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Preterm AND NICU

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https://www.readbyqxmd.com/read/30514388/intensity-of-perinatal-care-extreme-prematurity-and-sensorimotor-outcome-at-2-years-corrected-age-evidence-from-the-epipage-2-cohort-study
#1
Andrei S Morgan, Laurence Foix L'Helias, Caroline Diguisto, Laetitia Marchand-Martin, Monique Kaminski, Babak Khoshnood, Jennifer Zeitlin, Gérard Bréart, Xavier Durrmeyer, François Goffinet, Pierre-Yves Ancel
BACKGROUND: Emerging evidence suggests intensity of perinatal care influences survival for extremely preterm babies. We evaluated the effect of differences in perinatal care intensity between centres on sensorimotor morbidity at 2 years of age. We hypothesised that hospitals with a higher intensity of perinatal care would have improved survival without increased disability. METHODS: Foetuses alive at maternal admission to a level 3 hospital in France in 2011, subsequently delivered between 22 and 26 weeks gestational age (GA) and included in the EPIPAGE-2 national prospective observational cohort study formed the baseline population...
December 5, 2018: BMC Medicine
https://www.readbyqxmd.com/read/30513031/neonatal-acute-liver-failure-due-to-enteroviruses-a-14-years-single-nicu-experience
#2
Iliana Bersani, Cinzia Auriti, Fiammetta Piersigilli, Andrea Dotta, Francesca Diomedi-Camassei, Alessandra Di Pede, Gabriele Buttinelli, Olivier Danhaive
BACKGROUND: Neonatal acute liver failure (ALF) is a severe condition with a mortality rate up to 70%. Human enterovirus (HEV) infections are associated with serious diseases in newborns, including myocarditis, meningoencephalitis and, more rarely, ALF with a fulminant course. METHODS: Cases of neonatal-onset ALF were identified using the institutional clinical database. The history and clinical data of infants with HEV infection were collected by medical record revision...
December 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30482067/fetal-abdominal-circumference-in-the-second-trimester-and-prediction-of-small-for-gestational-age-at-birth
#3
Georgios Doulaveris, Patience Gallagher, Elizabeth Romney, Michael Richley, Juliana Gebb, Mara Rosner, Dar M D Pe'er
BACKGROUND: Infants that are small for gestational age (SGA) at birth are at increased risk for morbidity and mortality. Unfortunately, the antenatal prediction of SGA is suboptimal. OBJECTIVES: We sought to: 1. examine the association between second trimester fetal abdominal circumference < 10% (2T-AClag) with SGA and other gestational and neonatal adverse outcomes; 2. assess 2T-AClag as a predictor of SGA. STUDY DESIGN: Retrospective study of 212 singleton gestations with 2T-AClag on routine ultrasound between 18-24 weeks...
November 27, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30477847/physiological-and-emotional-effects-of-pentatonic-live-music-played-for-preterm-neonates-and-their-mothers-in-the-newborn-intensive-care-unit-a-randomized-controlled-trial
#4
A Ranger, E Helmert, T S Bott, T Ostermann, H Als, D Bassler, M Hautzinger, J Vagedes
OBJECTIVE: Despite attempts to increase calmness in the Newborn Intensive Care Unit (NICU), preterm neonates still experience stress. The question arises how to further promote the infants' wellbeing. Therefore, the immediate effects of pentatonic live music on preterm infants and their mothers were examined. DESIGN AND METHODS: In a two-centre randomized controlled trial with crossover design preterm infants were exposed sequentially to two conditions: live pentatonic harp music (LPHM) used in Anthroposophic Medicine or standard care...
December 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/30459389/radiation-exposure-by-digital-radiographic-imaging-in-very-low-birth-weight-infants
#5
Chinedu U Ebenebe, Christophe Barreau, Jonathan Waschkewitz, Helmut Schlattl, Hans O Pinnschmidt, Philipp Deindl, Dominique Singer, Jochen Herrmann
OBJECTIVE: The aim of this study was to determine the cumulative effective doses (CED) from digital radiographic imaging in very low birth weight infants treated in a tertiary care neonatal intensive care unit (NICU). STUDY DESIGN: The CED for each infant was retrospectively calculated using a voxel-based model. The results were compared with previous studies applying conventional radiography. RESULTS: Two hundred and six preterm infants were included into this study...
November 20, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/30453908/perinatal-outcomes-in-twin-pregnancies-complicated-by-maternal-morbidity-evidence-from-the-who-multicountry-survey-on-maternal-and-newborn-health
#6
Danielly S Santana, Carla Silveira, Maria L Costa, Renato T Souza, Fernanda G Surita, João P Souza, Syeda Batool Mazhar, Kapila Jayaratne, Zahida Qureshi, Maria H Sousa, Joshua P Vogel, José G Cecatti
BACKGROUND: Twin pregnancy was associated with significantly higher rates of adverse neonatal and perinatal outcomes, especially for the second twin. In addition, the maternal complications (potentially life-threatening conditions-PLTC, maternal near miss-MNM, and maternal mortality-MM) are directly related to twin pregnancy and independently associated with adverse perinatal outcome. The objective of the preset study is to evaluate perinatal outcomes associated with twin pregnancies, stratified by severe maternal morbidity and order of birth...
November 20, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/30452096/employing-a-nutrition-nurse-in-neonatal-intensive-care-unit-improved-nutrition-and-growth-outcomes-in-preterm-neonates
#7
Ozge Aydemir, Adviye Cakık Saglık, Zekiye Sekili, Ayşe Neslihan Tekin
BACKGROUND: Nutrition nurses are clinical nurse specialists with knowledge and experience in nutrition support. We aimed to investigate the nutrition and growth outcomes after employment of a nutrition nurse in our level III neonatal intensive care unit (NICU). METHODS: A retrospective cohort study including preterm neonates < 34 weeks and < 2000 g were conducted. Nutrition and growth outcomes of infants in pre-nutrition-nurse and post-nutrition-nurse periods were compared...
November 19, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/30430530/extremely-preterm-infants-in-tunisia-where-are-we-now
#8
Fatma Zohra Chioukh, Karim Ben Ameur, Nédia Kasdallah, Sonia Blibech, Emira Ben Hamida, Imen Ayadi, Héchmi Ben Hamouda, Habib Soua, Manel Charfi, Nédia Hamida, Kamel Monastiri, Mohamed Douagi, Zahra Marrakchi, Abdellatif Gargouri
BACKGROUND: Extremely preterm infants are newborns born before 28 weeks of gestation. Survival of these immature newborns depends on resuscitation and the quality of care during hospitalization. OBJECTIVE: To determine survival and neurologic outcomes at2 years after extremely preterm birth. METHODS: It is a retrospective multicentric study in 5 neonatal intensive care units (NICU) in 2012-2013.All live births less than 28 weeks gestation were included...
August 2018: La Tunisie Médicale
https://www.readbyqxmd.com/read/30427555/investigation-of-stress-and-nursing-support-in-mothers-of-preterm-infants-in-neonatal-intensive-care-units
#9
Sevinc Akkoyun, Fatma Tas Arslan
BACKGROUND: The birth and hospitalisation of a premature infant in a neonatal intensive care unit (NICU) are stressful experiences for the mother and the family. The support of neonatal nurses is necessary to control and reduce the stress of mothers. And nurse-parent support may play a role in effective stress management and make a positive contribution to the health of mothers. AIM: To determine the correlation of stress and nurse-parent support levels with mothers' age and educational status, number of children, gestational week of the infant and the hospitalisation period of the infant among mothers of premature infants hospitalised in the NICU...
November 14, 2018: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/30417761/pregnancy-and-perinatal-outcome-among-hypothyroid-mothers-a-population-based-cohort-study
#10
Suvi Turunen, Marja Vääräsmäki, Tuija Männistö, Anna-Liisa Hartikainen, Anna-Maria Lahesmaa-Korpinen, Mika Gissler, Eila Suvanto
BACKGROUND: Maternal hypothyroidism has been associated with adverse pregnancy outcomes. We established a large nationwide register-based cohort with data on medication purchases to study the associations between maternal hypothyroidism, levothyroxine use and pregnancy and perinatal complications. METHODS: Our data included all singleton births between 2004 and 2013 (N=571,785) in Finland. Hypothyroid mothers (N=16,364) were identified in the Finnish Medical Birth Register...
November 12, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/30407512/short-term-pasteurization-of-breast-milk-to-prevent-postnatal-cytomegalovirus-transmission-in-very-preterm-infants
#11
Sascha Bapistella, Klaus Hamprecht, Wolfgang Thomas, Christian P Speer, Klaus Dietz, Jens Maschmann, Christian F Poets, Rangmar Goelz
Background: Postnatally acquired cytomegalovirus (pCMV) infection through breast milk (BM) may cause severe illness and even death, yet BM is advantageous for preterm infants. Therefore, effective methods to prevent its transmission are needed. Objective: To assess the effectiveness of short-term pasteurization (62°C for 5 seconds) in preventing CMV transmission via BM in preterm infants. Design: Prospective interventional bicentric cohort study with infant enrollment between 6/2010 and 1/2012...
November 8, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30406135/necrotizing-enterocolitis-in-moderate-preterm-infants
#12
Jayasree Nair, Rachel Longendyke, Satyan Lakshminrusimha
Necrotizing enterocolitis (NEC) is a devastating morbidity usually seen in preterm infants, with extremely preterm neonates (EPT ≤28 weeks) considered at highest risk. Moderately preterm infants (MPT 28-34 weeks) constitute a large percentage of NICU admissions. In our retrospective data analysis of NEC in a single regional perinatal center, NEC was observed in 10% of extremely EPT and 7% of MPT, but only 0.7% of late-preterm/term admissions. There was an inverse relationship between postnatal age at onset of NEC and gestational age at birth...
2018: BioMed Research International
https://www.readbyqxmd.com/read/30405557/viral-respiratory-infections-in-the-neonatal-intensive-care-unit-a-review
#13
REVIEW
Karin Pichler, Ojan Assadian, Angelika Berger
Although infrequent, respiratory viral infections (RVIs) during birth hospitalization have a significant impact on short- and long-term morbidity in term and preterm neonates. RVI have been associated with increased length of hospital stay, severe disease course, unnecessary antimicrobial exposure and nosocomial outbreaks in the neonatal intensive care unit (NICU). Virus transmission has been described to occur via health care professionals, parents and other visitors. Most at risk are infants born prematurely, due to their immature immune system and the fact that they stay in the NICU for a considerable length of time...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/30389541/-modalities-of-birth-in-case-of-uncomplicated-preterm-premature-rupture-of-membranes-cngof-preterm-premature-rupture-of-membranes-guidelines
#14
P Delorme, C Garabedian
OBJECTIVE: To identify the ideal gestational age at delivery for preterm premature rupture of membranes and modalities of birth. METHOD: To identify studies, research was conducted using Pub-Med, Embase and Cochrane databases. RESULTS: Prolonged latency duration after pPROM does not worsen neonatal prognosis (NP3). Therefore, it is recommended not to deliver before 34 weeks of gestation for patient with uncomplicated preterm rupture of membranes (pPROM) (Grade C)...
October 30, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/30374050/oxygen-desaturations-in-the-early-neonatal-period-predict-development-of-bronchopulmonary-dysplasia
#15
Karen D Fairchild, V Peter Nagraj, Brynne A Sullivan, J Randall Moorman, Douglas E Lake
BACKGROUND: Bradycardia and oxygen desaturation episodes are common among preterm very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU), and their association with adverse outcomes such as bronchopulmonary dysplasia (BPD) is unclear. METHODS: For 502 VLBW infants we quantified bradycardias (HR < 100 for ≥ 4 s) and desaturations (SpO2  < 80% for ≥ 10 s), combined bradycardia and desaturation (BD) events, and percent time in events in the first 4 weeks after birth (32 infant-years of data)...
October 29, 2018: Pediatric Research
https://www.readbyqxmd.com/read/30348961/successful-implementation-of-an-intracranial-hemorrhage-ich-bundle-in-reducing-severe-ich-a-quality-improvement-project
#16
Nicolas Chiriboga, Josef Cortez, Adriana Pena-Ariet, Kartikeya Makker, Carmen Smotherman, Shiva Gautam, Allison Blair Trikardos, Holly Knight, Mark Yeoman, Erin Burnett, Alexandra Beier, Inbal Cohen, Mark L Hudak
OBJECTIVE: Our specific, measurable, attainable, relevant, and time-limited (SMART) aim was to reduce the incidence of severe intracranial hemorrhage (ICH) among preterm infants born <30 weeks' gestation from a baseline of 24% (January 2012-December 2013) to a long-term average of 11% by December 2015. STUDY DESIGN: We instituted an ICH bundle consisting of elements of the "golden hour" (delayed cord clamping, optimized cardiopulmonary resuscitation, improved thermoregulation) and provision of cluster care in the neonatal intensive care unit (NICU)...
October 22, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/30344050/modelling-intestinal-glucose-absorption-in-premature-infants-using-continuous-glucose-monitoring-data
#17
J L Knopp, M Signal, D L Harris, G Marics, P Weston, J Harding, P Tóth-Heyn, J Hómlok, B Benyó, J G Chase
BACKGROUND: Model-based glycaemic control protocols have shown promise in neonatal intensive care units (NICUs) for reducing both hyperglycaemia and insulin-therapy driven hypoglycaemia. However, current models for the appearance of glucose from enteral feeding are based on values from adult intensive care cohorts. This study aims to determine enteral glucose appearance model parameters more reflective of premature infant physiology. METHODS: Peaks in CGM data associated with enteral milk feeds in preterm and term infants are used to fit a two compartment gut model...
October 3, 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/30328044/cup-feeding-as-a-supplemental-alternative-feeding-method-for-preterm-breastfed-infants-an-integrative-review
#18
REVIEW
Frances Penny, Michelle Judge, Elizabeth Brownell, Jacqueline M McGrath
Background The benefits of human milk for the preterm infant are well established. Preterm infants have lower breastfeeding rates and often face breastfeeding challenges. It is important that feeding practices for preterm infants optimize their chances of breastfeeding. Objective The purpose of this integrated review is to synthesize and critically analyze research related to the safety and efficacy of cup feeding as an alternative, supplemental feeding method for breastfed infants. Data Sources The electronic data bases of PubMed, CINAHL and were used to identify studies published in English from 1998- 2017...
November 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/30315272/brain-imaging-in-preterm-infants-32-weeks-gestation-a-clinical-review-and-algorithm-for-the-use-of-cranial-ultrasound-and-qualitative-brain-mri
#19
REVIEW
John Ibrahim, Imran Mir, Lina Chalak
The aim is to review the evidence about the utility of term-equivalent age (TEA) magnetic resonance imaging (MRI) in predicting neurodevelopmental outcomes for preterm neonates. Preterm birth accounts for ~12% of all deliveries in the United States and is the leading cause of neurologic disabilities in children. From the neonatologist perspective, it is critically important to identify preterm infants at risk of subsequent neurodevelopmental disability who may benefit from early intervention services. However "the choose wisely campaign" also emphasizes the need to have ongoing cost/benefit discussions regarding care of preterm newborns to avoid waste that comes from subjecting infants to procedures that do not help...
October 12, 2018: Pediatric Research
https://www.readbyqxmd.com/read/30304900/clinical-features-and-prognostic-factors-of-early-onset-sepsis-a-7-5-year-experience-in-one-neonatal-intensive-care-unit
#20
Se Jin Kim, Ga Eun Kim, Jae Hyun Park, Sang Lak Lee, Chun Soo Kim
Purpose: This study was undertaken to investigate the clinical features and prognostic factors of early-onset sepsis (EOS) in neonatal intensive care unit (NICU) patients. Methods: A retrospective analysis of the medical records was conducted in a NICU of a university hospital over a 7.5-year period (Jan 2010-Jun 2017). Results: During the study period, there were 45 (1.2%) episodes of EOS in 3,862 infants. The most common pathogen responsible for EOS was Streptococcus group B (GBS) in 10 cases (22...
September 27, 2018: Korean Journal of Pediatrics
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