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Preterm AND NICU

Alexander Procaskey, Heather White, Tregony Simoneau, Nadav Traeger, Thomas Lahiri, Elie Abu Jawdeh, Ted Kremer, Catherine Sheils, Kathleen Meyer, Ted Rosenkrantz, Krishnan Sankaran, Tyler Hartman, Henry Feldman, Lawrence Rhein
Improved survival among preterm infants has led to an increase in diagnosis of chronic lung disease and infants discharged home from the NICU on supplemental oxygen. Despite this increased prevalence, no clearly defined guidelines for the management of home oxygen therapy (HOT) exist. This lack of consensus leads to significant variability in the duration of home oxygen therapy and a general paucity of evidence-based practice. Our team has identified recorded home oxygen therapy (RHO) as a potential new resource to guide clinical decision making in the outpatient pulmonology clinic...
August 11, 2018: Contemporary Clinical Trials
Jin-Hua Liao, Rong-Fang Hu, Li-Jing Su, Shuo Wang, Qin Xu, Xiao-Fang Qian, Hong-Gu He
BACKGROUND: Nonpharmacological interventions are often used to promote sleep among preterm infants in the neonatal intensive care unit (NICU). However, there is a lack of synthesis in the evidence of their effectiveness. AIM: To synthesize the evidence on the effectiveness of nonpharmacological interventions on NICU preterm infants' sleep during hospital stay. METHODS: Seven databases were searched, including MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Wan-fang database, China National Knowledge Infrastructure, China Biological Medicine Database, and VIP Journal Integration Platform from their inceptions to August 2017...
August 11, 2018: Worldviews on Evidence-based Nursing
Rita C Silveira, Eliane Wagner Mendes, Rubia Nascimento Fuentefria, Nadia Cristina Valentini, Renato S Procianoy
BACKGROUND: Preterm infants are high risk for delayed neurodevelopment. The main goal is to develop a program of early intervention for very preterm infants that allows families to apply it continuously at home, and quantify the results of early parental stimulation on improvement of cognition and motor skills. METHODS: Randomized clinical Trial including inborn preterm infants with gestational age less than 32 weeks or birth weight less than 1500 g at 48 h after birth...
August 9, 2018: BMC Pediatrics
Vivek Shukla, Apurva Chapla, Jigar Uperiya, Archana Nimbalkar, Ajay Phatak, Somashekhar Nimbalkar
OBJECTIVE: To compare the efficacy of SSC with oral Sucrose for pain management in preterm neonates. METHODOLOGY: Parallel-group, assessor-blinded randomized control trial conducted from February-June 2017 at a level 3B-NICU. Hundred preterm neonates (29-0/7 to 36-6/7 weeks gestational age) requiring heel-stick were randomly assigned (1:1), to SSC (50, Group-A) and Sucrose (50, Group-B). In Group-A, SSC was provided at least 10 min before the procedure. In Group-B, 0...
August 7, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
Hiie Soeorg, Sirli Treumuth, Hanna Kadri Metsvaht, Imbi Eelmäe, Mirjam Merila, Mari-Liis Ilmoja, Irja Lutsar, Tuuli Metsvaht
OBJECTIVE: We aimed to determine factors associated with gut colonization of preterm neonates with coagulase-negative staphylococci (CoNS) from maternal milk (MM). STUDY DESIGN: CoNS isolated from weekly collected stool and MM of hospitalized preterm (n = 49) and healthy term neonates (n = 20) were genotyped. Colonization-related factors were determined by Cox proportional hazards regression. RESULT: Gut colonization with mecA-negative Staphylococcus epidermidis from MM was less prevalent (40...
August 3, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
Alexandros Sotiriadis, George Makrydimas, Stefania Papatheodorou, John Pa Ioannidis, Emma McGoldrick
BACKGROUND: Infants born at term by elective caesarean section are more likely to develop respiratory morbidity than infants born vaginally. Prophylactic corticosteroids in singleton preterm pregnancies accelerate lung maturation and reduce the incidence of respiratory complications. OBJECTIVES: The objective of this review was to assess the effect of prophylactic corticosteroid administration before elective caesarean section at term, as compared to usual management without corticosteroids, in reducing neonatal respiratory morbidity and admission to special care with respiratory complications...
August 3, 2018: Cochrane Database of Systematic Reviews
Madhusudan Dey, Monica Saraswat
Background: Higher-order multiple (HOM) pregnancies are associated with increased incidences of pregnancy complications mainly abortions, pre-eclampsia, preterm delivery and fetal death. Multifetal reduction (MFR) during first trimester and subsequent delivery of twins can reduce pregnancy associated morbidities. This study was conducted to evaluate the maternal and fetal outcomes of MFR procedure in patients with HOMs those managed in a tertiary care hospital. Methods and Material: It was a prospective observational study carried out in a tertiary care military hospital, India, and all women with higher-order multiples (triplets or more) conceived spontaneously or after infertility treatment (ovulation induction, intra-uterine insemination, or in vitro fertilization) during the 3-year period from Jan 2014 to Dec 2016 were included for MFR...
August 2018: Journal of Obstetrics and Gynaecology of India
Yuanyuan Yang, Rui Li, Jing Wang, Qingying Huang, Hong Lu
BACKGROUND: Support from healthcare professionals has been identified as an important variable affecting successful breastfeeding in preterm infants. This study aimed to explore the knowledge of healthcare providers regarding breastfeeding preterm infants in mainland China. METHODS: An online cross-sectional survey of healthcare providers from 9 tertiary level neonatal intensive care units across 4 districts in mainland China was conducted from May-November, 2017...
July 31, 2018: BMC Pediatrics
Rudresh Deepak Shirwaikar
The decision-making process for estimating the optimal dosage is critical in clinical settings. In the neonatal intensive care unit (NICU), preterm neonates suffering from apnea of prematurity, optimum drug dosage can make a difference between life and death. To improve clinical decision making in the NICU, we have developed prediction models using machine learning algorithms. We have used optimized Support Vector Machine (SVM), decision trees with ensembles created using Bagging, Boosting, Random Forest, optimized Multi Layer Perceptron (MLP) and Deep Learning to predict adequacy of caffeine, a methylxanthine used to prevent the development of recurrent apneas, to reduce the need for mechanical ventilation...
2018: Critical Reviews in Biomedical Engineering
O Forner, A Schiby, A Ridley, G Thiriez, I Mugabo, V Morel, B Mulin, J-C Filiatre, D Riethmuller, G Levy, D Semama, D Martin, C Chantegret, S Bert, F Godoy, P Sagot, T Rousseau, A Burguet
OBJECTIVES: Mortality rates of very preterm infants may vary considerably between healthcare facilities depending on the neonates' place of inclusion in the cohort study. The objective of this study was to compare the mortality rates of live-born extremely preterm neonates observed in two French tertiary referral hospitals, taking into account the occurrence of neonatal death both in the delivery room and in the neonatal intensive care unit (NICU). METHODS: Retrospective observational study including all pregnancy terminations, stillbirths and live-born infants within a 22- to 26-week 0/6 gestational age range was registered by two French level 3 university centers between 2009 and 2013...
July 21, 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Thao T Griffith, Aleeca F Bell, Rosemary White-Traut, Barbara Medoff-Cooper, Kristin Rankin
OBJECTIVE: Primary: to identify the potential relationship between duration of tube feeding and success of oral feeding in preterm infants; secondary: to identify the potential relationships among duration of tube feeding and alert behavioral states, orally directed behaviors, and nutritive sucking. DESIGN: A descriptive correlational study. SETTING: A Level III NICU at an inner-city hospital. PARTICIPANTS: Twenty-eight preterm infants who were born between 28 and 32 weeks gestational age, were clinically stable, and were expected to have at least 1 week of tube feeding during their initial hospitalizations...
July 21, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
A Aslam, M Vincer, A Allen, S Imanullah, C M O'Connell
BACKGROUND: Normal saline bolus is commonly used in clinical practice for treating hypotension in very preterm infants during resuscitation at an early age despite the paucity of high quality evidence supporting this practice. OBJECTIVES: To determine the effects of early (<7 days after birth) saline boluses given to very preterm infant (VPI) from 23 to 31 weeks GA. METHOD: This is a population-based cohort analysis of the use of normal saline boluses given to VPI...
July 19, 2018: Journal of Neonatal-perinatal Medicine
Vibhuti Shah, Kate Hodgson, Mary Seshia, Michael Dunn, Georg M Schmölzer
Objectives: To determine 'Golden Hour' resuscitation and stabilization practices for infants <32 weeks gestational age in Canadian neonatal intensive care units (NICUs). Methods: A survey was distributed to investigators of the Evidence-based Practice for Improving Quality study within the Canadian Neonatal Network in June 2014. The questionnaire was designed to obtain information on antenatal counselling, resuscitation environment, resuscitation and management practices, including respiratory and nutritional practices in the first hour of life...
July 2018: Paediatrics & Child Health
Tiffany Herrero, Amy Driebe, Victoria Fratto, Alyssa Hamlin, D Yvette Lacoursiere, Gladys A Ramos
OBJECTIVE: We hypothesized that women with a positive antenatal Edinburgh Depression Screen (EPDS) (≥10), undergoing behavioral or pharmacologic therapy have improved maternal and neonatal outcomes. STUDY DESIGN: This is a retrospective study of singleton pregnancies at UC, San Diego from 2010 to 2014. Patients with an antenatal EPDS were subdivided based on their intervention: negative score, positive score no treatment, behavioral therapy only, and pharmacologic therapy...
July 22, 2018: Journal of Maternal-fetal & Neonatal Medicine
Hossein Zeraati, Fatemeh Nasimi, Akram Rezaeian, Javad Shahinfar, Maryam Ghorban Zade
Objectives: Preterm birth is considered as a risk factor for developmental disabilities, which can lead to long-term effects on the nervous system of children. The aim of this study was to determine the effect of multi-sensory stimulation on neurodevelopment of premature infants. Materials and Methods: In this two-group double-blind clinical trial in Jahrom Hospital, Jahrom, Iran from Jun to Aug 2016, 80 preterm infants were randomly divided. The intervention group received multisensory stimulation for 12 min per session, 5 sessions per wk along with routine NICU care and the control group received ward's routine care...
2018: Iranian Journal of Child Neurology
Damian Warzecha, Eliza Kobryń, Marta Bagińska, Dorota Bomba-Opoń
BACKGROUND: Fetal growth restriction (FGR) is an unclearly defined condition described as a fetal weight which is too low in relation to gestational age. It is recognized in 10-15% of singleton pregnancies and can lead to severe complications, including stillbirth. To reduce the adverse fetal and neonatal outcomes, many medical interventions are being introduced by obstetricians. These, like all medical procedures, may induce further complications, such as preterm labor and its consequences...
July 19, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Zongjian Yang, Hai Phung, Louise Freebairn, Rosalind Sexton, Alexandra Raulli, Paul Kelly
AIMS: Maternal overweight and obesity in pregnancy are known to increase the risk of a range of complications and adverse pregnancy outcomes. This study estimates the population-level contribution of maternal overweight and obesity to adverse pregnancy outcomes. METHODS: Data derived from the Australian Capital Territory (ACT) Maternal and Perinatal Data Collection were analysed. A total of 24 161 women who had a singleton birth in 2009-2015, with maternal weight and height information available, were included...
July 19, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
C Pisoni, S Spairani, F Fauci, G Ariaudo, C Tzialla, C Tinelli, P Politi, U Balottin, M Stronati, S Orcesi
BACKGROUND: The literature shows that parents of preterm infants are at risk of psychological distress and that this may impact on the quality of the parent-child relationship and on the child's development. AIM: This longitudinal study was conducted to examine in preterm infants relationships between maternal psychological variables, parental protective factors, perinatal infant variables, and neurodevelopmental outcome. Furthermore, we explored the impact of these variables on the quality of the mother-infant relationship (dyadic synchrony)...
July 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
Emriye Hilal Yayan, Sibel Kucukoglu, Yeliz Suna Dag, Nazlı Karsavuran Boyraz
BACKGROUND: Body position affects the gastric emptying rate and hence the amount of gastric residue. OBJECTIVE: This study aims to analyze the effect of the post-feeding position of preterm infants on gastric residue. MATERIALS AND METHODS: This experimental study was conducted in the neonatal intensive care unit (NICU) of a university hospital (İnönü University Turgut Özal Medical Center) in Eastern Turkey. The study included 40 preterm infants weighing less than 2,000 g, who were fed orogastrically...
July 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
Adziri H Sackey, Lily G Tagoe
Background: Antenatal corticosteroids (ACS) are established as an effective method of reducing preterm morbidity and mortality. At the Korle Bu Teaching Hospital (KBTH), a tertiary referral centre in Ghana, it is recommended that a course of ACS should be given to mothers before delivery between 24 weeks to 34 weeks gestation. Objectives: The study was performed primarily to determine the level of adherence to guidelines on administration of ACS. Methods: All babies with gestational ages up to 34 weeks admitted to the neonatal unit (NICU) during the period of the study were eligible for inclusion...
March 2018: Ghana Medical Journal
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