bourreille, J B Hardouin, G Rahmi, N Neunlist, J Brégeon, E Coron
BACKGROUND AND AIMS: Confocal endomicroscopy (CLE) might discriminate mucosal lesions between Crohn's disease (CD) and ulcerative colitis (UC). However, the analysis of CLE images requires time-consuming methods, a long training time and potential impediments, such as significant interobserver variability. Therefore, we developed a computer-based method to analyze mucosal architecture from CLE images and discriminate between healthy subjects and patients with inflammatory bowel disease (IBD) as well as between UC and CD patients...
August 15, 2018: Gastrointestinal Endoscopy
Dengpeng Gao, Hongyue Zhang, Yafei Xu, Yun Liu, Huiying Xu, Jianguo Cui
Fluorescent copper nanoslusters (CuNCs) as a new class of fluorophores have attracted more and more attention due to their ease of synthesis, excellent optical properties, and low cost. In this study, a novel label-free fluorescent method was developed for the detection of DNA methyltransferases based on template length-dependent of dsDNA-CuNCs. In the absence of DNA adenine methylation methyltransferase (Dam MTase), the dsDNA containing the methylation-responsive sequence could effectively template the formation of fluorescent CuNCs with bright fluorescence...
August 15, 2018: Analytical Biochemistry
Fang Qiao, Na Li, Wei Li
BACKGROUND Lung cancer is the most lethal cancer worldwide. The aim of this study was to identify the tumor-related lncRNAs and explore their functions in female non-smokers with lung cancer. MATERIAL AND METHODS The gene expression microarray datasets GSE19804, GSE31210, and GSE31548 were downloaded from the Gene Expression Omnibus database. The differentially-expressed lncRNAs between non-smoking female lung cancer samples and non-tumor lung tissues were identified using GEO2R. RESULTS In total, 25, 40, and 15 differentially-expressed lncRNAs were obtained from GSE19804, GSE31210, and GSE31548 datasets (|logFC| >1, adj...
August 18, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Ichiro Tamaki, Koichiro Hata, Yusuke Okamura, Yermek Nigmet, Hirofumi Hirao, Toyonari Kubota, Osamu Inamoto, Jiro Kusakabe, Toru Goto, Tetsuya Tajima, Junichi Yoshikawa, Hirokazu Tanaka, Tatsuaki Tsuruyama, Rene H Tolba, Shinji Uemoto
Cold storage (CS) remains the gold standard for organ preservation worldwide, though it is inevitably associated with cold-ischemia/warm-reperfusion injury (IRI). Molecular hydrogen (H2 ) is well-known to have anti-oxidative properties, however, its unfavorable features, i.e. inflammability, low solubility, and high tissue/substance permeability, have hampered its clinical application. To overcome such obstacles, we developed a novel reconditioning method for donor organs, named HyFACS (hydrogen flush after cold storage), just an end-ischemic H2 -flush directly to donor organs ex vivo, and herein report its therapeutic impact against hepatic IRI...
August 18, 2018: Liver Transplantation
Rouven Nagel, Walter Durka, Oliver Bossdorf, Anna Bucharova
The growing number of restoration projects worldwide increases the demand for seed material of native species. To meet this demand, seeds are often produced through large-scale cultivation on specialized farms, using wild-collected seeds as the original sources. However, during cultivation plants experience novel environmental conditions compared to those in natural populations, and there is a danger that the plants in cultivation are subject to unintended selection and lose their adaptation to natural habitats...
August 18, 2018: Plant Biology
Allison C Waters, Ashan Veerakumar, Ki Sueng Choi, Bryan Howell, Vineet Tiruvadi, Kelly R Bijanki, Andrea Crowell, Patricio Riva-Posse, Helen S Mayberg
Deep brain stimulation (DBS) to the subcallosal cingulate cortex (SCC) is an emerging therapy for treatment resistant depression. Precision targeting of specific white matter fibers is now central to the model of SCC DBS treatment efficacy. A method to confirm SCC DBS target engagement is needed to reduce procedural variance across treatment providers and to optimize DBS parameters for individual patients. We examined the reliability of a novel cortical evoked response that is time-locked to a 2 Hz DBS pulse and shows the propagation of signal from the DBS target...
August 18, 2018: Human Brain Mapping
Elizabeth Vella, Shane McIver
ISSUE ADDRESSED: Identifying ways to manage the psychological and emotional costs of workplace stress is essential. Mindfulness meditation is reported to support mental wellbeing, however findings are limited in Australian business settings. Accordingly, this study explored the efficacy of a mindfulness meditation program tailored for an Australian public sector workplace. METHODS: A mixed-methods, single-group, pre/post-test design was used to evaluate a proof-of-concept mindfulness intervention...
August 18, 2018: Health Promotion Journal of Australia
Yoshinori Aragane, Hideaki Higashino
BACKGROUND: Far-infrared is well known with various therapeutic benefits. Recently, we have developed a novel far-infrared bathing system called the Enseki sandbath. In this regard, we focused on physical nature of ceramic to radiate far-infrared rays when heated adequately. METHODS: A bathtub was filled with ceramic beads and was equipped with computerized system which enabled to supply hot water over the ceramic beads and to drain out when beads were sufficiently heated...
August 18, 2018: Photodermatology, Photoimmunology & Photomedicine
Wioletta Mikuľáková, Eleonóra Klímová, Lucia Kendrová, Miloslav Gajdoš, Marek Chmelík
BACKGROUND The objective of this study was to evaluate the effect of a rehabilitation program in changing the perception of fatigue in patients with multiple sclerosis. MATERIAL AND METHODS The study involved 65 respondents/patients with clinically confirmed multiple sclerosis (54 women, 11 men, average age 46.49 years). The evaluation of the effects of fatigue on the physical, psychological, and psychosocial aspects of life was assessed using the Modified Fatigue Impact Scale (MFIS). To test the effectiveness of the neurorehabilitation program, we enrolled 2 groups: the experimental group (EG, n=32, 29 women, 3 men, Expanded Disability Status Scale (EDSS) 4...
August 18, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Wei Feng, Rui Shi, Chao Zhang, Shaojun Liu, Tingting Yu, Dan Zhu
To realize visualization of the skin microvascular dysfunction of type 1 diabetic mice, we combined laser speckle contrast imaging and hyperspectral imaging to simultaneously monitor the noradrenaline (NE)-induced responses of vascular blood flow and blood oxygen with the development of diabetes through optical clearing skin window. The main results showed that venous and arterious blood flow decreased without recovery after injection of NE; furthermore, the decrease of arterious blood oxygen induced by NE greatly weakened, especially for 2- and 4-week diabetic mice...
August 2018: Journal of Biomedical Optics
Benjamin W Fischer-Valuck, Brian C Baumann, Anthony Apicelli, Yuan James Rao, Michael Roach, Mackenzie Daly, Maria C Dans, Patrick White, Jessika Contreras, Lauren Henke, Hiram Gay, Jeff M Michalski, Christopher Abraham
Prostate cancer (PCa) is one of the most common malignancies associated with bone metastases, and palliative radiation therapy (RT) is an effective treatment option. A total of 2641 patients were identified with PCa and bone metastases at diagnosis from 2010 to 2014 in the NCDB. Fractionation scheme was designated as short course ([SC-RT]: 8 Gy in 1 fraction and 20 Gy in 5 fractions) vs long course ([LC-RT]: 30 Gy in 10 fractions and 37.5 Gy in 15 fractions). Patient characteristics were correlated with fractionation scheme using logistic regression...
August 17, 2018: Cancer Medicine
Yi He, Jingzhu Wang, Mengzhen Wang, Jingfang Zhang
Musk is the dried secretion of the musk pod (sac) of adult male musk deer, and has been used as perfume and traditional medicine for thousands of years. Steroid was regarded as one of the most important active compounds in musk. In order to protect the wild musk deer, musk deer farming has been carried out in China, India, and Nepal. However, it is hard to differentiate the two origins of musk by morphological identification. No other method has been reported so far for the discrimination of wild and domestic deer musk...
August 17, 2018: Journal of Mass Spectrometry: JMS
Gina L Marchini, Tina M Arredondo, Mitchell B Cruzan
The potential for rapid evolution in invasive species makes them useful for studying adaptive responses of populations to novel environments. However, phenotypic divergence during invasion is not necessarily due to selection, but may be a product of neutral processes resulting from population bottlenecks during colonization and range expansion. We investigated phenotypic adaptation during the establishment and range expansion of the invasive bunchgrass, slender false brome (Brachypodium sylvaticum; Poaceae)...
August 18, 2018: Journal of Evolutionary Biology
José Parada, Tamara Valenzuela, Francisca Gómez, Gonzalo Tereucán, Susana García, Pablo Cornejo, Peter Winterhalter, Antonieta Ruiz
BACKGROUND: Root colonization by arbuscular mycorrhizal (AM) fungi and adjusting the type of P supplementation by means of traditional (TF) or organic (OF) fertilization and the nutrient doses are among the main methods to increase the yield and especially the quality of strawberry fruit produced in acidic soils with low P availability. In this study, the antioxidant properties of strawberry fruit were evaluated under different treatments of fertilization (TF or OF) and different doses of P supplied at planting (0, 50 or 100% of the agronomic recommendation) and in the presence or absence of AM fungus as a bioinoculant...
August 17, 2018: Journal of the Science of Food and Agriculture
D Mangan, B V McCleary, H Culleton, C Cornaggia, R Ivory, V McKie, E Delaney, T Kargelis
BACKGROUND: In recent years there has been a surge in the number of commercially available lactose-free variants of a wide variety of products. This presents an analytical challenge for the measurement of the residual lactose content in the presence of high levels of mono-, di-, and oligosaccharides. RESULTS: In the current work, we describe the development of a novel enzymatic low-lactose determination method termed LOLAC which is based on an optimised glucose removal pre-treatment step followed by a sequential enzymatic assay which measures residual glucose and lactose in a single cuvette...
August 17, 2018: Journal of the Science of Food and Agriculture
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