G Pernod, P Albaladejo, A Godier, C M Samama, S Susen, Y Gruel, N Blais, P Fontana, A Cohen, J V Llau, N Rosencher, J F Schved, E de Maistre, M M Samama, P Mismetti, P Sié
New direct oral anticoagulants (NOAC), inhibitors of factor IIa or Xa, are expected to be widely used for the treatment of venous thromboembolic disease, or in case of atrial fibrillation. Such anticoagulant treatments are known to be associated with haemorrhagic complications. Moreover, it is likely that such patients on long-term treatment with NOAC will be exposed to emergency surgery or invasive procedures. Due to the present lack of experience in such conditions, we cannot make recommendations, but only propose management for optimal safety as regards the risk of bleeding in such emergency conditions...
October 2013: Annales Françaises D'anesthèsie et de Rèanimation