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https://www.readbyqxmd.com/read/28213745/perceptions-of-parent-child-attachment-relationships-and-friendship-qualities-predictors-of-romantic-relationship-involvement-and-quality-in-adolescence
#1
Logan B Kochendorfer, Kathryn A Kerns
Relationships with parents and friends are important contexts for developing romantic relationship skills. Parents and friends may influence both the timing of involvement and the quality of romantic relationships. Three models of the joint influence of parents and friends (direct effects model, mediation model, and moderator model) have been proposed. The present study uses data from a longitudinal study (n = 1012; 49.8% female; 81.1% Caucasian) to examine how attachment and friendship quality at age 10 years predict romantic relationship involvement and quality at ages 12 and 15 years...
February 17, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28212080/improving-registration-robustness-for-image-guided-liver-surgery-in-a-novel-human-to-phantom-data-framework
#2
Jarrod Collins, Jared Weis, Jon Heiselman, Logan Clements, Amber Simpson, Willam Jarnagin, Michael Miga
In open image-guided liver surgery (IGLS), a sparse representation of the intraoperative organ surface can be acquired to drive image-to-physical registration. We hypothesize that uncharacterized error induced by variation in the collection patterns of organ surface data limits the accuracy and robustness of IGLS registration. Clinical validation of such registration methods is challenged due to the difficulty in obtaining data representative of the true state of organ deformation. We propose a novel human-to-phantom validation framework that transforms surface collection patterns from in vivo IGLS procedures (n=13) onto a well-characterized hepatic deformation phantom for the purpose of validating surface-driven, volumetric nonrigid registration methods...
February 13, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28212022/two-journals-sharing-one-name
#3
David L Sedlak, Bruce E Logan
No abstract text is available yet for this article.
February 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28210274/bilateral-tensor-fasciae-suralis-muscles-in-a-cadaver-with-unilateral-accessory-flexor-digitorum-longus-muscle
#4
Logan S W Bale, Sean O Herrin
Muscle variants are routinely encountered in the dissection laboratory and in clinical practice and therefore anatomists and clinicians need to be aware of their existence. Here we describe two different accessory muscles identified while performing educational dissection of a 51-year-old male cadaver. Tensor fasciae suralis, a rare muscle variant, was identified bilaterally and accessory flexor digitorum longus, a more common muscle variant, was present unilaterally. Tensor fasciae suralis and accessory flexor digitorum longus are clinically relevant muscle variants...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28198724/engaging-learners-to-advance-medical-education
#5
Jesse Burk-Rafel, R Logan Jones, Janice L Farlow
Learners are a pillar of academic medicine, yet their voice is seldom heard in national and international scholarly conversations on medical education. However, learners are eager to contribute: in response to a recent open call from Academic Medicine, medical students and residents representing 98 institutions across 11 countries submitted 224 Letters to the Editor on wide-ranging topics. In this Invited Commentary, the authors-three medical students serving in national leadership roles-contextualize several themes discussed in these learner-authored letters...
February 14, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28198300/a-passion-for-continence-care
#6
(no author information available yet)
Karen Logan trained at Cardiff University Hospital of Wales, qualifying in 1981. A nurse consultant since 2004, her current role is consultant nurse, continence care, and head of continence services at Aneurin Bevan University Health Board in Wales. She was named Nursing Standard Nurse of the Year in 2008, and last year was awarded a lifetime achievement award at the RCN Wales Nurse of the Year Awards 2016.
February 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28196457/dermal-absorption-of-fumigant-gases-during-hazmat-incident-exposure-scenarios-methyl-bromide-sulfuryl-fluoride-and-chloropicrin
#7
Sharyn Gaskin, Linda Heath, Dino Pisaniello, John W Edwards, Michael Logan, Christina Baxter
Accidental or intentional releases of toxic gases or vapors are the most common occurrence in hazardous material (HAZMAT) incidents that result in human injuries. The most serious hazard from exposure to gases or vapors is via the respiratory system. Dermal uptake, as a secondary route, is still a concern, most acutely for the unprotected public. There is a limited evidence base describing skin absorption of toxic gases and vapors in HAZMAT exposure scenarios, which are relatively brief compared with traditional test periods for skin absorption studies...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28195936/two-models-to-conduct-nonphysician-led-exercise-stress-testing-in-low-to-intermediate-risk-patients
#8
Adam Scott, Mark Whitman, Alice McDonald, Meghan Webster, Carly Jenkins
BACKGROUND: Exercise stress testing (EST) is a noninvasive procedure that aids the diagnosis and prognosis of a range of cardiac pathologies. Reduced access is recognized as a limiting factor in enabling early access to treatment or safe and appropriate discharge. Increased accessibility can be achieved by utilizing nonphysician health practitioners to supervise tests. To implement nonphysician-led EST in clinical environments, there is a need for the development and administration of feasible and effective models...
March 2017: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/28191891/mutations-in-donson-disrupt-replication-fork-stability-and-cause-microcephalic-dwarfism
#9
John J Reynolds, Louise S Bicknell, Paula Carroll, Martin R Higgs, Ranad Shaheen, Jennie E Murray, Dimitrios K Papadopoulos, Andrea Leitch, Olga Murina, Žygimantė Tarnauskaitė, Sarah R Wessel, Anastasia Zlatanou, Audrey Vernet, Alex von Kriegsheim, Rachel M A Mottram, Clare V Logan, Hannah Bye, Yun Li, Alexander Brean, Sateesh Maddirevula, Rachel C Challis, Kassiani Skouloudaki, Agaadir Almoisheer, Hessa S Alsaif, Ariella Amar, Natalie J Prescott, Michael B Bober, Angela Duker, Eissa Faqeih, Mohammed Zain Seidahmed, Saeed Al Tala, Abdulrahman Alswaid, Saleem Ahmed, Jumana Yousuf Al-Aama, Janine Altmüller, Mohammed Al Balwi, Angela F Brady, Luciana Chessa, Helen Cox, Rita Fischetto, Raoul Heller, Bertram D Henderson, Emma Hobson, Peter Nürnberg, E Ferda Percin, Angela Peron, Luigina Spaccini, Alan J Quigley, Seema Thakur, Carol A Wise, Grace Yoon, Maha Alnemer, Pavel Tomancak, Gökhan Yigit, A Malcolm R Taylor, Martin A M Reijns, Michael A Simpson, David Cortez, Fowzan S Alkuraya, Christopher G Mathew, Andrew P Jackson, Grant S Stewart
To ensure efficient genome duplication, cells have evolved numerous factors that promote unperturbed DNA replication and protect, repair and restart damaged forks. Here we identify downstream neighbor of SON (DONSON) as a novel fork protection factor and report biallelic DONSON mutations in 29 individuals with microcephalic dwarfism. We demonstrate that DONSON is a replisome component that stabilizes forks during genome replication. Loss of DONSON leads to severe replication-associated DNA damage arising from nucleolytic cleavage of stalled replication forks...
February 13, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28191371/the-effect-of-medical-student-volunteering-in-a-student-run-clinic-on-specialty-choice-for-residency
#10
Ashley Brown, Rahim Ismail, Glenn Gookin, Caridad Hernandez, Grace Logan, Magdalena Pasarica
INTRODUCTION:  Student-run free clinics (SRFCs) are a recent popular addition to medical school education, and a subset of studies has looked at the influence of SRFC volunteering on the medical student's career development. The majority of the research done in this area has focused on understanding if these SRFCs produce physicians who are more likely to practice medicine in underserved communities, caring for the uninsured. The remainder of the research has investigated if volunteering in an SRFC influences the specialty choice of medical school students...
January 9, 2017: Curēus
https://www.readbyqxmd.com/read/28190786/survival-in-portopulmonary-hypertension-outcomes-of-the-united-kingdom-national-pulmonary-arterial-hypertension-registry
#11
Sasiharan Sithamparanathan, Arun Nair, Logan Thirugnanasothy, J Gerry Coghlan, Robin Condliffe, Konstantinos Dimopoulos, Charlie A Elliot, Andrew J Fisher, Sean Gaine, J Simon R Gibbs, Michael A Gatzoulis, Clive E Handler, Luke S Howard, Martin Johnson, David G Kiely, James L Lordan, Andrew J Peacock, Joanna Pepke-Zaba, Benjamin E Schreiber, Karen K K Sheares, Stephen J Wort, Paul A Corris
BACKGROUND: Portopulmonary hypertension (PoPH) is a rare condition associated with poor survival, and the effect of modern therapies that target pulmonary arterial hypertension (PAH) on long-term outcome is unknown. This study investigated the baseline characteristics and survival in the cohort of patients diagnosed with PoPH in the United Kingdom National Pulmonary Hypertension Service. METHODS: A retrospective review was conducted of all incident treatment-naïve patients with PoPH within the United Kingdom national registry diagnosed between January 2001 and December 2010...
December 31, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28186407/x-ray-absorption-spectroscopy-reveals-an-organometallic-ni-c-bond-in-the-co-treated-form-of-acetyl-coa-synthase
#12
Mehmet Can, Logan J Giles, Stephen W Ragsdale, Ritimukta Sarangi
Acetyl CoA synthase (ACS) is a key enzyme in the Wood-Ljungdahl pathway of anaerobic CO2 fixation, which has long been proposed to operate by a novel mechanism involving a series of protein-bound organometallic (Ni-CO, methyl-Ni, acetyl-Ni) intermediates. Here we report the first direct structural evidence for the proposed metal-carbon bond. We describe the preparation of highly active metal-replete enzyme and near quantitative generation of the kinetically competent carbonylated intermediate. This advance has enabled a combination of Ni- and Fe-K-edge XAS and EXAFS experiments along with DFT calculations...
February 10, 2017: Biochemistry
https://www.readbyqxmd.com/read/28184247/a-versatile-2a-peptide-based-bicistronic-protein-expressing-platform-for-the-industrial-cellulase-producing-fungus-trichoderma-reesei
#13
Venkataramanan Subramanian, Logan A Schuster, Kyle T Moore, Larry E Taylor, John O Baker, Todd A Vander Wall, Jeffrey G Linger, Michael E Himmel, Stephen R Decker
BACKGROUND: The industrial workhorse fungus, Trichoderma reesei, is typically exploited for its ability to produce cellulase enzymes, whereas use of this fungus for over-expression of other proteins (homologous and heterologous) is still very limited. Identifying transformants expressing target protein is a tedious task due to low transformation efficiency, combined with highly variable expression levels between transformants. Routine methods for identification include PCR-based analysis, western blotting, or crude activity screening, all of which are time-consuming techniques...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28183460/corrigendum-to-metformin-suppresses-adipogenesis-through-both-amp-activated-protein-kinase-ampk-dependent-and-ampk-independent-mechanisms-mol-cell-endocrinol-440-15-january-2017-57-68
#14
S C Chen, R Brooks, J Houskeeper, S K Bremner, J Dunlop, B Viollet, P J Logan, I P Salt, S F Ahmed, S J Yarwood
No abstract text is available yet for this article.
March 5, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28180236/the-community-in-reach-rehabilitation-and-care-transition-ciract-clinical-and-cost-effectiveness-randomisation-controlled-trial-in-older-people-admitted-to-hospital-as-an-acute-medical-emergency
#15
Opinder Sahota, Ruth Pulikottil-Jacob, Fiona Marshall, Alan Montgomery, Wei Tan, Tracey Sach, Pip Logan, Denise Kendrick, Alison Watson, Maria Walker, Justin Waring
No abstract text is available yet for this article.
January 6, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28179570/architected-cellular-ceramics-with-tailored-stiffness-via-direct-foam-writing
#16
Joseph T Muth, Patrick G Dixon, Logan Woish, Lorna J Gibson, Jennifer A Lewis
Hierarchical cellular structures are ubiquitous in nature because of their low-density, high-specific properties, and multifunctionality. Inspired by these systems, we created lightweight ceramic architectures composed of closed-cell porous struts patterned in the form of hexagonal and triangular honeycombs by direct foam writing. The foam ink contains bubbles stabilized by attractive colloidal particles suspended in an aqueous solution. The printed and sintered ceramic foam honeycombs possess low relative density (∼6%)...
February 8, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28179391/the-nuclear-cap-binding-complex-mediates-meiotic-silencing-by-unpaired-dna
#17
Logan M Decker, Hua Xiao, Erin C Boone, Michael M Vierling, Benjamin S Shanker, Shanika L Kingston, Shannon F Boone, Jackson B Haynes, Patrick K T Shiu
In the filamentous fungus Neurospora crassa, cross walls between individual cells are normally incomplete, making the entire fungal network vulnerable to attack by viruses and selfish DNAs. Accordingly, several genome surveillance mechanisms are maintained to help the fungus to combat these repetitive elements. One of these defense mechanisms is known as meiotic silencing by unpaired DNA (MSUD), which is an RNA silencing system that identifies and silences unpaired genes during meiosis. Utilizing common RNAi proteins such as Dicer and Argonaute, MSUD targets mRNAs homologous to the unpaired sequence to achieve silencing...
February 7, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28178885/validation-of-an-automatic-reference-region-extraction-for-the-quantification-of-18-f-dpa-714-in-dynamic-brain-pet-studies
#18
Daniel García-Lorenzo, Sonia Lavisse, Claire Leroy, Catriona Wimberley, Benedetta Bodini, Philippe Remy, Mattia Veronese, Federico Turkheimer, Bruno Stankoff, Michel Bottlaender
There is a great need for a non-invasive methodology enabling the quantification of translocator protein overexpression in PET clinical imaging. [(18)F]DPA-714 has emerged as a promising translocator protein radiotracer as it is fluorinated, highly specific and returned reliable quantification using arterial input function. Cerebellum gray matter was proposed as reference region for simplified quantification; however, this method cannot be used when inflammation involves cerebellum. Here we adapted and validated a supervised clustering (supervised clustering algorithm (SCA)) for [(18)F]DPA-714 analysis...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28177741/modified-sprint-interval-training-protocols-part-ii-psychological-responses
#19
Logan K Townsend, Hashim Islam, Emily Dunn, Mark Eys, Jennifer Robertson-Wilson, Tom J Hazell
Sprint-interval training (SIT) is a viable method to improve health and fitness. However, researchers have questioned the utility of SIT due to its strenuous nature. The current study aimed to determine if manipulating the sprint and recovery duration, while maintaining the 1:8 work to rest ratio, could uncover a more favourable SIT protocol. Nine healthy active males (23.3±3.0 y, 22.4±2.2 kg·m<sup>-2</sup>, 48.9±5.3 mLkg<sup>-1</sup>min<sup>-1</sup>) participated in three experimental running SIT sessions: (1) 30:240 (4 x 30 sec efforts, 240 sec recovery); (2) 15:120 (8 x 15 sec efforts, 120 sec recovery); (3) 5:40 (24 x 5 sec efforts, 40 sec recovery); and (4) a final behavioural choice follow-up session...
December 7, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28177740/modified-sprint-interval-training-protocols-part-i-physiological-responses
#20
Hashim Islam, Logan K Townsend, Tom J Hazell
Adaptations to sprint interval training (SIT) are observed with brief (≤15s) work bouts highlighting peak power generation as an important metabolic stimulus. This study examined the effects of manipulating SIT work bout and recovery period duration on energy expenditure (EE) during and post-exercise, as well as post-exercise fat oxidation rates. Nine active males completed a resting control session (CTRL) and three SIT sessions in randomized order: 1) 30:240 (4 x 30 s bouts, 240 s recovery); 2) 15:120 (8 x 15 s bouts, 120 s recovery); 3) 5:40 (24 x 5 s bouts, 40 s recovery)...
December 8, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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