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https://www.readbyqxmd.com/read/30507882/anatomic-landmarks-in-transoral-oropharyngeal-surgery
#1
Rosa M Mirapeix, Marc Tobed Secall, Carlos Pollán Guisasola, Jacinto Garcia Lorenzo, Jordi Lluansí Planella, Constanza Viña Soria, Mar Palau Viarnès, David Virós Porcuna
INTRODUCTION: Minimally invasive transoral surgery for oropharyngeal cancer is a challenge for head and neck surgeons because of the inside-out anatomic presentation and the confined workspace. This study was performed to describe the main neurovascular and muscular landmarks in a transoral approach. The authors propose an anatomic stratification for this surgery. MATERIALS AND METHODS: Lateral wall of the oropharynx and base of the tongue of 15 formalin-fixed heads (30 sides) and 5 fresh cadaveric heads (10 sides) sagittal sectioned were dissected from the inside outwards...
November 30, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/30496905/intentional-targeted-false-lumen-occlusion-after-aortic-dissection-a-systematic-review-of-the-literature
#2
REVIEW
Konstantinos Spanos, Tilo Kölbel, Fiona Rohlffs, Franziska Heidemann, Athanasios D Giannoukas, Sebastian E Debus, Nikolaos Tsilimparis
BACKGROUND: Residual patent false lumen (FL) after chronic type B (cTBAD) or type A aortic dissection (TAAD) treatment is independently associated with poor long-term outcome. The aim of our study was to present endovascular techniques and the existing experience of targeted false lumen (FL) thrombosis after cTBAD or type A TAAD treatment. MATERIAL AND METHODS: A systematic review was performed (PRISMA) searching in MEDLINE, CENTRAL, and Cochrane databases including studies reporting on targeted FL occlusion after cTBAD or TAAD...
November 26, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30478394/establishing-a-prediction-model-for-lateral-neck-lymph-node-metastasis-in-patients-with-papillary-thyroid-carcinoma
#3
Shan Jin, Wuyuntu Bao, Yun-Tian Yang, Tala Bai, Yinbao Bai
This study aimed to establish a model for predicting lateral neck lymph node metastasis in patients with papillary thyroid carcinoma. A total of 106 patients with papillary thyroid carcinoma undergoing initial treatment of neck lymph node dissection (including central and lateral neck lymph nodes) at the thyroid surgery department were enrolled from January 2009 to April 2017. Logistic regression analysis was used to screen the factors influencing lateral neck lymph node metastasis and develop a prediction model...
November 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30476965/association-of-hospital-volume-with-laryngectomy-outcomes-in-patients-with-larynx-cancer
#4
Christine G Gourin, C Matthew Stewart, Kevin D Frick, Carole Fakhry, Karen T Pitman, David W Eisele, J Matthew Austin
Importance: A volume-outcome association exists for larynx cancer surgery, but to date it has not been investigated for specific surgical procedures. Objectives: To characterize the volume-outcome association specifically for laryngectomy surgery and to identify a minimum hospital volume threshold associated with improved outcomes. Design, Setting, and Participants: In this cross-sectional study, the Nationwide Inpatient Sample was used to identify 45 156 patients who underwent laryngectomy procedures for a malignant laryngeal or hypopharyngeal neoplasm between January 2001 and December 2011...
November 21, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/30465086/occult-contralateral-lateral-lymph-node-metastases-in-unilateral-n1b-papillary-thyroid-carcinoma
#5
Hélène Bohec, Ingrid Breuskin, Julien Hadoux, Martin Schlumberger, Sophie Leboulleux, Dana M Hartl
OBJECTIVE: Therapeutic lateral neck dissection (ND) is recommended for N1b papillary thyroid carcinoma (PTC), while prophylactic contralateral lateral ND is not. Given the paucity of data, we investigated the frequency of and risk factors for occult lymph node metastases (LNM) in the contralateral lateral neck for N1b patients. PATIENTS AND METHODS: This is a retrospective study conducted at a cancer center. Inclusion criteria were: unilateral PTC and ipsilateral lateral LNM confirmed by fine-needle aspiration biopsy...
November 21, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/30455668/intrathyroidal-parathyroid-carcinoma-an-atypical-thyroid-lesion
#6
Noran Alharbi, Sylvia L Asa, Marta Szybowska, Raymond H Kim, Shereen Ezzat
Parathyroid carcinoma is a rare endocrine malignancy that is typically difficult to diagnose at presentation. Here, we report a 63 year-old man who had symptomatic hypercalcemia. Investigations revealed a thyroid nodule and a lateral neck mass that was biopsied and diagnosed as "suspicious for a neuroendocrine neoplasm." He underwent total thyroidectomy with central and left neck node dissection. Histology and immunohistochemistry revealed an intrathyroidal angioinvasive parathyroid carcinoma with lymph node metastases...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/30429678/calcium-stimulated-calcitonin-the-new-standard-in-the-diagnosis-of-thyroid-c-cell-disease-clinically-relevant-gender-specific-cut-off-levels-for-an-old-test
#7
Martin B Niederle, Christian Scheuba, Alois Gessl, Shuren Li, Oskar Koperek, Christian Bieglmayer, Philipp Riss, Andreas Selberherr, Bruno Niederle
Introduction: Pentagastrin (Pg) stimulated calcitonin (sCT) was used to enhance accuracy in medullary thyroid cancer (MTC) diagnosis. As it is now unavailable, calcium (Ca) has been recommended as an alternative. The aim of this study was to define gender-specific cut-off values to predict MTC in patients with elevated basal CT (bCT) following Pg-sCT and Ca-sCT stimulation and to compare the time courses of CT release during stimulation. Materials and methods: The stimulation tests were applied in 62 consecutive patients with thyroid nodules...
October 15, 2018: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/30412639/risk-factors-and-outcomes-of-incidental-parathyroidectomy-in-thyroidectomy-a-systematic-review-and-meta-analysis
#8
Binglong Bai, Zhiye Chen, Wuzhen Chen
INTRODUCTION: Postoperative hypocalcemia is the most common complication of thyroidectomy. Incidental parathyroidectomy (IP) was thought to be associated with postoperative hypocalcemia. However, according to previous studies, the risk factors and clinical outcomes of IP remain controversial. METHODS: Eligible studies were searched in databases including PubMed, Web of Science, and EMBASE from January 1990 to September 2017. Articles focusing on the relationship between IP and postoperative hypocalcemia were included...
2018: PloS One
https://www.readbyqxmd.com/read/30407335/lithium-intoxication-presenting-as-altered-consciousness-and-arrhythmia-with-cardiogenic-shock-a-case-report
#9
Shun-Ching Chien, Kuan-Ting Liu, Yen-Hung Wu
RATIONALE: Lithium has been used to treat bipolar disorder. Lithium has a narrow therapeutic index, with a therapeutic level between 0.6 and 1.5 mEq/L. The possible complications of lithium overdose include altered mental status, hand tremor, muscle weakness, nausea, vomiting, diarrhea, seizure, syncope, and arrhythmia. Lithium intoxication can be fatal and is difficult to diagnose in patients without a history of lithium intake. The occurrence of serious cardiac arrhythmias is rare in lithium intoxication...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30361076/lymph-node-ratio-predicts-recurrence-in-pediatric-papillary-thyroid-cancer
#10
Jill C Rubinstein, Catherine Dinauer, Kayleigh Herrick-Reynolds, Raffaella Morotti, Glenda G Callender, Emily R Christison-Lagay
BACKGROUND: Regional lymph node (LN) metastasis at the time of presentation plays a significant role in predicting recurrence in patients with papillary thyroid cancer (PTC). Multiple studies in the adult population have demonstrated that the lymph node ratio (LNR) in both the central and lateral neck can improve the accuracy of recurrence prediction, but this ratio has not been studied in the pediatric population. In this study, we sought to investigate the LNR in the central and lateral compartments as a prognostic predictor for recurrence in pediatric patients with PTC...
October 5, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30358210/multifocality-as-independent-prognostic-factor-in-papillary-thyroid-cancer-a-multivariate-analysis
#11
Ivan Markovic, Merima Goran, Nikola Besic, Marko Buta, Igor Djurisic, Dejan Stojiljkovic, Milan Zegarac, Gordana Pupic, Zorka Inic, Radan Dzodic
PURPOSE: The incidence of multifocality of papillary thyroid carcinoma (PTC) ranges from 18 to 87.5% The mechanisms of multifocal spreading, correlation with tumor size, histology variants of PTC, lymph node metastases, and prognostic impact remains unclear. The purpose of this study was to clarify the prognostic significance of multifocality on relapse and survival rates of patients with PTC by analyzing the correlation of multifocality with patient age, gender, tumor size, histological variants of PTC, presence of lymph node metastases and extent of surgery...
July 2018: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/30349900/phantom-nodules-detected-by-ultrasound-examination-of-the-neck-the-possibility-of-ectopic-cervical-thymic-tissue-in-adults
#12
Hisashi Ota, Mitsuyoshi Hirokawa, Ayana Suzuki, Maki Oshita, Aki Ito, Mitsuhiro Fukushima, Kaoru Kobayashi, Akira Miyauchi
Purpose: The aim of this study was to investigate the ultrasound characteristics and clinical significance of slightly hyperechoic lesions, referred to as phantom nodules, in the perithyroidal area in patients. Materials and Methods: A total of 128 patients who underwent thyroidectomy with central neck lymph node dissection at Kuma Hospital in Hyogo, Japan were included in the study. We detected 16 phantom nodules during preoperative ultrasound examinations, defined as slightly hyperechoic masses located in the perithyroidal areas, in 13 of these 128 patients (10...
October 2018: Ultrasound International Open
https://www.readbyqxmd.com/read/30348606/predictors-for-central-lymph-node-metastases-in-cn0-papillary-thyroid-microcarcinoma-mptc-a-retrospect-analysis-of-1304-cases
#13
Qiang Zhang, Zhengmin Wang, Xianying Meng, Quan-Yang Duh, Guang Chen
BACKGROUND: Presence of lymph node metastases increases the risk of recurrence, but prophylactic central neck node dissection for patients with micropapillary thyroid cancer (mPTC) is controversial. We aim to find the clinical predictors of central lymph node metastases (CLNM) in patients with cN0 mPTC. METHODS: We retrospectively reviewed the clinicopathological and molecular genetic characteristics of 1304 patients with cN0 mPTC operated at the First Hospital of Jilin University between January 1, 2013 and May 31, 2016, all underwent thyroid lobectomy or total thyroidectomy with unilateral or bilateral prophylactic central neck dissection...
October 19, 2018: Asian Journal of Surgery
https://www.readbyqxmd.com/read/30344714/complete-endoscopic-radical-resection-of-thyroid-cancer-via-an-oral-vestibule-approach
#14
Cong Bian, Hui Liu, Xi-Yu Yao, Shu-Ping Wu, Yu Wu, Chang Liu, Tian-Shun Huang
The aim of the present study was to explore the feasibility, safety and effectiveness of complete endoscopic radical resection of thyroid cancer via an oral vestibule approach. A total of 60 patients with unilateral thyroid papillary carcinoma were divided into two groups. Half of them underwent complete endoscopic surgeries via an oral vestibule approach at the Department of Head and Neck Surgery of Fujian Cancer Hospital between November 2014 and December 2016. The other 30 patients underwent traditional open surgeries...
November 2018: Oncology Letters
https://www.readbyqxmd.com/read/30337508/parathyroid-carcinoma-a-single-institution-experience-and-a-review-of-the-international-literature
#15
Francesco Quaglino, Valentina Marchese, Riccardo Lemini, Alessandro Piovesan, Enrico Mazza, Tiziana Viora, Stefano Taraglio
INTRODUCTION: Parathyroid carcinoma (PC) is a slow-growing and very rare malignancy, representing less than 0.005% of all cancers. The rarity of PC makes it hard to create large-scale published series of patients affected by this condition. MATERIALS AND METHODS: We present four cases of PC treated in our Institution and analyze the most salient aspects of this disease highlighted in recent international literature. DISCUSSION AND COMMENTS: In our experience, in 3/4 cases, the clinical presentation of PC was not different compared to adenoma; therefore, the diagnosis was a post-operative histopathological surprise...
2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/30337503/parathyroid-carcinoma-a-single-institution-experience-and-a-review-of-the-international-literature
#16
Francesco Quaglino, Valentina Marchese, Riccardo Lemini, Alessandro Piovesan, Enrico Mazza, Tiziana Viora, Stefano Taraglio
INTRODUCTION: Parathyroid carcinoma (PC) is a slow-growing and very rare malignancy, representing less than 0.005% of all cancers. The rarity of PC makes it hard to create large-scale published series of patients affected by this condition. MATERIALS AND METHODS: We present four cases of PC treated in our Institution and analyze the most salient aspects of this disease highlighted in recent international literature. DISCUSSION AND COMMENTS: In our experience, in 3/4 cases, the clinical presentation of PC was not different compared to adenoma; therefore, the diagnosis was a post-operative histopathological surprise...
June 11, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/30314503/identifying-risk-factors-for-recurrence-of-papillary-thyroid-cancer-in-patients-who-underwent-modified-radical-neck-dissection
#17
Young Jae Ryu, Jin Seong Cho, Jung Han Yoon, Min Ho Park
BACKGROUND: Papillary thyroid cancer (PTC) patients with ipsilateral neck metastatic lymph node (LN) and those with contralateral neck metastatic LN belong to N1b. Only a few studies have reported on comparisons with regard to laterality of metastatic lateral LN. The aim of this study was to evaluate predictive factors for contralateral neck LN metastasis and to determine prognostic factors for recurrence in PTC patients with N1b. METHODS: This retrospective study reviewed the medical records of 390 PTC patients who underwent total thyroidectomy and central LN dissection plus ipsilateral or bilateral modified radical neck dissection (MRND) between January 2004 and December 2012...
October 12, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/30302890/comparison-of-outcomes-between-hemithyroidectomy-alone-and-hemithyroidectomy-with-elective-unilateral-central-neck-dissection-in-patients-with-papillary-thyroid-microcarcinoma
#18
Ho Jin Son, Jeong Kyu Kim, Young Do Jung, Gyu Ho Jang, Youn Tae Seo, Deok Su Kim, Sung Hwan Park, Young Ju Jeong
BACKGROUND: There have been arguments over the efficacy of elective unilateral central neck dissection (CND) in patients with papillary thyroid carcinoma (PTC) <1 cm who underwent hemithyroidectomy. This study was designed to investigate locoregional recurrence and postoperative complications related to elective unilateral CND for papillary thyroid microcarcinoma (PTMC). METHODS: Five hundred thirty-seven patients who underwent hemithyroidectomy, with or without CND for PTMC, were included...
October 10, 2018: Head & Neck
https://www.readbyqxmd.com/read/30294871/braf-mutation-in-papillary-thyroid-cancer-prevalence-and-clinical-correlation-in-a-southeast-asian-cohort
#19
Xueying Goh, Jeffery Lum, Samantha Peiling Yang, Siok Bee Chionh, Evelyn Koay, Lily Chiu, Rajeev Parameswaran, Kee Yuan Ngiam, Thomas Kwok Seng Loh, Min En Nga, Chwee Ming Lim
OBJECTIVE: BRAF mutation is the commonest mutation seen in papillary thyroid cancer (PTC), but its prevalence and clinical significance vary across countries. We aim to evaluate the prevalence and clinico-pathological correlation of BRAF mutation in PTC patients at our center. STUDY DESIGN: Retrospective cohort study of 75 consecutive archival thyroid specimens, whereby BRAF mutation was detected using a polymerase chain reaction (PCR) technique and correlated with clinical and pathological features and outcomes...
October 8, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/30264276/the-learning-curve-of-endoscopic-thyroid-surgery-for-papillary-thyroid-microcarcinoma-cusum-analysis-of-a-single-surgeon-s-experience
#20
Jian Yu, Shangrui Rao, Zhe Lin, Zhongliang Pan, Xiangjian Zheng, Zhonglin Wang
BACKGROUND: With the development of surgical technics, endoscopic thyroid surgery has been gradually accepted and utilized in thyroid disease treatment, including thyroid carcinoma. This study aimed to evaluate the learning curve for endoscopic hemithyroidectomy (EHT) with ipsilateral central neck dissection (CND) and investigate how many cases must be performed before a surgeon becomes competent and proficient in this approach. METHODS: Ninety-nine consecutive patients who underwent EHT with ipsilateral CND for papillary thyroid microcarcinoma by a single surgeon between June 2015 and October 2017 were analyzed...
September 27, 2018: Surgical Endoscopy
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