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https://www.readbyqxmd.com/read/30325887/design-and-implementation-of-an-enhanced-recovery-after-surgery-eras-program-for-minimally-invasive-lumbar-decompression-spine-surgery-initial-experience
#1
Ellen M Soffin, Avani S Vaishnav, Douglas Wetmore, Lauren Barber, Patrick Hill, Catherine Himo Gang, James D Beckman, Todd J Albert, Sheeraz A Qureshi
STUDY DESIGN: A retrospective cohort study of prospectively-collected data. OBJECTIVE: To describe the development of and early experience with an evidence-based ERAS pathway for lumbar decompression. SUMMARY OF BACKGROUND DATA: Enhanced recovery after surgery (ERAS) protocols have been consistently associated with improved patient experience and outcomes, and reduced cost and length of hospital stay (LoS). Despite successes in other orthopedic subspecialties, ERAS has yet to be established in spine surgery...
October 15, 2018: Spine
https://www.readbyqxmd.com/read/30325260/empathy-in-vaccination-counselling-a-survey-on-the-impact-of-a-three-day-residential-course
#2
Massimo Maurici, Michele Arigliani, Valentina Dugo, Carlo Leo, Valentina Pettinicchio, Raffaele Arigliani, Elisabetta Franco
BACKGROUND: In an era of hesitance to use vaccines, the importance of effective communication for increasing vaccine acceptance is well known. This study aimed to assess the impact of a three-day residential course concerning empathy and counselling abilities on patients' ratings of the level of empathy of physicians and nurses working in vaccination centers. METHODS: The empathy of healthcare providers was evaluated using the Adapted Consultation and Relational Empathy (CARE) Measure...
October 16, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/30307524/impact-of-pharmacy-initiated-interventions-on-influenza-vaccination-rates-in-pediatric-solid-organ-transplant-recipients
#3
Sara Gattis, Inci Yildirim, Andi L Shane, Staci Serluco, Courtney McCracken, Rochelle Liverman
Background: In solid organ transplant (SOT) recipients, influenza infection can lead to subsequent graft dysfunction and death. Vaccination is the most effective approach to preventing influenza infection; however, vaccination rates are low, and interventions to optimize vaccine coverage are needed. The purpose of this study was to evaluate if pharmacy-initiated screening and recommendations for influenza immunization improve the rate of vaccination in pediatric SOT recipients. Methods: We performed a retrospective pre-post chart review of all kidney, liver, and heart transplant recipients followed by Children's Healthcare of Atlanta/Emory University transplant services between September 1, 2011, and February 16, 2017...
October 11, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/30303674/a-physiologist-observing-and-reporting-supra-pharmacologic-dobutamine-stress-testing-can-we-trust-them-and-can-we-trust-the-results
#4
EDITORIAL
Thomas R Porter
In a study, published in this issue of Echo Research and Practice, Ntoskas et al. retrospectively analyzed the safety of a cardiac physiologist performing, and interpreting, Dobutamine stress echocardiography (DSE) in of 300 patients undergoing DSE for the detection of inducible reversible ischemia, myocardial viability and valvular heart disease. While safety during the tests themselves did not appear to be compromised with this unsupervised approach, the interpretation of these DSEs causes concerns regarding broad patient safety relative to misread results...
September 1, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/30303179/laparoscopic-surgery-within-an-enhanced-recovery-after-surgery-eras-protocol-reduced-postoperative-ileus-by-increasing-postoperative-treg-levels-in-patients-with-right-side-colon-carcinoma
#5
Honggang Wang, Yong Wang, Hailin Xing, Yaxing Zhou, Jie Zhao, Jianguo Jiang, Qinghong Liu
BACKGROUND The aim of this study was to determine the effects of laparoscopic surgery within an ERAS program on outcomes and immunological function in patients with a carcinoma in the right colon. MATERIAL AND METHODS Patient data were acquired from a prospectively maintained database, and 176 patients diagnosed with right colon carcinoma with surgery were selected from the database. These patients were divided into a laparoscopic group (Lap group, n=86) and an open operation group (Open group, n=90). All patients received treatment according to a standardized ERAS protocol...
October 10, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/30302644/aso-author-reflections-multimodal-enhanced-recovery-after-surgery-eras-program-in-totally-laparoscopic-distal-gastrectomy-for-gastric-cancer-what-have-we-learned
#6
So Hyun Kang, Young Suk Park, Do Joong Park, Hyung-Ho Kim, Sang-Hoon Ahn
No abstract text is available yet for this article.
October 9, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/30301641/impact-of-rotavirus-vaccine-introduction-and-genotypic-characteristics-of-rotavirus-strains-in-children-less-than-5-years-of-age-with-gastroenteritis-in-ethiopia-2011-2016
#7
Almaz Abebe, Mekonen Getahun, Seheri L Mapaseka, Berhane Beyene, Essete Assefa, Birke Teshome, Mesfin Tefera, Ferehiwot Kebede, Abebe Habtamu, Tewodros Haile-Mariam, M Jeffrey Mphahlele, Fasil Teshager, Ayesheshem Ademe, Telahun Teka, Goitom G Weldegebriel, Jason M Mwenda
INTRODUCTION: A monovalent rotavirus vaccine was introduced in the Ethiopian Expanded Program on Immunization from November 2013. We compared impact of rotavirus vaccine introduction on rotavirus associated acute diarrhea hospitalizations and genotypic characteristics of rotavirus strains pre-and post-vaccine introduction. METHODS: Sentinel surveillance for diarrhea among children <5 years of age was conducted at 3 hospitals in Addis Ababa, Ethiopia from 2011 to 2017...
October 6, 2018: Vaccine
https://www.readbyqxmd.com/read/30300660/robot-assisted-partial-nephrectomy-is-routine-urinary-catheterization-still-mandatory-in-the-era-of-enhanced-recovery
#8
Benjamin Tremblais, Inès Dominique, Jean-Etienne Terrier, René Ecochard, Hélène Hacquard, Alain Ruffion, Philippe Paparel
OBJECTIVE: To assess the benefits and safety of non-catheterization during robot-assisted partial nephrectomy within an enhanced recovery protocol. MATERIALS AND METHODS: A single-center retrospective comparative study was carried out of consecutive patients who underwent a robot-assisted partial nephrectomy between February 2015 and December 2017 within an early recovery program. The patients who received a urinary catheter were compared with those who did not in terms of postoperative complications, acute urinary retention rates, urinary tract infection rates, and lengths of hospital stay...
October 6, 2018: Urology
https://www.readbyqxmd.com/read/30294954/new-clinical-trial-designs-for-establishing-drug-efficacy-and-safety-in-a-precision-medicine-era
#9
REVIEW
Hiddo J L Heerspink, James List, Vlado Perkovic
Despite advances in pharmacotherapy, diabetic kidney disease (DKD) remains associated with a high burden of micro- and macrovascular complications often leading to premature mortality. New therapies are highly desirable to mitigate the burden of this disease. However, there are a number of barriers that hamper drug development in DKD. These include, amongst others, the lengthy and complex clinical trials required to prove drug efficacy and safety, inefficiencies in clinical trial conduct, and the high costs associated with these development programs...
October 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/30288693/early-ileostomy-reversal-after-minimally-invasive-surgery-and-eras-program-for-mid-and-low-rectal-cancer
#10
Corrado Pedrazzani, Federica Secci, Eduardo Fernandes, Ivans Jelovskijs, Giulia Turri, Cristian Conti, Andrea Ruzzenente, Alfredo Guglielmi
Diverting loop ileostomy following low anterior resection (LAR) is known to decrease quality of life and prolongs the return back to patients' baseline activity. The aim of this retrospective study was to explore feasibility and safety of an early ileostomy reversal strategy in a cohort of patients undergoing minimally invasive LAR within an enhanced recovery after surgery (ERAS) program. Prospectively collected data from 15 patients who underwent minimally invasive LAR and diverting ileostomy at the Division of General and Hepatobiliary Surgery, University of Verona Hospital Trust between September 2015 and December 2016 were retrospectively analyzed...
October 4, 2018: Updates in Surgery
https://www.readbyqxmd.com/read/30286735/the-landscape-of-vaccines-in-china-history-classification-supply-and-price
#11
Yaming Zheng, Lance Rodewald, Juan Yang, Ying Qin, Mingfan Pang, Luzhao Feng, Hongjie Yu
BACKGROUND: Vaccine regulation in China meets World Health Organization standards, but China's vaccine industry and immunization program have some characteristics that differ from other countries. We described the history, classification, supply and prices of vaccines available and used in China, compared with high-and middle-incomes countries to illustrate the development of Chinese vaccine industry and immunization program. METHODS: Immunization policy documents were obtained from the State Council and the National Health and Family Planning Commission (NHFPC)...
October 4, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/30286030/enhanced-recovery-after-cardiac-surgery-program-to-improve-patient-outcomes
#12
Gina McConnell, Patricia Woltz, William T Bradford, J Erin Ledford, Judson B Williams
This article details the obstacles of implementing a cardiac-specific enhanced recovery after surgery (ERAS) program in a 919-bed not-for-profit community-based health system and the benefits of ERAS programs for different patient populations.
October 3, 2018: Nursing
https://www.readbyqxmd.com/read/30283874/racism-african-american-women-and-their-sexual-and-reproductive-health-a-review-of-historical-and-contemporary-evidence-and-implications-for-health-equity
#13
REVIEW
Cynthia Prather, Taleria R Fuller, William L Jeffries, Khiya J Marshall, A Vyann Howell, Angela Belyue-Umole, Winifred King
Background: The sexual and reproductive health of African American women has been compromised due to multiple experiences of racism, including discriminatory healthcare practices from slavery through the post-Civil Rights era. However, studies rarely consider how the historical underpinnings of racism negatively influence the present-day health outcomes of African American women. Although some improvements to ensure equitable healthcare have been made, these historical influences provide an unexplored context for illuminating present-day epidemiology of sexual and reproductive health disparities among African American women...
2018: Health Equity
https://www.readbyqxmd.com/read/30283493/genome-wide-and-trait-specific-markers-a-perspective-in-designing-conservation-programs
#14
Hao Sun, Babatunde Shittu Olasege, Zhong Xu, Qingbo Zhao, Peipei Ma, Qishan Wang, Shaoxiong Lu, Yuchun Pan
Nowadays, breed conservation has entered the genomics era and it is imperative to develop novel theory to design the breeding schemes of the conservation populations by using the genomic information. The genome-wide markers have been regarded as a useful strategy to maintain genetic diversity. However, using the genome-wide SNPs to optimize diversity might not be optimal for some specific loci associated with specific-traits. Using the sequencing data of the conserved population of the Saba pig breed, we demonstrated that the conservation program designed by using the genome-wide SNPs might result in the loss of the genetic diversity of the reproduction trait...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/30277835/optimizing-cancer-immunotherapy-is-it-time-for-personalized-predictive-biomarkers
#15
Milena Music, Ioannis Prassas, Eleftherios P Diamandis
Cancer immunotherapy, a treatment that selectively augments a patient's anti-tumor immune response, is a breakthrough advancement in personalized medicine. A subset of cancer patients undergoing immunotherapy have displayed robust and long-lasting therapeutic responses. Currently, the spotlight is on the use of blocking antibodies against the T-cell checkpoint molecules, cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programed cell death-1 (PD-1)/programed death-ligand 1 (PD-L1), which have been effectively used to combat many cancers types...
October 2, 2018: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/30276441/guidelines-for-perioperative-care-in-esophagectomy-enhanced-recovery-after-surgery-eras-%C3%A2-society-recommendations
#16
REVIEW
Donald E Low, William Allum, Giovanni De Manzoni, Lorenzo Ferri, Arul Immanuel, MadhanKumar Kuppusamy, Simon Law, Mats Lindblad, Nick Maynard, Joseph Neal, C S Pramesh, Mike Scott, B Mark Smithers, Valérie Addor, Olle Ljungqvist
INTRODUCTION: Enhanced recovery after surgery (ERAS) programs provide a format for multidisciplinary care and has been shown to predictably improve short term outcomes associated with surgical procedures. Esophagectomy has historically been associated with significant levels of morbidity and mortality and as a result routine application and audit of ERAS guidelines specifically designed for esophageal resection has significant potential to improve outcomes associated with this complex procedure...
October 1, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/30276363/progress-in-targeted-therapy-for-breast-cancer
#17
Jie Ju, An-Jie Zhu, Peng Yuan
Breast cancer is a multistep, multifactorial, and heterogeneous disease. Significant transformations have occurred in the systemic management of breast cancer in the past decade. Due to the further understanding of pathogenesis, scientists have found plenty of signaling pathways and correspondingly therapeutic targets in breast cancer, such as hormone receptor, human epidermal growth factor receptor 2 (HER2), epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF), phosphoinositide-3-kinase (PI3K), v-akt murine thymoma viral oncogene homolog (AKT), mechanistic target of rapamycin (mTOR), cyclin-dependent kinase 4/6 (CDK4/6), poly (adenosine diphosphate-ribose) polymerase (PARP), and programmed death-1 (PD-1)...
September 2018: Chronic Diseases and Translational Medicine
https://www.readbyqxmd.com/read/30276000/enhanced-recovery-after-surgery-for-gastric-cancer-patients-improves-clinical-outcomes-at-a-us-cancer-center
#18
Jacopo Desiderio, Camille L Stewart, Virginia Sun, Laleh Melstrom, Susanne Warner, Byrne Lee, Hans F Schoellhammer, Vijay Trisal, Benjamin Paz, Yuman Fong, Yanghee Woo
Purpose: Enhanced recovery after surgery (ERAS) protocols for gastric cancer patients have shown improved outcomes in Asia. However, data on gastric cancer ERAS (GC-ERAS) programs in the United States are sparse. The purpose of this study was to compare perioperative outcomes before and after implementation of an GC-ERAS protocol at a National Comprehensive Cancer Center in the United States. Materials and Methods: We reviewed medical records of patients surgically treated for gastric cancer with curative intent from January 2012 to October 2016 and compared the GC-ERAS group (November 1, 2015-October 1, 2016) with the historical control (HC) group (January 1, 2012-October 31, 2015)...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30272202/a-multi-site-study-of-social-cognitive-factors-related-to-adherence-among-youth-living-with-hiv-in-the-new-era-of-antiretroviral-medication
#19
Veronica Dinaj-Koci, Bo Wang, Sylvie Naar-King, Karen Kolmodin MacDonell
Objective: The goal of the current study was to determine how a set of social cognitive factors predict antiretroviral therapy (ART) medication adherence in youth living with HIV in an era of newer highly active ART medications using a conceptual model. Methods: Behaviorally infected youth living with HIV ages 13-24 (N = 822) from 14 sites within the Adolescent Medicine Trials Unit (AMTU) were included in the study. Structural equation modeling was used to explore predictors of ART medication adherence...
September 28, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/30271306/report-from-the-medical-library-association-s-insight-initiative-summit-1-engaging-users-in-a-disruptive-era
#20
Katherine G Akers
At the Medical Library Association's Insight Initiative Summit 1, held March 6-7, 2018, academic and hospital librarians and publishing industry partners came together to discuss their shared role in engaging users of health sciences information in an era in which "disruptors" such as pirate websites, scientific collaboration networks, and preprint servers pose threats to traditional means of access to scholarly content. Through a mixture of keynote talks, themed panel discussions, and small-group problem-solving exercises, the summit program raised important questions, sparked conversation, and provided insight into the need for both libraries and publishing organizations to improve their user experience, lower their barriers to access, and offer value to users that cannot be provided by competitors, including helping authors and students become informed, responsible advocates for and consumers of scholarly publications...
October 2018: Journal of the Medical Library Association: JMLA
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