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Varicella Encephalitis

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https://www.readbyqxmd.com/read/30102488/acute-peripheral-facial-paralysis-following-varicella-infection-an-uncommon-complication
#1
Damla Hanalioğlu, Yasemin Özsürekci, Ayşe Büyükçam, Ayşe Gültekingil-Keser, Özlem Tekşam, Mehmet Ceyhan
Hanalioğlu D, Özsürekci Y, Büyükçam A, Gültekingil-Keser A, Tekşam Ö, Ceyhan M. Acute peripheral facial paralysis following varicella infection: An uncommon complication. Turk J Pediatr 2018; 60: 99-101. Chickenpox is caused by varicella zoster virus (VZV/HHV-3), which is one of the eight human herpes viruses. Although chickenpox has a good prognosis, neurologic complications including encephalitis, acute cerebellar ataxia, myelitis and meningitis may seldom be associated with the disease. Peripheral facial palsy (PFP) is an extremely rare complication in patients with chickenpox...
2018: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/30083931/glycans-with-antiviral-activity-from-marine-organisms
#2
I D Grice, G L Mariottini
There remains today a critical need for new antiviral agents, particularly in view of the alarming increase in drug resistance and associated issues. The marine environment has been a prolific contributor towards the identification of novel therapeutic agents in the recent few decades. Added to this, glycans (or carbohydrate- or sugar-based compounds) have in very recent decades made outstanding contributions to the development of novel therapeutics. This review brings together these significant facets of modern drug discovery by presenting the reported literature on glycans derived from marine organisms that possess antiviral activity...
2018: Results and Problems in Cell Differentiation
https://www.readbyqxmd.com/read/30057855/epidemiology-of-vaccine-preventable-diseases-in-japan-considerations-for-pre-travel-advice-for-the-2019-rugby-world-cup-and-2020-summer-olympic-and-paralympic-games
#3
Matthew M Griffith, Munehisa Fukusumi, Yusuke Kobayashi, Yusuke Matsui, Shingo Nishiki, Reiko Shimbashi, Saeko Morino, Tomimasa Sunagawa, Keiko Tanaka-Taya, Tamano Matsui, Kazunori Oishi
Introduction: In 2019 and 2020, Japan will host two international sporting events estimated to draw a combined 22 million visitors. Mass gatherings like these ones increase the risk of spread of infectious disease outbreaks and international transmission. Pre-travel advice reduces that risk. Methods: To assist ministries of health and related organizations in developing pre-travel advice, we summarized national surveillance data in Japan (2000-2016, to the extent available) for rubella, invasive pneumococcal disease, measles, non-A and non-E viral hepatitis, hepatitis A, invasive Haemophilus influenzae disease, tetanus, typhoid fever, invasive meningococcal disease, Japanese encephalitis, influenza, varicella, mumps and pertussis by calculating descriptive statistics of reported cases and reviewing trends...
April 2018: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/30017769/post-arachnoiditis-anterior-spinal-arachnoid-cyst-formation-with-compressive-myelopathy-report-of-2-cases
#4
W Maenhoudt, R Rasschaert, H Bontinck, H Pinson, D Van Roost, G Hallaert
BACKGROUND: Spinal cystic arachnoiditis is a rare complication of a subarachnoid haemorrhage or infectious meningitis. The inflammatory process leads to fibrosis, adhesions and in severe cases to cyst formation. Large arachnoid cysts are an uncommon cause of compressive myelopathy. The majority are located posterior of the spinal cord at the thoracic level. Anterior cyst formation is exceptional, especially at the cervical region. CASE DESCRIPTION: We present two cases of progressive myelopathy secondary to anterior arachnoid cyst formation...
July 11, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29986093/high-viral-diversity-and-mixed-infections-in-cerebral-spinal-fluid-from-cases-of-varicella-zoster-virus-encephalitis
#5
Daniel P Depledge, Juliana Cudini, Samit Kundu, Claire Atkinson, Julianne R Brown, Tanzina Haque, Charlotte J Houldcroft, Evelyn S Koay, Fiona McGill, Richard Milne, Tom Whitfield, Julian W Tang, Gillian Underhill, Tomas Bergstrom, Peter Norberg, Richard Goldstein, Tom Solomon, Judith Breuer
Background: Varicella zoster virus (VZV) may cause encephalitis, both with and without rash. Here we investigate whether viruses recovered from the central nervous system (CNS; encephalitis or meningitis) differ genetically from those recovered from non-CNS samples. Methods: Enrichment-based deep sequencing of 45 VZV genomes from cerebral spinal fluid (CSF), plasma, bronchoalveolar lavage (BAL), and vesicles was carried out with samples collected from 34 patients with and without VZV infection of the CNS...
July 7, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29972576/encephalitis-associated-with-zika-virus-infection-and-reactivation-of-the-varicella-zoster-virus-in-a-brazilian-child
#6
Marcelo Adriano da Cunha E Silva Vieira, Alzira Almeida de Sousa Castro, Daniele Freitas Henriques, Eliana Vieira Pinto da Silva, Fernando Neto Tavares, Lívia Carício Martins, Lucas Melo Guimarães, Talita Antonia Furtado Monteiro, Raimunda do Socorro da Silva Azevedo, Ana Cecíclia Ribeiro Cruz, Pedro Fernando da Costa Vasconcelos
We report a case of encephalitis associated with Zika virus infection and reactivation of varicella-zoster virus in the central nervous system of a Brazilian child. This case raises the possibility that reactivation of the latent varicella-zoster virus may be a mechanism of neurological impairment induced by acquired Zika virus infection.
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29928710/a-case-of-cerebellar-ataxia-associated-with-vzv-infection
#7
Hirofumi Matsuyama, Takekazu Ohi
The varicella zoster virus (VZV) is a neurotropic virus that becomes latent in the sensory ganglia, but later causes various neurologic complications such as meningitis, encephalitis, myelitis, meningoencephalitis, cranial neuropathy, and peripheral neuropathy [1]. While acute cerebellitis is one of the most frequent acute cerebellar diseases associated with VZV in childhood, VZV rarely causes cerebellitis in adults, with or without skin manifestations, and only a few isolated cases of adult VZV cerebellitis have been reported...
June 2018: ENeurologicalSci
https://www.readbyqxmd.com/read/29921616/study-of-complications-of-varicella-zoster-virus-infection-in-hospitalized-children-at-a-reference-hospital-for-infectious-disease-treatment
#8
Lilian Martins Oliveira Diniz, Marcelle Marie Martins Maia, Yara Vieira de Oliveira, Marina Santos Falci Mourão, Amanda Vieira Couto, Vânia Carneiro Mota, Carolina Mazieiro Versiani, Priscila Olívia da Costa Silveira, Roberta Maia Castro Romanelli
OBJECTIVES: Varicella is a disease with potentially severe complications. We aimed to investigate characteristics of hospitalized children with varicella in Brazil in the prevaccine period and to identify predictors for requiring intensive care treatment. METHODS: A prospective cohort study was conducted from May 2011 to April 2014. Patients up to 13 years of age with varicella diagnosis were included. Information was collected through interview and review of medical records...
July 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29913285/epidemiology-and-clinical-outcomes-of-viral-central-nervous-system-infections
#9
Fatma Ben Abid, Mohammed Abukhattab, Hafedh Ghazouani, Obada Khalil, Ahmed Gohar, Hussam Al Soub, Muna Al Maslamani, Abdullatif Al Khal, Eman Al Masalamani, Said Al Dhahry, Samar Hashim, Faraj Howadi, Adeel A Butt
BACKGROUND: Central nervous system (CNS) viral infections are an important cause of morbidity and mortality. No data are available regarding their epidemiology in Qatar. DESIGN: We retrospectively evaluated all cerebrospinal fluid findings from January 2011-March 2015 at Hamad Medical Corporation. Those with abnormal CSF finding were included in our study. We excluded those with missing medical records, no clinical evidence of viral CNS infection, or proven bacterial, fungal or tuberculosis CNS infection...
August 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29902492/analytical-validation-of-viral-cns-flow-chip-kit-for-detection-of-acute-meningitis-and-encephalitis
#10
Mercedes Pérez-Ruiz, Irene Pedrosa-Corral, Sara Sanbonmatsu-Gámez, Cristina Gómez-Camarasa, José María Navarro-Marí
A new molecular assay (Viral CNS Flow Chip kit, Master Diagnóstica, Spain) has been developed for the detection of eight viruses causing acute meningitis and encephalitis, i.e. herpes simplex viruses 1-2, varicella zoster virus, human enterovirus, human parechovirus, Toscana virus, human cytomegalovirus and Epstein Barr virus. The new assay is a multiplex one-step RT-PCR followed by automatic flow-through hybridization, colorimetric detection and image analysis. The limit of detection was 50 copies/reaction, and 10 copies/reaction for human enterovirus and the other seven viruses, respectively...
September 2018: Journal of Virological Methods
https://www.readbyqxmd.com/read/29896664/neurological-disorders-associated-with-human-alphaherpesviruses
#11
Jun-Ichi Kawada
Herpes simplex virus (HSV) encephalitis is the most common cause of sporadic fatal encephalitis worldwide, and central nervous system (CNS) involvement is observed in approximately one-third of neonatal HSV infections . In recent years, single-gene inborn errors of innate immunity have been shown to be associated with susceptibility to HSV encephalitis . Temporal lobe abnormalities revealed by magnetic resonance imaging-the most sensitive imaging method for HSV encephalitis-are considered strong evidence for the disease...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29801466/varicella-zoster-virus-infections-in-neurological-patients-a-clinical-study
#12
Thomas Skripuletz, Kaweh Pars, Alina Schulte, Philipp Schwenkenbecher, Özlem Yildiz, Tina Ganzenmueller, Maike Kuhn, Annette Spreer, Ulrich Wurster, Refik Pul, Martin Stangel, Kurt-Wolfram Sühs, Corinna Trebst
BACKGROUND: Varicella zoster virus (VZV) reactivation is a common infectious disease in neurology and VZV the second most frequent virus detected in encephalitis. This study investigated characteristics of clinical and laboratory features in patients with VZV infection. METHODS: Two hundred eighty two patients with VZV reactivation that were hospitalized in the department of neurology in the time from 2005 to 2013 were retrospectively evaluated. Results from cerebrospinal fluid (CSF) analysis were available from 85 patients...
May 25, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29784468/vaccines-and-the-risk-of-acute-disseminated-encephalomyelitis
#13
Yong Chen, Fubao Ma, Yuanling Xu, Xuhua Chu, Jinlin Zhang
BACKGROUND: It is important to examine the risk of Acute disseminated encephalomyelitis (ADEM) after vaccination. METHODS: We conducted a nested case-control study between January 2011 and December 2015. Four controls per case were matched for age, gender, address. An independent expert committee validated the diagnoses of cases and controls. Data on vaccinations were obtained from computerized vaccination records. The analyses were conducted with the use of conditional logistic regression...
June 18, 2018: Vaccine
https://www.readbyqxmd.com/read/29720076/paediatric-active-enhanced-disease-surveillance-paeds-annual-report-2015-prospective-hospital-based-surveillance-for-serious-paediatric-conditions
#14
Jocelynne E McRae, Helen E Quinn, Kristine Macartney
Introduction: The Paediatric Active Enhanced Disease Surveillance (PAEDS) network is a hospital-based active surveillance system employing prospective case ascertainment for selected serious childhood conditions, particularly vaccine preventable diseases and potential adverse events following immunisation (AEFI). PAEDS data is used to better understand these conditions, inform policy and practice under the National Immunisation Program, and enable rapid public health responses for certain conditions of public health importance...
September 1, 2017: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/29626035/varicella-zoster-encephalitis-cranial-nerve-neuropathies-and-takotsubo-syndrome-delving-further-into-the-pathogenesis
#15
John E Madias
No abstract text is available yet for this article.
March 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29622669/secular-trends-in-infection-related-mortality-after-kidney-transplantation
#16
Susanna Kinnunen, Pauli Karhapää, Auni Juutilainen, Patrik Finne, Ilkka Helanterä
BACKGROUND AND OBJECTIVES: Infections are the most common noncardiovascular causes of death after kidney transplantation. We analyzed the current infection-related mortality among kidney transplant recipients in a nationwide cohort in Finland. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Altogether, 3249 adult recipients of a first kidney transplant from 1990 to 2012 were included. Infectious causes of death were analyzed, and the mortality rates for infections were compared between two eras (1990-1999 and 2000-2012)...
May 7, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29531617/epidemiological-profile-of-acute-viral-encephalitis-in-a-sample-of-egyptian-children
#17
Bassant Meligy, Dalia Kadry, Iman H Draz, Huda Marzouk, Nevine R El Baroudy, Amira Sayed El Rifay
INTRODUCTION: Acute encephalitis syndrome (AES) is a considerable public health problem. AIM: This study was designed to describe the aetiology, demographic features, clinical picture, short-term outcome and risk factors of mortality of children with viral encephalitis in Egyptian children. METHODS: PCR detection of viruses in the CSF of pediatric patients admitted to the pediatric unit or ICU Cairo University Pediatric hospital presenting with encephalitis syndrome...
February 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29519969/-an-autopsy-case-of-meningoencephalitis-and-cerebral-infarction-that-developed-with-ramsay-hunt-syndrome-and-disseminated-herpes-zoster
#18
Nobuo Yamashiro, Takamura Nagasaka, Naoki Ooishi, Mai Tsuchiya, Ryusuke Takaki, Fumikazu Kobayashi, Kazumasa Shindo, Yoshihisa Takiyama
We report here the clinical presentation and subsequent autopsy of a 90-year-old man who developed small papules with pain and swelling in his right ear. On admission, he exhibited right facial nerve paralysis, neck stiffness and Kernig's sign. The cell count was elevated and the varicella-zoster virus-PCR was positive in the CSF. Brain magnetic resonance imaging showed hyperintense lesions in the left pons and left temporal lobe, in FLAIR images. We diagnosed the patient with Ramsay Hunt syndrome and meningoencephalitis due to varicella-zoster virus...
March 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29469780/non-dermatomal-varicella-zoster-skin-infection-disseminated-cutaneous-herpes-zoster-without-dermatome-in-an-immunosuppressed-woman
#19
Lindsay P Osborn, Philip R Cohen
Disseminated herpes zoster is defined as the presence of more than 20 lesions outside the dermatome. This unusual presentation is more common in immunosuppressed patients. Complications such as hepatitis, encephalitis, and pneumonitis are more likely in individuals with disseminated varicella zoster virus infection.A 63-year-old woman being treated for breast cancer developed multiple pustules and vesicles days after starting doxorubicin and cyclophosphamide chemotherapy. Ten individual lesions appeared on her chest, abdomen, back, and leg...
October 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29460860/aetiology-of-acute-encephalitis-syndrome-in-uttar-pradesh-india-from-2014-to-2016
#20
Parul Jain, Shantanu Prakash, Danish N Khan, Ravindra Kumar Garg, Rashmi Kumar, Amit Bhagat, V Ramakrishna, Amita Jain
Background & objectives: It is imperative to know the aetiology of acute encephalitis syndrome (AES) for patient management and policy making. The present study was carried out to determine the prevalence of common aetiological agents of AES in Uttar Pradesh (UP) state of India. Methods: Serum and/or CSF samples were collected from AES patients admitted at Gandhi Memorial and Associated Hospital, King George's Medical University, Lucknow, a tertiary care centre, UP during 2014-16...
October 2017: Journal of Vector Borne Diseases
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