Read by QxMD icon Read


Maria Chuvochina, Christian Rinke, Donovan H Parks, Michael S Rappé, Gene W Tyson, Pelin Yilmaz, William B Whitman, Philip Hugenholtz
Naming of uncultured Bacteria and Archaea is often inconsistent with the International Code of Nomenclature of Prokaryotes. The recent practice of proposing names for higher taxa without designation of lower ranks and nomenclature types is one of the most important inconsistencies that needs to be addressed to avoid nomenclatural instability. The Code requires names of higher taxa up to the rank of class to be derived from the type genus name, with a proposal pending to formalise this requirement for the rank of phylum...
July 18, 2018: Systematic and Applied Microbiology
Dario Bertossi, Maurizio Cavallini, Pierfrancesco Cirillo, Salvatore Piero Fundarò, Sandro Quartucci, Chantal Sciuto, Davide Tonini, Gloria Trocchi, Massimo Signorini
BACKGROUND: The aesthetic treatment of facial and neck wrinkles with botulinum toxin is constantly increasing, thus making it necessary to collect procedures guidelines for the use of botulinum toxin in the treatment of wrinkles and/or cosmetic defects. METHODS: A group of nine Italian doctors, plastic and maxillo-facial surgeons, dermatologists and aesthetic physicians, experts in face and neck aesthetic treatments with onabotulinum toxin A, discussed on procedures used in their clinical practice...
August 9, 2018: Journal of Cosmetic Dermatology
Hafize Emine Sönmez, Pelin Esmeray, Ezgi Deniz Batu, Zehra Serap Arıcı, Selcan Demir, Erdal Sağ, Seza Özen, Yelda Bilginer
Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease in the world. The disease characteristics may vary in different age groups. In this study, we aimed to compare disease characteristics and treatment compliance according to the age of pediatric FMF patients. This is a single-center, cross-sectional study. Between August and October 2016, patients who were diagnosed with FMF, participated to the study. 378 pediatric FMF patients were enrolled in the study. Among those, age at symptom onset was ≤ 5 years in 69%, 6-11 years in 26% and ≥ 12 years in 5%...
August 7, 2018: Rheumatology International
Felizitas Bajerski, Johanna Stock, Benjamin Hanf, Tatyana Darienko, Elke Heine-Dobbernack, Maike Lorenz, Lisa Naujox, E R J Keller, H M Schumacher, Thomas Friedl, Sonja Eberth, Hans-Peter Mock, Olaf Kniemeyer, Jörg Overmann
In many natural environments, organisms get exposed to low temperature and/or to strong temperature shifts. Also, standard preservation protocols for live cells or tissues involve ultradeep freezing in or above liquid nitrogen (-196°C or -150°C, respectively). To which extent these conditions cause cold- or cryostress has rarely been investigated systematically. Using ATP content as an indicator of the physiological state of cells, we found that representatives of bacteria, fungi, algae, plant tissue, as well as plant and human cell lines exhibited similar responses during freezing and thawing...
2018: Frontiers in Physiology
Lijiao Gu, Hengling Wei, Hantao Wang, Junji Su, Shuxun Yu
BACKGROUND: WRKY transcription factors (TFs) participate in various physiological processes of plants. Although WRKY genes have been well studied in model plants, knowledge of the functional roles of these genes is still extremely limited in cotton. RESULTS: In this study, a group IId WRKY gene from cotton, GhWRKY42, was isolated and characterized. Our data showed that GhWRKY42 localized to the nucleus. A transactivation assay in yeast demonstrated that GhWRKY42 was not a transcriptional activator...
July 30, 2018: BMC Genetics
Rute J Macedo-de-Araújo, Ana Amorim-de-Sousa, António Queirós, Eef van der Worp, José M González-Méijome
PURPOSE: To analyze the relationship between corneal sagittal height and asymmetry parameters derived from Placido-videokeratoscopy with the parameters of fitted scleral lenses (ScCLs). METHODS: Corneal topographies were measured with MedmontE300 in a total of 126 eyes with irregular and regular corneas before ScCL fitting were analyzed. Measurements of sagittal height (OC-SAG) at steep and flat corneal meridians were obtained for 10 mm and 12 mm chords. Estimated Height (EHChord) parameters were taken for a chord equal to the diameter of the lens that each subject was wearing at different semi-meridians...
July 25, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Xiaomeng Wang, Xuesong Wang
Road alignments that combine horizontal and vertical curves on freeways have effects on drivers' speed changes that can lead to safety problems. This study examines speed changes on four types of combined curves: downslope, upslope, crest and sag. From design blueprints for a mountainous freeway under construction in Hunan Province, a total of 70 combined curves were programmed into the Tongji University driving simulator. Study participants drove through the simulated freeway while vehicle operation data was continuously captured...
July 24, 2018: Accident; Analysis and Prevention
Christian Rothermundt, Claudio Thurneysen, Richard Cathomas, Beat Müller, Walter Mingrone, Anita Hirschi-Blickenstorfer, Tobias Wehrhahn, Christian Ruf, Sacha Rothschild, Bettina Seifert, Angelika Terbuch, Thomas Grassmugg, Regina Woelky, Christian Fankhauser, Thomas Kunit, Natalie Fischer Fischer, Roman Inauen, Jörn Kamradt, Katrin Ziegler, Alan Haynes, Peter Jüni, Silke Gillessen
BACKGROUND: The majority of germ cell tumour (GCT) patients can be cured by orchiectomy followed by active surveillance or subsequent systemic and/or local treatments. There are various guidelines for a structured follow-up including radiographic and clinical examinations. OBJECTIVE: The Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS) prospectively evaluates follow-up, indicator of relapse and late toxicities. This is a descriptive analysis; we present baseline characteristics and treatment strategies for the first 299 patients with primary GCT or relapsed GCT after completion of treatment...
2018: Swiss Medical Weekly
Vimal Kumar Semwal, Renu Khanna-Chopra
Reproductive sinks regulate monocarpic senescence in wheat as desinking delayed flag leaf senescence under irrigated condition. In this study, wheat cv. HW 2041 and its isonuclear male sterile line (CMS) were subjected to post-anthesis water deficit stress to understand the association between sink strength, senescence and drought response in relation to oxidative stress and antioxidant defense at cellular and sub-cellular level. CMS plants maintained better water relations and exhibited delayed onset and progression of flag leaf senescence in terms of green leaf area, chlorophyll and protein content than fertile plants under water deficit stress (WDS)...
July 2018: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
Bin Song, Weiquan Tan, Yue Xu, Taihui Yu, Weiping Li, Zhong Chen, Rui Yang, Jingyi Hou, Yunfeng Zhou
PURPOSE: This study compared the diagnostic accuracy of second-look arthroscopy, clinical assessment, and magnetic resonance imaging (MRI) in evaluating meniscal healing following repair. To explore the application of 3D-MRI sequences with signal-to-noise ratio (SNR) measurements and the analysis of sensitivity and accuracy in evaluating meniscal healing status after meniscal repair. METHODS: This study included 75 patients (75 menisci; mean age, 25.4 ± 6.6 years) who underwent arthroscopic meniscal repair (medial menisci, 45; and lateral menisci, 29)...
July 23, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Mark F Reinking, Leigh Dugan, Nolan Ripple, Karen Schleper, Henry Scholz, Jesse Spadino, Cameron Stahl, Thomas G McPoil
Background: While two-dimensional (2D) video running analysis is commonly performed in the clinical setting, the reliability of quantitative measurements as well as effect of clinical experience has not been studied. Purpose: The purpose of this study was to assess the intra-rater and inter-rater reliability of six different raters using 2D video analysis of sagittal and frontal plane kinematic variables while running on a treadmill. Study Design: Cross-sectional Study...
June 2018: International Journal of Sports Physical Therapy
Zhe Li, Jun Chen, Jianbo Cheng, Sicong Huang, Yingyu Hu, Yijuan Wu, Guihua Li, Bo Liu, Xian Liu, Wenyuan Guo, Shuxuan Huang, Miaomiao Zhou, Xiang Chen, Yousheng Xiao, Chaojun Chen, Junbin Chen, Xiaodong Luo, Pingyi Xu
Objective: To investigate the effect of acupuncture on Parkinson's disease (PD) patients with tremor and its potential neuromechanism by functional magnetic resonance imaging (fMRI). Methods: Forty-one PD patients with tremor were randomly assigned to true acupuncture group (TAG, n = 14), sham acupuncture group (SAG, n = 14) and waiting group (WG, n = 13). All patients received levodopa for 12 weeks. Patients in TAG were acupunctured on DU20, GB20, and the Chorea-Tremor Controlled Zone, and patients in SAG accepted sham acupuncture, while patients in WG received no acupuncture treatment until 12 weeks after the course was ended...
2018: Frontiers in Aging Neuroscience
Zhi Yang, Jun Yao, Xin Cao
The inner ear is a complex sensory organ that detects sound and mediates balance. During inner ear development, fibroblast growth factor (FGF) signaling pathway is involved in the induction of otic placode, cell fate determination of statoacoustic ganglion (SAG) neurons, and epithelial differentiation of the Corti organ. FGF signaling initiates the regulatory network of otic genes in the early development of inner ear, and induces the formation of pre-placodal region and the otic placode. The specification of the neuroblast ventral to the otic vesicle could be promoted by the normally-expressed FGF, and inhibited by excessive FGF5 secreted by mature SAG neurons, which could form a negative feedback loop and stabilize the SAG cell identity...
July 20, 2018: Yi Chuan, Hereditas
Tim G A Calon, Martin L Johansson, Arthur J G de Bruijn, Herbert van den Berge, Mariet Wagenaar, Edwin Eichhorn, Miranda M L Janssen, Janny R Hof, Jan-Wouter Brunings, Manuela A Joore, Sofia Jonhede, Joost van Tongeren, Marcus Holmberg, Robert-Jan Stokroos
OBJECTIVE: To compare the surgical outcomes of the Minimally Invasive Ponto Surgery (MIPS) technique with those of the linear incision technique with soft-tissue preservation for bone-anchored hearing systems (BAHS). DESIGN: Sponsor-initiated multicenter, open, randomized, controlled clinical trial. SETTING: Maastricht University Medical Centre, Ziekenhuisgroep Twente and Medisch Centrum Leeuwarden, all situated in The Netherlands. PARTICIPANTS: Sixty-four adult patients eligible for unilateral BAHS surgery...
August 2018: Otology & Neurotology
Qishuo Wang, Xuepeng Wang, Xuemei Wang, Ruijuan Feng, Qian Luo, Jinjing Huang
Streptococcus agalactiae (S. agalactiae) is a gram-positive pathogen that causes a wide range of infections in fish and other animals including humans. Bacterial ghosts (BGs) are nonliving, empty cell envelopes and are well represented as novel vaccine candidates. In this study, we examined the immunogenicity and protective efficacy of S. agalactiae ghosts (SAG) against a virulent challenge in tilapia. Nonliving SAG was generated by a culture with Penicillin and Streptolysin, and then treated with the MIC of sodium hydroxide...
June 30, 2018: Fish & Shellfish Immunology
David G Quirk, Lars H Rüpke
The division of the earth's surface into continents and oceans is a consequence of plate tectonics but a geological paradox exists at continent-ocean boundaries. Continental plate is thicker and lighter than oceanic plate, floating higher on the mantle asthenosphere, but it can rift apart by thinning and heating to form new oceans. In theory, continental plate subsides in proportion to the amount it is thinned and subsequently by the rate it cools down. However, seismic and borehole data from continental margins like the Atlantic show that the upper surface of many plates remains close to sea-level during rifting, inconsistent with its thickness, and subsides after breakup more rapidly than cooling predicts...
July 3, 2018: Scientific Reports
Deepa Sritharan, Parinaz Fathi, Jason D Weaver, Stephen M Retta, Changfu Wu, Nandini Duraiswamy
After implantation of a transcatheter bioprosthetic heart valve its original circular circumference may become distorted, which can lead to changes in leaflet coaptation and leaflets that are stretched or sagging. This may lead to early structural deterioration of the valve as seen in some explanted transcatheter heart valves. Our in vitro study evaluates the effect of leaflet deformations seen in elliptical configurations on the damage patterns of the leaflets, with circular valve deformation as the control...
June 12, 2018: Cardiovascular Engineering and Technology
Ming-Lun Chou, Wan-Yu Liao, Wan-Chen Wei, Althea Yi-Shan Li, Ching-Ying Chu, Chia-Ling Wu, Chun-Lin Liu, Ting-Han Fu, Lee-Fong Lin
The chloroplast relies on proteins encoded in the nucleus, synthesized in the cytosol and subsequently transported into chloroplast through the protein complexes Toc and Tic (Translocon at the outer/inner membrane of chloroplasts). A Tic complex member, Tic55, contains a redox-related motif essential for protein import into chloroplasts in peas. However, Tic55 is not crucial for protein import in Arabidopsis . Here, a tic55-II -knockout mutant of Arabidopsis thaliana was characterized for Tic55 localization, its relationship with other translocon proteins, and its association with plant leaf senescence when compared to the wild type...
June 23, 2018: International Journal of Molecular Sciences
Dorothy A Thompson, Kaoru Fujinami, Ido Perlman, Ruth Hamilton, Anthony G Robson
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum procedure, but encourages more extensive testing. This ISCEV extended protocol describes an extension to the ERG standard, namely the dark-adapted (DA) red flash ERG. The DA red flash ERG can be incorporated conveniently within the ISCEV standard ERG protocol after a minimum of 20-min DA and recorded after the DA 0.01 ERG to a flash strength of 0.3 phot cd s m-2 , eliciting a waveform with two positive peaks in healthy individuals...
June 22, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
Daiki Kakiuchi, Kenichiro Saito, Takeshi Mitsui, Yoshinori Munemoto, Yoshihiro Takashima, Susumu Amaya, Masanari Shimada, Yosuke Kato
A 75-year-old woman underwent laparoscopic abdominoperineal resection. Four months after abdominoperineal resection, the patient complained of a perineal bulge and urination disorder. Abdominal CT showed protrusion of the small intestine and bladder to the perineum. The patient underwent laparoscopic hernia repair with mesh. The size of the hernial orifice was 7.0 × 9.0 cm, and it had no solid rim. The mesh was tacked ventrally to the pectineal ligament and dorsally to the sacrum, and then sutured on the lateral side...
June 19, 2018: Asian Journal of Endoscopic Surgery
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"